Best TWAS P=2.57e-12 · Best GWAS P=5.5e-12 conditioned to 0.0366
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Brain Putamen basal ganglia | RP11-762H8.1 | 0.29 | 0.07 | lasso | 4 | 0.02 | 1.1e-01 | -6.8 | -5.6 | 2.2e-08 | 0.69 | 0.02 | 0.67 | FALSE |
2 | GTEx | Cells EBV-transformed lymphocytes | ADAMTS7 | 0.32 | 0.11 | lasso | 5 | 0.17 | 2.8e-06 | -6.7 | -7.0 | 2.6e-12 | 0.81 | 0.01 | 0.98 | TRUE |