TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Diastolic blood pressure, automated reading
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chr2:158,332,890-160,006,143
Best TWAS P=2.45e-10 · Best GWAS P=8.2e-12 conditioned to 0.00992
158.4M
158.6M
158.8M
159M
159.2M
159.4M
159.6M
159.8M
160M
0
2
4
6
8
10
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
ROSMAP
Brain Pre-frontal Cortex
CCDC148
0.17
0.08
lasso
7
0.07
1.0e-09
-6.5
-6.3
2.4e-10
0.92
0.02
0.98
TRUE
2
The Cancer Genome Atlas
Lung Squamous Cell Carcinoma
PKP4
0.06
0.00
blup
160
0.02
3.5e-03
2.9
-5.3
1.4e-07
0.68
0.02
0.37
FALSE