Best TWAS P=1.71e-08 · Best GWAS P=1.29e-06 conditioned to 0.617
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Colon Transverse | C1GALT1 | 0.32 | 0.23 | lasso | 4 | 0.30 | 8.0e-15 | -4.3 | -5.2 | 2.5e-07 | 0.89 | 0.02 | 0.95 | FALSE |
2 | GTEx | Esophagus Muscularis | C1GALT1 | 0.36 | 0.16 | lasso | 8 | 0.27 | 1.9e-16 | -4.6 | -5.2 | 2.7e-07 | 0.83 | 0.02 | 0.96 | FALSE |
3 | GTEx | Nerve Tibial | C1GALT1 | 0.44 | 0.28 | lasso | 12 | 0.40 | 2.0e-30 | -4.2 | -5.3 | 1.0e-07 | 0.82 | 0.03 | 0.93 | FALSE |
4 | GTEx | Pancreas | C1GALT1 | 0.44 | 0.11 | enet | 24 | 0.22 | 8.8e-10 | -4.2 | -5.6 | 1.7e-08 | 0.81 | 0.02 | 0.95 | TRUE |
5 | GTEx | Spleen | C1GALT1 | 0.56 | 0.29 | lasso | 6 | 0.46 | 3.2e-13 | -4.2 | -5.2 | 2.2e-07 | 0.71 | 0.05 | 0.84 | FALSE |
6 | GTEx | Stomach | C1GALT1 | 0.24 | 0.07 | enet | 17 | 0.12 | 1.9e-06 | -4.2 | -5.6 | 2.5e-08 | 0.83 | 0.02 | 0.93 | FALSE |
7 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | C1GALT1 | 0.16 | 0.12 | lasso | 7 | 0.14 | 3.7e-08 | -3.6 | -5.2 | 2.0e-07 | 0.83 | 0.02 | 0.95 | FALSE |
8 | The Cancer Genome Atlas | Prostate Adenocarcinoma | C1GALT1 | 0.12 | 0.05 | enet | 10 | 0.13 | 9.9e-14 | -4.3 | -5.2 | 2.0e-07 | 0.71 | 0.04 | 0.88 | FALSE |