Hub : Genes

UGT2B7

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	TCGA	Breast Invasive Carcinoma	0.0442	0.0332	4.6e-04	0.016	0.008	0.009	NA	0.008	2.6e-04	6.2e-03	5.6e-03	NA	6.9e-03
2	TCGA	Colon Adenocarcinoma	0.0680	0.0380	3.1e-05	0.064	0.059	0.064	NA	0.057	1.5e-04	2.5e-04	1.5e-04	NA	3.2e-04
3	TCGA	Kidney Renal Clear Cell Carcinoma	0.3157	0.0804	0.0e+00	0.177	0.178	0.181	NA	0.171	1.6e-19	1.3e-19	6.8e-20	NA	8.6e-19
4	TCGA	Kidney Renal Papillary Cell Carcinoma	0.1070	0.0660	4.1e-03	0.049	0.039	0.028	NA	0.054	8.6e-04	2.6e-03	9.8e-03	NA	4.7e-04
5	TCGA	Lung Squamous Cell Carcinoma	0.0836	0.0410	3.3e-06	0.066	0.044	0.051	NA	0.059	5.0e-08	9.1e-06	1.8e-06	NA	2.6e-07
6	TCGA	Ovarian Serous Cystadenocarcinoma	0.3300	0.1210	5.6e-10	0.140	0.121	0.149	NA	0.137	9.7e-10	1.6e-08	2.7e-10	NA	1.5e-09
7	TCGA	Prostate Adenocarcinoma	0.0906	0.0617	2.6e-03	0.003	0.016	0.008	NA	0.012	1.6e-01	7.5e-03	4.3e-02	NA	1.8e-02
8	TCGA	Skin Cutaneous Melanoma	0.2130	0.1040	4.6e-04	0.164	0.117	0.110	NA	0.149	3.6e-05	5.0e-04	7.3e-04	NA	8.6e-05
9	TCGA	Thyroid Carcinoma	0.0420	0.0310	7.2e-03	0.038	0.017	0.024	NA	0.027	1.3e-04	7.9e-03	1.9e-03	NA	9.8e-04
10	TCGA	Uterine Corpus Endometrial Carcinoma	0.1930	0.0940	3.6e-05	0.126	0.158	0.168	NA	0.164	2.3e-04	3.5e-05	2.0e-05	NA	2.5e-05

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10
Bipolar Disorder (2018)	0.4	0.6	1.3	0.6	-1.1	0.1	-0.8	0.0	0.9	0.3	1.1	1.0	0.7
Bipolar Disorder or Schizophrenia	0.4	0.9	2.5	1.6	-0.4	-0.2	-0.9	0.0	0.1	0.8	1.5	1.5	0.1
Depressed Affect (Nagel 2018)	1.0	2.1	5.3	-2.3	1.1	-0.0	1.2	-1.5	-0.1	-2.1	-1.3	-1.5	-1.3
Depression (Nagel 2018)	0.1	0.1	0.4	-0.5	-0.5	0.6	-0.0	0.3	0.3	-0.2	0.4	0.4	0.2
Intelligence (Savage-Jansen 2018)	0.1	0.3	0.9	-0.3	0.1	1.0	0.5	0.0	-0.8	-0.8	0.0	0.0	-0.7
Neuroticism (Nagel 2018)	1.4	3.3	5.8	-2.4	1.8	0.4	1.7	-2.0	-0.8	-2.4	-1.9	-2.0	-1.9
Schizophrenia (2018)	0.3	0.6	2.1	1.4	0.4	-0.4	-0.5	0.0	-0.5	0.8	1.0	1.1	-0.5
Schizophrenia vs Biploar Disorder	0.4	0.6	2.7	0.6	1.7	-1.2	-0.2	0.0	-0.5	0.3	0.0	0.2	-0.9
Worry (Nagel 2018)	1.3	2.7	5.3	-2.3	1.0	1.1	1.7	-1.7	-0.8	-2.3	-1.6	-1.7	-1.5
Alzheimer’s Disease (in mother)	0.1	0.1	0.4	0.2	0.1	-0.1	-0.2	0.4	-0.1	-0.6	0.5	0.4	-0.5
Alzheimer’s Disease (in father)	0.6	0.7	1.8	0.9	0.3	-1.4	-1.0	0.9	0.3	0.2	1.0	0.9	-0.2
Alzheimer’s Disease (including proxy)	0.3	0.5	1.3	0.2	0.8	-1.2	-0.6	0.5	0.1	-0.8	0.7	0.5	-0.9
Crohns Disease (2017)	0.1	0.2	0.7	0.8	0.1	0.8	0.1	0.3	-0.6	0.1	0.2	0.3	-0.4
Irritable Bowel Disease (IBD)	0.3	0.7	3.0	1.0	-0.3	1.7	0.2	0.4	-1.3	0.3	0.2	0.4	-0.6
Ulcerative Colitis (UC)	0.5	1.0	4.0	1.3	-0.6	2.0	-0.1	0.7	-1.4	0.7	0.5	0.7	-0.4
Major Depression (MDD)	0.3	0.3	1.6	0.2	0.5	-1.3	-0.4	0.3	0.8	-0.0	0.3	0.2	-0.2
Reaction Time	1.0	1.8	3.2	1.4	-0.5	-1.8	-1.4	1.2	1.4	1.8	1.2	1.2	1.2
Verbal and Numeric Reasoning (VNR)	0.4	0.9	1.4	-0.5	0.5	1.1	1.1	-0.8	-1.1	-1.1	-0.7	-0.8	-1.2
Breast Cancer	1.1	2.7	5.0	1.9	-1.4	-1.3	-1.9	1.5	1.3	2.2	1.5	1.5	1.7
Ovarian Cancer	0.7	0.9	4.2	0.3	0.3	2.0	0.9	-0.3	-1.6	0.2	-0.6	-0.3	-0.7
Prostate Cancer	0.8	1.2	1.7	0.9	-1.3	-0.6	-1.1	1.1	1.0	0.8	1.1	1.1	1.3
Age at First Birth	0.4	0.6	1.7	1.3	0.2	0.4	-0.4	1.0	-0.9	0.1	0.9	0.9	-0.9
Bipolar Disorder (2011)	1.4	1.3	2.7	1.0	-1.6	0.2	-1.1	0.0	1.1	0.9	1.6	1.6	1.1
Body Mass Index (BMI) (2010)	0.8	1.1	1.7	-1.3	0.3	0.9	1.3	-1.3	-0.4	-1.2	-1.1	-1.3	-0.6
Coronary Artery Disease (CAD)	1.3	1.5	3.5	0.2	1.8	1.3	1.2	-0.7	-1.8	-0.9	-0.6	-0.6	-1.9
Crohns Disease (2012)	0.3	0.5	1.6	1.3	0.1	0.3	-0.5	0.0	-0.4	0.7	1.0	1.1	-0.3
Mean Putamen Volume	0.6	0.7	2.2	0.1	-0.9	-0.9	-0.8	0.5	1.5	0.4	0.6	0.5	1.3
Fasting Glucose	0.2	0.2	1.1	-1.0	0.4	0.1	0.4	-0.2	0.2	-0.7	-0.1	-0.2	-0.4
HbA1C	1.1	1.2	3.5	0.1	-1.9	-0.1	-1.1	1.1	1.2	0.1	1.4	1.1	1.2
HDL Cholesterol	1.2	2.0	2.9	1.2	-1.2	-1.2	-1.7	1.6	1.0	1.5	1.5	1.6	1.3
LDL Cholesterol	0.1	0.2	1.1	-0.1	0.6	-1.0	-0.2	0.1	0.5	-0.4	0.1	0.1	-0.2
Lupus	0.1	0.1	0.3	-0.5	0.3	-0.2	-0.0	-0.1	-0.2	-0.5	-0.1	-0.1	-0.4
Neuroticism (2016)	0.9	1.3	6.6	-0.6	2.6	-1.2	0.4	-0.6	-0.5	-0.8	-0.7	-0.6	-1.6
Primary Biliary Cirrhosis	0.7	1.1	1.4	-1.2	0.8	0.9	1.2	-1.0	-0.9	-1.2	-1.1	-1.0	-0.9
Rheumatoid Arthritis	1.8	2.5	6.9	2.6	-0.7	-0.6	-1.8	0.0	0.3	2.4	1.9	2.1	0.9
Schizophrenia (2014)	0.7	1.6	3.7	1.9	-0.5	-0.6	-1.3	0.0	0.3	1.8	1.7	1.9	0.6
Triglycerides	0.1	0.2	0.3	-0.3	0.6	-0.3	0.3	-0.4	-0.0	-0.5	-0.3	-0.4	-0.6
Type 2 Diabetes (T2D) (2012)	0.6	0.6	1.3	1.1	-0.5	-0.6	-0.8	0.9	1.0	0.2	1.1	0.9	0.3
Ulcerative Colitis	0.5	0.7	3.1	0.2	0.3	1.7	0.5	0.0	-1.8	0.1	-0.1	0.1	-1.0
Blood Eosinophil Count	0.1	0.6	2.2	-0.1	1.5	-0.8	0.4	-0.7	-0.4	-0.4	-0.7	-0.7	-1.0
Blood Platelet Count	0.1	1.4	5.0	0.8	-2.2	0.8	-0.7	1.1	0.4	0.9	1.1	1.1	1.5
Blood Red Count	0.8	7.5	18.2	0.4	-4.3	-1.3	-2.6	2.0	3.6	2.0	2.2	2.0	4.2
Blood White Count	0.3	2.0	2.7	1.0	-1.3	-1.4	-1.6	1.5	1.5	1.2	1.6	1.5	1.5
Heel T-Score	0.0	0.2	0.7	0.3	0.4	0.3	0.4	-0.3	-0.2	0.8	-0.4	-0.4	-0.1
BMI	0.0	0.2	0.7	0.8	0.5	0.0	-0.0	0.0	-0.7	0.6	-0.2	0.0	-0.2
Height	0.1	2.3	4.2	1.4	-1.7	-0.5	-1.7	1.9	1.4	0.6	2.0	1.9	1.2
Waist Hip Ratio (WHR)	0.4	1.9	5.5	-0.4	0.9	2.3	1.4	-0.6	-2.0	-1.5	-0.6	-0.6	-1.8
Systolic Blood Pressure	3.3	16.6	32.4	-3.0	5.7	0.5	4.1	-4.4	-3.8	-3.4	-4.5	-4.4	-4.8
Smoking Status	2.4	5.8	9.9	2.5	-1.4	-1.3	-2.9	3.1	1.2	2.6	2.9	3.1	1.7
Allergy or Eczema	1.1	2.8	6.9	-2.6	0.9	-0.1	1.4	-2.2	0.1	-2.3	-1.9	-2.2	-0.6
Cardiovascular Disease	2.1	6.9	17.2	-1.4	4.2	0.2	2.3	-2.4	-3.1	-2.0	-2.5	-2.4	-3.6
Hypothyroidism (self reported)	0.1	0.2	0.6	-0.8	-0.0	-0.7	-0.2	-0.1	0.6	-0.7	-0.0	-0.1	0.4
Respiratory disease	1.1	2.5	4.5	-0.5	1.9	1.5	1.8	-1.6	-2.1	-0.6	-1.8	-1.6	-1.7
Type 2 Diabetes (T2D) (2018)	0.1	0.3	1.0	0.5	1.0	-0.7	0.2	-0.1	-0.2	-0.4	-0.1	-0.1	-0.8
Lung FEV1/FVC ratio	0.1	0.4	1.0	-0.5	-0.6	-0.6	-1.0	0.6	0.8	0.1	0.6	0.6	0.7
Lung FVC	0.1	0.3	0.6	-0.6	-0.6	0.2	0.5	-0.7	0.3	0.0	-0.7	-0.7	0.3
Neuroticism	1.4	3.4	6.1	-1.9	1.7	1.0	2.0	-1.7	-1.4	-2.5	-1.6	-1.8	-2.4
Chronotype (morning person)	0.6	1.3	3.4	-0.4	-1.0	-1.6	-1.2	0.5	1.8	1.0	0.5	0.5	1.6
Hair Pigment	0.1	1.4	2.3	0.1	-0.7	-1.1	-1.4	1.4	1.5	1.2	1.4	1.4	0.9
Tanning	0.1	1.2	2.2	1.0	-1.4	0.5	-1.0	1.0	0.7	1.5	1.0	1.0	1.4
Hand grip strength (left)	0.0	0.0	0.2	0.1	-0.4	0.2	-0.0	0.1	-0.0	-0.2	0.2	0.1	0.1
Number of treatments/medications taken	2.6	4.7	8.0	-2.3	2.8	0.2	2.0	-2.3	-1.5	-2.4	-2.3	-2.3	-2.5
Average weekly spirits intake	0.7	0.9	3.0	-0.2	0.4	1.7	1.0	-0.4	-1.5	-0.9	-0.3	-0.4	-1.3
Sensitivity / hurt feelings	1.7	3.0	3.8	-1.5	1.7	1.1	1.8	-1.7	-1.9	-1.7	-1.8	-1.7	-1.9
Frequency of depressed mood in last 2 weeks	0.2	0.3	0.9	0.3	-0.5	0.9	-0.1	0.7	-0.3	-0.2	0.7	0.7	-0.2
Hearing difficulty/problems: Yes	1.8	2.8	6.1	-1.4	2.5	-0.1	1.6	-1.9	-1.0	-1.4	-1.8	-1.9	-1.8
Relative age of first facial hair	0.2	0.4	1.1	0.9	-0.0	1.0	0.5	0.2	-0.8	-0.3	0.3	0.2	-0.8
Other serious medical condition/disability diagnosed by doctor	0.7	0.9	1.8	1.0	-0.5	-0.8	-1.1	1.3	0.6	0.6	1.3	1.3	0.2
Ever used hormone-replacement therapy (HRT)	0.6	0.8	1.5	-1.0	0.8	0.0	0.9	-1.2	-0.7	-0.7	-1.2	-1.2	-0.6
Ever had hysterectomy (womb removed)	0.3	0.4	1.0	-1.0	0.4	-0.2	0.5	-0.8	0.2	-0.5	-0.8	-0.8	-0.1
Systolic blood pressure, automated reading	7.5	21.9	38.3	-3.6	6.2	0.8	4.8	-5.2	-4.4	-3.9	-5.3	-5.2	-5.3
Eye problems/disorders: Diabetes related eye disease	0.6	0.7	2.2	0.8	1.0	0.7	0.5	0.3	-1.5	-0.4	0.2	0.3	-1.5
Angina	0.6	0.8	2.1	-0.9	1.5	-0.6	0.4	-0.6	-0.6	-1.3	-0.5	-0.6	-1.4
Medication for hormone replacement therapy	2.3	2.6	4.4	1.8	-1.1	-1.5	-1.8	1.5	1.4	2.1	1.5	1.5	1.7
Vitamin and mineral supplements	0.3	0.5	2.2	0.6	0.5	-1.5	-0.7	0.4	0.8	0.5	0.3	0.4	0.3
Supplements: Zinc	0.8	0.8	2.1	1.4	-0.6	-0.2	-0.9	1.0	0.5	1.2	1.0	1.0	0.7
Medication: Co-codamol	0.5	0.6	1.0	-0.7	1.0	0.5	0.8	-0.8	-0.7	-0.5	-0.9	-0.8	-0.9
Medication: Metformin	0.8	1.1	3.1	-1.4	0.7	-0.6	0.8	-1.2	0.1	-1.8	-1.0	-1.2	-0.8
Diabetes (father)	0.5	0.6	1.4	1.0	0.5	-0.3	-0.7	1.2	-0.3	0.2	1.1	1.2	-0.6
Diabetes (mother)	0.4	0.5	1.9	1.4	0.2	0.8	-0.1	0.4	-0.7	1.1	0.3	0.4	-0.1
Severe depression (siblings)	1.4	1.6	2.8	-1.1	1.7	0.3	1.2	-1.2	-1.1	-1.5	-1.1	-1.2	-1.7
Pack years adult smoking proportion	1.4	2.1	5.3	-0.3	2.3	0.9	1.4	-1.1	-2.2	-0.6	-1.4	-1.1	-2.0
Impedance of leg (right)	0.0	0.2	0.6	0.2	-0.4	0.0	-0.5	0.7	-0.1	-0.1	0.8	0.7	0.0
Leg fat-free mass (left)	0.0	0.1	0.4	0.5	-0.1	0.6	-0.1	0.2	-0.5	0.5	0.0	0.2	0.1
Trunk fat percentage	0.0	0.1	0.4	-0.1	0.2	-0.1	0.3	-0.5	-0.1	0.3	-0.6	-0.5	0.2
Hand grip strength (right)	0.5	1.3	2.5	1.6	-1.1	0.0	-1.1	1.4	0.2	1.1	1.3	1.4	0.9
Townsend deprivation index at recruitment	0.1	0.2	0.4	0.4	-0.3	-0.6	-0.4	0.5	0.5	-0.2	0.6	0.5	0.1
Current tobacco smoking	1.9	3.0	5.1	1.6	-1.9	-0.5	-1.9	2.2	1.0	1.6	2.1	2.2	1.6
Average weekly fortified wine intake	1.0	1.1	2.7	-0.4	1.2	1.2	1.2	-0.6	-1.4	-1.0	-0.7	-0.6	-1.6
Maternal smoking around birth	0.9	1.3	5.0	0.3	0.3	2.2	1.2	-0.2	-2.0	-0.6	-0.4	-0.2	-1.3
Fed-up feelings	0.5	1.0	1.4	-1.1	1.0	-0.1	1.0	-1.1	-0.3	-1.2	-1.0	-1.2	-1.1
Frequency of unenthusiasm / disinterest in last 2 weeks	0.2	0.2	0.5	-0.1	-0.6	0.7	-0.1	0.6	0.3	-0.3	0.7	0.6	0.0
Relative age voice broke	1.1	1.6	2.6	1.6	-0.5	-1.6	-1.3	1.3	1.6	0.9	1.6	1.3	0.6
Taking other prescription medications	1.7	2.6	4.3	-2.0	2.0	0.0	1.4	-1.5	-1.0	-2.1	-1.4	-1.5	-2.0
Age when periods started (menarche)	0.6	1.3	5.0	2.2	-0.1	0.1	-0.7	1.5	-0.5	1.2	1.3	1.5	-0.2
Bilateral oophorectomy (both ovaries removed)	0.7	0.8	3.6	-0.1	-0.1	-1.9	-0.7	-0.0	1.6	0.3	0.1	-0.0	0.8
Heel bone mineral density (BMD) T-score, automated (left)	0.0	0.1	0.5	0.3	-0.3	-0.2	-0.0	-0.2	0.3	0.7	-0.1	-0.2	0.3
Tinnitus: Yes, but not now, but have in the past	3.4	3.7	5.8	-2.3	0.4	2.0	2.3	-2.4	-1.0	-1.8	-2.3	-2.4	-0.7
Qualifications: CSEs or equivalent	1.1	1.4	3.0	1.5	-0.8	-0.9	-1.3	1.0	1.0	1.7	1.0	1.1	1.4
Serious illness, injury or assault to yourself	0.7	0.8	1.7	-1.3	0.9	0.3	0.8	-0.9	-0.5	-1.2	-0.8	-0.9	-1.0
High blood pressure	3.9	10.8	18.8	-3.2	4.3	-0.0	3.1	-3.7	-2.6	-3.0	-3.8	-3.7	-3.5
Hayfever, allergic rhinitis or eczema	0.8	1.7	4.1	-2.0	0.2	0.2	1.2	-1.7	0.2	-2.0	-1.4	-1.7	-0.3
Multivitamins +/- minerals	1.0	1.3	2.9	-1.7	0.1	1.0	1.4	-1.4	-0.5	-1.2	-1.3	-1.4	-0.4
Stomach or abdominal pain in last month	0.3	0.3	1.5	1.2	-0.2	0.3	-0.3	0.6	-0.3	0.9	0.5	0.6	0.0
Supplements: Glucosamine	0.7	0.9	1.7	-0.9	1.1	-0.1	0.9	-1.1	-0.3	-1.3	-0.9	-1.1	-1.0
Diverticular disease/diverticulitis (self-reported)	1.0	1.2	2.3	-0.9	0.6	0.8	1.5	-1.5	-0.7	-0.7	-1.5	-1.5	-0.7
Medication: Atenolol	0.7	0.9	3.6	-0.1	1.9	-0.3	0.6	-0.7	-1.1	-0.1	-0.9	-0.7	-1.3
Medication: Levothyroxine sodium	0.6	1.1	2.3	-1.3	1.5	-1.4	0.4	-0.9	-0.1	-1.4	-0.8	-0.8	-0.8
Sitting height	0.7	5.1	7.3	2.1	-2.1	-1.2	-2.7	2.6	1.7	2.4	2.4	2.6	2.4
Chronic bronchitis/emphysema (father)	0.3	0.4	1.5	-0.6	-1.2	0.7	0.3	-0.5	0.5	-0.3	-0.4	-0.5	0.8
High blood pressure (mother)	1.0	1.5	2.9	-1.4	1.2	-0.9	1.0	-1.7	-0.2	-0.9	-1.6	-1.7	-0.7
Body mass index (BMI)	0.2	0.8	1.9	-0.7	1.0	0.0	0.9	-1.2	-0.6	-0.2	-1.4	-1.2	-0.4
Impedance of leg (left)	0.1	0.3	0.9	0.5	-0.2	0.1	-0.5	0.9	-0.3	-0.2	0.9	0.9	-0.3
Leg predicted mass (left)	0.0	0.1	0.4	0.4	-0.0	0.6	-0.0	0.1	-0.5	0.4	-0.0	0.1	0.0
Trunk fat mass	0.0	0.1	0.3	0.1	0.3	-0.1	0.2	-0.4	-0.2	0.4	-0.5	-0.4	0.2
Waist circumference	0.2	0.7	1.3	-0.3	0.9	0.8	1.0	-1.0	-1.2	-0.3	-1.1	-0.9	-0.7
Number of incorrect matches in round	0.5	0.8	2.7	-1.6	0.5	-0.1	0.6	-1.1	0.1	-0.9	-1.1	-1.1	-0.2
Past tobacco smoking	0.1	0.2	0.5	-0.1	0.4	-0.2	0.4	-0.7	-0.1	-0.2	-0.6	-0.7	-0.3
Alcohol usually taken with meals	0.1	0.2	1.1	-0.4	-0.0	-1.1	-0.5	-0.0	0.7	0.3	0.1	-0.0	0.5
Nervous feelings	0.3	0.6	2.3	-1.5	-0.4	-0.0	0.5	-0.6	0.3	-1.5	-0.4	-0.6	-0.2
Frequency of tenseness / restlessness in last 2 weeks	0.4	0.6	1.6	-0.0	-0.9	-0.3	-0.6	0.8	1.3	-0.4	1.0	0.8	0.6
Hearing difficulty/problems with background noise	0.3	0.5	1.7	-0.6	1.2	-1.3	-0.1	-0.0	0.4	-0.7	0.0	-0.0	-0.7
Hair/balding pattern: Pattern 2	1.7	2.2	3.0	-1.1	1.1	1.4	1.7	-1.6	-1.5	-1.6	-1.5	-1.6	-1.5
Had menopause	2.7	3.4	7.3	-2.7	1.1	1.0	2.0	-2.3	-0.6	-1.7	-2.3	-2.3	-1.1
Had other major operations	0.0	0.0	0.1	0.2	-0.0	-0.4	-0.1	0.1	0.1	0.3	0.1	0.0	0.1
Forced vital capacity (FVC)	0.4	1.5	2.5	1.4	-1.6	0.6	-1.2	1.4	0.2	1.6	1.2	1.4	1.1
Heel bone mineral density (BMD) T-score, automated (right)	0.1	0.3	1.0	0.4	-0.3	-0.8	-0.4	0.0	0.5	1.0	-0.0	0.0	0.5
Ever unenthusiastic/disinterested for a whole week	0.4	0.5	1.8	-1.1	0.6	-1.0	0.1	-0.4	0.6	-1.3	-0.2	-0.5	-0.5
Qualifications: None of the above	1.2	2.6	4.9	-1.8	1.4	0.3	1.9	-2.2	-0.6	-1.2	-2.1	-2.2	-1.1
Financial difficulties in last 2 years	3.6	4.9	6.7	2.4	-2.1	-1.2	-2.4	2.6	1.5	2.4	2.5	2.6	2.0
Mouth/teeth dental problems	0.2	0.3	0.8	0.1	-0.8	-0.1	-0.4	0.2	0.9	0.3	0.4	0.3	0.9
Heart attack	0.7	0.9	3.2	-0.2	1.8	-0.0	0.6	-0.5	-1.4	-0.6	-0.7	-0.5	-1.5
Allergy	0.4	0.8	2.0	1.1	-0.1	-0.6	-1.1	1.1	0.1	1.4	0.9	1.1	0.4
Pain all over the body in last month	0.3	0.3	0.8	0.9	-0.2	0.5	-0.4	0.7	-0.5	0.7	0.5	0.7	0.1
Diabetes (self-reported)	3.3	5.0	10.2	-1.5	3.2	-0.4	2.1	-2.3	-1.7	-2.4	-2.3	-2.3	-2.9
Hayfever/allergic rhinitis (self-reported)	0.0	0.1	0.2	-0.4	0.0	-0.1	0.0	-0.3	0.0	-0.4	-0.2	-0.2	0.2
Medication: Ramipril	1.8	2.3	3.6	-1.4	1.9	-0.2	1.4	-1.7	-0.9	-1.6	-1.6	-1.7	-1.7
Medication: Simvastatin	2.1	3.1	10.9	-1.6	3.3	-1.6	0.8	-1.3	-0.9	-1.7	-1.4	-1.3	-2.4
Fluid intelligence score	0.2	0.4	1.7	0.7	-0.4	1.3	0.1	0.6	-0.7	-0.3	0.6	0.6	-0.5
Illnesses of siblings	1.3	1.8	5.1	0.7	-2.3	0.6	-1.2	1.2	1.1	1.0	1.3	1.3	1.9
Neuroticism score	2.0	4.2	7.6	-2.3	1.6	1.2	2.2	-2.1	-1.5	-2.8	-1.9	-2.1	-2.3
Weight	0.0	0.1	0.4	0.2	0.2	-0.0	-0.1	-0.1	-0.2	0.6	-0.3	-0.1	0.2
Impedance of arm (right)	0.0	0.1	0.3	0.3	-0.4	-0.1	-0.3	0.4	0.4	-0.3	0.6	0.4	0.1
Arm fat percentage (right)	0.2	0.8	1.8	-0.7	1.1	0.0	0.8	-1.2	-0.6	-0.3	-1.3	-1.2	-0.5
Trunk fat-free mass	0.0	0.1	0.2	0.4	0.1	0.3	-0.4	0.4	-0.4	0.4	0.3	0.4	-0.1
Hip circumference	0.0	0.1	0.3	0.2	0.5	0.0	0.2	-0.3	-0.6	0.4	-0.5	-0.3	-0.1
Time employed in main current job	0.3	0.4	1.7	0.6	-0.9	1.3	0.1	0.3	-0.6	0.5	0.2	0.3	0.4
Alcohol intake versus 10 years previously	0.4	0.6	1.6	-0.1	0.6	0.5	0.9	-1.1	-1.0	0.2	-1.3	-1.1	-0.2
Father’s age at death	0.7	1.0	2.3	-0.2	-1.4	-0.8	-1.1	0.8	1.3	0.4	0.8	0.8	1.5
Worrier / anxious feelings	1.1	2.1	3.2	-1.8	1.3	0.3	1.5	-1.7	-0.8	-1.6	-1.7	-1.7	-1.4
Frequency of tiredness / lethargy in last 2 weeks	0.2	0.3	0.7	0.7	-0.6	-0.1	-0.5	0.8	0.5	0.1	0.9	0.8	0.2
Falls in the last year	0.2	0.3	1.1	1.1	0.5	0.3	0.1	0.2	-0.7	0.5	0.1	0.2	-0.5
Hair/balding pattern: Pattern 3	0.4	0.6	3.0	-0.0	0.3	-1.7	-0.9	0.5	1.0	0.4	0.5	0.5	0.3
Number of live births	0.1	0.1	0.4	-0.0	-0.5	0.5	-0.1	0.1	0.3	0.6	-0.0	0.1	0.7
Forced expiratory volume in 1-second (FEV1)	0.6	2.2	3.5	1.5	-1.9	0.2	-1.6	1.8	0.7	1.5	1.7	1.8	1.4
Pulse rate	0.4	0.7	1.3	-1.1	0.4	0.7	0.9	-1.0	-1.0	-0.5	-1.2	-0.9	-0.3
Happiness	0.4	0.4	1.8	-1.0	-0.6	-0.6	0.1	-0.3	1.4	-0.4	-0.2	-0.3	0.7
Noisy workplace	1.5	1.8	2.9	1.7	-1.5	-0.1	-1.1	1.3	1.2	1.7	1.3	1.3	1.7
Qualifications: A levels/AS levels or equivalent	0.0	0.1	0.2	-0.4	0.2	0.1	-0.3	0.1	-0.5	-0.5	0.1	0.1	-0.4
Serious illness, injury or assault of a close relative in last 2 years	2.4	2.8	4.5	1.9	-1.7	-0.4	-1.9	2.1	0.9	1.3	2.1	2.1	1.4
Mouth/teeth dental problems: Dentures	0.3	0.5	1.0	-1.0	1.0	0.1	0.6	-0.6	-0.5	-0.7	-0.7	-0.6	-0.9
Asthma	0.4	0.8	1.4	-0.5	0.7	1.1	1.2	-1.0	-1.0	-0.4	-1.1	-1.0	-0.7
Medication: Ibuprofen (e.g. Nurofen)	1.4	1.8	4.1	-2.0	0.7	0.5	1.4	-1.7	-0.2	-1.7	-1.5	-1.7	-0.8
Medication: Cholesterol lowering	0.7	1.1	4.0	-0.7	2.0	-0.8	0.2	-0.4	-0.8	-0.9	-0.6	-0.5	-1.7
Depression (self-reported)	0.6	0.7	1.4	0.7	0.7	-0.4	-0.6	1.2	-0.5	-0.1	1.1	1.2	-1.1
Medication: Lansoprazole	0.6	0.7	1.8	-0.6	0.6	1.2	0.9	-0.3	-1.4	-1.0	-0.4	-0.3	-1.1
Prospective memory result	1.8	2.3	5.9	-0.8	2.4	0.7	1.3	-1.3	-2.2	-0.4	-1.6	-1.3	-1.8
Lung cancer (father)	0.2	0.3	0.7	-0.8	0.8	-0.8	-0.2	-0.2	0.2	-0.6	-0.2	-0.3	-0.4
Illnesses of mother	0.6	0.7	1.5	0.8	-0.9	0.4	-0.8	1.2	0.2	0.6	1.1	1.2	0.6
Forced expiratory volume in 1-second (FEV1), Best measure	0.3	1.0	1.7	1.3	-1.1	0.5	-1.0	1.2	0.2	1.3	1.1	1.2	0.8
Pulse wave Arterial Stiffness index	1.0	1.2	2.9	-1.5	1.1	0.2	1.0	-0.9	-0.8	-1.7	-0.8	-0.9	-1.3
Impedance of arm (left)	0.1	0.3	0.7	0.4	-0.8	0.4	-0.3	0.6	0.4	-0.1	0.7	0.6	0.4
Arm fat mass (right)	0.1	0.3	0.8	-0.2	0.8	0.1	0.5	-0.7	-0.7	0.2	-0.9	-0.7	-0.3
Trunk predicted mass	0.0	0.1	0.2	0.4	0.2	0.2	-0.5	0.5	-0.4	0.4	0.3	0.5	-0.1
Standing height	0.2	1.9	3.5	1.5	-1.2	-0.1	-1.7	1.8	0.5	1.3	1.8	1.9	1.0
Length of working week for main job	0.2	0.2	0.4	0.3	0.6	-0.1	0.5	-0.4	-0.4	0.0	-0.5	-0.5	-0.4
Exposure to tobacco smoke at home	2.1	2.3	4.7	1.8	-1.2	-0.1	-1.7	2.2	0.6	0.9	2.2	2.2	0.6
Breastfed as a baby	0.1	0.1	0.4	0.4	-0.4	0.6	0.2	0.0	-0.2	0.3	-0.1	0.0	0.1
Tense / ‘highly strung’	1.6	2.6	3.8	-1.5	1.8	0.6	1.7	-1.6	-1.8	-1.6	-1.7	-1.6	-2.0
Seen doctor (GP) for nerves, anxiety, tension or depression	0.5	0.8	3.1	-0.1	1.1	0.5	0.7	-0.2	-1.3	-1.1	-0.2	-0.2	-1.8
Hair/balding pattern: Pattern 4	0.3	0.7	2.9	-1.7	-0.5	-0.1	0.5	-0.8	0.9	-1.2	-0.6	-0.8	0.4
Birth weight of first child	0.1	0.3	0.8	0.9	0.0	0.4	-0.2	0.6	-0.7	0.4	0.6	0.6	-0.3
Peak expiratory flow (PEF)	0.1	0.2	0.5	0.7	-0.5	-0.1	-0.5	0.5	0.2	0.7	0.5	0.5	0.4
Pulse wave reflection index	1.2	1.5	3.7	-1.7	1.2	0.2	1.1	-1.2	-0.5	-1.9	-1.0	-1.2	-1.5
Ever highly irritable/argumentative for 2 days	1.6	1.9	3.9	-1.4	1.4	1.5	1.3	-0.7	-1.6	-1.9	-0.7	-0.7	-2.0
Loud music exposure frequency	1.7	1.8	3.7	1.9	-1.3	0.4	-1.2	1.8	0.4	1.1	1.7	1.8	0.8
Qualifications: O levels/GCSEs or equivalent	0.3	0.4	0.8	0.7	0.8	-0.4	-0.9	0.8	-0.6	0.5	0.6	0.8	-0.5
Mouth/teeth dental problems: Bleeding gums	0.4	0.5	1.5	0.4	-0.2	0.2	-0.6	1.2	-0.2	-0.2	1.2	1.2	-0.3
Blood clot in the leg (DVT)	0.3	0.4	0.8	-0.5	-0.1	0.6	0.8	-0.9	0.1	-0.6	-0.8	-0.9	-0.0
Medication: Paracetamol	0.0	0.0	0.1	-0.3	-0.2	-0.1	0.1	-0.2	-0.0	-0.3	-0.2	-0.2	-0.0
Headache pain in last month	0.4	0.7	1.5	0.5	0.5	-1.0	-0.9	1.2	0.2	-0.1	1.2	1.2	-0.7
Medication for cholesterol, blood pressure or diabetes	1.7	2.8	7.6	1.7	-2.8	0.9	-1.1	1.6	1.2	1.6	1.6	1.6	2.1
Glaucoma (self-reported)	0.1	0.1	0.4	0.2	-0.7	0.4	-0.1	0.2	0.1	0.1	0.2	0.2	0.3
Gout (self-reported)	0.2	0.2	0.7	-0.7	0.9	-0.4	-0.2	0.0	-0.2	-0.7	-0.0	0.0	-0.6
Hypothyroidism/myxoedema (self-reported)	0.2	0.4	2.0	-0.7	0.0	-1.4	-0.5	0.0	0.8	-0.6	0.1	0.0	0.5
Medication: Amlodipine	2.6	3.7	7.5	-2.7	1.7	-1.0	1.5	-2.5	-0.0	-2.1	-2.3	-2.5	-1.0
Medication: Ventolin 100micrograms inhaler	0.4	0.5	1.6	0.8	-1.3	0.4	-0.3	0.4	0.6	0.7	0.6	0.5	1.0
Birth weight	1.3	2.8	4.9	1.9	-2.0	0.6	-1.6	2.2	0.8	1.2	2.2	2.2	1.3
Chronic bronchitis/emphysema (mother)	0.5	0.5	0.8	0.6	-0.3	-0.9	-0.9	0.8	0.8	0.6	0.8	0.8	0.5
High blood pressure (siblings)	1.5	2.1	3.6	-1.4	1.9	-0.3	1.4	-1.4	-1.0	-1.8	-1.3	-1.5	-1.9
Forced vital capacity (FVC), Best measure	0.4	1.4	2.6	1.6	-1.4	0.8	-0.9	1.2	0.1	1.6	1.1	1.2	1.0
Body fat percentage	0.1	0.5	1.1	-0.4	0.8	0.1	0.7	-0.9	-0.6	-0.1	-1.1	-0.9	-0.3
Leg fat percentage (right)	0.3	1.2	2.3	-1.2	1.4	-0.3	1.0	-1.4	-0.8	-0.7	-1.5	-1.4	-0.8
Arm fat-free mass (right)	0.0	0.2	0.4	0.5	-0.1	0.4	-0.4	0.5	-0.4	0.6	0.4	0.5	0.1
Exposure to tobacco smoke outside home	3.8	5.1	8.1	-2.9	2.2	0.7	2.3	-2.6	-1.4	-2.5	-2.6	-2.6	-1.9
Comparative body size at age 10	1.8	4.9	9.0	2.1	-1.2	-3.0	-2.5	1.9	2.6	2.3	2.0	1.8	2.1
Number of full brothers	0.3	0.4	0.7	-0.7	0.3	0.0	0.8	-0.8	-0.0	-0.8	-0.6	-0.8	-0.4
Worry too long after embarrassment	0.9	1.5	4.6	-0.3	2.2	-0.4	1.1	-0.8	-1.2	-1.1	-0.9	-0.9	-2.1
Seen a psychiatrist for nerves, anxiety, tension or depression	0.4	0.5	1.1	0.4	0.7	-0.4	-0.3	0.9	-0.2	-0.6	0.9	0.9	-1.0
Wheeze or whistling in the chest in last year	0.6	1.1	3.9	0.4	0.8	1.6	1.1	-0.6	-2.0	-0.2	-0.8	-0.6	-1.2
Number of children fathered	1.9	2.1	4.3	1.0	-0.9	-2.1	-1.6	1.4	1.7	1.1	1.5	1.4	1.4
Reason for reducing amount of alcohol drunk: Health precaution	0.6	0.7	2.3	0.5	0.2	-1.5	-1.0	0.4	1.0	1.1	0.4	0.3	0.7
Age at first live birth	0.2	0.4	0.7	0.6	-0.5	0.8	-0.4	0.8	-0.7	0.0	0.8	0.8	-0.4
Pulse wave peak to peak time	1.2	1.4	3.4	1.6	-1.2	-0.0	-1.0	1.0	0.7	1.9	0.9	1.0	1.4
Health satisfaction	0.6	0.8	3.2	-0.8	-0.9	-1.4	-0.6	0.3	1.8	-0.1	0.4	0.3	1.1
Shortness of breath walking on level ground	0.3	0.4	1.5	-0.6	0.9	-1.2	0.3	-0.4	0.5	-0.4	-0.4	-0.5	-0.5
Qualifications: College or University degree	0.1	0.3	1.7	0.2	-0.5	1.3	0.2	0.4	-0.5	-0.5	0.4	0.4	-0.3
Eye problems/disorders: None of the above	0.3	0.4	0.8	0.3	-0.9	-0.5	-0.6	0.6	0.9	0.1	0.8	0.5	0.6
Mouth/teeth dental problems: Loose teeth	0.5	0.6	2.2	-1.5	0.5	0.2	0.7	-0.8	-0.5	-0.9	-0.8	-0.8	-0.5
Emphysema/chronic bronchitis	0.3	0.3	1.5	-0.1	1.2	-1.0	0.0	-0.0	-0.0	-0.3	-0.1	-0.1	-0.8
Medication for pain relief, constipation, heartburn	1.0	1.7	3.0	1.6	-1.5	-0.2	-1.1	1.2	0.9	1.7	1.1	1.2	1.7
Neck or shoulder pain in last month	0.1	0.2	0.3	0.2	-0.0	-0.6	-0.5	0.6	0.1	-0.2	0.6	0.6	-0.1
Medication: Blood pressure	2.4	4.2	6.9	-2.2	2.6	-0.5	1.8	-2.4	-1.1	-2.1	-2.4	-2.4	-2.0
Angina (self-reported)	0.7	0.9	2.7	-0.7	1.7	-0.7	0.4	-0.6	-0.7	-1.1	-0.5	-0.6	-1.5
Migraine (self-reported)	0.3	0.4	1.4	0.6	0.2	1.2	0.1	0.3	-1.1	-0.4	0.2	0.3	-0.9
Medication: Ibuprofen	1.5	1.8	3.8	-2.0	0.7	0.5	1.4	-1.6	-0.3	-1.8	-1.4	-1.6	-0.9
Medication: Allopurinol	0.7	1.0	3.6	-0.4	1.9	0.0	0.4	-0.4	-1.3	-0.9	-0.5	-0.4	-1.6
Medication: Omeprazole	1.0	1.1	1.8	-1.2	0.9	0.7	1.2	-1.3	-0.8	-0.9	-1.4	-1.3	-0.8
Medication: Seretide 50 evohaler	0.4	0.5	1.2	-0.4	0.2	1.0	0.7	-0.2	-0.8	-1.1	-0.0	-0.2	-1.1
Mean time to correctly identify matches	0.4	0.7	3.1	0.2	-0.0	-1.8	-0.9	0.5	1.3	0.7	0.6	0.5	0.7
Heart disease (mother)	0.3	0.4	1.8	0.5	0.1	-1.3	-0.6	0.2	0.7	0.9	0.1	0.1	0.6
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.3	0.4	1.3	1.1	-0.3	0.7	0.0	0.5	-0.2	1.1	0.3	0.5	0.3
Whole body fat mass	0.1	0.3	0.8	-0.2	0.6	0.2	0.5	-0.7	-0.5	0.2	-0.9	-0.7	-0.1
Leg fat mass (right)	0.2	0.7	1.7	-0.7	1.2	-0.1	0.7	-1.1	-0.8	-0.2	-1.3	-1.1	-0.5
Arm predicted mass (right)	0.0	0.1	0.4	0.3	-0.1	0.6	-0.2	0.3	-0.4	0.4	0.2	0.3	0.1
Pulse rate, automated reading	0.1	0.3	0.7	-0.9	-0.3	0.2	0.4	-0.6	-0.2	-0.4	-0.7	-0.6	0.3
Alcohol intake frequency.	0.2	0.5	1.0	-0.7	0.4	0.3	0.8	-1.0	-0.3	-0.4	-1.0	-1.0	-0.3
Comparative height size at age 10	0.0	0.2	0.5	0.3	-0.2	0.5	-0.5	0.4	-0.6	0.7	0.2	0.4	0.3
Number of full sisters	0.4	0.5	1.3	-1.1	0.2	-0.8	0.4	-0.9	0.6	0.2	-0.9	-0.9	0.4
Suffer from ‘nerves’	0.7	1.1	2.1	-1.3	1.4	-0.0	0.8	-0.8	-0.8	-1.5	-0.7	-0.8	-1.5
Overall health rating	0.6	1.4	2.4	-1.0	1.4	0.5	1.4	-1.1	-1.1	-1.2	-1.1	-1.1	-1.6
Chest pain or discomfort	0.1	0.1	0.5	-0.2	-0.2	-0.7	-0.0	0.1	0.7	-0.5	0.2	0.1	0.2
Had major operations	0.1	0.1	0.4	0.6	0.0	0.6	0.2	0.1	-0.5	0.5	-0.0	0.1	-0.2
Age at last live birth	1.1	1.6	3.0	1.7	-1.1	0.2	-1.3	1.6	0.0	1.6	1.4	1.6	0.7
Family relationship satisfaction	1.1	1.4	4.1	-2.0	-0.2	0.9	1.2	-1.4	-0.1	-1.3	-1.3	-1.4	-0.1
Leg pain on walking	0.1	0.1	0.5	0.0	0.3	0.3	0.1	0.4	-0.4	-0.5	0.4	0.4	-0.7
Qualifications: NVQ or HND or HNC or equivalent	0.2	0.3	0.7	0.1	-0.2	-0.3	-0.8	0.8	0.4	0.3	0.7	0.8	0.4
Commuting to job workplace: Car/motor vehicle	0.6	0.7	1.4	-0.7	0.7	1.1	0.8	-0.7	-1.2	-0.8	-0.8	-0.7	-0.8
Illness, injury, bereavement, stress in last 2 years	0.3	0.3	0.8	0.2	0.9	0.6	0.7	-0.4	-0.8	0.1	-0.6	-0.4	-0.7
Medication: Aspirin	0.7	0.9	4.7	0.3	1.0	-2.2	-1.2	0.8	0.5	0.6	0.6	0.7	-0.2
Supplements: Vitamin C	0.6	0.7	2.7	-0.1	0.2	1.6	0.6	-0.0	-1.5	-0.6	0.0	-0.0	-1.1
Knee pain experienced in last month	0.0	0.0	0.1	0.1	0.2	0.2	0.2	-0.0	-0.0	0.0	0.0	-0.1	-0.3
Hypertension (Self-reported)	3.4	9.4	16.8	-2.9	4.1	-0.3	2.9	-3.5	-2.3	-2.8	-3.6	-3.5	-3.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.4	0.5	2.5	-0.4	-0.8	1.6	0.7	-0.3	-0.4	-0.5	-0.2	-0.3	-0.2
Illnesses of father: Heart disease	1.2	1.7	2.9	1.7	0.2	-1.0	-1.6	1.7	0.1	1.4	1.5	1.7	0.1
Illnesses of siblings: Diabetes	0.7	0.8	1.6	-1.1	1.3	-0.7	0.7	-1.0	-0.4	-0.8	-1.0	-1.0	-0.9
Smoking status: Previous	0.2	0.3	0.7	-0.7	0.9	-0.0	0.3	-0.4	-0.3	-0.6	-0.4	-0.4	-0.6
Forced expiratory volume in 1-second (FEV1), predicted	1.6	3.4	6.6	2.0	-1.6	0.2	-2.0	2.6	0.6	1.4	2.6	2.6	1.0
Whole body fat-free mass	0.0	0.2	0.3	0.6	0.0	0.5	-0.3	0.4	-0.5	0.6	0.2	0.4	-0.1
Leg fat-free mass (right)	0.0	0.2	0.6	0.8	-0.1	0.7	-0.1	0.3	-0.6	0.6	0.2	0.3	0.0
Arm fat percentage (left)	0.2	0.7	1.6	-0.7	0.9	0.1	0.8	-1.2	-0.5	-0.3	-1.3	-1.2	-0.3
Average weekly red wine intake	0.1	0.1	0.2	0.1	0.3	0.1	0.3	-0.4	-0.0	-0.2	-0.4	-0.4	-0.2
Handedness (chirality/laterality): Left-handed	0.5	0.6	2.5	0.4	-1.2	0.1	-0.2	-0.2	0.7	1.1	-0.3	-0.2	1.6
Mood swings	1.2	2.2	5.7	-2.1	1.4	-0.3	1.3	-1.4	-0.1	-2.4	-1.1	-1.4	-1.7
Loneliness, isolation	0.2	0.3	1.3	-1.2	0.3	-0.6	-0.1	-0.1	0.3	-0.9	0.0	-0.1	-0.5
Long-standing illness, disability or infirmity	1.0	1.6	3.8	-0.7	1.9	0.1	1.1	-1.1	-1.4	-1.1	-1.2	-1.1	-1.7
Ever had bowel cancer screening	2.4	2.8	4.3	-0.9	2.1	0.5	1.9	-1.9	-1.5	-1.4	-1.9	-1.9	-1.9
Diabetes diagnosed by doctor	1.5	2.4	5.4	-0.7	2.2	-0.0	1.5	-1.4	-1.5	-1.7	-1.4	-1.4	-2.3
Ever had stillbirth, spontaneous miscarriage or termination	1.2	1.2	4.1	2.0	-0.1	0.7	-0.9	1.3	-0.9	1.3	1.1	1.3	-0.1
Friendships satisfaction	0.4	0.5	2.0	-1.4	-0.0	-0.0	0.5	-0.6	0.4	-1.2	-0.6	-0.7	-0.2
Qualifications: nursing, teaching	0.7	1.0	2.1	1.0	-0.4	-0.7	-1.1	1.4	0.8	0.7	1.4	1.4	0.4
Commuting to job workplace: Walk	2.2	2.4	3.8	1.6	-1.9	0.2	-1.5	1.9	1.0	1.2	1.9	1.9	1.4
Eye problems/disorders: Cataract	2.8	3.3	5.4	-2.0	2.3	0.5	1.6	-2.1	-1.5	-1.3	-2.2	-2.1	-1.6
Mouth/teeth dental problems: Mouth ulcers	0.4	0.6	1.3	-0.5	1.2	0.1	0.7	-0.9	-0.8	0.2	-1.1	-0.9	-0.6
Medication for cholesterol	1.9	2.8	9.6	0.9	-3.1	1.5	-1.1	1.7	0.9	0.9	1.8	1.8	1.8
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.8	0.9	4.2	-0.3	2.1	-0.3	0.3	-0.3	-1.2	-0.7	-0.4	-0.3	-1.6
Back pain experienced in last month	0.2	0.3	1.3	-0.2	-0.1	-1.1	-0.4	0.0	0.9	0.3	0.1	0.1	0.7
Mineral and other dietary supplements	1.2	1.6	2.7	1.2	-0.8	-1.1	-1.6	1.6	0.7	1.3	1.4	1.6	0.9
Breast cancer (self-reported)	0.3	0.3	0.7	-0.3	0.6	0.8	0.6	-0.3	-0.7	-0.5	-0.3	-0.3	-0.8
Asthma (self-reported)	0.8	1.6	2.3	-0.9	1.1	1.2	1.5	-1.5	-1.3	-0.7	-1.5	-1.5	-1.0
Osteoporosis (self-reported)	0.5	0.6	1.3	-0.7	0.1	0.9	0.9	-1.0	-0.5	0.1	-1.1	-1.0	0.1
Osteoarthritis (self-reported)	1.1	1.4	3.4	-0.3	1.2	1.4	1.2	-1.1	-1.8	-0.5	-1.2	-1.1	-1.3
Medication: Aspirin	0.8	1.1	3.9	0.7	0.8	-2.0	-1.4	1.1	0.5	0.7	1.0	1.1	-0.2
Medication: Gliclazide	0.3	0.3	1.7	-0.3	0.5	-1.3	-0.4	0.3	0.9	-0.3	0.3	0.3	0.0
Illnesses of father: None of the above (group 1)	0.1	0.1	0.3	-0.5	-0.3	0.0	0.0	-0.1	0.4	-0.2	0.0	-0.1	0.3
Smoking status: Current	2.6	4.1	7.1	1.9	-2.0	-0.5	-2.2	2.6	1.1	1.9	2.5	2.7	1.8
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.7	1.6	2.6	0.6	-1.3	-1.3	-1.6	1.2	1.6	0.7	1.3	1.2	1.3
Whole body water mass	0.0	0.1	0.3	0.5	0.1	0.4	-0.3	0.3	-0.5	0.5	0.2	0.3	-0.1
Leg predicted mass (right)	0.0	0.2	0.5	0.7	-0.1	0.6	-0.2	0.3	-0.5	0.6	0.2	0.3	0.1
Arm fat mass (left)	0.1	0.4	1.0	-0.3	0.8	0.3	0.6	-0.8	-0.7	0.1	-1.0	-0.8	-0.3
Number of self-reported non-cancer illnesses	2.4	4.2	6.0	-2.0	2.5	0.9	2.0	-2.0	-1.8	-2.3	-2.0	-2.0	-2.4
Average weekly champagne plus white wine intake	0.3	0.4	1.5	1.2	0.1	0.1	-0.4	0.4	-0.8	1.0	0.1	0.4	0.2
Miserableness	0.6	1.0	1.6	-1.2	0.5	1.2	1.1	-1.0	-0.8	-1.3	-0.9	-1.0	-1.0
Guilty feelings	0.1	0.2	0.9	-0.6	0.5	-0.9	0.0	-0.2	0.5	-0.5	-0.2	-0.3	-0.3
Wears glasses or contact lenses	2.7	3.2	5.1	-1.7	1.1	1.7	2.3	-2.1	-1.4	-1.6	-2.2	-2.1	-1.2
Ever taken oral contraceptive pill	0.9	1.0	2.7	0.4	-0.7	-1.7	-1.4	0.9	1.0	0.7	0.8	0.9	1.1
Hearing aid user	0.1	0.1	0.5	-0.5	-0.5	-0.3	-0.1	-0.3	0.4	0.3	-0.3	-0.3	0.7
Mother’s age at death	0.1	0.2	0.7	0.2	0.1	-0.8	-0.5	0.2	0.2	0.8	0.2	0.2	0.2
Financial situation satisfaction	0.5	0.6	1.2	0.4	-0.8	-0.1	-0.8	1.1	0.7	0.4	1.1	1.1	0.5
Tinnitus: Yes, now most or all of the time	0.2	0.2	0.5	-0.5	-0.6	0.1	0.2	-0.6	0.5	0.2	-0.5	-0.6	0.7
Commuting to job workplace: Public transport	0.1	0.1	0.3	-0.4	-0.3	-0.5	0.1	-0.3	0.5	-0.1	-0.3	-0.3	0.4
Eye problems/disorders: Glaucoma	0.2	0.3	0.7	0.6	-0.8	0.4	-0.3	0.4	0.1	0.6	0.4	0.4	0.6
Medication: Blood pressure	2.1	3.9	8.6	-2.2	2.9	-1.2	1.4	-2.2	-0.9	-1.9	-2.2	-2.2	-1.9
Pain type(s) experienced in last month: Hip pain	0.0	0.0	0.2	0.1	-0.5	-0.1	0.0	0.0	0.2	0.3	0.0	-0.0	0.3
Supplements: Fish oil (including cod liver oil)	0.5	0.6	1.3	-0.9	0.1	0.3	0.9	-1.1	-0.1	-0.9	-0.9	-1.1	-0.3
High cholesterol (Self-reported)	2.7	4.8	10.1	-1.5	3.0	1.1	1.9	-1.7	-2.9	-1.8	-2.0	-1.7	-3.2
Medication: Bendroflumethiazide	1.5	2.3	3.6	-1.6	1.6	0.3	1.4	-1.9	-1.2	-1.4	-1.9	-1.9	-1.3
Medication: Paracetamol	0.1	0.1	0.3	0.0	-0.2	0.5	0.2	-0.2	-0.6	-0.3	-0.2	-0.2	-0.3
Medication: Lisinopril	0.1	0.1	0.6	0.8	-0.4	0.1	-0.1	0.4	-0.3	0.2	0.5	0.4	0.0
Medication: Atorvastatin	0.6	0.8	3.4	-0.5	1.8	-0.9	0.3	-0.7	-0.5	-0.3	-0.8	-0.8	-1.0
Illnesses of father: High blood pressure	0.2	0.2	0.7	0.2	0.7	0.0	0.4	-0.3	-0.7	-0.4	-0.3	-0.3	-0.8
Alcohol drinker status: Never	1.3	1.5	3.5	-0.9	0.9	-0.1	1.5	-1.8	-0.1	-0.9	-1.8	-1.9	-0.6
Ever smoked	0.8	1.4	2.6	0.2	-1.6	-0.5	-1.3	1.3	1.2	0.8	1.3	1.3	1.6
Basal metabolic rate	0.0	0.2	0.4	0.6	0.1	0.4	-0.3	0.4	-0.5	0.6	0.2	0.4	-0.0
Leg fat percentage (left)	0.4	1.4	2.6	-1.0	1.6	-0.3	1.1	-1.4	-1.0	-0.8	-1.5	-1.4	-1.1
Arm fat-free mass (left)	0.0	0.2	0.5	0.5	0.5	0.2	-0.2	0.3	-0.7	0.4	0.1	0.3	-0.3
Number of operations (self-reported)	0.5	0.8	2.4	1.6	0.0	0.6	-0.5	0.9	-0.7	1.4	0.7	0.9	-0.1
Average weekly beer plus cider intake	0.3	0.5	1.0	0.6	-0.4	-0.3	-0.8	1.0	0.4	0.4	1.0	1.0	0.3
Irritability	2.6	4.4	7.5	-2.3	1.8	1.5	2.4	-2.0	-1.5	-2.7	-1.9	-2.0	-2.4
Risk taking	0.2	0.2	0.6	0.4	-0.6	0.2	-0.4	0.6	0.5	0.2	0.8	0.6	0.4
Ever had prostate specific antigen (PSA) test	0.5	0.6	2.4	-0.2	-0.2	-1.5	-0.8	0.3	1.3	0.5	0.3	0.3	0.9
Fractured/broken bones in last 5 years	1.1	1.4	2.7	0.6	-1.6	0.0	-1.0	1.4	1.3	0.7	1.5	1.4	1.3
Age started oral contraceptive pill	1.2	1.4	3.7	-0.2	-1.6	-1.3	-1.3	0.7	1.4	1.0	0.7	0.7	1.9
Diastolic blood pressure, automated reading	1.2	3.8	6.2	-1.5	2.5	0.4	1.9	-2.0	-1.9	-2.1	-1.9	-2.0	-2.4
Ever depressed for a whole week	0.8	1.0	3.2	0.0	-1.4	-0.6	-0.8	0.8	1.8	-0.0	1.1	0.8	1.2
Unable to work because of sickness or disability	0.4	0.5	2.2	0.2	0.8	0.7	0.4	0.0	-1.5	-0.3	-0.1	0.0	-1.4
Commuting to job workplace: Cycle	0.2	0.3	1.5	0.0	0.9	-1.2	-0.3	-0.2	-0.1	-0.0	-0.3	-0.2	-0.3
Myopia	5.2	7.6	12.4	-3.1	1.6	1.8	3.2	-3.5	-1.6	-2.8	-3.3	-3.5	-2.0
Vascular/heart problems diagnosed by doctor	4.5	12.2	23.7	3.2	-4.9	-0.1	-3.2	3.8	3.1	3.0	4.0	3.8	3.9
Cholesterol lowering medication	3.8	5.7	17.7	-1.9	4.2	-1.3	1.7	-2.2	-1.7	-1.9	-2.3	-2.2	-3.1
Medication: Omeprazole (e.g. Zanprol)	0.7	0.8	1.3	-1.1	0.4	1.1	1.0	-0.9	-0.9	-1.0	-0.9	-0.9	-0.8
Pain experienced in last month	0.1	0.2	0.8	0.4	0.8	0.3	0.1	-0.1	-0.9	0.2	-0.3	-0.1	-0.6
Supplements: Calcium	0.3	0.3	1.8	-0.2	-0.3	1.3	0.5	-0.4	-0.6	-0.2	-0.4	-0.3	-0.1
Basal cell carcinoma (self-reported)	0.3	0.3	0.9	-0.7	0.5	-0.9	-0.4	0.2	0.6	-0.8	0.4	0.2	-0.4
Heart attack/myocardial infarction (self-reported)	0.9	1.1	3.3	-0.3	1.8	0.2	0.7	-0.6	-1.6	-0.7	-0.8	-0.6	-1.6
Deep venous thrombosis (DVT) (self-reported)	0.5	0.6	1.3	-0.6	0.0	0.8	1.1	-1.1	-0.1	-0.6	-1.0	-1.1	-0.1
Heart disease (siblings)	0.0	0.0	0.2	-0.3	0.4	-0.3	0.1	-0.1	0.1	-0.1	-0.2	-0.1	-0.2
Alcohol drinker status: Previous	2.5	2.8	6.1	2.5	-0.9	-0.1	-1.8	2.3	0.2	1.3	2.4	2.3	0.5
Pack years of smoking	1.4	2.1	5.8	-0.4	2.4	0.6	1.3	-1.1	-2.0	-0.6	-1.4	-1.1	-2.0
Impedance of whole body	0.1	0.3	0.9	0.4	-0.5	0.1	-0.5	0.8	0.2	-0.3	1.0	0.9	0.0
Leg fat mass (left)	0.2	0.6	1.3	-0.5	1.1	-0.0	0.7	-0.9	-0.9	-0.1	-1.1	-0.9	-0.6
Arm predicted mass (left)	0.0	0.1	0.3	0.4	0.3	0.2	-0.4	0.4	-0.5	0.6	0.2	0.4	-0.1