TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Diastolic blood pressure, automated reading
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chr6:146,826,657-148,410,391
Best TWAS P=4.34e-09 · Best GWAS P=3.97e-08 conditioned to 0.251
146.8M
147M
147.2M
147.4M
147.6M
147.8M
148M
148.2M
148.4M
0
2
4
6
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
CommonMind
Brain Pre-frontal Cortex
STXBP5
0.08
0.08
enet
17
0.09
2.4e-11
4.8
-5.9
4.3e-09
-0.82
0.06
0.94
TRUE
2
ROSMAP
Brain Pre-frontal Cortex
RP11-361F15.2
0.05
0.06
lasso
4
0.05
1.8e-07
5.3
-5.3
9.8e-08
-0.86
0.04
0.96
FALSE