[Hub]/) : Traits : Diastolic blood pressure, automated reading :

chr7:6,502,367-7,988,091

Best TWAS P=3.81e-09 · Best GWAS P=2.59e-08 conditioned to 0.48

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex C1GALT1 0.26 0.15 enet 20 0.23 1.1e-27 4.0 5.3 1.4e-07 0.67 0.33 0.66 FALSE
2 GTEx Brain Caudate basal ganglia C1GALT1 0.27 0.18 enet 8 0.20 2.4e-06 4.9 5.5 4.4e-08 0.80 0.03 0.94 FALSE
3 GTEx Brain Nucleus accumbens basal ganglia C1GALT1 0.28 0.00 enet 28 0.01 1.8e-01 4.9 5.6 2.3e-08 0.69 0.03 0.77 FALSE
4 GTEx Colon Sigmoid C1GALT1 0.52 0.25 enet 38 0.31 1.0e-11 4.9 5.7 1.6e-08 0.67 0.05 0.95 FALSE
5 GTEx Colon Transverse C1GALT1 0.32 0.23 lasso 4 0.30 8.0e-15 5.3 5.9 3.8e-09 0.89 0.01 0.99 TRUE
6 GTEx Esophagus Mucosa C1GALT1 0.33 0.19 lasso 6 0.18 2.8e-12 5.5 5.9 4.2e-09 0.89 0.00 0.99 FALSE
7 GTEx Esophagus Muscularis C1GALT1 0.36 0.16 lasso 8 0.27 1.9e-16 4.9 5.9 4.0e-09 0.83 0.03 0.97 FALSE
8 GTEx Lung C1GALT1 0.18 0.13 lasso 3 0.15 1.1e-11 4.9 5.8 8.0e-09 0.75 0.08 0.92 FALSE
9 GTEx Nerve Tibial C1GALT1 0.44 0.28 lasso 12 0.40 2.0e-30 4.2 5.7 1.2e-08 0.82 0.07 0.92 FALSE
10 GTEx Ovary C1GALT1 0.22 0.14 enet 11 0.15 1.8e-04 5.5 5.6 2.0e-08 0.92 0.01 0.96 FALSE
11 GTEx Pancreas C1GALT1 0.44 0.11 enet 24 0.22 8.8e-10 4.2 5.8 4.9e-09 0.81 0.03 0.96 FALSE
12 GTEx Uterus C1GALT1 0.38 0.28 enet 8 0.32 2.0e-07 5.3 5.5 5.0e-08 0.91 0.01 0.97 FALSE
13 METSIM Adipose C1GALT1 0.22 0.16 lasso 9 0.23 5.1e-34 4.9 5.7 1.4e-08 0.76 0.08 0.92 FALSE
14 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma C1GALT1 0.16 0.12 lasso 7 0.14 3.7e-08 5.4 5.5 2.9e-08 0.82 0.01 0.99 FALSE
15 The Cancer Genome Atlas Thyroid Carcinoma C1GALT1 0.05 0.01 lasso 2 0.01 3.8e-02 4.9 5.2 1.5e-07 0.71 0.04 0.56 FALSE