Best TWAS P=1.5e-08 · Best GWAS P=9.87e-11 conditioned to 0.00167
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | ANGPTL1 | 0.05 | 0.02 | lasso | 6 | 0.03 | 1.1e-04 | -3.7 | -5.2 | 1.7e-07 | -0.81 | 0.04 | 0.96 | FALSE |
| 2 | GTEx | Artery Aorta | ANGPTL1 | 0.14 | 0.08 | lasso | 3 | 0.07 | 7.4e-05 | 6.4 | 5.7 | 1.5e-08 | 0.90 | 0.01 | 0.97 | TRUE |
| 3 | The Cancer Genome Atlas | Lung Adenocarcinoma | ANGPTL1 | 0.07 | 0.04 | blup | 42 | 0.05 | 2.3e-06 | -3.7 | 5.6 | 1.9e-08 | 0.74 | 0.05 | 0.92 | FALSE |