TWAS
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Traits
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Forced expiratory volume in 1-second (FEV1)
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chr1:203,785,948-205,241,659
Best TWAS P=3.91e-08 · Best GWAS P=1.79e-08 conditioned to 0.0167
203.8M
204M
204.2M
204.4M
204.6M
204.8M
205M
205.2M
0
2
4
6
8
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
YFS
Blood
MDM4
0.12
0.08
bslmm
636
0.12
2.0e-36
4.2
5.5
3.9e-08
-0.72
0.67
0.29
TRUE
1
GTEx
Esophagus Muscularis
MDM4
0.14
0.05
lasso
4
0.05
8.6e-04
-5.2
-5.2
1.9e-07
0.97
0.02
0.98
FALSE