Best TWAS P=2.26e-07 · Best GWAS P=2.54e-07 conditioned to 0.303
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | The Cancer Genome Atlas | Pancreatic Adenocarcinoma | SLC5A11 | 0.3 | 0.33 | lasso | 2 | 0.32 | 2.8e-14 | -4.9 | -5.2 | 2.3e-07 | 0.92 | 0.01 | 0.99 | TRUE |
| 2 | The Cancer Genome Atlas | Skin Cutaneous Melanoma | SLC5A11 | 0.2 | 0.05 | lasso | 4 | 0.04 | 2.8e-02 | -5.0 | -5.2 | 2.3e-07 | 0.90 | 0.00 | 0.75 | FALSE |