[Hub]/) : Traits : Forced expiratory volume in 1-second (FEV1) : ← →

chr1:149,672,809-151,659,071

Best TWAS P=9.65e-10 · Best GWAS P=2.67e-09 conditioned to 0.0341

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
12	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	PPIAL4C	0.06	0.03	enet	6	0.04	1.3e-04	-5.1	-6.1	9.7e-10	-0.03	0.00	0.64	TRUE
5	GTEx	Esophagus Muscularis	CTSS	0.05	0.04	enet	12	0.06	1.2e-04	4.6	6.1	1.4e-09	0.71	0.10	0.85	TRUE
16	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	CTSS	0.16	0.08	enet	8	0.07	1.6e-05	-4.9	5.7	9.1e-09	0.69	0.01	0.96	FALSE
3	GTEx	Breast Mammary Tissue (Male)	SETDB1	0.13	0.00	enet	7	0.04	3.8e-02	5.1	-5.7	1.1e-08	-0.50	0.06	0.20	FALSE
2	GTEx	Brain Hypothalamus	RP11-316M1.12	0.14	0.03	lasso	6	0.02	9.9e-02	5.1	-5.6	1.7e-08	-0.81	0.08	0.30	FALSE
6	GTEx	Muscle Skeletal	CTSS	0.04	0.01	enet	13	0.03	1.4e-03	5.4	5.6	2.2e-08	0.81	0.06	0.88	FALSE
7	GTEx	Skin Not Sun Exposed Suprapubic	ANXA9	0.11	0.12	lasso	2	0.13	2.0e-07	-4.9	5.6	2.5e-08	0.58	0.11	0.82	FALSE
13	The Cancer Genome Atlas	Breast Invasive Carcinoma	CTSS	0.02	0.01	enet	4	0.01	2.8e-03	4.3	5.6	2.8e-08	0.73	0.02	0.76	FALSE
14	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	CTSS	0.04	0.01	enet	4	0.03	4.7e-04	4.6	5.4	6.9e-08	0.67	0.02	0.88	FALSE
11	GTEx	Thyroid	CTSS	0.15	0.12	enet	30	0.18	2.4e-13	4.4	5.4	7.7e-08	0.71	0.62	0.34	FALSE
8	GTEx	Skin Sun Exposed Lower leg	ANXA9	0.12	0.04	lasso	3	0.08	3.8e-07	-4.4	5.3	9.3e-08	0.57	0.18	0.81	FALSE
4	GTEx	Breast Mammary Tissue (Male)	RP11-54A4.2	0.07	0.01	enet	2	0.03	7.4e-02	-5.1	-5.3	1.1e-07	-0.74	0.03	0.25	FALSE
10	GTEx	Thyroid	ARNT	0.08	0.10	lasso	10	0.10	7.8e-08	-4.8	5.3	1.2e-07	0.91	0.02	0.98	FALSE
9	GTEx	Testis	CTSK	0.07	0.01	enet	19	0.01	1.2e-01	3.6	5.3	1.3e-07	0.75	0.18	0.48	FALSE
17	The Cancer Genome Atlas	Prostate Adenocarcinoma	GOLPH3L	0.03	0.01	blup	49	0.01	2.2e-02	4.3	-5.3	1.5e-07	-0.71	0.04	0.50	FALSE
15	The Cancer Genome Atlas	Brain Lower Grade Glioma	CTSS	0.29	0.08	lasso	3	0.08	1.5e-09	-4.9	5.2	2.1e-07	0.52	0.00	0.99	FALSE
1	GTEx	Brain Cerebellar Hemisphere	RP11-316M1.12	0.31	0.37	lasso	4	0.39	4.5e-11	4.1	-5.1	2.8e-07	-0.73	0.26	0.72	FALSE