[Hub]/) : Traits : Systolic blood pressure, automated reading : ← →

chr2:218,421,136-219,878,756

Best TWAS P=8.05e-09 · Best GWAS P=9.29e-08 conditioned to 4.73e-07

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Artery Aorta TMBIM1 0.17 0.20 enet 29 0.19 1.2e-10 5.1 -5.4 7.8e-08 -0.01 0.03 0.96 FALSE
2 GTEx Artery Coronary TMBIM1 0.22 0.08 lasso 1 0.03 3.6e-02 5.2 -5.2 2.6e-07 0.00 0.03 0.79 FALSE
3 GTEx Artery Tibial RP11-378A13.1 0.20 0.17 enet 13 0.24 7.6e-19 4.0 -5.2 1.7e-07 0.01 0.04 0.96 FALSE
4 GTEx Cells EBV-transformed lymphocytes RP11-378A13.1 0.18 0.14 lasso 6 0.13 4.6e-05 5.3 -5.5 4.9e-08 -0.03 0.03 0.93 FALSE
5 GTEx Cells Transformed fibroblasts TMBIM1 0.15 0.25 lasso 3 0.27 2.2e-20 5.1 -5.1 3.0e-07 0.01 0.02 0.98 FALSE
6 GTEx Heart Atrial Appendage TMBIM1 0.11 0.09 lasso 2 0.08 1.8e-04 5.2 -5.3 1.4e-07 0.01 0.02 0.97 FALSE
7 GTEx Skin Not Sun Exposed Suprapubic RP11-378A13.1 0.26 0.25 lasso 8 0.28 5.6e-16 5.0 -5.2 2.4e-07 0.00 0.04 0.96 FALSE
8 GTEx Skin Sun Exposed Lower leg PNKD 0.27 0.29 lasso 8 0.34 3.9e-29 5.0 -5.1 2.8e-07 0.00 0.04 0.96 FALSE
9 GTEx Testis PNKD 0.20 0.19 lasso 3 0.19 1.2e-08 5.2 -5.2 2.1e-07 -0.01 0.02 0.98 FALSE
10 GTEx Testis TMBIM1 0.27 0.13 enet 20 0.15 2.7e-07 5.0 -5.8 8.0e-09 -0.05 0.02 0.97 TRUE
11 METSIM Adipose TMBIM1 0.14 0.15 lasso 11 0.14 1.3e-20 5.1 -5.2 1.8e-07 0.02 0.02 0.98 FALSE
12 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma TMBIM1 0.10 0.04 blup 49 0.06 3.0e-03 5.1 -5.3 1.5e-07 0.02 0.02 0.83 FALSE
13 The Cancer Genome Atlas Soft Tissue Sarcoma TMBIM1 0.07 0.04 blup 49 0.03 4.8e-03 5.0 -5.3 1.1e-07 0.02 0.02 0.71 FALSE
14 The Cancer Genome Atlas Thyroid Carcinoma TMBIM1 0.02 0.02 blup 49 0.02 9.3e-03 5.1 -5.5 4.2e-08 0.02 0.02 0.70 FALSE