Best TWAS P=9.89e-09 · Best GWAS P=8.46e-09 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Tibial | PLEKHJ1 | 0.14 | 0.09 | lasso | 2 | 0.06 | 3.3e-05 | 5.8 | 5.7 | 9.9e-09 | 1.00 | 0.00 | 1.00 | TRUE |
| 2 | GTEx | Esophagus Muscularis | ATP8B3 | 0.33 | 0.23 | enet | 31 | 0.25 | 2.1e-15 | -4.6 | -5.2 | 2.5e-07 | -0.11 | 0.21 | 0.79 | TRUE |
| 3 | ROSMAP | Brain Pre-frontal Cortex | DOT1L | 0.08 | 0.06 | lasso | 5 | 0.07 | 8.0e-09 | 5.1 | 5.6 | 2.7e-08 | 0.89 | 0.00 | 1.00 | FALSE |