[Hub]/) : Traits : Peak expiratory flow (PEF) : ← →

chr8:8,092,025-10,985,432

Best TWAS P=1.56e-11 · Best GWAS P=6.98e-12 conditioned to 0.00687

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	ERI1	0.06	0.04	lasso	3	0.04	9.0e-06	5.5	5.7	1.0e-08	-0.44	0.18	0.82	FALSE
2	GTEx	Adipose Subcutaneous	ERI1	0.05	0.00	enet	10	0.00	5.5e-01	-4.8	6.7	1.6e-11	-0.75	0.22	0.36	TRUE
3	GTEx	Artery Aorta	ERI1	0.11	0.08	lasso	5	0.10	5.1e-06	-4.1	5.3	1.1e-07	-0.71	0.64	0.32	FALSE
4	GTEx	Artery Tibial	ERI1	0.05	0.02	lasso	7	0.01	3.2e-02	-6.0	5.7	1.5e-08	-0.72	0.07	0.88	FALSE
5	GTEx	Brain Cerebellar Hemisphere	FAM86B3P	0.28	0.27	lasso	8	0.28	5.4e-08	-5.3	5.2	2.7e-07	-0.74	0.04	0.95	FALSE
6	GTEx	Cells Transformed fibroblasts	FAM86B3P	0.23	0.33	lasso	11	0.38	8.4e-30	-4.5	-5.4	5.3e-08	0.75	0.49	0.50	FALSE
7	GTEx	Esophagus Gastroesophageal Junction	MSRA	0.11	-0.01	enet	30	-0.01	8.0e-01	-6.0	5.1	2.7e-07	-0.67	0.03	0.82	FALSE
8	GTEx	Esophagus Muscularis	ERI1	0.12	0.09	enet	13	0.08	7.7e-06	-3.9	5.8	5.4e-09	-0.73	0.09	0.91	FALSE
9	GTEx	Lung	ERI1	0.13	0.07	lasso	6	0.09	2.7e-07	5.3	5.9	4.3e-09	-0.75	0.22	0.78	FALSE
10	GTEx	Lung	AC087269.1	0.20	0.19	lasso	9	0.18	4.8e-14	-5.1	5.6	1.7e-08	-0.50	0.58	0.41	FALSE
11	GTEx	Lung	CLDN23	0.18	0.17	lasso	7	0.16	2.5e-12	-5.1	5.5	3.1e-08	-0.48	0.61	0.39	FALSE
12	GTEx	Muscle Skeletal	MFHAS1	0.07	0.04	lasso	4	0.04	1.4e-04	-4.3	-5.6	2.2e-08	0.70	0.17	0.82	FALSE
13	GTEx	Nerve Tibial	ERI1	0.07	0.01	enet	16	0.01	4.2e-02	3.9	5.9	3.1e-09	-0.76	0.29	0.23	FALSE
14	GTEx	Skin Not Sun Exposed Suprapubic	AC087269.1	0.43	0.31	lasso	11	0.31	2.2e-17	-5.1	5.2	1.9e-07	-0.41	0.63	0.36	FALSE
15	GTEx	Skin Not Sun Exposed Suprapubic	CLDN23	0.42	0.30	lasso	12	0.30	7.6e-17	-5.1	5.2	1.7e-07	-0.41	0.64	0.36	FALSE
16	GTEx	Skin Sun Exposed Lower leg	AC087269.1	0.43	0.39	lasso	8	0.40	3.5e-35	-5.3	5.2	2.0e-07	-0.41	0.56	0.44	FALSE
17	GTEx	Skin Sun Exposed Lower leg	CLDN23	0.43	0.38	lasso	8	0.39	3.7e-34	-5.3	5.2	2.2e-07	-0.41	0.57	0.43	FALSE
18	GTEx	Testis	RP11-375N15.2	0.12	0.01	enet	11	0.03	1.1e-02	-4.3	-5.8	8.8e-09	0.53	0.18	0.22	FALSE
19	GTEx	Thyroid	AC087269.1	0.15	0.05	lasso	2	0.07	5.1e-06	-5.1	5.7	1.1e-08	-0.44	0.66	0.30	FALSE
20	GTEx	Thyroid	SGK223	0.19	0.35	enet	16	0.36	1.1e-28	-5.0	5.3	9.0e-08	-0.76	0.46	0.54	FALSE
21	GTEx	Thyroid	CLDN23	0.14	0.03	lasso	2	0.03	1.1e-03	-5.1	5.8	7.2e-09	-0.44	0.44	0.26	FALSE
22	NTR	Blood	MFHAS1	0.02	0.01	blup	759	0.01	2.9e-04	-5.6	-6.0	1.6e-09	0.70	0.12	0.87	FALSE
23	NTR	Blood	MSRA	0.02	0.01	blup	833	0.01	2.3e-05	-5.2	5.6	1.7e-08	-0.78	0.05	0.95	FALSE
24	The Cancer Genome Atlas	Lung Adenocarcinoma	ERI1	0.06	0.04	blup	72	0.04	1.5e-05	-5.5	5.7	1.4e-08	-0.60	0.14	0.84	FALSE
25	The Cancer Genome Atlas	Thyroid Carcinoma	SGK223	0.16	0.20	enet	14	0.22	6.1e-21	4.6	5.1	2.9e-07	-0.69	0.08	0.90	FALSE