[Hub]/) : Traits : Forced expiratory volume in 1-second (FEV1) :

chr11:46,565,407-48,360,648

Best TWAS P=7.64e-08 · Best GWAS P=6.03e-08 conditioned to 0.000333

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Colon Transverse C1QTNF4 0.07 0.02 lasso 6 0.03 2.0e-02 -5.2 5.3 1.2e-07 0.25 0.02 0.93 FALSE
2 GTEx Muscle Skeletal MTCH2 0.05 0.03 enet 15 0.04 1.5e-04 -4.5 -5.3 1.2e-07 -0.37 0.03 0.96 FALSE
3 GTEx Muscle Skeletal C1QTNF4 0.09 0.14 lasso 3 0.13 9.9e-13 -5.1 5.2 1.6e-07 0.26 0.01 0.99 FALSE
4 GTEx Whole Blood C1QTNF4 0.09 0.05 lasso 3 0.03 1.4e-03 -5.1 5.2 2.6e-07 0.22 0.02 0.97 FALSE
5 ROSMAP Brain Pre-frontal Cortex ACP2 0.03 0.00 blup 295 0.02 1.5e-03 -4.2 -5.1 3.0e-07 -0.64 0.20 0.51 FALSE
6 ROSMAP Brain Pre-frontal Cortex C1QTNF4 0.05 0.06 blup 281 0.06 1.7e-08 -4.3 5.4 7.6e-08 0.39 0.05 0.95 TRUE
7 YFS Blood PSMC3 0.02 0.01 blup 289 0.01 2.8e-05 -5.2 -5.1 2.8e-07 -0.36 0.02 0.96 FALSE
8 The Cancer Genome Atlas Esophageal Carcinoma C1QTNF4 0.39 0.33 blup 15 0.35 6.1e-12 -5.1 5.2 2.4e-07 0.25 0.00 0.99 FALSE
9 The Cancer Genome Atlas Lung Adenocarcinoma C1QTNF4 0.03 0.02 blup 15 0.02 1.3e-03 -5.1 5.4 8.1e-08 0.27 0.00 0.94 FALSE