[Hub]/) : Traits : Forced expiratory volume in 1-second (FEV1) : ← →

chr12:55,677,395-57,082,058

Best TWAS P=5.48e-11 · Best GWAS P=1.16e-09 conditioned to 0.251

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
6	The Cancer Genome Atlas	Lung Adenocarcinoma	RAB5B	0.03	0.02	enet	7	0.02	4.3e-03	-5.9	-6.6	5.5e-11	0.83	0.00	0.83	TRUE
4	GTEx	Muscle Skeletal	AC034102.1	0.28	0.31	lasso	4	0.31	2.3e-31	-6.0	5.9	2.8e-09	-0.99	0.01	0.99	FALSE
2	GTEx	Muscle Skeletal	RAB5B	0.29	0.32	lasso	4	0.33	1.3e-33	-5.9	5.9	2.9e-09	-0.99	0.01	0.99	FALSE
9	The Cancer Genome Atlas	Skin Cutaneous Melanoma	RPS26	0.28	0.15	lasso	2	0.17	3.0e-05	-6.1	-5.8	5.1e-09	0.98	0.00	0.98	FALSE
8	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	RPS26	0.30	0.20	lasso	4	0.24	3.9e-16	-4.8	-5.6	2.1e-08	0.91	0.02	0.97	FALSE
3	GTEx	Muscle Skeletal	SUOX	0.11	0.04	lasso	7	0.04	4.4e-05	-4.8	5.3	1.3e-07	-0.82	0.25	0.68	FALSE
1	GTEx	Heart Atrial Appendage	SUOX	0.09	0.10	enet	8	0.09	1.1e-04	-4.8	5.2	1.9e-07	-0.82	0.07	0.82	FALSE
7	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	RPS26	0.22	0.31	lasso	3	0.31	1.6e-35	-4.8	-5.2	2.5e-07	0.84	0.65	0.35	FALSE
5	The Cancer Genome Atlas	Colon Adenocarcinoma	RPS26	0.43	0.48	lasso	4	0.47	1.8e-30	-4.8	-5.1	3.1e-07	0.84	0.59	0.41	FALSE