TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Diastolic blood pressure, automated reading
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chr17:76,087,754-77,462,467
Best TWAS P=5.84e-08 · Best GWAS P=2.09e-08 conditioned to 1
76.2M
76.4M
76.6M
76.8M
77M
77.2M
77.4M
0
2
4
6
8
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
GTEx
Brain Nucleus accumbens basal ganglia
USP36
0.36
0.23
lasso
5
0.20
4.8e-06
5.5
-5.4
5.8e-08
-0.97
0.02
0.96
TRUE
1
CommonMind
Brain Pre-frontal Cortex
USP36
0.14
0.13
lasso
3
0.13
1.7e-15
5.1
-5.4
7.5e-08
-0.94
0.02
0.98
FALSE
4
The Cancer Genome Atlas
Brain Lower Grade Glioma
USP36
0.04
0.00
blup
57
0.01
2.9e-02
5.5
-5.3
1.4e-07
-0.81
0.01
0.55
FALSE
3
GTEx
Esophagus Mucosa
USP36
0.11
0.04
enet
13
0.06
1.1e-04
5.5
-5.2
2.1e-07
-0.87
0.03
0.96
FALSE