Best TWAS P=5.84e-08 · Best GWAS P=2.09e-08 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | USP36 | 0.14 | 0.13 | lasso | 3 | 0.13 | 1.7e-15 | 5.1 | -5.4 | 7.5e-08 | -0.94 | 0.02 | 0.98 | FALSE |
| 2 | GTEx | Brain Nucleus accumbens basal ganglia | USP36 | 0.36 | 0.23 | lasso | 5 | 0.20 | 4.8e-06 | 5.5 | -5.4 | 5.8e-08 | -0.97 | 0.02 | 0.96 | TRUE |
| 3 | GTEx | Esophagus Mucosa | USP36 | 0.11 | 0.04 | enet | 13 | 0.06 | 1.1e-04 | 5.5 | -5.2 | 2.1e-07 | -0.87 | 0.03 | 0.96 | FALSE |
| 4 | The Cancer Genome Atlas | Brain Lower Grade Glioma | USP36 | 0.04 | 0.00 | blup | 57 | 0.01 | 2.9e-02 | 5.5 | -5.3 | 1.4e-07 | -0.81 | 0.01 | 0.55 | FALSE |