Hub : Genes

FLNB

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0480	0.0190	4.4e-04	0.030	0.021	0.021	0.024	0.047	1.4e-04	1.1e-03	1.2e-03	5.9e-04	2.0e-06
2	GTEx	Artery Tibial	0.2504	0.0661	2.3e-06	0.034	NA	0.100	NA	0.072	1.0e-03	NA	3.0e-08	NA	2.7e-06
3	GTEx	Brain Caudate basal ganglia	0.1730	0.0690	6.0e-03	0.102	NA	0.091	NA	0.122	7.4e-04	NA	1.4e-03	NA	2.3e-04
4	GTEx	Brain Cerebellum	0.3810	0.1570	9.8e-03	0.010	NA	0.094	NA	0.050	1.6e-01	NA	1.0e-03	NA	1.4e-02
5	GTEx	Nerve Tibial	0.1629	0.0484	5.9e-06	0.112	NA	0.039	NA	0.087	2.7e-08	NA	9.0e-04	NA	9.2e-07
6	GTEx	Thyroid	0.1000	0.0350	4.8e-04	0.078	NA	0.071	NA	0.079	1.3e-06	NA	4.4e-06	NA	1.1e-06
7	ROSMAP	Brain Pre-frontal Cortex	0.0744	0.0241	5.1e-06	0.060	0.038	0.057	0.060	0.055	3.6e-08	1.0e-05	7.4e-08	3.4e-08	1.4e-07
8	YFS	Blood	0.2039	0.0388	0.0e+00	0.064	0.108	0.122	0.119	0.130	4.0e-20	1.5e-33	9.8e-38	1.1e-36	3.4e-40
9	TCGA	Prostate Adenocarcinoma	0.0381	0.0168	8.0e-04	0.027	0.025	0.031	NA	0.030	7.2e-04	1.0e-03	3.0e-04	NA	3.9e-04

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9
Bipolar Disorder (2018)	1.0	1.5	4.5	1.0	-0.5	-0.3	1.1	1.6	1.6	2.1	1.1	-0.4
Bipolar Disorder or Schizophrenia	0.8	1.9	6.5	0.4	0.9	0.3	1.2	1.7	2.0	2.5	0.9	0.6
Depressed Affect (Nagel 2018)	0.5	1.1	6.3	-0.6	2.5	-0.8	1.0	0.1	0.3	-0.6	1.0	-0.5
Depression (Nagel 2018)	1.8	2.8	9.7	-1.1	3.1	-2.1	1.8	1.2	0.2	0.3	2.1	0.6
Intelligence (Savage-Jansen 2018)	0.6	1.7	4.5	2.1	-0.3	1.9	-0.5	0.6	0.3	0.2	-2.1	-1.4
Neuroticism (Nagel 2018)	0.3	0.8	4.2	-0.4	2.0	-1.0	0.6	0.0	-0.2	-0.7	0.6	-0.7
Schizophrenia (2018)	0.5	1.0	2.6	-0.2	1.6	0.6	0.4	0.8	1.3	1.5	0.2	1.1
Schizophrenia vs Biploar Disorder	0.3	0.4	2.9	-0.0	1.7	0.6	0.7	0.1	0.4	-0.1	0.0	0.3
Worry (Nagel 2018)	0.4	0.9	3.3	-1.0	1.8	-0.2	0.5	0.2	0.3	-0.3	1.0	1.4
Alzheimer’s Disease (in mother)	1.0	1.1	5.1	-1.1	-0.0	-2.3	0.4	-0.9	-0.9	-1.3	0.6	0.2
Alzheimer’s Disease (in father)	0.4	0.4	1.6	-0.1	0.5	-1.3	1.2	-0.1	0.3	-0.5	0.4	-0.1
Alzheimer’s Disease (including proxy)	1.4	2.1	9.5	-1.2	0.5	-3.1	1.7	-0.9	-0.6	-1.4	1.0	-0.0
Crohns Disease (2017)	0.2	0.4	1.3	1.0	-1.1	0.2	-0.4	0.4	-0.1	1.1	-0.1	-0.1
Irritable Bowel Disease (IBD)	0.6	1.5	4.1	2.0	-0.9	-1.5	0.9	1.1	0.5	1.0	0.8	-1.7
Ulcerative Colitis (UC)	1.3	2.4	5.1	2.1	-0.3	-2.2	1.6	1.3	0.8	0.6	1.1	-2.3
Major Depression (MDD)	1.5	1.8	5.8	-1.4	0.5	-2.4	1.9	0.2	-0.4	-0.6	1.9	-0.1
Reaction Time	0.6	1.2	3.0	0.9	-0.8	1.4	-1.0	1.2	-0.7	1.7	-1.0	-0.6
Verbal and Numeric Reasoning (VNR)	0.3	0.7	2.2	1.3	-0.1	1.2	-0.4	0.5	0.1	0.3	-1.5	-0.6
Breast Cancer	0.4	1.0	4.1	0.8	-1.0	0.7	-0.2	-0.1	1.3	0.4	-2.0	-1.0
Ovarian Cancer	1.0	1.3	3.7	0.8	-1.3	0.7	-1.9	-0.7	-0.2	-1.1	-1.1	-1.6
Prostate Cancer	1.0	1.4	4.2	1.2	0.2	1.4	-2.0	-0.0	0.5	0.7	-1.9	-0.3
Age at First Birth	0.4	0.5	1.6	-0.5	1.2	0.1	0.8	0.2	0.9	0.1	-0.2	1.3
Bipolar Disorder (2011)	0.6	0.6	3.1	0.5	-0.5	-1.1	1.8	0.1	0.0	-0.1	0.1	-0.5
Body Mass Index (BMI) (2010)	0.5	0.7	2.4	0.5	1.0	1.3	-0.3	1.0	0.3	1.5	-0.3	0.0
Coronary Artery Disease (CAD)	2.1	2.5	12.2	0.4	-0.7	1.8	-3.5	-1.8	-1.3	-0.5	-0.7	-0.4
Crohns Disease (2012)	0.7	1.1	4.3	1.0	0.0	-0.1	-1.1	1.2	1.0	2.1	0.5	0.7
Mean Putamen Volume	0.5	0.5	2.8	0.7	-0.0	0.1	-0.4	1.7	0.9	0.7	0.3	0.0
Fasting Glucose	1.3	1.6	4.5	1.4	-1.4	0.8	-1.5	1.2	1.2	2.1	0.3	0.0
HbA1C	0.4	0.5	1.7	-0.6	-0.3	-0.1	-0.2	0.8	1.0	1.3	0.7	-0.2
HDL Cholesterol	0.3	0.5	2.3	1.0	-0.6	-0.6	-0.1	0.1	0.2	0.1	-0.1	-1.5
LDL Cholesterol	0.3	0.4	1.0	-0.2	-0.5	0.5	0.6	-1.0	0.4	0.5	-0.6	1.0
Lupus	3.0	4.6	17.5	-3.5	2.4	-0.4	0.9	-0.4	0.3	-1.4	1.8	4.2
Neuroticism (2016)	1.0	1.4	4.1	0.5	1.9	-0.9	2.0	0.8	1.6	0.5	0.3	-0.9
Primary Biliary Cirrhosis	0.7	1.0	3.1	-1.5	0.5	-0.4	-1.0	-0.6	1.3	0.3	-0.2	1.8
Rheumatoid Arthritis	0.8	1.1	2.5	-1.6	1.6	0.1	-1.6	-0.6	-0.5	-0.6	0.7	1.2
Schizophrenia (2014)	0.8	1.7	5.2	-0.3	1.8	0.5	0.9	1.1	2.3	1.6	0.4	1.3
Triglycerides	0.2	0.3	1.4	-0.5	-0.0	-0.5	0.7	0.0	-0.1	0.7	0.2	1.2
Type 2 Diabetes (T2D) (2012)	0.7	0.8	2.6	0.2	0.9	-1.6	1.0	0.0	1.1	0.4	1.2	-0.0
Ulcerative Colitis	1.2	1.8	5.9	1.2	1.3	-2.4	1.3	1.0	0.7	0.3	1.8	-0.8
Blood Eosinophil Count	0.2	1.7	4.9	-2.2	0.4	-1.8	0.2	-1.7	0.1	-1.8	0.5	1.0
Blood Platelet Count	1.9	22.5	52.6	-7.2	3.6	-4.5	2.6	-4.7	-3.3	-5.6	4.2	5.4
Blood Red Count	1.7	16.5	37.8	-5.0	5.0	-2.4	4.4	2.1	2.0	1.3	5.0	6.2
Blood White Count	1.1	8.3	37.0	-2.0	1.0	-6.1	4.2	-1.5	1.5	-2.5	1.9	0.5
Heel T-Score	1.3	10.7	33.2	1.0	2.6	5.8	-1.2	4.3	1.4	4.9	0.3	3.0
BMI	0.2	1.3	4.5	2.0	0.2	0.6	-0.5	0.2	-0.8	0.9	-0.9	-2.1
Height	0.3	5.6	29.6	-0.2	2.4	2.7	2.2	-0.2	5.4	-0.6	-1.3	1.0
Waist Hip Ratio (WHR)	1.7	7.5	32.5	-4.3	-0.1	-2.2	0.9	-2.4	1.7	-1.5	0.5	5.7
Systolic Blood Pressure	0.4	2.0	9.1	0.3	-1.6	1.8	-3.0	-1.0	0.3	-0.2	-1.4	-0.1
Smoking Status	0.6	1.4	5.2	-1.1	2.3	-0.5	1.6	-0.4	0.3	-1.0	1.2	0.8
Allergy or Eczema	0.5	1.2	3.7	1.1	-0.3	1.9	-1.1	-0.6	0.7	-0.1	-1.9	-0.5
Cardiovascular Disease	0.2	0.7	2.7	-0.3	-0.4	1.3	-1.6	-0.7	0.1	0.2	0.2	0.9
Hypothyroidism (self reported)	1.0	2.3	10.5	-1.8	1.1	1.4	-1.6	-0.6	-0.7	-0.6	0.4	3.2
Respiratory disease	0.6	1.2	2.9	1.7	-1.2	0.2	0.2	-0.9	-0.5	-0.7	-1.4	-1.7
Type 2 Diabetes (T2D) (2018)	0.8	1.6	7.8	-1.1	0.3	-2.8	0.6	-0.7	-0.5	-0.2	1.7	1.1
Lung FEV1/FVC ratio	1.6	8.0	20.7	1.6	-3.0	3.5	-2.8	2.3	2.8	4.5	-2.0	1.4
Lung FVC	1.2	6.3	24.9	2.0	-2.1	3.4	-5.0	1.3	-1.9	1.2	-1.4	-1.8
Neuroticism	0.2	0.4	1.7	-0.2	1.3	-0.5	1.0	-0.1	0.6	-0.6	-0.2	-0.5
Chronotype (morning person)	0.2	0.5	1.5	1.0	-0.7	0.3	0.4	0.7	0.3	0.8	-1.2	-0.2
Hair Pigment	0.1	1.5	5.7	-2.4	-0.1	-0.8	-0.5	-0.8	-1.6	-0.2	0.8	1.8
Tanning	0.0	0.3	1.6	-0.2	0.1	1.1	0.1	0.1	-0.3	-0.4	-1.3	-0.3
Hand grip strength (left)	0.6	1.5	5.2	-0.2	-0.6	2.3	-1.3	-0.2	1.1	-0.4	-1.7	1.4
Number of treatments/medications taken	0.7	1.2	3.9	-0.3	0.5	-1.8	-0.3	-0.6	-1.2	-0.7	2.0	-1.0
Average weekly spirits intake	0.3	0.4	1.0	0.1	-0.2	0.8	-0.7	-0.9	-1.0	-0.4	-0.4	0.0
Sensitivity / hurt feelings	0.8	1.3	3.5	1.1	-0.7	1.0	-1.1	-1.2	-0.7	-0.6	-1.6	-1.9
Frequency of depressed mood in last 2 weeks	1.2	1.7	7.3	-0.3	2.7	-1.6	1.4	1.2	0.5	0.4	1.5	-0.1
Hearing difficulty/problems: Yes	1.4	2.1	5.4	0.2	2.3	1.1	1.2	1.7	2.0	1.5	1.1	-0.2
Relative age of first facial hair	0.4	0.9	2.5	-1.0	-0.2	-0.7	-0.5	-1.4	-1.6	-1.2	0.2	0.1
Other serious medical condition/disability diagnosed by doctor	0.3	0.4	0.9	1.0	0.1	0.0	-0.1	0.5	-0.3	0.7	0.7	-1.0
Ever used hormone-replacement therapy (HRT)	0.9	1.1	3.9	-0.2	1.7	-2.0	1.1	-0.1	-0.1	-1.1	0.8	0.4
Ever had hysterectomy (womb removed)	1.4	1.6	4.7	-1.2	-0.8	0.9	-0.9	-2.2	-1.7	-1.6	-0.6	0.6
Systolic blood pressure, automated reading	0.5	1.6	6.6	0.2	-0.6	1.4	-2.6	-1.6	-0.6	-0.9	-0.2	-1.3
Eye problems/disorders: Diabetes related eye disease	0.8	0.8	1.7	1.3	-0.9	-0.6	0.2	1.3	0.9	1.3	0.5	-0.6
Angina	0.4	0.5	1.8	-0.3	-1.1	-0.6	-0.9	0.0	-1.3	0.0	0.1	-0.0
Medication for hormone replacement therapy	1.3	1.4	4.8	-0.8	2.2	-0.2	0.8	0.8	1.5	0.9	0.1	1.8
Vitamin and mineral supplements	0.1	0.2	0.6	0.1	-0.2	0.1	0.2	0.5	0.8	-0.2	-0.6	0.3
Supplements: Zinc	1.2	1.3	3.8	-0.5	1.4	-1.9	1.6	0.3	0.6	0.8	1.5	-0.3
Medication: Co-codamol	0.4	0.4	1.0	0.2	0.9	0.4	-0.9	0.8	0.7	1.0	-0.2	0.1
Medication: Metformin	1.0	1.4	3.8	0.3	1.2	-0.5	0.5	1.9	0.7	1.8	1.8	0.2
Diabetes (father)	1.3	1.6	3.1	-1.3	0.8	-1.4	0.3	-1.1	-1.7	-1.4	1.8	0.8
Diabetes (mother)	1.4	1.8	4.7	0.6	0.1	-1.8	1.3	1.3	1.6	1.3	2.2	0.7
Severe depression (siblings)	2.0	2.2	5.9	0.3	1.6	-0.0	1.1	2.4	1.9	1.9	1.6	0.5
Pack years adult smoking proportion	1.4	2.1	6.2	-1.2	2.1	1.6	-1.6	-0.9	0.7	-0.4	0.2	2.5
Impedance of leg (right)	1.4	6.8	21.1	-4.2	0.4	-2.2	-0.4	-3.2	-0.2	-2.6	-0.1	4.6
Leg fat-free mass (left)	1.0	5.4	13.0	3.3	0.8	3.6	0.9	2.1	2.4	2.1	-1.6	-2.4
Trunk fat percentage	0.3	1.2	3.9	1.5	1.1	0.4	0.8	-0.2	0.9	0.0	-1.1	-2.0
Hand grip strength (right)	1.2	3.2	8.6	0.1	-1.9	2.9	-2.0	-1.4	1.0	-0.9	-2.8	0.8
Townsend deprivation index at recruitment	2.5	3.5	7.3	-0.4	2.7	-0.8	2.6	2.1	2.2	1.8	1.6	1.2
Current tobacco smoking	0.4	0.7	2.5	-0.6	1.6	0.1	0.2	-0.4	0.3	-0.5	0.4	1.6
Average weekly fortified wine intake	0.3	0.4	1.4	0.2	1.2	0.9	-0.4	0.5	0.6	0.2	-0.0	0.5
Maternal smoking around birth	0.8	1.1	5.8	-1.2	2.4	0.3	0.8	0.2	0.1	-0.0	1.4	0.4
Fed-up feelings	0.6	1.0	6.1	-0.9	2.5	-0.8	0.2	0.3	-0.4	-0.4	0.8	0.9
Frequency of unenthusiasm / disinterest in last 2 weeks	1.5	2.0	5.4	-0.1	2.3	-1.3	1.3	2.0	1.1	1.2	1.7	-0.1
Relative age voice broke	0.8	1.3	2.9	-1.6	0.5	-0.7	0.4	-1.7	-1.6	-1.2	1.0	0.4
Taking other prescription medications	0.6	0.9	3.7	-0.4	1.3	-1.9	-0.2	-0.1	-0.7	-0.7	1.3	0.3
Age when periods started (menarche)	1.2	2.9	7.8	0.8	2.4	1.3	1.2	2.8	1.9	2.2	-0.1	0.5
Bilateral oophorectomy (both ovaries removed)	0.5	0.6	2.0	1.1	-0.6	0.3	-0.6	-0.5	0.4	-0.4	-1.4	-0.9
Heel bone mineral density (BMD) T-score, automated (left)	1.2	2.6	9.2	-0.5	1.6	1.8	-0.3	1.2	1.8	1.9	0.2	3.0
Tinnitus: Yes, but not now, but have in the past	1.9	2.0	8.7	-2.9	0.6	-1.2	0.1	-1.0	-0.9	-1.3	1.6	1.3
Qualifications: CSEs or equivalent	1.2	1.6	2.9	-1.4	1.7	-1.3	1.4	-0.3	1.1	-0.7	1.3	1.5
Serious illness, injury or assault to yourself	0.4	0.5	1.8	-0.5	0.4	-0.9	-0.7	0.1	-0.7	-0.2	1.3	0.4
High blood pressure	0.4	1.1	4.8	1.0	-0.9	2.2	-0.7	0.6	1.2	0.6	-0.4	-0.8
Hayfever, allergic rhinitis or eczema	0.5	1.0	3.5	0.6	-0.0	1.9	-1.3	-0.7	0.7	0.1	-1.7	0.1
Multivitamins +/- minerals	0.8	1.0	2.8	0.9	0.4	0.2	0.3	1.6	1.2	1.7	0.7	-0.7
Stomach or abdominal pain in last month	3.0	3.7	10.0	-2.6	1.8	-1.9	2.4	0.1	-1.0	-0.4	3.2	1.5
Supplements: Glucosamine	1.3	1.7	3.3	0.1	-0.5	-0.5	-1.4	-1.8	-1.7	-1.6	-1.8	-1.1
Diverticular disease/diverticulitis (self-reported)	3.3	4.0	6.3	0.1	2.1	-2.5	2.5	2.2	2.0	1.6	2.5	0.7
Medication: Atenolol	0.7	0.9	1.5	-0.8	1.2	-0.5	-1.0	-0.6	-1.0	-0.4	1.2	1.2
Medication: Levothyroxine sodium	1.0	1.7	4.2	-1.9	1.4	0.5	-1.0	0.0	-1.5	-1.0	0.8	2.0
Sitting height	0.9	6.0	27.8	1.2	0.5	5.3	-2.4	-1.6	-0.6	-1.4	-3.8	0.0
Chronic bronchitis/emphysema (father)	2.0	2.4	6.2	-0.0	2.0	-0.6	1.4	2.4	1.2	1.3	2.5	0.5
High blood pressure (mother)	2.2	3.2	15.8	1.6	-1.2	4.0	-0.4	0.4	1.1	1.9	-1.6	0.8
Body mass index (BMI)	0.4	1.7	6.4	2.2	0.3	1.0	0.3	1.0	0.1	1.3	-0.3	-2.5
Impedance of leg (left)	1.4	6.7	19.6	-4.3	0.8	-2.5	-0.3	-3.0	-0.1	-2.5	-0.0	4.4
Leg predicted mass (left)	1.0	5.4	13.0	3.4	0.8	3.6	1.0	2.2	2.4	2.1	-1.5	-2.4
Trunk fat mass	0.3	1.4	3.1	1.6	1.4	1.1	0.9	0.1	1.3	0.4	-1.0	-1.8
Waist circumference	0.1	0.3	0.9	-0.3	1.0	-0.2	0.7	-0.7	0.7	-0.2	-0.0	0.4
Number of incorrect matches in round	0.9	1.5	5.8	-0.5	0.1	-2.2	0.9	0.6	-0.8	-0.6	2.4	-0.7
Past tobacco smoking	0.9	1.7	4.3	1.2	-0.3	2.1	-1.6	1.1	1.2	1.4	-1.6	0.1
Alcohol usually taken with meals	2.1	3.3	7.9	0.2	-2.8	1.7	-2.3	-1.8	-0.8	-1.1	-2.6	-1.5
Nervous feelings	0.8	1.5	6.3	-0.9	1.1	-2.5	1.6	-0.6	-0.7	-1.1	0.8	0.2
Frequency of tenseness / restlessness in last 2 weeks	1.4	2.1	5.8	0.8	1.8	-1.6	2.4	1.3	0.7	-0.1	1.8	-1.4
Hearing difficulty/problems with background noise	0.3	0.5	2.1	-0.3	1.5	0.7	0.5	-0.5	0.8	-0.3	-0.3	-0.4
Hair/balding pattern: Pattern 2	1.4	1.7	7.7	-2.8	0.4	-0.2	0.8	-0.8	-0.1	-1.5	0.9	1.8
Had menopause	0.8	1.0	3.1	0.9	-0.8	0.1	-1.3	-0.6	-1.8	-1.2	-0.3	-0.7
Had other major operations	0.7	0.9	2.3	1.2	0.1	-0.0	0.2	1.2	1.1	1.1	-0.4	-1.5
Forced vital capacity (FVC)	1.3	5.0	22.1	1.4	-0.6	4.7	-3.4	0.6	0.3	1.0	-2.8	-0.2
Heel bone mineral density (BMD) T-score, automated (right)	1.1	2.5	10.0	-0.7	1.9	1.5	-0.2	0.8	1.8	1.4	-0.2	3.2
Ever unenthusiastic/disinterested for a whole week	1.1	1.4	4.4	-1.1	1.7	-0.7	1.4	0.9	0.8	0.2	2.1	0.2
Qualifications: None of the above	0.9	2.0	3.3	-1.6	0.8	-1.5	0.7	-1.8	-1.6	-1.8	1.5	0.8
Financial difficulties in last 2 years	0.4	0.5	1.5	0.2	1.2	-0.6	0.9	0.3	0.8	-0.1	1.0	-0.3
Mouth/teeth dental problems	0.8	1.2	2.8	0.6	1.1	-0.9	0.1	1.4	1.2	1.7	1.0	0.9
Heart attack	0.8	1.1	5.1	0.4	-1.4	0.2	-2.3	0.0	-1.4	0.3	-0.4	0.2
Allergy	0.4	1.0	3.1	-0.8	0.8	-1.8	1.0	0.9	-0.6	0.1	1.5	0.6
Pain all over the body in last month	0.5	0.6	1.7	0.2	1.3	-1.2	0.3	0.5	0.7	0.1	1.0	-0.2
Diabetes (self-reported)	0.9	1.3	5.2	0.2	1.6	-1.4	0.6	1.1	0.1	0.9	2.3	0.2
Hayfever/allergic rhinitis (self-reported)	1.0	1.3	3.3	0.4	-1.2	0.6	-1.8	-1.4	-0.4	-1.0	-1.8	0.6
Medication: Ramipril	1.1	1.4	3.6	1.6	-1.0	0.8	-1.9	0.7	1.3	1.0	-1.2	0.0
Medication: Simvastatin	0.3	0.4	1.5	-0.3	-0.6	-1.2	-0.4	-0.9	0.6	-0.1	0.6	-0.0
Fluid intelligence score	0.1	0.3	1.4	-0.0	-0.5	0.6	0.2	-0.2	0.4	-0.1	-1.2	0.2
Illnesses of siblings	0.4	0.5	1.7	-0.7	-0.4	-0.9	-0.3	-0.4	-1.1	-1.3	-0.1	-0.2
Neuroticism score	0.5	1.0	3.5	0.4	1.7	-1.0	1.9	0.1	0.3	-0.2	0.7	-1.0
Weight	0.5	2.5	5.5	2.1	1.2	2.3	0.7	1.0	1.8	1.3	-1.1	-1.7
Impedance of arm (right)	0.6	2.8	6.8	-2.6	0.8	-1.0	-0.0	-2.1	0.9	-2.1	-1.1	2.4
Arm fat percentage (right)	0.2	0.9	4.9	1.3	0.8	0.2	0.6	0.1	0.5	0.4	-0.7	-2.2
Trunk fat-free mass	0.6	3.2	9.9	1.9	0.7	3.2	0.7	2.0	2.1	2.1	-0.7	-0.8
Hip circumference	0.3	1.4	4.9	1.7	1.4	0.6	1.2	0.5	0.5	0.6	0.0	-2.2
Time employed in main current job	2.6	3.0	10.8	-1.1	-1.1	-1.8	-0.7	-1.8	-2.4	-3.3	0.6	-0.7
Alcohol intake versus 10 years previously	0.7	1.1	4.5	-0.4	2.1	0.1	0.5	0.9	0.1	1.0	1.4	1.0
Father’s age at death	1.2	1.6	4.8	-0.0	-1.8	-0.8	-1.0	-0.8	-2.2	-0.9	1.0	-1.6
Worrier / anxious feelings	0.2	0.4	1.6	0.2	1.3	0.6	0.3	0.7	0.6	0.7	0.6	0.0
Frequency of tiredness / lethargy in last 2 weeks	0.7	1.1	9.0	0.1	3.0	0.4	-0.3	0.7	0.4	-0.1	0.4	0.5
Falls in the last year	0.2	0.2	0.9	-0.5	1.0	-0.3	-0.2	-0.4	0.3	-0.2	-0.3	-0.4
Hair/balding pattern: Pattern 3	0.6	0.9	2.7	1.6	0.3	1.3	-0.8	0.8	0.7	0.2	-1.0	-0.6
Number of live births	2.3	3.2	5.9	-0.9	-1.6	-2.4	1.3	-1.5	-1.6	-1.9	2.0	-2.3
Forced expiratory volume in 1-second (FEV1)	2.0	6.7	22.8	1.5	-1.4	4.8	-3.8	1.2	1.1	2.4	-3.0	0.7
Pulse rate	0.5	0.8	3.6	-0.7	0.4	-1.9	0.1	0.9	-0.3	-0.8	1.1	0.2
Happiness	0.6	0.7	4.5	-0.6	2.1	-0.1	0.4	-0.5	-0.7	-0.4	0.4	0.1
Noisy workplace	0.6	0.8	1.9	-1.4	1.1	-0.7	0.2	-0.5	-1.0	-1.1	0.6	0.6
Qualifications: A levels/AS levels or equivalent	1.3	2.8	9.0	1.7	-3.0	1.0	0.2	0.1	0.7	1.0	-2.5	-2.2
Serious illness, injury or assault of a close relative in last 2 years	0.3	0.3	1.1	0.2	0.1	-0.2	0.5	0.5	0.7	-0.3	-0.6	-1.0
Mouth/teeth dental problems: Dentures	0.6	1.1	2.1	0.8	-1.4	1.4	-1.3	-0.8	-1.0	-0.4	-0.9	-0.7
Asthma	0.3	0.7	1.5	1.2	-0.5	-0.1	-0.1	-1.1	-0.2	-1.0	-1.1	-1.1
Medication: Ibuprofen (e.g. Nurofen)	0.9	1.1	2.2	1.0	0.3	0.8	1.1	1.1	1.5	1.2	-0.9	-1.1
Medication: Cholesterol lowering	0.9	1.4	5.4	1.3	-0.4	-0.5	0.4	1.3	1.5	2.3	1.2	-0.1
Depression (self-reported)	0.2	0.2	0.5	-0.5	0.6	-0.1	0.7	-0.2	-0.0	-0.7	0.6	0.1
Medication: Lansoprazole	0.8	1.0	3.3	-0.2	1.0	-1.8	1.0	0.7	-0.4	0.4	1.3	-0.8
Prospective memory result	0.3	0.3	1.9	-0.5	-0.1	-0.2	0.2	0.3	0.4	0.6	1.4	-0.1
Lung cancer (father)	1.3	1.6	4.9	0.3	-2.2	-1.4	0.8	-1.1	0.2	-1.2	-1.0	-1.7
Illnesses of mother	0.5	0.6	2.4	-1.2	0.4	-1.5	0.5	-0.2	-0.2	-0.9	-0.5	-0.2
Forced expiratory volume in 1-second (FEV1), Best measure	1.7	5.5	21.9	0.9	-0.3	4.7	-3.6	1.0	1.1	2.0	-2.6	0.9
Pulse wave Arterial Stiffness index	1.0	1.1	2.9	0.4	0.5	-0.7	0.5	1.7	1.7	1.7	0.3	0.4
Impedance of arm (left)	0.4	1.7	3.3	-1.8	0.8	-1.0	0.7	-1.6	1.1	-1.7	-0.7	1.6
Arm fat mass (right)	0.4	1.7	6.1	2.0	0.8	1.2	0.6	0.7	1.0	1.0	-0.9	-2.5
Trunk predicted mass	0.5	3.1	9.5	1.8	0.8	3.1	0.8	2.0	2.1	2.1	-0.6	-0.7
Standing height	0.4	4.3	15.4	0.2	1.9	3.6	0.8	0.2	3.9	0.2	-1.9	1.4
Length of working week for main job	0.8	0.9	3.7	-0.8	1.2	0.8	0.9	0.0	-0.2	0.1	0.7	1.9
Exposure to tobacco smoke at home	0.6	0.6	3.3	-0.3	-0.6	-1.8	0.2	-0.4	-0.3	-0.8	-1.0	0.4
Breastfed as a baby	0.2	0.3	0.8	-0.8	0.2	-0.7	0.9	-0.1	-0.4	-0.5	0.1	0.1
Tense / ‘highly strung’	0.1	0.2	0.7	-0.4	0.9	-0.3	0.8	-0.0	0.1	-0.3	-0.0	0.6
Seen doctor (GP) for nerves, anxiety, tension or depression	0.9	1.4	3.3	-1.3	1.8	-1.3	1.5	0.6	1.0	0.2	1.1	1.1
Hair/balding pattern: Pattern 4	1.1	2.6	5.5	2.3	-2.4	1.4	-1.0	0.0	0.6	1.1	-2.1	-1.9
Birth weight of first child	0.4	0.7	1.9	0.7	-1.4	0.9	-0.8	0.5	0.9	0.6	-0.5	-0.8
Peak expiratory flow (PEF)	2.1	4.9	18.6	1.6	-0.1	4.3	-2.9	0.8	0.9	1.7	-3.2	0.9
Pulse wave reflection index	0.3	0.4	1.4	-0.0	0.4	0.5	-0.1	0.4	-0.0	1.1	-0.5	1.2
Ever highly irritable/argumentative for 2 days	1.1	1.3	6.0	-0.9	2.4	1.0	-0.2	0.9	0.5	0.4	1.4	0.8
Loud music exposure frequency	0.2	0.2	0.5	-0.7	0.3	0.5	0.2	-0.5	0.1	-0.4	-0.7	0.4
Qualifications: O levels/GCSEs or equivalent	1.9	3.0	6.6	1.7	-2.2	0.4	0.0	1.6	2.6	1.7	-1.5	-2.2
Mouth/teeth dental problems: Bleeding gums	0.7	0.9	3.1	-0.9	0.3	0.4	-0.1	-1.3	-1.2	-1.8	-0.9	0.0
Blood clot in the leg (DVT)	0.5	0.6	2.0	-0.3	-1.4	0.4	0.2	-0.9	-1.1	-0.9	-0.9	-0.3
Medication: Paracetamol	0.3	0.5	1.3	0.2	0.5	-0.7	0.5	0.5	-0.7	0.1	1.1	-1.0
Headache pain in last month	0.6	1.0	2.1	0.3	-0.2	-1.2	0.9	1.4	-0.1	0.9	1.4	-1.4
Medication for cholesterol, blood pressure or diabetes	0.7	1.2	2.9	-1.7	1.3	0.6	0.2	-1.3	-0.6	-1.3	-0.9	1.1
Glaucoma (self-reported)	0.7	0.8	3.4	-0.5	0.4	-0.6	1.0	1.2	0.1	0.8	1.8	0.3
Gout (self-reported)	1.1	1.5	6.1	2.5	-0.1	0.9	-0.3	1.1	0.5	1.2	-0.4	-1.9
Hypothyroidism/myxoedema (self-reported)	1.3	2.5	10.1	-1.8	2.2	1.3	-1.6	-0.1	-0.5	-0.4	0.4	3.2
Medication: Amlodipine	1.0	1.4	3.8	1.6	-1.5	0.8	-0.9	0.1	-0.3	-0.2	-1.6	-2.0
Medication: Ventolin 100micrograms inhaler	0.2	0.2	0.4	0.5	0.3	-0.1	0.5	0.5	0.7	0.3	-0.3	-0.6
Birth weight	0.3	0.7	2.8	0.1	-1.7	1.2	-1.1	-0.7	0.2	0.3	-0.2	-0.2
Chronic bronchitis/emphysema (mother)	0.6	0.7	3.3	0.9	0.7	1.8	0.4	0.5	0.9	0.6	-0.0	-0.2
High blood pressure (siblings)	0.8	1.2	3.2	1.2	-1.0	1.8	-0.6	-0.6	1.2	0.4	-1.4	-1.0
Forced vital capacity (FVC), Best measure	1.2	4.2	19.0	1.4	0.4	4.4	-2.9	0.9	1.0	1.4	-2.2	-0.1
Body fat percentage	0.2	0.8	2.9	1.0	1.1	0.2	0.7	-0.6	0.5	-0.2	-0.9	-1.7
Leg fat percentage (right)	0.1	0.3	1.0	-0.2	0.9	-0.5	0.5	-1.0	-0.1	-0.4	-0.3	-0.3
Arm fat-free mass (right)	0.6	3.1	8.1	2.3	0.8	2.8	1.0	1.8	2.0	1.9	-0.8	-1.1
Exposure to tobacco smoke outside home	0.2	0.2	1.0	-0.2	0.6	-0.1	0.6	0.5	-0.3	0.2	1.0	0.0
Comparative body size at age 10	0.2	0.5	1.8	-0.1	-0.9	0.3	-0.4	-0.7	-1.3	-0.4	-0.3	-1.1
Number of full brothers	2.2	2.7	7.0	-2.6	2.0	-1.0	0.2	-0.8	-0.8	-0.1	2.1	2.6
Worry too long after embarrassment	0.3	0.5	2.6	0.8	0.5	-1.6	0.7	-0.0	0.2	0.0	0.0	-0.9
Seen a psychiatrist for nerves, anxiety, tension or depression	1.1	1.4	3.7	-0.3	1.7	-0.4	1.2	1.1	1.9	0.9	0.2	1.4
Wheeze or whistling in the chest in last year	0.5	0.8	2.9	-0.2	0.6	-1.0	1.7	-0.5	0.5	-1.3	0.8	-0.4
Number of children fathered	0.6	0.6	1.5	0.0	0.4	0.5	-1.0	-1.2	-0.7	-1.1	-0.8	-0.7
Reason for reducing amount of alcohol drunk: Health precaution	0.2	0.3	0.7	0.3	-0.8	-0.1	0.6	0.7	0.7	0.4	-0.2	-0.6
Age at first live birth	0.5	0.9	2.6	-0.4	-0.7	-0.0	-0.6	-1.5	-0.7	-1.0	-1.6	0.7
Pulse wave peak to peak time	0.7	0.8	2.0	-0.3	-0.2	1.1	-0.4	-1.4	-1.1	-1.4	-0.6	-0.3
Health satisfaction	2.0	2.6	8.2	-1.1	2.1	-2.9	1.5	0.3	-0.4	-0.9	2.5	-0.7
Shortness of breath walking on level ground	1.1	1.3	2.7	-1.5	1.6	-1.4	0.7	-0.4	-0.4	-1.4	1.3	0.4
Qualifications: College or University degree	1.8	5.6	15.1	1.8	-2.9	3.5	-2.1	-0.8	1.4	1.2	-3.9	-1.5
Eye problems/disorders: None of the above	1.8	2.1	3.8	1.9	-1.7	1.2	-1.9	-0.0	0.0	0.8	-1.9	-1.6
Mouth/teeth dental problems: Loose teeth	1.3	1.5	3.8	-1.6	0.4	-0.7	-0.7	-1.6	-2.0	-1.8	0.5	0.4
Emphysema/chronic bronchitis	2.6	3.0	10.4	-3.2	1.7	-0.8	0.8	-1.1	-0.0	-1.4	1.1	2.7
Medication for pain relief, constipation, heartburn	1.0	1.7	5.8	-0.9	-1.3	0.6	-1.0	-1.2	-0.3	-0.9	-1.7	2.4
Neck or shoulder pain in last month	4.5	6.4	15.9	-0.3	4.0	-0.9	2.8	3.2	2.4	1.7	3.5	1.6
Medication: Blood pressure	0.8	1.4	3.6	1.7	-1.9	0.4	-1.7	0.7	-0.1	0.3	-0.6	-1.4
Angina (self-reported)	0.4	0.5	2.6	-0.4	-1.0	-0.8	-0.5	0.0	-1.6	-0.2	0.5	0.0
Migraine (self-reported)	0.7	0.9	2.4	0.4	1.6	-0.5	0.6	1.1	0.8	1.4	1.1	-0.2
Medication: Ibuprofen	0.8	0.9	2.8	0.6	0.2	1.0	0.5	1.0	1.7	1.7	-0.5	-0.2
Medication: Allopurinol	1.5	2.0	3.6	1.9	1.4	1.0	1.2	1.9	1.5	1.9	0.9	-0.2
Medication: Omeprazole	1.8	2.1	5.1	-1.3	2.0	-2.2	1.1	1.0	0.9	0.4	2.1	0.6
Medication: Seretide 50 evohaler	2.2	2.5	8.4	-1.6	1.2	-1.7	0.1	-1.9	-1.0	-2.9	1.7	0.0
Mean time to correctly identify matches	0.5	0.9	1.8	1.1	-0.9	0.4	-1.1	1.1	-1.0	1.4	0.2	-0.9
Heart disease (mother)	0.7	0.9	5.4	0.1	-0.3	1.3	-2.3	0.2	-0.4	0.7	0.4	0.4
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.6	1.9	6.9	-1.5	2.6	-0.5	1.6	0.0	-0.6	-0.5	1.8	1.4
Whole body fat mass	0.3	1.1	3.3	1.4	1.2	1.1	0.8	-0.1	0.9	0.2	-0.9	-1.8
Leg fat mass (right)	0.2	0.7	1.2	1.1	1.0	1.0	0.5	-0.2	0.6	0.2	-1.0	-1.1
Arm predicted mass (right)	0.6	2.9	9.1	2.4	0.6	3.0	0.6	1.5	1.6	1.7	-1.0	-1.3
Pulse rate, automated reading	0.4	1.3	4.7	-1.0	1.9	-0.3	0.2	0.5	0.7	-1.2	2.2	0.6
Alcohol intake frequency.	1.1	2.7	10.5	-1.5	3.2	0.1	-0.3	0.8	1.0	0.7	0.6	2.9
Comparative height size at age 10	0.4	2.0	7.0	-1.0	1.4	0.7	0.5	0.4	2.6	0.2	-0.9	2.4
Number of full sisters	2.6	3.2	9.4	0.5	1.1	0.6	1.0	2.6	3.0	3.1	-0.2	0.5
Suffer from ‘nerves’	1.2	1.9	5.5	0.5	1.5	-2.4	2.1	0.9	1.4	0.6	1.4	-0.0
Overall health rating	2.6	5.5	19.1	-1.7	4.4	-2.4	2.3	1.2	0.6	-0.2	3.3	2.1
Chest pain or discomfort	1.3	1.8	7.6	-1.4	0.8	-2.1	0.7	-0.2	-0.4	-0.4	2.8	1.0
Had major operations	1.6	1.9	6.5	0.1	-1.0	-1.0	2.5	1.1	1.1	0.3	2.1	-1.2
Age at last live birth	0.7	1.0	2.9	0.4	-1.7	0.7	-0.5	-1.5	0.1	-0.4	-1.6	-0.3
Family relationship satisfaction	0.5	0.6	1.8	-1.1	0.7	0.0	-0.2	-0.4	-1.4	-0.1	1.0	1.0
Leg pain on walking	0.3	0.4	1.5	0.4	-0.0	-0.0	1.2	0.8	-0.2	0.2	0.3	-1.1
Qualifications: NVQ or HND or HNC or equivalent	2.1	2.6	7.7	1.0	1.8	-0.5	1.6	2.8	2.1	1.8	1.0	0.4
Commuting to job workplace: Car/motor vehicle	0.5	0.6	1.6	-0.4	0.2	-0.9	-0.3	-1.3	0.5	-0.7	-1.1	0.7
Illness, injury, bereavement, stress in last 2 years	0.9	1.1	2.6	1.3	-0.9	1.4	0.1	0.9	1.6	1.4	-0.8	-0.1
Medication: Aspirin	0.5	0.7	1.8	1.0	0.1	-0.7	0.8	0.9	-0.4	0.3	1.1	-1.4
Supplements: Vitamin C	1.4	1.7	5.0	-0.9	-1.1	-0.9	-0.3	-2.2	-2.0	-1.8	-0.3	-0.4
Knee pain experienced in last month	0.8	1.3	3.1	1.5	1.8	1.5	-0.8	0.9	0.3	1.4	-0.2	-0.6
Hypertension (Self-reported)	0.3	0.9	3.8	1.0	-0.9	1.9	-0.8	0.2	0.6	0.2	-0.4	-1.0
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	2.3	2.7	5.5	-0.4	1.6	-1.3	2.3	2.0	1.3	1.8	2.3	0.2
Illnesses of father: Heart disease	0.7	1.0	4.0	-0.8	-2.0	-0.8	-0.1	0.3	-0.8	0.9	0.1	1.4
Illnesses of siblings: Diabetes	1.2	1.5	3.3	-1.8	1.5	-1.4	0.0	-0.1	-0.5	0.3	1.6	1.8
Smoking status: Previous	0.7	1.1	3.3	-0.5	-0.0	-1.8	1.6	-0.1	-0.8	-0.6	1.4	-0.9
Forced expiratory volume in 1-second (FEV1), predicted	0.9	2.0	4.9	-0.3	1.9	1.7	0.0	0.5	2.2	1.1	-0.4	2.2
Whole body fat-free mass	0.7	4.2	11.9	2.6	0.8	3.5	0.9	2.2	2.3	2.2	-1.0	-1.5
Leg fat-free mass (right)	1.1	6.1	13.6	3.6	0.8	3.7	0.9	2.4	2.6	2.3	-1.7	-2.7
Arm fat percentage (left)	0.3	1.3	6.7	1.6	0.7	0.2	0.9	0.2	0.5	0.5	-0.5	-2.6
Average weekly red wine intake	1.0	1.5	4.0	0.7	-1.4	1.7	-0.9	0.1	-0.4	0.7	-1.7	-2.0
Handedness (chirality/laterality): Left-handed	0.3	0.4	1.1	0.3	0.2	-0.8	0.8	1.0	0.5	0.6	0.7	0.4
Mood swings	0.5	0.8	2.4	-0.4	1.0	-0.8	1.6	-1.1	-0.5	-1.3	-0.1	-0.4
Loneliness, isolation	2.4	3.3	8.5	-0.8	2.9	-1.9	2.7	0.8	0.9	-0.1	2.8	0.7
Long-standing illness, disability or infirmity	1.4	2.1	13.0	0.1	3.6	-0.3	0.5	1.3	0.8	0.9	1.5	0.2
Ever had bowel cancer screening	1.8	2.1	4.8	0.4	1.8	-0.2	1.6	1.6	1.5	2.2	1.6	1.0
Diabetes diagnosed by doctor	0.8	1.3	5.5	-0.1	1.4	-1.8	0.5	0.4	-0.8	0.4	2.4	-0.1
Ever had stillbirth, spontaneous miscarriage or termination	0.6	0.6	1.5	-0.3	0.9	-0.0	1.0	1.0	0.5	1.0	-0.1	1.2
Friendships satisfaction	1.2	1.5	5.5	-1.5	2.3	1.0	0.2	-0.6	-0.1	0.0	0.9	1.7
Qualifications: nursing, teaching	1.7	2.6	6.8	2.0	-0.5	2.2	-0.4	2.0	1.7	2.6	-0.9	-0.6
Commuting to job workplace: Walk	0.6	0.6	1.4	-0.3	-1.2	1.1	-0.7	0.5	-1.1	0.9	-0.1	-0.2
Eye problems/disorders: Cataract	0.4	0.4	1.2	-1.0	0.1	-0.2	0.3	-1.1	0.4	-0.9	-0.6	0.3
Mouth/teeth dental problems: Mouth ulcers	0.1	0.1	0.5	-0.1	0.3	0.1	0.7	-0.1	-0.1	-0.1	0.0	-0.5
Medication for cholesterol	0.1	0.1	0.4	0.0	-0.6	0.1	0.2	-0.1	-0.3	-0.5	0.0	0.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.5	0.6	2.5	-0.3	-0.4	-0.3	0.2	-1.6	-0.3	-1.4	-0.4	-0.7
Back pain experienced in last month	1.4	2.0	13.0	-0.9	3.6	0.8	0.2	0.4	-0.6	0.1	0.6	1.6
Mineral and other dietary supplements	0.6	0.8	2.2	-0.6	0.7	-0.1	0.9	1.2	1.3	0.3	0.3	1.5
Breast cancer (self-reported)	1.7	2.0	5.3	-1.1	1.4	-1.6	-0.0	-0.7	-2.3	-1.1	2.2	0.7
Asthma (self-reported)	0.4	0.8	2.0	1.0	-0.6	0.1	-0.5	-1.4	-0.3	-1.1	-1.4	-0.7
Osteoporosis (self-reported)	0.7	0.8	4.2	-2.0	0.2	-0.6	0.8	-0.6	-0.3	-0.9	-0.2	0.9
Osteoarthritis (self-reported)	2.3	3.0	8.3	-0.0	2.9	-1.8	1.8	1.8	1.6	1.9	1.3	1.0
Medication: Aspirin	0.4	0.5	1.3	0.9	-0.1	-0.5	0.6	0.7	-0.6	0.1	1.1	-1.1
Medication: Gliclazide	1.7	1.9	4.9	-1.2	1.5	-2.0	1.0	1.2	-0.3	0.6	2.2	1.5
Illnesses of father: None of the above (group 1)	0.5	0.6	2.1	0.2	-0.4	-0.9	0.4	-0.8	-0.6	-1.2	-0.1	-1.4
Smoking status: Current	0.5	0.8	2.1	-0.9	1.5	-0.4	0.4	-0.8	-0.1	-0.9	0.5	1.4
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.1	2.4	6.3	1.0	-1.9	2.2	-2.5	1.0	-0.3	1.5	-1.1	-0.8
Whole body water mass	0.8	4.4	12.3	2.7	0.8	3.5	0.8	2.2	2.4	2.2	-1.1	-1.5
Leg predicted mass (right)	1.2	6.2	13.3	3.6	0.8	3.6	0.9	2.4	2.6	2.3	-1.7	-2.8
Arm fat mass (left)	0.5	2.0	6.4	2.1	0.8	1.2	0.9	0.9	1.1	1.2	-0.8	-2.5
Number of self-reported non-cancer illnesses	0.1	0.2	0.8	0.7	0.2	0.0	-0.0	0.4	0.5	0.5	0.9	-0.3
Average weekly champagne plus white wine intake	2.5	3.4	13.7	1.9	-3.7	0.6	-1.3	-1.3	-0.2	-0.5	-2.3	-2.0
Miserableness	0.6	1.0	4.4	1.1	0.7	-0.7	1.1	0.7	0.5	-0.1	-0.7	-2.1
Guilty feelings	0.8	1.2	4.0	1.4	1.3	-1.2	0.7	0.6	0.9	0.6	-0.4	-2.0
Wears glasses or contact lenses	0.8	1.0	4.7	1.1	-0.7	-0.2	-1.1	0.3	0.5	0.1	0.7	-2.2
Ever taken oral contraceptive pill	0.4	0.5	1.0	-0.9	0.1	-0.9	0.1	-0.9	-0.8	-0.7	0.0	1.0
Hearing aid user	1.6	1.8	4.0	-1.9	2.0	-0.9	0.8	0.3	-0.1	0.2	1.9	1.9
Mother’s age at death	0.8	1.0	4.9	0.4	-1.2	-2.2	0.5	0.6	-0.3	0.1	0.4	-1.1
Financial situation satisfaction	0.2	0.3	1.4	0.8	0.0	-0.0	0.1	0.5	0.4	0.1	0.2	-1.2
Tinnitus: Yes, now most or all of the time	1.1	1.3	3.5	1.0	0.2	0.1	0.1	1.6	1.9	1.8	-1.0	0.7
Commuting to job workplace: Public transport	0.5	0.6	1.6	-0.4	-1.0	0.3	0.5	1.2	0.2	0.9	1.2	-0.0
Eye problems/disorders: Glaucoma	0.7	0.8	2.3	0.3	1.1	0.8	0.9	1.5	0.4	0.7	1.2	-0.2
Medication: Blood pressure	0.5	0.9	1.5	1.2	-1.1	0.9	-1.1	0.2	0.7	0.7	-1.1	-0.8
Pain type(s) experienced in last month: Hip pain	0.5	0.6	2.3	-0.4	0.2	1.5	-1.0	-0.9	-1.0	-0.7	0.1	-0.1
Supplements: Fish oil (including cod liver oil)	0.8	1.1	2.9	0.8	-1.1	0.9	-1.2	-1.1	-0.6	-0.2	-1.1	-1.7
High cholesterol (Self-reported)	0.5	1.0	2.3	1.4	-0.8	-0.6	0.5	-0.1	1.0	1.5	1.2	-0.8
Medication: Bendroflumethiazide	0.5	0.8	2.6	-0.3	-1.0	-0.5	-1.6	-0.8	-0.3	-1.3	-0.2	-0.9
Medication: Paracetamol	0.2	0.3	1.0	0.2	0.5	-0.2	-0.3	0.2	-0.7	0.5	1.0	-0.6
Medication: Lisinopril	0.9	1.1	3.9	-0.7	-0.3	-0.0	-2.0	-1.5	-1.0	-1.1	-1.0	-0.5
Medication: Atorvastatin	1.0	1.2	3.9	0.3	0.5	-0.3	0.4	1.5	-0.0	2.0	1.9	0.7
Illnesses of father: High blood pressure	0.6	0.8	2.9	-0.5	0.8	1.7	-0.8	0.3	0.6	0.4	-0.4	1.4
Alcohol drinker status: Never	1.4	1.6	6.8	0.5	-0.5	2.6	-1.9	0.1	1.0	0.7	-1.6	0.1
Ever smoked	0.7	1.2	3.2	-1.4	0.1	-1.8	0.6	-1.4	-1.0	-1.4	0.7	0.4
Basal metabolic rate	0.8	4.2	11.5	2.6	1.0	3.4	0.8	2.0	2.3	2.1	-1.3	-1.6
Leg fat percentage (left)	0.1	0.3	1.3	-0.1	1.1	-0.6	0.5	-0.8	-0.1	-0.1	-0.2	-0.5
Arm fat-free mass (left)	0.6	2.9	9.1	2.1	0.9	3.0	0.6	1.7	1.7	1.9	-0.8	-1.2
Number of operations (self-reported)	0.4	0.6	1.9	0.2	-0.1	-0.7	0.4	0.6	0.9	0.9	1.4	-1.1
Average weekly beer plus cider intake	1.8	2.7	5.9	-0.8	2.4	-0.7	2.3	1.3	0.9	1.5	1.6	2.0
Irritability	0.6	1.0	2.7	0.7	1.6	0.1	1.6	1.1	0.4	0.4	-0.0	-1.3
Risk taking	0.8	1.2	3.9	-0.5	0.9	2.0	0.1	0.3	0.5	1.6	0.8	1.3
Ever had prostate specific antigen (PSA) test	0.8	0.9	2.2	0.7	0.3	-1.4	0.0	0.7	-0.2	0.8	1.5	-1.4
Fractured/broken bones in last 5 years	1.2	1.6	5.0	-2.2	2.2	-0.0	0.3	-0.3	-0.5	-1.0	1.1	1.3
Age started oral contraceptive pill	0.9	1.1	4.2	0.3	0.2	-0.3	-1.2	-0.2	-2.0	-1.7	-0.1	-1.0
Diastolic blood pressure, automated reading	4.1	12.6	48.3	2.4	-2.2	6.9	-5.7	-0.8	0.9	0.8	-4.5	-0.9
Ever depressed for a whole week	0.6	0.8	2.6	-1.0	0.6	0.3	0.2	0.8	0.6	0.8	1.6	1.0
Unable to work because of sickness or disability	1.6	2.0	3.8	-1.9	1.9	-1.8	0.6	-0.2	-0.8	-0.6	1.9	1.5
Commuting to job workplace: Cycle	1.2	1.4	3.7	1.6	-1.1	-1.8	0.7	1.0	-0.3	0.2	0.2	-1.9
Myopia	0.4	0.6	1.2	1.1	-0.7	-0.0	-1.1	0.8	0.8	0.7	-0.1	-0.9
Vascular/heart problems diagnosed by doctor	0.5	1.2	3.9	-1.2	1.2	-2.0	1.1	-0.6	-1.1	-0.8	0.1	0.9
Cholesterol lowering medication	0.4	0.6	2.0	0.3	-0.1	-0.2	-1.4	-1.4	-0.8	-0.7	-0.2	-0.8
Medication: Omeprazole (e.g. Zanprol)	2.2	2.7	5.7	-0.8	1.8	-2.2	1.8	2.0	1.1	1.1	2.4	0.7
Pain experienced in last month	1.0	1.7	8.8	0.2	-3.0	0.6	-1.4	-1.3	0.1	-0.3	-1.5	0.3
Supplements: Calcium	1.4	1.5	4.8	-2.2	0.7	-1.6	1.7	-0.7	0.1	-0.6	1.3	0.4
Basal cell carcinoma (self-reported)	0.5	0.6	3.2	0.1	0.6	-0.4	1.8	0.2	0.6	0.1	0.7	-1.0
Heart attack/myocardial infarction (self-reported)	0.8	1.1	4.6	0.3	-1.4	-0.3	-2.2	-0.2	-1.6	0.1	-0.1	0.3
Deep venous thrombosis (DVT) (self-reported)	0.4	0.6	1.6	-0.1	-1.3	0.5	0.1	-0.7	-1.0	-0.7	-1.2	-0.2
Heart disease (siblings)	0.4	0.4	1.6	-0.2	0.8	0.8	0.5	-0.3	-0.5	0.1	0.8	1.3
Alcohol drinker status: Previous	1.2	1.4	2.7	-1.3	1.0	0.2	0.6	0.4	1.6	1.2	1.6	1.6
Pack years of smoking	1.1	1.6	4.3	-0.9	2.1	1.4	-1.6	-0.8	0.5	-0.5	0.1	1.8
Impedance of whole body	0.8	4.0	10.0	-3.2	0.8	-1.8	0.1	-2.5	0.7	-2.4	-0.5	3.1
Leg fat mass (left)	0.2	0.7	1.5	1.0	1.0	1.0	0.4	-0.2	0.5	0.3	-1.1	-1.2
Arm predicted mass (left)	0.5	2.5	8.0	2.1	0.7	2.8	0.3	1.5	1.6	1.7	-0.9	-1.2