[Hub]/) : Traits : Diastolic blood pressure, automated reading : ← →

chr7:6,502,367-7,988,091

Best TWAS P=3.81e-09 · Best GWAS P=2.59e-08 conditioned to 0.48

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
5	GTEx	Colon Transverse	C1GALT1	0.32	0.23	lasso	4	0.30	8.0e-15	5.3	5.9	3.8e-09	0.89	0.01	0.99	TRUE
7	GTEx	Esophagus Muscularis	C1GALT1	0.36	0.16	lasso	8	0.27	1.9e-16	4.9	5.9	4.0e-09	0.83	0.03	0.97	FALSE
6	GTEx	Esophagus Mucosa	C1GALT1	0.33	0.19	lasso	6	0.18	2.8e-12	5.5	5.9	4.2e-09	0.89	0.00	0.99	FALSE
11	GTEx	Pancreas	C1GALT1	0.44	0.11	enet	24	0.22	8.8e-10	4.2	5.8	4.9e-09	0.81	0.03	0.96	FALSE
8	GTEx	Lung	C1GALT1	0.18	0.13	lasso	3	0.15	1.1e-11	4.9	5.8	8.0e-09	0.75	0.08	0.92	FALSE
9	GTEx	Nerve Tibial	C1GALT1	0.44	0.28	lasso	12	0.40	2.0e-30	4.2	5.7	1.2e-08	0.82	0.07	0.92	FALSE
13	METSIM	Adipose	C1GALT1	0.22	0.16	lasso	9	0.23	5.1e-34	4.9	5.7	1.4e-08	0.76	0.08	0.92	FALSE
4	GTEx	Colon Sigmoid	C1GALT1	0.52	0.25	enet	38	0.31	1.0e-11	4.9	5.7	1.6e-08	0.67	0.05	0.95	FALSE
10	GTEx	Ovary	C1GALT1	0.22	0.14	enet	11	0.15	1.8e-04	5.5	5.6	2.0e-08	0.92	0.01	0.96	FALSE
3	GTEx	Brain Nucleus accumbens basal ganglia	C1GALT1	0.28	0.00	enet	28	0.01	1.8e-01	4.9	5.6	2.3e-08	0.69	0.03	0.77	FALSE
14	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	C1GALT1	0.16	0.12	lasso	7	0.14	3.7e-08	5.4	5.5	2.9e-08	0.82	0.01	0.99	FALSE
2	GTEx	Brain Caudate basal ganglia	C1GALT1	0.27	0.18	enet	8	0.20	2.4e-06	4.9	5.5	4.4e-08	0.80	0.03	0.94	FALSE
12	GTEx	Uterus	C1GALT1	0.38	0.28	enet	8	0.32	2.0e-07	5.3	5.5	5.0e-08	0.91	0.01	0.97	FALSE
1	CommonMind	Brain Pre-frontal Cortex	C1GALT1	0.26	0.15	enet	20	0.23	1.1e-27	4.0	5.3	1.4e-07	0.67	0.33	0.66	FALSE
15	The Cancer Genome Atlas	Thyroid Carcinoma	C1GALT1	0.05	0.01	lasso	2	0.01	3.8e-02	4.9	5.2	1.5e-07	0.71	0.04	0.56	FALSE