Best TWAS P=6.05e-10 · Best GWAS P=6.96e-10 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | The Cancer Genome Atlas | Colon Adenocarcinoma | UGT2B7 | 0.07 | 0.06 | enet | 11 | 0.06 | 1.5e-04 | -6.1 | 6.2 | 6.0e-10 | -0.99 | 0.02 | 0.97 | TRUE |
| 2 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | UGT2B10 | 0.07 | 0.02 | lasso | 3 | 0.02 | 7.1e-03 | 5.1 | 5.3 | 1.2e-07 | -0.64 | 0.01 | 0.58 | FALSE |
| 3 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | UGT2B10 | 0.07 | 0.07 | lasso | 2 | 0.07 | 4.4e-05 | 5.1 | 5.2 | 2.0e-07 | -0.63 | 0.04 | 0.93 | FALSE |
| 4 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | UGT2B7 | 0.08 | 0.07 | lasso | 2 | 0.06 | 2.6e-07 | 5.1 | -5.2 | 2.5e-07 | 0.61 | 0.74 | 0.25 | FALSE |
| 5 | The Cancer Genome Atlas | Skin Cutaneous Melanoma | UGT2B7 | 0.21 | 0.16 | lasso | 3 | 0.15 | 8.6e-05 | 5.1 | -5.3 | 1.2e-07 | 0.66 | 0.12 | 0.30 | FALSE |
| 6 | The Cancer Genome Atlas | Thyroid Carcinoma | UGT2B7 | 0.04 | 0.04 | lasso | 2 | 0.03 | 9.8e-04 | 5.1 | -5.2 | 2.2e-07 | 0.62 | 0.05 | 0.44 | FALSE |
| 7 | The Cancer Genome Atlas | Uterine Corpus Endometrial Carcinoma | UGT2B7 | 0.19 | 0.13 | enet | 26 | 0.17 | 2.0e-05 | -6.1 | -5.3 | 1.4e-07 | 0.88 | 0.03 | 0.95 | FALSE |