Best TWAS P=4.34e-09 · Best GWAS P=3.97e-08 conditioned to 0.251
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | STXBP5 | 0.08 | 0.08 | enet | 17 | 0.09 | 2.4e-11 | 4.8 | -5.9 | 4.3e-09 | -0.82 | 0.06 | 0.94 | TRUE |
2 | ROSMAP | Brain Pre-frontal Cortex | RP11-361F15.2 | 0.05 | 0.06 | lasso | 4 | 0.05 | 1.8e-07 | 5.3 | -5.3 | 9.8e-08 | -0.86 | 0.04 | 0.96 | FALSE |