TWAS
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About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Diastolic blood pressure, automated reading
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chr3:57,294,295-58,854,266
Best TWAS P=3.73e-12 · Best GWAS P=1.69e-11 conditioned to 0.218
57.4M
57.6M
57.8M
58M
58.2M
58.4M
58.6M
58.8M
0
2
4
6
8
10
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Brain Caudate basal ganglia
FLNB
0.17
0.10
lasso
12
0.12
0.00023
-6.7
6.9
3.7e-12
-0.89
0.02
0.94
TRUE
2
GTEx
Brain Caudate basal ganglia
FLNB-AS1
0.17
0.04
lasso
7
0.10
0.00087
3.6
5.9
3.2e-09
-0.69
0.06
0.81
FALSE
3
GTEx
Brain Cerebellum
FLNB
0.38
0.01
enet
24
0.09
0.00103
-5.7
-5.7
1.4e-08
0.52
0.06
0.44
FALSE