Best TWAS P=2.45e-10 · Best GWAS P=8.2e-12 conditioned to 0.00992
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | ROSMAP | Brain Pre-frontal Cortex | CCDC148 | 0.17 | 0.08 | lasso | 7 | 0.07 | 1.0e-09 | -6.5 | -6.3 | 2.4e-10 | 0.92 | 0.02 | 0.98 | TRUE |
| 2 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | PKP4 | 0.06 | 0.00 | blup | 160 | 0.02 | 3.5e-03 | 2.9 | -5.3 | 1.4e-07 | 0.68 | 0.02 | 0.37 | FALSE |