Best TWAS P=3.73e-12 · Best GWAS P=1.69e-11 conditioned to 0.218
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Caudate basal ganglia | FLNB | 0.17 | 0.10 | lasso | 12 | 0.12 | 0.00023 | -6.7 | 6.9 | 3.7e-12 | -0.89 | 0.02 | 0.94 | TRUE |
| 2 | GTEx | Brain Caudate basal ganglia | FLNB-AS1 | 0.17 | 0.04 | lasso | 7 | 0.10 | 0.00087 | 3.6 | 5.9 | 3.2e-09 | -0.69 | 0.06 | 0.81 | FALSE |
| 3 | GTEx | Brain Cerebellum | FLNB | 0.38 | 0.01 | enet | 24 | 0.09 | 0.00103 | -5.7 | -5.7 | 1.4e-08 | 0.52 | 0.06 | 0.44 | FALSE |