[Hub]/) : Traits : Systolic blood pressure, automated reading : ← →

chr17:75,977,988-77,462,467

Best TWAS P=1.76e-09 · Best GWAS P=2.62e-10 conditioned to 0.0186

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex USP36 0.14 0.13 lasso 3 0.13 1.7e-15 5.7 -5.9 3.9e-09 -0.96 0.02 0.98 FALSE
2 GTEx Adipose Subcutaneous CYTH1 0.13 0.03 lasso 5 0.04 5.7e-04 5.7 5.2 2.2e-07 0.84 0.08 0.67 FALSE
3 GTEx Brain Cerebellum USP36 0.31 0.20 enet 18 0.13 9.7e-05 5.4 -5.3 1.5e-07 -0.79 0.04 0.89 FALSE
4 GTEx Brain Nucleus accumbens basal ganglia USP36 0.36 0.23 lasso 5 0.20 4.8e-06 6.1 -6.0 2.3e-09 -0.98 0.02 0.97 FALSE
5 GTEx Esophagus Mucosa USP36 0.11 0.04 enet 13 0.06 1.1e-04 6.0 -5.8 6.9e-09 -0.88 0.02 0.98 FALSE
6 GTEx Esophagus Muscularis USP36 0.18 0.16 lasso 3 0.08 2.5e-05 5.7 5.2 2.2e-07 0.87 0.02 0.98 FALSE
7 GTEx Muscle Skeletal CYTH1 0.13 0.12 lasso 3 0.13 2.5e-12 5.7 5.4 7.9e-08 0.93 0.11 0.89 FALSE
8 GTEx Testis USP36 0.32 0.24 lasso 6 0.26 6.2e-12 4.4 -5.4 8.6e-08 -0.93 0.05 0.95 FALSE
9 GTEx Thyroid CYTH1 0.24 0.07 lasso 11 0.06 3.4e-05 5.4 5.7 1.3e-08 0.85 0.13 0.86 FALSE
10 The Cancer Genome Atlas Brain Lower Grade Glioma USP36 0.04 0.00 blup 57 0.01 2.9e-02 6.0 -6.0 1.8e-09 -0.83 0.01 0.54 TRUE