[Hub]/) : Traits : Forced expiratory volume in 1-second (FEV1) :

chr11:72,325,482-74,006,925

Best TWAS P=4.74e-11 · Best GWAS P=1.05e-08 conditioned to 0.621

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex RELT 0.06 0.02 blup 318 0.04 4.1e-06 4.8 5.7 1.5e-08 0.71 0.06 0.91 FALSE
2 GTEx Spleen RP11-809N8.4 0.33 0.03 lasso 4 0.03 5.5e-02 4.4 5.2 1.6e-07 0.77 0.02 0.58 FALSE
3 GTEx Whole Blood ARHGEF17 0.15 0.16 lasso 3 0.16 8.6e-15 5.4 5.6 2.0e-08 0.97 0.01 0.99 FALSE
4 GTEx Whole Blood RP11-809N8.4 0.08 0.06 lasso 2 0.04 6.5e-05 5.2 5.4 7.7e-08 0.70 0.06 0.93 FALSE
5 GTEx Whole Blood RP11-800A3.7 0.19 0.11 enet 10 0.12 2.0e-11 5.4 5.7 1.1e-08 0.85 0.01 0.99 FALSE
6 NTR Blood RELT 0.04 0.05 lasso 5 0.04 1.8e-13 5.3 5.6 2.4e-08 0.66 0.04 0.96 FALSE
7 ROSMAP Brain Pre-frontal Cortex FAM168A 0.03 0.02 bslmm 358 0.02 2.6e-03 4.9 -6.6 4.7e-11 -0.83 0.07 0.88 TRUE
8 YFS Blood ARHGEF17 0.09 0.17 lasso 5 0.17 1.4e-53 5.7 5.6 1.9e-08 0.99 0.00 1.00 FALSE
9 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma RELT 0.06 0.07 blup 35 0.08 3.5e-09 5.3 5.4 6.6e-08 0.78 0.02 0.98 FALSE
10 The Cancer Genome Atlas Stomach Adenocarcinoma ARHGEF17 0.04 0.03 blup 54 0.02 1.2e-02 5.5 5.7 1.2e-08 0.91 0.01 0.78 FALSE