Hub : Genes

FLNB

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.0480 0.0190 4.4e-04 0.030 0.021 0.021 0.024 0.047 1.4e-04 1.1e-03 1.2e-03 5.9e-04 2.0e-06
2 GTEx Artery Tibial 0.2504 0.0661 2.3e-06 0.034 NA 0.100 NA 0.072 1.0e-03 NA 3.0e-08 NA 2.7e-06
3 GTEx Brain Caudate basal ganglia 0.1730 0.0690 6.0e-03 0.102 NA 0.091 NA 0.122 7.4e-04 NA 1.4e-03 NA 2.3e-04
4 GTEx Brain Cerebellum 0.3810 0.1570 9.8e-03 0.010 NA 0.094 NA 0.050 1.6e-01 NA 1.0e-03 NA 1.4e-02
5 GTEx Nerve Tibial 0.1629 0.0484 5.9e-06 0.112 NA 0.039 NA 0.087 2.7e-08 NA 9.0e-04 NA 9.2e-07
6 GTEx Thyroid 0.1000 0.0350 4.8e-04 0.078 NA 0.071 NA 0.079 1.3e-06 NA 4.4e-06 NA 1.1e-06
7 ROSMAP Brain Pre-frontal Cortex 0.0744 0.0241 5.1e-06 0.060 0.038 0.057 0.060 0.055 3.6e-08 1.0e-05 7.4e-08 3.4e-08 1.4e-07
8 YFS Blood 0.2039 0.0388 0.0e+00 0.064 0.108 0.122 0.119 0.130 4.0e-20 1.5e-33 9.8e-38 1.1e-36 3.4e-40
9 TCGA Prostate Adenocarcinoma 0.0381 0.0168 8.0e-04 0.027 0.025 0.031 NA 0.030 7.2e-04 1.0e-03 3.0e-04 NA 3.9e-04

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bipolar Disorder (2018) 1.0 1.5 4.5 1.0 -0.5 -0.3 1.1 1.6 1.6 2.1 1.1 -0.4
Bipolar Disorder or Schizophrenia 0.8 1.9 6.5 0.4 0.9 0.3 1.2 1.7 2.0 2.5 0.9 0.6
Depressed Affect (Nagel 2018) 0.5 1.1 6.3 -0.6 2.5 -0.8 1.0 0.1 0.3 -0.6 1.0 -0.5
Depression (Nagel 2018) 1.8 2.8 9.7 -1.1 3.1 -2.1 1.8 1.2 0.2 0.3 2.1 0.6
Intelligence (Savage-Jansen 2018) 0.6 1.7 4.5 2.1 -0.3 1.9 -0.5 0.6 0.3 0.2 -2.1 -1.4
Neuroticism (Nagel 2018) 0.3 0.8 4.2 -0.4 2.0 -1.0 0.6 0.0 -0.2 -0.7 0.6 -0.7
Schizophrenia (2018) 0.5 1.0 2.6 -0.2 1.6 0.6 0.4 0.8 1.3 1.5 0.2 1.1
Schizophrenia vs Biploar Disorder 0.3 0.4 2.9 -0.0 1.7 0.6 0.7 0.1 0.4 -0.1 0.0 0.3
Worry (Nagel 2018) 0.4 0.9 3.3 -1.0 1.8 -0.2 0.5 0.2 0.3 -0.3 1.0 1.4
Alzheimer’s Disease (in mother) 1.0 1.1 5.1 -1.1 -0.0 -2.3 0.4 -0.9 -0.9 -1.3 0.6 0.2
Alzheimer’s Disease (in father) 0.4 0.4 1.6 -0.1 0.5 -1.3 1.2 -0.1 0.3 -0.5 0.4 -0.1
Alzheimer’s Disease (including proxy) 1.4 2.1 9.5 -1.2 0.5 -3.1 1.7 -0.9 -0.6 -1.4 1.0 -0.0
Crohns Disease (2017) 0.2 0.4 1.3 1.0 -1.1 0.2 -0.4 0.4 -0.1 1.1 -0.1 -0.1
Irritable Bowel Disease (IBD) 0.6 1.5 4.1 2.0 -0.9 -1.5 0.9 1.1 0.5 1.0 0.8 -1.7
Ulcerative Colitis (UC) 1.3 2.4 5.1 2.1 -0.3 -2.2 1.6 1.3 0.8 0.6 1.1 -2.3
Major Depression (MDD) 1.5 1.8 5.8 -1.4 0.5 -2.4 1.9 0.2 -0.4 -0.6 1.9 -0.1
Reaction Time 0.6 1.2 3.0 0.9 -0.8 1.4 -1.0 1.2 -0.7 1.7 -1.0 -0.6
Verbal and Numeric Reasoning (VNR) 0.3 0.7 2.2 1.3 -0.1 1.2 -0.4 0.5 0.1 0.3 -1.5 -0.6
Breast Cancer 0.4 1.0 4.1 0.8 -1.0 0.7 -0.2 -0.1 1.3 0.4 -2.0 -1.0
Ovarian Cancer 1.0 1.3 3.7 0.8 -1.3 0.7 -1.9 -0.7 -0.2 -1.1 -1.1 -1.6
Prostate Cancer 1.0 1.4 4.2 1.2 0.2 1.4 -2.0 -0.0 0.5 0.7 -1.9 -0.3
Age at First Birth 0.4 0.5 1.6 -0.5 1.2 0.1 0.8 0.2 0.9 0.1 -0.2 1.3
Bipolar Disorder (2011) 0.6 0.6 3.1 0.5 -0.5 -1.1 1.8 0.1 0.0 -0.1 0.1 -0.5
Body Mass Index (BMI) (2010) 0.5 0.7 2.4 0.5 1.0 1.3 -0.3 1.0 0.3 1.5 -0.3 0.0
Coronary Artery Disease (CAD) 2.1 2.5 12.2 0.4 -0.7 1.8 -3.5 -1.8 -1.3 -0.5 -0.7 -0.4
Crohns Disease (2012) 0.7 1.1 4.3 1.0 0.0 -0.1 -1.1 1.2 1.0 2.1 0.5 0.7
Mean Putamen Volume 0.5 0.5 2.8 0.7 -0.0 0.1 -0.4 1.7 0.9 0.7 0.3 0.0
Fasting Glucose 1.3 1.6 4.5 1.4 -1.4 0.8 -1.5 1.2 1.2 2.1 0.3 0.0
HbA1C 0.4 0.5 1.7 -0.6 -0.3 -0.1 -0.2 0.8 1.0 1.3 0.7 -0.2
HDL Cholesterol 0.3 0.5 2.3 1.0 -0.6 -0.6 -0.1 0.1 0.2 0.1 -0.1 -1.5
LDL Cholesterol 0.3 0.4 1.0 -0.2 -0.5 0.5 0.6 -1.0 0.4 0.5 -0.6 1.0
Lupus 3.0 4.6 17.5 -3.5 2.4 -0.4 0.9 -0.4 0.3 -1.4 1.8 4.2
Neuroticism (2016) 1.0 1.4 4.1 0.5 1.9 -0.9 2.0 0.8 1.6 0.5 0.3 -0.9
Primary Biliary Cirrhosis 0.7 1.0 3.1 -1.5 0.5 -0.4 -1.0 -0.6 1.3 0.3 -0.2 1.8
Rheumatoid Arthritis 0.8 1.1 2.5 -1.6 1.6 0.1 -1.6 -0.6 -0.5 -0.6 0.7 1.2
Schizophrenia (2014) 0.8 1.7 5.2 -0.3 1.8 0.5 0.9 1.1 2.3 1.6 0.4 1.3
Triglycerides 0.2 0.3 1.4 -0.5 -0.0 -0.5 0.7 0.0 -0.1 0.7 0.2 1.2
Type 2 Diabetes (T2D) (2012) 0.7 0.8 2.6 0.2 0.9 -1.6 1.0 0.0 1.1 0.4 1.2 -0.0
Ulcerative Colitis 1.2 1.8 5.9 1.2 1.3 -2.4 1.3 1.0 0.7 0.3 1.8 -0.8
Blood Eosinophil Count 0.2 1.7 4.9 -2.2 0.4 -1.8 0.2 -1.7 0.1 -1.8 0.5 1.0
Blood Platelet Count 1.9 22.5 52.6 -7.2 3.6 -4.5 2.6 -4.7 -3.3 -5.6 4.2 5.4
Blood Red Count 1.7 16.5 37.8 -5.0 5.0 -2.4 4.4 2.1 2.0 1.3 5.0 6.2
Blood White Count 1.1 8.3 37.0 -2.0 1.0 -6.1 4.2 -1.5 1.5 -2.5 1.9 0.5
Heel T-Score 1.3 10.7 33.2 1.0 2.6 5.8 -1.2 4.3 1.4 4.9 0.3 3.0
BMI 0.2 1.3 4.5 2.0 0.2 0.6 -0.5 0.2 -0.8 0.9 -0.9 -2.1
Height 0.3 5.6 29.6 -0.2 2.4 2.7 2.2 -0.2 5.4 -0.6 -1.3 1.0
Waist Hip Ratio (WHR) 1.7 7.5 32.5 -4.3 -0.1 -2.2 0.9 -2.4 1.7 -1.5 0.5 5.7
Systolic Blood Pressure 0.4 2.0 9.1 0.3 -1.6 1.8 -3.0 -1.0 0.3 -0.2 -1.4 -0.1
Smoking Status 0.6 1.4 5.2 -1.1 2.3 -0.5 1.6 -0.4 0.3 -1.0 1.2 0.8
Allergy or Eczema 0.5 1.2 3.7 1.1 -0.3 1.9 -1.1 -0.6 0.7 -0.1 -1.9 -0.5
Cardiovascular Disease 0.2 0.7 2.7 -0.3 -0.4 1.3 -1.6 -0.7 0.1 0.2 0.2 0.9
Hypothyroidism (self reported) 1.0 2.3 10.5 -1.8 1.1 1.4 -1.6 -0.6 -0.7 -0.6 0.4 3.2
Respiratory disease 0.6 1.2 2.9 1.7 -1.2 0.2 0.2 -0.9 -0.5 -0.7 -1.4 -1.7
Type 2 Diabetes (T2D) (2018) 0.8 1.6 7.8 -1.1 0.3 -2.8 0.6 -0.7 -0.5 -0.2 1.7 1.1
Lung FEV1/FVC ratio 1.6 8.0 20.7 1.6 -3.0 3.5 -2.8 2.3 2.8 4.5 -2.0 1.4
Lung FVC 1.2 6.3 24.9 2.0 -2.1 3.4 -5.0 1.3 -1.9 1.2 -1.4 -1.8
Neuroticism 0.2 0.4 1.7 -0.2 1.3 -0.5 1.0 -0.1 0.6 -0.6 -0.2 -0.5
Chronotype (morning person) 0.2 0.5 1.5 1.0 -0.7 0.3 0.4 0.7 0.3 0.8 -1.2 -0.2
Hair Pigment 0.1 1.5 5.7 -2.4 -0.1 -0.8 -0.5 -0.8 -1.6 -0.2 0.8 1.8
Tanning 0.0 0.3 1.6 -0.2 0.1 1.1 0.1 0.1 -0.3 -0.4 -1.3 -0.3
Hand grip strength (left) 0.6 1.5 5.2 -0.2 -0.6 2.3 -1.3 -0.2 1.1 -0.4 -1.7 1.4
Number of treatments/medications taken 0.7 1.2 3.9 -0.3 0.5 -1.8 -0.3 -0.6 -1.2 -0.7 2.0 -1.0
Average weekly spirits intake 0.3 0.4 1.0 0.1 -0.2 0.8 -0.7 -0.9 -1.0 -0.4 -0.4 0.0
Sensitivity / hurt feelings 0.8 1.3 3.5 1.1 -0.7 1.0 -1.1 -1.2 -0.7 -0.6 -1.6 -1.9
Frequency of depressed mood in last 2 weeks 1.2 1.7 7.3 -0.3 2.7 -1.6 1.4 1.2 0.5 0.4 1.5 -0.1
Hearing difficulty/problems: Yes 1.4 2.1 5.4 0.2 2.3 1.1 1.2 1.7 2.0 1.5 1.1 -0.2
Relative age of first facial hair 0.4 0.9 2.5 -1.0 -0.2 -0.7 -0.5 -1.4 -1.6 -1.2 0.2 0.1
Other serious medical condition/disability diagnosed by doctor 0.3 0.4 0.9 1.0 0.1 0.0 -0.1 0.5 -0.3 0.7 0.7 -1.0
Ever used hormone-replacement therapy (HRT) 0.9 1.1 3.9 -0.2 1.7 -2.0 1.1 -0.1 -0.1 -1.1 0.8 0.4
Ever had hysterectomy (womb removed) 1.4 1.6 4.7 -1.2 -0.8 0.9 -0.9 -2.2 -1.7 -1.6 -0.6 0.6
Systolic blood pressure, automated reading 0.5 1.6 6.6 0.2 -0.6 1.4 -2.6 -1.6 -0.6 -0.9 -0.2 -1.3
Eye problems/disorders: Diabetes related eye disease 0.8 0.8 1.7 1.3 -0.9 -0.6 0.2 1.3 0.9 1.3 0.5 -0.6
Angina 0.4 0.5 1.8 -0.3 -1.1 -0.6 -0.9 0.0 -1.3 0.0 0.1 -0.0
Medication for hormone replacement therapy 1.3 1.4 4.8 -0.8 2.2 -0.2 0.8 0.8 1.5 0.9 0.1 1.8
Vitamin and mineral supplements 0.1 0.2 0.6 0.1 -0.2 0.1 0.2 0.5 0.8 -0.2 -0.6 0.3
Supplements: Zinc 1.2 1.3 3.8 -0.5 1.4 -1.9 1.6 0.3 0.6 0.8 1.5 -0.3
Medication: Co-codamol 0.4 0.4 1.0 0.2 0.9 0.4 -0.9 0.8 0.7 1.0 -0.2 0.1
Medication: Metformin 1.0 1.4 3.8 0.3 1.2 -0.5 0.5 1.9 0.7 1.8 1.8 0.2
Diabetes (father) 1.3 1.6 3.1 -1.3 0.8 -1.4 0.3 -1.1 -1.7 -1.4 1.8 0.8
Diabetes (mother) 1.4 1.8 4.7 0.6 0.1 -1.8 1.3 1.3 1.6 1.3 2.2 0.7
Severe depression (siblings) 2.0 2.2 5.9 0.3 1.6 -0.0 1.1 2.4 1.9 1.9 1.6 0.5
Pack years adult smoking proportion 1.4 2.1 6.2 -1.2 2.1 1.6 -1.6 -0.9 0.7 -0.4 0.2 2.5
Impedance of leg (right) 1.4 6.8 21.1 -4.2 0.4 -2.2 -0.4 -3.2 -0.2 -2.6 -0.1 4.6
Leg fat-free mass (left) 1.0 5.4 13.0 3.3 0.8 3.6 0.9 2.1 2.4 2.1 -1.6 -2.4
Trunk fat percentage 0.3 1.2 3.9 1.5 1.1 0.4 0.8 -0.2 0.9 0.0 -1.1 -2.0
Hand grip strength (right) 1.2 3.2 8.6 0.1 -1.9 2.9 -2.0 -1.4 1.0 -0.9 -2.8 0.8
Townsend deprivation index at recruitment 2.5 3.5 7.3 -0.4 2.7 -0.8 2.6 2.1 2.2 1.8 1.6 1.2
Current tobacco smoking 0.4 0.7 2.5 -0.6 1.6 0.1 0.2 -0.4 0.3 -0.5 0.4 1.6
Average weekly fortified wine intake 0.3 0.4 1.4 0.2 1.2 0.9 -0.4 0.5 0.6 0.2 -0.0 0.5
Maternal smoking around birth 0.8 1.1 5.8 -1.2 2.4 0.3 0.8 0.2 0.1 -0.0 1.4 0.4
Fed-up feelings 0.6 1.0 6.1 -0.9 2.5 -0.8 0.2 0.3 -0.4 -0.4 0.8 0.9
Frequency of unenthusiasm / disinterest in last 2 weeks 1.5 2.0 5.4 -0.1 2.3 -1.3 1.3 2.0 1.1 1.2 1.7 -0.1
Relative age voice broke 0.8 1.3 2.9 -1.6 0.5 -0.7 0.4 -1.7 -1.6 -1.2 1.0 0.4
Taking other prescription medications 0.6 0.9 3.7 -0.4 1.3 -1.9 -0.2 -0.1 -0.7 -0.7 1.3 0.3
Age when periods started (menarche) 1.2 2.9 7.8 0.8 2.4 1.3 1.2 2.8 1.9 2.2 -0.1 0.5
Bilateral oophorectomy (both ovaries removed) 0.5 0.6 2.0 1.1 -0.6 0.3 -0.6 -0.5 0.4 -0.4 -1.4 -0.9
Heel bone mineral density (BMD) T-score, automated (left) 1.2 2.6 9.2 -0.5 1.6 1.8 -0.3 1.2 1.8 1.9 0.2 3.0
Tinnitus: Yes, but not now, but have in the past 1.9 2.0 8.7 -2.9 0.6 -1.2 0.1 -1.0 -0.9 -1.3 1.6 1.3
Qualifications: CSEs or equivalent 1.2 1.6 2.9 -1.4 1.7 -1.3 1.4 -0.3 1.1 -0.7 1.3 1.5
Serious illness, injury or assault to yourself 0.4 0.5 1.8 -0.5 0.4 -0.9 -0.7 0.1 -0.7 -0.2 1.3 0.4
High blood pressure 0.4 1.1 4.8 1.0 -0.9 2.2 -0.7 0.6 1.2 0.6 -0.4 -0.8
Hayfever, allergic rhinitis or eczema 0.5 1.0 3.5 0.6 -0.0 1.9 -1.3 -0.7 0.7 0.1 -1.7 0.1
Multivitamins +/- minerals 0.8 1.0 2.8 0.9 0.4 0.2 0.3 1.6 1.2 1.7 0.7 -0.7
Stomach or abdominal pain in last month 3.0 3.7 10.0 -2.6 1.8 -1.9 2.4 0.1 -1.0 -0.4 3.2 1.5
Supplements: Glucosamine 1.3 1.7 3.3 0.1 -0.5 -0.5 -1.4 -1.8 -1.7 -1.6 -1.8 -1.1
Diverticular disease/diverticulitis (self-reported) 3.3 4.0 6.3 0.1 2.1 -2.5 2.5 2.2 2.0 1.6 2.5 0.7
Medication: Atenolol 0.7 0.9 1.5 -0.8 1.2 -0.5 -1.0 -0.6 -1.0 -0.4 1.2 1.2
Medication: Levothyroxine sodium 1.0 1.7 4.2 -1.9 1.4 0.5 -1.0 0.0 -1.5 -1.0 0.8 2.0
Sitting height 0.9 6.0 27.8 1.2 0.5 5.3 -2.4 -1.6 -0.6 -1.4 -3.8 0.0
Chronic bronchitis/emphysema (father) 2.0 2.4 6.2 -0.0 2.0 -0.6 1.4 2.4 1.2 1.3 2.5 0.5
High blood pressure (mother) 2.2 3.2 15.8 1.6 -1.2 4.0 -0.4 0.4 1.1 1.9 -1.6 0.8
Body mass index (BMI) 0.4 1.7 6.4 2.2 0.3 1.0 0.3 1.0 0.1 1.3 -0.3 -2.5
Impedance of leg (left) 1.4 6.7 19.6 -4.3 0.8 -2.5 -0.3 -3.0 -0.1 -2.5 -0.0 4.4
Leg predicted mass (left) 1.0 5.4 13.0 3.4 0.8 3.6 1.0 2.2 2.4 2.1 -1.5 -2.4
Trunk fat mass 0.3 1.4 3.1 1.6 1.4 1.1 0.9 0.1 1.3 0.4 -1.0 -1.8
Waist circumference 0.1 0.3 0.9 -0.3 1.0 -0.2 0.7 -0.7 0.7 -0.2 -0.0 0.4
Number of incorrect matches in round 0.9 1.5 5.8 -0.5 0.1 -2.2 0.9 0.6 -0.8 -0.6 2.4 -0.7
Past tobacco smoking 0.9 1.7 4.3 1.2 -0.3 2.1 -1.6 1.1 1.2 1.4 -1.6 0.1
Alcohol usually taken with meals 2.1 3.3 7.9 0.2 -2.8 1.7 -2.3 -1.8 -0.8 -1.1 -2.6 -1.5
Nervous feelings 0.8 1.5 6.3 -0.9 1.1 -2.5 1.6 -0.6 -0.7 -1.1 0.8 0.2
Frequency of tenseness / restlessness in last 2 weeks 1.4 2.1 5.8 0.8 1.8 -1.6 2.4 1.3 0.7 -0.1 1.8 -1.4
Hearing difficulty/problems with background noise 0.3 0.5 2.1 -0.3 1.5 0.7 0.5 -0.5 0.8 -0.3 -0.3 -0.4
Hair/balding pattern: Pattern 2 1.4 1.7 7.7 -2.8 0.4 -0.2 0.8 -0.8 -0.1 -1.5 0.9 1.8
Had menopause 0.8 1.0 3.1 0.9 -0.8 0.1 -1.3 -0.6 -1.8 -1.2 -0.3 -0.7
Had other major operations 0.7 0.9 2.3 1.2 0.1 -0.0 0.2 1.2 1.1 1.1 -0.4 -1.5
Forced vital capacity (FVC) 1.3 5.0 22.1 1.4 -0.6 4.7 -3.4 0.6 0.3 1.0 -2.8 -0.2
Heel bone mineral density (BMD) T-score, automated (right) 1.1 2.5 10.0 -0.7 1.9 1.5 -0.2 0.8 1.8 1.4 -0.2 3.2
Ever unenthusiastic/disinterested for a whole week 1.1 1.4 4.4 -1.1 1.7 -0.7 1.4 0.9 0.8 0.2 2.1 0.2
Qualifications: None of the above 0.9 2.0 3.3 -1.6 0.8 -1.5 0.7 -1.8 -1.6 -1.8 1.5 0.8
Financial difficulties in last 2 years 0.4 0.5 1.5 0.2 1.2 -0.6 0.9 0.3 0.8 -0.1 1.0 -0.3
Mouth/teeth dental problems 0.8 1.2 2.8 0.6 1.1 -0.9 0.1 1.4 1.2 1.7 1.0 0.9
Heart attack 0.8 1.1 5.1 0.4 -1.4 0.2 -2.3 0.0 -1.4 0.3 -0.4 0.2
Allergy 0.4 1.0 3.1 -0.8 0.8 -1.8 1.0 0.9 -0.6 0.1 1.5 0.6
Pain all over the body in last month 0.5 0.6 1.7 0.2 1.3 -1.2 0.3 0.5 0.7 0.1 1.0 -0.2
Diabetes (self-reported) 0.9 1.3 5.2 0.2 1.6 -1.4 0.6 1.1 0.1 0.9 2.3 0.2
Hayfever/allergic rhinitis (self-reported) 1.0 1.3 3.3 0.4 -1.2 0.6 -1.8 -1.4 -0.4 -1.0 -1.8 0.6
Medication: Ramipril 1.1 1.4 3.6 1.6 -1.0 0.8 -1.9 0.7 1.3 1.0 -1.2 0.0
Medication: Simvastatin 0.3 0.4 1.5 -0.3 -0.6 -1.2 -0.4 -0.9 0.6 -0.1 0.6 -0.0
Fluid intelligence score 0.1 0.3 1.4 -0.0 -0.5 0.6 0.2 -0.2 0.4 -0.1 -1.2 0.2
Illnesses of siblings 0.4 0.5 1.7 -0.7 -0.4 -0.9 -0.3 -0.4 -1.1 -1.3 -0.1 -0.2
Neuroticism score 0.5 1.0 3.5 0.4 1.7 -1.0 1.9 0.1 0.3 -0.2 0.7 -1.0
Weight 0.5 2.5 5.5 2.1 1.2 2.3 0.7 1.0 1.8 1.3 -1.1 -1.7
Impedance of arm (right) 0.6 2.8 6.8 -2.6 0.8 -1.0 -0.0 -2.1 0.9 -2.1 -1.1 2.4
Arm fat percentage (right) 0.2 0.9 4.9 1.3 0.8 0.2 0.6 0.1 0.5 0.4 -0.7 -2.2
Trunk fat-free mass 0.6 3.2 9.9 1.9 0.7 3.2 0.7 2.0 2.1 2.1 -0.7 -0.8
Hip circumference 0.3 1.4 4.9 1.7 1.4 0.6 1.2 0.5 0.5 0.6 0.0 -2.2
Time employed in main current job 2.6 3.0 10.8 -1.1 -1.1 -1.8 -0.7 -1.8 -2.4 -3.3 0.6 -0.7
Alcohol intake versus 10 years previously 0.7 1.1 4.5 -0.4 2.1 0.1 0.5 0.9 0.1 1.0 1.4 1.0
Father’s age at death 1.2 1.6 4.8 -0.0 -1.8 -0.8 -1.0 -0.8 -2.2 -0.9 1.0 -1.6
Worrier / anxious feelings 0.2 0.4 1.6 0.2 1.3 0.6 0.3 0.7 0.6 0.7 0.6 0.0
Frequency of tiredness / lethargy in last 2 weeks 0.7 1.1 9.0 0.1 3.0 0.4 -0.3 0.7 0.4 -0.1 0.4 0.5
Falls in the last year 0.2 0.2 0.9 -0.5 1.0 -0.3 -0.2 -0.4 0.3 -0.2 -0.3 -0.4
Hair/balding pattern: Pattern 3 0.6 0.9 2.7 1.6 0.3 1.3 -0.8 0.8 0.7 0.2 -1.0 -0.6
Number of live births 2.3 3.2 5.9 -0.9 -1.6 -2.4 1.3 -1.5 -1.6 -1.9 2.0 -2.3
Forced expiratory volume in 1-second (FEV1) 2.0 6.7 22.8 1.5 -1.4 4.8 -3.8 1.2 1.1 2.4 -3.0 0.7
Pulse rate 0.5 0.8 3.6 -0.7 0.4 -1.9 0.1 0.9 -0.3 -0.8 1.1 0.2
Happiness 0.6 0.7 4.5 -0.6 2.1 -0.1 0.4 -0.5 -0.7 -0.4 0.4 0.1
Noisy workplace 0.6 0.8 1.9 -1.4 1.1 -0.7 0.2 -0.5 -1.0 -1.1 0.6 0.6
Qualifications: A levels/AS levels or equivalent 1.3 2.8 9.0 1.7 -3.0 1.0 0.2 0.1 0.7 1.0 -2.5 -2.2
Serious illness, injury or assault of a close relative in last 2 years 0.3 0.3 1.1 0.2 0.1 -0.2 0.5 0.5 0.7 -0.3 -0.6 -1.0
Mouth/teeth dental problems: Dentures 0.6 1.1 2.1 0.8 -1.4 1.4 -1.3 -0.8 -1.0 -0.4 -0.9 -0.7
Asthma 0.3 0.7 1.5 1.2 -0.5 -0.1 -0.1 -1.1 -0.2 -1.0 -1.1 -1.1
Medication: Ibuprofen (e.g. Nurofen) 0.9 1.1 2.2 1.0 0.3 0.8 1.1 1.1 1.5 1.2 -0.9 -1.1
Medication: Cholesterol lowering 0.9 1.4 5.4 1.3 -0.4 -0.5 0.4 1.3 1.5 2.3 1.2 -0.1
Depression (self-reported) 0.2 0.2 0.5 -0.5 0.6 -0.1 0.7 -0.2 -0.0 -0.7 0.6 0.1
Medication: Lansoprazole 0.8 1.0 3.3 -0.2 1.0 -1.8 1.0 0.7 -0.4 0.4 1.3 -0.8
Prospective memory result 0.3 0.3 1.9 -0.5 -0.1 -0.2 0.2 0.3 0.4 0.6 1.4 -0.1
Lung cancer (father) 1.3 1.6 4.9 0.3 -2.2 -1.4 0.8 -1.1 0.2 -1.2 -1.0 -1.7
Illnesses of mother 0.5 0.6 2.4 -1.2 0.4 -1.5 0.5 -0.2 -0.2 -0.9 -0.5 -0.2
Forced expiratory volume in 1-second (FEV1), Best measure 1.7 5.5 21.9 0.9 -0.3 4.7 -3.6 1.0 1.1 2.0 -2.6 0.9
Pulse wave Arterial Stiffness index 1.0 1.1 2.9 0.4 0.5 -0.7 0.5 1.7 1.7 1.7 0.3 0.4
Impedance of arm (left) 0.4 1.7 3.3 -1.8 0.8 -1.0 0.7 -1.6 1.1 -1.7 -0.7 1.6
Arm fat mass (right) 0.4 1.7 6.1 2.0 0.8 1.2 0.6 0.7 1.0 1.0 -0.9 -2.5
Trunk predicted mass 0.5 3.1 9.5 1.8 0.8 3.1 0.8 2.0 2.1 2.1 -0.6 -0.7
Standing height 0.4 4.3 15.4 0.2 1.9 3.6 0.8 0.2 3.9 0.2 -1.9 1.4
Length of working week for main job 0.8 0.9 3.7 -0.8 1.2 0.8 0.9 0.0 -0.2 0.1 0.7 1.9
Exposure to tobacco smoke at home 0.6 0.6 3.3 -0.3 -0.6 -1.8 0.2 -0.4 -0.3 -0.8 -1.0 0.4
Breastfed as a baby 0.2 0.3 0.8 -0.8 0.2 -0.7 0.9 -0.1 -0.4 -0.5 0.1 0.1
Tense / ‘highly strung’ 0.1 0.2 0.7 -0.4 0.9 -0.3 0.8 -0.0 0.1 -0.3 -0.0 0.6
Seen doctor (GP) for nerves, anxiety, tension or depression 0.9 1.4 3.3 -1.3 1.8 -1.3 1.5 0.6 1.0 0.2 1.1 1.1
Hair/balding pattern: Pattern 4 1.1 2.6 5.5 2.3 -2.4 1.4 -1.0 0.0 0.6 1.1 -2.1 -1.9
Birth weight of first child 0.4 0.7 1.9 0.7 -1.4 0.9 -0.8 0.5 0.9 0.6 -0.5 -0.8
Peak expiratory flow (PEF) 2.1 4.9 18.6 1.6 -0.1 4.3 -2.9 0.8 0.9 1.7 -3.2 0.9
Pulse wave reflection index 0.3 0.4 1.4 -0.0 0.4 0.5 -0.1 0.4 -0.0 1.1 -0.5 1.2
Ever highly irritable/argumentative for 2 days 1.1 1.3 6.0 -0.9 2.4 1.0 -0.2 0.9 0.5 0.4 1.4 0.8
Loud music exposure frequency 0.2 0.2 0.5 -0.7 0.3 0.5 0.2 -0.5 0.1 -0.4 -0.7 0.4
Qualifications: O levels/GCSEs or equivalent 1.9 3.0 6.6 1.7 -2.2 0.4 0.0 1.6 2.6 1.7 -1.5 -2.2
Mouth/teeth dental problems: Bleeding gums 0.7 0.9 3.1 -0.9 0.3 0.4 -0.1 -1.3 -1.2 -1.8 -0.9 0.0
Blood clot in the leg (DVT) 0.5 0.6 2.0 -0.3 -1.4 0.4 0.2 -0.9 -1.1 -0.9 -0.9 -0.3
Medication: Paracetamol 0.3 0.5 1.3 0.2 0.5 -0.7 0.5 0.5 -0.7 0.1 1.1 -1.0
Headache pain in last month 0.6 1.0 2.1 0.3 -0.2 -1.2 0.9 1.4 -0.1 0.9 1.4 -1.4
Medication for cholesterol, blood pressure or diabetes 0.7 1.2 2.9 -1.7 1.3 0.6 0.2 -1.3 -0.6 -1.3 -0.9 1.1
Glaucoma (self-reported) 0.7 0.8 3.4 -0.5 0.4 -0.6 1.0 1.2 0.1 0.8 1.8 0.3
Gout (self-reported) 1.1 1.5 6.1 2.5 -0.1 0.9 -0.3 1.1 0.5 1.2 -0.4 -1.9
Hypothyroidism/myxoedema (self-reported) 1.3 2.5 10.1 -1.8 2.2 1.3 -1.6 -0.1 -0.5 -0.4 0.4 3.2
Medication: Amlodipine 1.0 1.4 3.8 1.6 -1.5 0.8 -0.9 0.1 -0.3 -0.2 -1.6 -2.0
Medication: Ventolin 100micrograms inhaler 0.2 0.2 0.4 0.5 0.3 -0.1 0.5 0.5 0.7 0.3 -0.3 -0.6
Birth weight 0.3 0.7 2.8 0.1 -1.7 1.2 -1.1 -0.7 0.2 0.3 -0.2 -0.2
Chronic bronchitis/emphysema (mother) 0.6 0.7 3.3 0.9 0.7 1.8 0.4 0.5 0.9 0.6 -0.0 -0.2
High blood pressure (siblings) 0.8 1.2 3.2 1.2 -1.0 1.8 -0.6 -0.6 1.2 0.4 -1.4 -1.0
Forced vital capacity (FVC), Best measure 1.2 4.2 19.0 1.4 0.4 4.4 -2.9 0.9 1.0 1.4 -2.2 -0.1
Body fat percentage 0.2 0.8 2.9 1.0 1.1 0.2 0.7 -0.6 0.5 -0.2 -0.9 -1.7
Leg fat percentage (right) 0.1 0.3 1.0 -0.2 0.9 -0.5 0.5 -1.0 -0.1 -0.4 -0.3 -0.3
Arm fat-free mass (right) 0.6 3.1 8.1 2.3 0.8 2.8 1.0 1.8 2.0 1.9 -0.8 -1.1
Exposure to tobacco smoke outside home 0.2 0.2 1.0 -0.2 0.6 -0.1 0.6 0.5 -0.3 0.2 1.0 0.0
Comparative body size at age 10 0.2 0.5 1.8 -0.1 -0.9 0.3 -0.4 -0.7 -1.3 -0.4 -0.3 -1.1
Number of full brothers 2.2 2.7 7.0 -2.6 2.0 -1.0 0.2 -0.8 -0.8 -0.1 2.1 2.6
Worry too long after embarrassment 0.3 0.5 2.6 0.8 0.5 -1.6 0.7 -0.0 0.2 0.0 0.0 -0.9
Seen a psychiatrist for nerves, anxiety, tension or depression 1.1 1.4 3.7 -0.3 1.7 -0.4 1.2 1.1 1.9 0.9 0.2 1.4
Wheeze or whistling in the chest in last year 0.5 0.8 2.9 -0.2 0.6 -1.0 1.7 -0.5 0.5 -1.3 0.8 -0.4
Number of children fathered 0.6 0.6 1.5 0.0 0.4 0.5 -1.0 -1.2 -0.7 -1.1 -0.8 -0.7
Reason for reducing amount of alcohol drunk: Health precaution 0.2 0.3 0.7 0.3 -0.8 -0.1 0.6 0.7 0.7 0.4 -0.2 -0.6
Age at first live birth 0.5 0.9 2.6 -0.4 -0.7 -0.0 -0.6 -1.5 -0.7 -1.0 -1.6 0.7
Pulse wave peak to peak time 0.7 0.8 2.0 -0.3 -0.2 1.1 -0.4 -1.4 -1.1 -1.4 -0.6 -0.3
Health satisfaction 2.0 2.6 8.2 -1.1 2.1 -2.9 1.5 0.3 -0.4 -0.9 2.5 -0.7
Shortness of breath walking on level ground 1.1 1.3 2.7 -1.5 1.6 -1.4 0.7 -0.4 -0.4 -1.4 1.3 0.4
Qualifications: College or University degree 1.8 5.6 15.1 1.8 -2.9 3.5 -2.1 -0.8 1.4 1.2 -3.9 -1.5
Eye problems/disorders: None of the above 1.8 2.1 3.8 1.9 -1.7 1.2 -1.9 -0.0 0.0 0.8 -1.9 -1.6
Mouth/teeth dental problems: Loose teeth 1.3 1.5 3.8 -1.6 0.4 -0.7 -0.7 -1.6 -2.0 -1.8 0.5 0.4
Emphysema/chronic bronchitis 2.6 3.0 10.4 -3.2 1.7 -0.8 0.8 -1.1 -0.0 -1.4 1.1 2.7
Medication for pain relief, constipation, heartburn 1.0 1.7 5.8 -0.9 -1.3 0.6 -1.0 -1.2 -0.3 -0.9 -1.7 2.4
Neck or shoulder pain in last month 4.5 6.4 15.9 -0.3 4.0 -0.9 2.8 3.2 2.4 1.7 3.5 1.6
Medication: Blood pressure 0.8 1.4 3.6 1.7 -1.9 0.4 -1.7 0.7 -0.1 0.3 -0.6 -1.4
Angina (self-reported) 0.4 0.5 2.6 -0.4 -1.0 -0.8 -0.5 0.0 -1.6 -0.2 0.5 0.0
Migraine (self-reported) 0.7 0.9 2.4 0.4 1.6 -0.5 0.6 1.1 0.8 1.4 1.1 -0.2
Medication: Ibuprofen 0.8 0.9 2.8 0.6 0.2 1.0 0.5 1.0 1.7 1.7 -0.5 -0.2
Medication: Allopurinol 1.5 2.0 3.6 1.9 1.4 1.0 1.2 1.9 1.5 1.9 0.9 -0.2
Medication: Omeprazole 1.8 2.1 5.1 -1.3 2.0 -2.2 1.1 1.0 0.9 0.4 2.1 0.6
Medication: Seretide 50 evohaler 2.2 2.5 8.4 -1.6 1.2 -1.7 0.1 -1.9 -1.0 -2.9 1.7 0.0
Mean time to correctly identify matches 0.5 0.9 1.8 1.1 -0.9 0.4 -1.1 1.1 -1.0 1.4 0.2 -0.9
Heart disease (mother) 0.7 0.9 5.4 0.1 -0.3 1.3 -2.3 0.2 -0.4 0.7 0.4 0.4
Reproduciblity of spirometry measurement using ERS/ATS criteria 1.6 1.9 6.9 -1.5 2.6 -0.5 1.6 0.0 -0.6 -0.5 1.8 1.4
Whole body fat mass 0.3 1.1 3.3 1.4 1.2 1.1 0.8 -0.1 0.9 0.2 -0.9 -1.8
Leg fat mass (right) 0.2 0.7 1.2 1.1 1.0 1.0 0.5 -0.2 0.6 0.2 -1.0 -1.1
Arm predicted mass (right) 0.6 2.9 9.1 2.4 0.6 3.0 0.6 1.5 1.6 1.7 -1.0 -1.3
Pulse rate, automated reading 0.4 1.3 4.7 -1.0 1.9 -0.3 0.2 0.5 0.7 -1.2 2.2 0.6
Alcohol intake frequency. 1.1 2.7 10.5 -1.5 3.2 0.1 -0.3 0.8 1.0 0.7 0.6 2.9
Comparative height size at age 10 0.4 2.0 7.0 -1.0 1.4 0.7 0.5 0.4 2.6 0.2 -0.9 2.4
Number of full sisters 2.6 3.2 9.4 0.5 1.1 0.6 1.0 2.6 3.0 3.1 -0.2 0.5
Suffer from ‘nerves’ 1.2 1.9 5.5 0.5 1.5 -2.4 2.1 0.9 1.4 0.6 1.4 -0.0
Overall health rating 2.6 5.5 19.1 -1.7 4.4 -2.4 2.3 1.2 0.6 -0.2 3.3 2.1
Chest pain or discomfort 1.3 1.8 7.6 -1.4 0.8 -2.1 0.7 -0.2 -0.4 -0.4 2.8 1.0
Had major operations 1.6 1.9 6.5 0.1 -1.0 -1.0 2.5 1.1 1.1 0.3 2.1 -1.2
Age at last live birth 0.7 1.0 2.9 0.4 -1.7 0.7 -0.5 -1.5 0.1 -0.4 -1.6 -0.3
Family relationship satisfaction 0.5 0.6 1.8 -1.1 0.7 0.0 -0.2 -0.4 -1.4 -0.1 1.0 1.0
Leg pain on walking 0.3 0.4 1.5 0.4 -0.0 -0.0 1.2 0.8 -0.2 0.2 0.3 -1.1
Qualifications: NVQ or HND or HNC or equivalent 2.1 2.6 7.7 1.0 1.8 -0.5 1.6 2.8 2.1 1.8 1.0 0.4
Commuting to job workplace: Car/motor vehicle 0.5 0.6 1.6 -0.4 0.2 -0.9 -0.3 -1.3 0.5 -0.7 -1.1 0.7
Illness, injury, bereavement, stress in last 2 years 0.9 1.1 2.6 1.3 -0.9 1.4 0.1 0.9 1.6 1.4 -0.8 -0.1
Medication: Aspirin 0.5 0.7 1.8 1.0 0.1 -0.7 0.8 0.9 -0.4 0.3 1.1 -1.4
Supplements: Vitamin C 1.4 1.7 5.0 -0.9 -1.1 -0.9 -0.3 -2.2 -2.0 -1.8 -0.3 -0.4
Knee pain experienced in last month 0.8 1.3 3.1 1.5 1.8 1.5 -0.8 0.9 0.3 1.4 -0.2 -0.6
Hypertension (Self-reported) 0.3 0.9 3.8 1.0 -0.9 1.9 -0.8 0.2 0.6 0.2 -0.4 -1.0
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 2.3 2.7 5.5 -0.4 1.6 -1.3 2.3 2.0 1.3 1.8 2.3 0.2
Illnesses of father: Heart disease 0.7 1.0 4.0 -0.8 -2.0 -0.8 -0.1 0.3 -0.8 0.9 0.1 1.4
Illnesses of siblings: Diabetes 1.2 1.5 3.3 -1.8 1.5 -1.4 0.0 -0.1 -0.5 0.3 1.6 1.8
Smoking status: Previous 0.7 1.1 3.3 -0.5 -0.0 -1.8 1.6 -0.1 -0.8 -0.6 1.4 -0.9
Forced expiratory volume in 1-second (FEV1), predicted 0.9 2.0 4.9 -0.3 1.9 1.7 0.0 0.5 2.2 1.1 -0.4 2.2
Whole body fat-free mass 0.7 4.2 11.9 2.6 0.8 3.5 0.9 2.2 2.3 2.2 -1.0 -1.5
Leg fat-free mass (right) 1.1 6.1 13.6 3.6 0.8 3.7 0.9 2.4 2.6 2.3 -1.7 -2.7
Arm fat percentage (left) 0.3 1.3 6.7 1.6 0.7 0.2 0.9 0.2 0.5 0.5 -0.5 -2.6
Average weekly red wine intake 1.0 1.5 4.0 0.7 -1.4 1.7 -0.9 0.1 -0.4 0.7 -1.7 -2.0
Handedness (chirality/laterality): Left-handed 0.3 0.4 1.1 0.3 0.2 -0.8 0.8 1.0 0.5 0.6 0.7 0.4
Mood swings 0.5 0.8 2.4 -0.4 1.0 -0.8 1.6 -1.1 -0.5 -1.3 -0.1 -0.4
Loneliness, isolation 2.4 3.3 8.5 -0.8 2.9 -1.9 2.7 0.8 0.9 -0.1 2.8 0.7
Long-standing illness, disability or infirmity 1.4 2.1 13.0 0.1 3.6 -0.3 0.5 1.3 0.8 0.9 1.5 0.2
Ever had bowel cancer screening 1.8 2.1 4.8 0.4 1.8 -0.2 1.6 1.6 1.5 2.2 1.6 1.0
Diabetes diagnosed by doctor 0.8 1.3 5.5 -0.1 1.4 -1.8 0.5 0.4 -0.8 0.4 2.4 -0.1
Ever had stillbirth, spontaneous miscarriage or termination 0.6 0.6 1.5 -0.3 0.9 -0.0 1.0 1.0 0.5 1.0 -0.1 1.2
Friendships satisfaction 1.2 1.5 5.5 -1.5 2.3 1.0 0.2 -0.6 -0.1 0.0 0.9 1.7
Qualifications: nursing, teaching 1.7 2.6 6.8 2.0 -0.5 2.2 -0.4 2.0 1.7 2.6 -0.9 -0.6
Commuting to job workplace: Walk 0.6 0.6 1.4 -0.3 -1.2 1.1 -0.7 0.5 -1.1 0.9 -0.1 -0.2
Eye problems/disorders: Cataract 0.4 0.4 1.2 -1.0 0.1 -0.2 0.3 -1.1 0.4 -0.9 -0.6 0.3
Mouth/teeth dental problems: Mouth ulcers 0.1 0.1 0.5 -0.1 0.3 0.1 0.7 -0.1 -0.1 -0.1 0.0 -0.5
Medication for cholesterol 0.1 0.1 0.4 0.0 -0.6 0.1 0.2 -0.1 -0.3 -0.5 0.0 0.1
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.5 0.6 2.5 -0.3 -0.4 -0.3 0.2 -1.6 -0.3 -1.4 -0.4 -0.7
Back pain experienced in last month 1.4 2.0 13.0 -0.9 3.6 0.8 0.2 0.4 -0.6 0.1 0.6 1.6
Mineral and other dietary supplements 0.6 0.8 2.2 -0.6 0.7 -0.1 0.9 1.2 1.3 0.3 0.3 1.5
Breast cancer (self-reported) 1.7 2.0 5.3 -1.1 1.4 -1.6 -0.0 -0.7 -2.3 -1.1 2.2 0.7
Asthma (self-reported) 0.4 0.8 2.0 1.0 -0.6 0.1 -0.5 -1.4 -0.3 -1.1 -1.4 -0.7
Osteoporosis (self-reported) 0.7 0.8 4.2 -2.0 0.2 -0.6 0.8 -0.6 -0.3 -0.9 -0.2 0.9
Osteoarthritis (self-reported) 2.3 3.0 8.3 -0.0 2.9 -1.8 1.8 1.8 1.6 1.9 1.3 1.0
Medication: Aspirin 0.4 0.5 1.3 0.9 -0.1 -0.5 0.6 0.7 -0.6 0.1 1.1 -1.1
Medication: Gliclazide 1.7 1.9 4.9 -1.2 1.5 -2.0 1.0 1.2 -0.3 0.6 2.2 1.5
Illnesses of father: None of the above (group 1) 0.5 0.6 2.1 0.2 -0.4 -0.9 0.4 -0.8 -0.6 -1.2 -0.1 -1.4
Smoking status: Current 0.5 0.8 2.1 -0.9 1.5 -0.4 0.4 -0.8 -0.1 -0.9 0.5 1.4
Forced expiratory volume in 1-second (FEV1), predicted percentage 1.1 2.4 6.3 1.0 -1.9 2.2 -2.5 1.0 -0.3 1.5 -1.1 -0.8
Whole body water mass 0.8 4.4 12.3 2.7 0.8 3.5 0.8 2.2 2.4 2.2 -1.1 -1.5
Leg predicted mass (right) 1.2 6.2 13.3 3.6 0.8 3.6 0.9 2.4 2.6 2.3 -1.7 -2.8
Arm fat mass (left) 0.5 2.0 6.4 2.1 0.8 1.2 0.9 0.9 1.1 1.2 -0.8 -2.5
Number of self-reported non-cancer illnesses 0.1 0.2 0.8 0.7 0.2 0.0 -0.0 0.4 0.5 0.5 0.9 -0.3
Average weekly champagne plus white wine intake 2.5 3.4 13.7 1.9 -3.7 0.6 -1.3 -1.3 -0.2 -0.5 -2.3 -2.0
Miserableness 0.6 1.0 4.4 1.1 0.7 -0.7 1.1 0.7 0.5 -0.1 -0.7 -2.1
Guilty feelings 0.8 1.2 4.0 1.4 1.3 -1.2 0.7 0.6 0.9 0.6 -0.4 -2.0
Wears glasses or contact lenses 0.8 1.0 4.7 1.1 -0.7 -0.2 -1.1 0.3 0.5 0.1 0.7 -2.2
Ever taken oral contraceptive pill 0.4 0.5 1.0 -0.9 0.1 -0.9 0.1 -0.9 -0.8 -0.7 0.0 1.0
Hearing aid user 1.6 1.8 4.0 -1.9 2.0 -0.9 0.8 0.3 -0.1 0.2 1.9 1.9
Mother’s age at death 0.8 1.0 4.9 0.4 -1.2 -2.2 0.5 0.6 -0.3 0.1 0.4 -1.1
Financial situation satisfaction 0.2 0.3 1.4 0.8 0.0 -0.0 0.1 0.5 0.4 0.1 0.2 -1.2
Tinnitus: Yes, now most or all of the time 1.1 1.3 3.5 1.0 0.2 0.1 0.1 1.6 1.9 1.8 -1.0 0.7
Commuting to job workplace: Public transport 0.5 0.6 1.6 -0.4 -1.0 0.3 0.5 1.2 0.2 0.9 1.2 -0.0
Eye problems/disorders: Glaucoma 0.7 0.8 2.3 0.3 1.1 0.8 0.9 1.5 0.4 0.7 1.2 -0.2
Medication: Blood pressure 0.5 0.9 1.5 1.2 -1.1 0.9 -1.1 0.2 0.7 0.7 -1.1 -0.8
Pain type(s) experienced in last month: Hip pain 0.5 0.6 2.3 -0.4 0.2 1.5 -1.0 -0.9 -1.0 -0.7 0.1 -0.1
Supplements: Fish oil (including cod liver oil) 0.8 1.1 2.9 0.8 -1.1 0.9 -1.2 -1.1 -0.6 -0.2 -1.1 -1.7
High cholesterol (Self-reported) 0.5 1.0 2.3 1.4 -0.8 -0.6 0.5 -0.1 1.0 1.5 1.2 -0.8
Medication: Bendroflumethiazide 0.5 0.8 2.6 -0.3 -1.0 -0.5 -1.6 -0.8 -0.3 -1.3 -0.2 -0.9
Medication: Paracetamol 0.2 0.3 1.0 0.2 0.5 -0.2 -0.3 0.2 -0.7 0.5 1.0 -0.6
Medication: Lisinopril 0.9 1.1 3.9 -0.7 -0.3 -0.0 -2.0 -1.5 -1.0 -1.1 -1.0 -0.5
Medication: Atorvastatin 1.0 1.2 3.9 0.3 0.5 -0.3 0.4 1.5 -0.0 2.0 1.9 0.7
Illnesses of father: High blood pressure 0.6 0.8 2.9 -0.5 0.8 1.7 -0.8 0.3 0.6 0.4 -0.4 1.4
Alcohol drinker status: Never 1.4 1.6 6.8 0.5 -0.5 2.6 -1.9 0.1 1.0 0.7 -1.6 0.1
Ever smoked 0.7 1.2 3.2 -1.4 0.1 -1.8 0.6 -1.4 -1.0 -1.4 0.7 0.4
Basal metabolic rate 0.8 4.2 11.5 2.6 1.0 3.4 0.8 2.0 2.3 2.1 -1.3 -1.6
Leg fat percentage (left) 0.1 0.3 1.3 -0.1 1.1 -0.6 0.5 -0.8 -0.1 -0.1 -0.2 -0.5
Arm fat-free mass (left) 0.6 2.9 9.1 2.1 0.9 3.0 0.6 1.7 1.7 1.9 -0.8 -1.2
Number of operations (self-reported) 0.4 0.6 1.9 0.2 -0.1 -0.7 0.4 0.6 0.9 0.9 1.4 -1.1
Average weekly beer plus cider intake 1.8 2.7 5.9 -0.8 2.4 -0.7 2.3 1.3 0.9 1.5 1.6 2.0
Irritability 0.6 1.0 2.7 0.7 1.6 0.1 1.6 1.1 0.4 0.4 -0.0 -1.3
Risk taking 0.8 1.2 3.9 -0.5 0.9 2.0 0.1 0.3 0.5 1.6 0.8 1.3
Ever had prostate specific antigen (PSA) test 0.8 0.9 2.2 0.7 0.3 -1.4 0.0 0.7 -0.2 0.8 1.5 -1.4
Fractured/broken bones in last 5 years 1.2 1.6 5.0 -2.2 2.2 -0.0 0.3 -0.3 -0.5 -1.0 1.1 1.3
Age started oral contraceptive pill 0.9 1.1 4.2 0.3 0.2 -0.3 -1.2 -0.2 -2.0 -1.7 -0.1 -1.0
Diastolic blood pressure, automated reading 4.1 12.6 48.3 2.4 -2.2 6.9 -5.7 -0.8 0.9 0.8 -4.5 -0.9
Ever depressed for a whole week 0.6 0.8 2.6 -1.0 0.6 0.3 0.2 0.8 0.6 0.8 1.6 1.0
Unable to work because of sickness or disability 1.6 2.0 3.8 -1.9 1.9 -1.8 0.6 -0.2 -0.8 -0.6 1.9 1.5
Commuting to job workplace: Cycle 1.2 1.4 3.7 1.6 -1.1 -1.8 0.7 1.0 -0.3 0.2 0.2 -1.9
Myopia 0.4 0.6 1.2 1.1 -0.7 -0.0 -1.1 0.8 0.8 0.7 -0.1 -0.9
Vascular/heart problems diagnosed by doctor 0.5 1.2 3.9 -1.2 1.2 -2.0 1.1 -0.6 -1.1 -0.8 0.1 0.9
Cholesterol lowering medication 0.4 0.6 2.0 0.3 -0.1 -0.2 -1.4 -1.4 -0.8 -0.7 -0.2 -0.8
Medication: Omeprazole (e.g. Zanprol) 2.2 2.7 5.7 -0.8 1.8 -2.2 1.8 2.0 1.1 1.1 2.4 0.7
Pain experienced in last month 1.0 1.7 8.8 0.2 -3.0 0.6 -1.4 -1.3 0.1 -0.3 -1.5 0.3
Supplements: Calcium 1.4 1.5 4.8 -2.2 0.7 -1.6 1.7 -0.7 0.1 -0.6 1.3 0.4
Basal cell carcinoma (self-reported) 0.5 0.6 3.2 0.1 0.6 -0.4 1.8 0.2 0.6 0.1 0.7 -1.0
Heart attack/myocardial infarction (self-reported) 0.8 1.1 4.6 0.3 -1.4 -0.3 -2.2 -0.2 -1.6 0.1 -0.1 0.3
Deep venous thrombosis (DVT) (self-reported) 0.4 0.6 1.6 -0.1 -1.3 0.5 0.1 -0.7 -1.0 -0.7 -1.2 -0.2
Heart disease (siblings) 0.4 0.4 1.6 -0.2 0.8 0.8 0.5 -0.3 -0.5 0.1 0.8 1.3
Alcohol drinker status: Previous 1.2 1.4 2.7 -1.3 1.0 0.2 0.6 0.4 1.6 1.2 1.6 1.6
Pack years of smoking 1.1 1.6 4.3 -0.9 2.1 1.4 -1.6 -0.8 0.5 -0.5 0.1 1.8
Impedance of whole body 0.8 4.0 10.0 -3.2 0.8 -1.8 0.1 -2.5 0.7 -2.4 -0.5 3.1
Leg fat mass (left) 0.2 0.7 1.5 1.0 1.0 1.0 0.4 -0.2 0.5 0.3 -1.1 -1.2
Arm predicted mass (left) 0.5 2.5 8.0 2.1 0.7 2.8 0.3 1.5 1.6 1.7 -0.9 -1.2