Best TWAS P=7.86e-09 · Best GWAS P=3.41e-07 conditioned to 0.84
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Frontal Cortex BA9 | PIGCP1 | 0.36 | 0.05 | enet | 35 | 0.07 | 7.5e-03 | -4.7 | -5.1 | 2.8e-07 | -0.61 | 0.02 | 0.88 | FALSE |
| 2 | GTEx | Cells Transformed fibroblasts | TCP11L1 | 0.17 | 0.07 | enet | 15 | 0.14 | 2.5e-10 | 3.0 | -5.6 | 2.4e-08 | -0.68 | 0.05 | 0.93 | FALSE |
| 3 | GTEx | Thyroid | PIGCP1 | 0.14 | 0.11 | enet | 32 | 0.11 | 4.8e-09 | -4.9 | -5.3 | 1.4e-07 | -0.61 | 0.02 | 0.97 | FALSE |
| 4 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | LOC283267 | 0.05 | 0.02 | blup | 50 | 0.04 | 6.0e-05 | -4.9 | -5.5 | 4.5e-08 | -0.82 | 0.02 | 0.96 | FALSE |
| 5 | The Cancer Genome Atlas | Thyroid Carcinoma | TCP11L1 | 0.11 | 0.04 | blup | 76 | 0.08 | 1.2e-08 | -4.9 | -5.8 | 7.9e-09 | -0.87 | 0.02 | 0.97 | TRUE |