TWAS
hub
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Models
Genes
Traits
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Traits
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Diastolic blood pressure, automated reading
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chr16:24,614,505-25,167,985
Best TWAS P=2.26e-07 · Best GWAS P=2.54e-07 conditioned to 0.303
24.6M
24.7M
24.8M
24.9M
25M
25.1M
25.2M
0
2
4
6
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
The Cancer Genome Atlas
Pancreatic Adenocarcinoma
SLC5A11
0.3
0.33
lasso
2
0.32
2.8e-14
-4.9
-5.2
2.3e-07
0.92
0.01
0.99
TRUE
2
The Cancer Genome Atlas
Skin Cutaneous Melanoma
SLC5A11
0.2
0.05
lasso
4
0.04
2.8e-02
-5.0
-5.2
2.3e-07
0.90
0.00
0.75
FALSE