[Hub]/) : Traits : Diastolic blood pressure, automated reading : ← →

chr2:171,867,383-173,555,880

Best TWAS P=5.75e-09 · Best GWAS P=5.35e-09 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous DYNC1I2 0.13 0.11 enet 13 0.11 4.1e-09 -5.7 5.8 5.8e-09 -0.96 0.03 0.97 TRUE
2 GTEx Artery Aorta SLC25A12 0.13 0.03 lasso 16 0.01 1.2e-01 -5.3 -5.5 4.0e-08 0.97 0.03 0.94 FALSE
3 GTEx Artery Tibial DYNC1I2 0.10 0.06 enet 17 0.06 2.2e-05 -5.7 5.7 1.2e-08 -0.92 0.03 0.97 FALSE
4 GTEx Artery Tibial SLC25A12 0.11 0.09 lasso 8 0.06 8.4e-06 -5.2 -5.4 8.0e-08 0.97 0.03 0.97 FALSE
5 GTEx Brain Cerebellar Hemisphere DYNC1I2 0.32 0.24 lasso 7 0.26 2.0e-07 -5.5 5.7 1.6e-08 -0.93 0.03 0.96 FALSE
6 GTEx Brain Cerebellum SLC25A12 0.24 0.22 lasso 7 0.17 1.3e-05 -5.6 -5.2 1.6e-07 0.96 0.03 0.97 FALSE
7 GTEx Cells Transformed fibroblasts DYNC1I2 0.12 0.14 lasso 3 0.14 1.4e-10 -5.5 5.6 2.3e-08 -0.98 0.03 0.97 FALSE
8 GTEx Muscle Skeletal DYNC1I2 0.11 0.12 lasso 2 0.12 6.5e-12 -5.7 5.6 1.9e-08 -0.99 0.03 0.97 FALSE
9 GTEx Skin Sun Exposed Lower leg DYNC1I2 0.11 0.16 lasso 1 0.15 8.9e-13 -5.5 5.5 2.9e-08 -0.98 0.03 0.97 FALSE
10 GTEx Testis DYNC1I2 0.13 0.02 lasso 4 0.01 1.1e-01 -5.6 5.7 1.4e-08 -0.98 0.03 0.83 FALSE
11 ROSMAP Brain Pre-frontal Cortex AC068039.4 0.43 0.64 enet 35 0.65 1.6e-110 -5.5 -5.7 1.2e-08 0.99 0.03 0.97 FALSE
12 YFS Blood SLC25A12 0.09 0.15 lasso 7 0.15 1.3e-45 -5.5 -5.5 3.6e-08 0.98 0.03 0.97 FALSE
13 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma DYNC1I2 0.05 0.06 lasso 4 0.05 6.3e-06 -5.4 5.4 7.2e-08 -0.96 0.01 0.99 FALSE