Best TWAS P=1.93e-18 · Best GWAS P=3.35e-16 conditioned to 0.14
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | RP13-514E23.2 | 0.09 | 0.03 | enet | 11 | 0.04 | 2.0e-04 | 7.0 | 5.9 | 3.8e-09 | 0.62 | 0.03 | 0.92 | FALSE |
| 2 | GTEx | Artery Aorta | ARHGAP24 | 0.24 | 0.13 | enet | 8 | 0.14 | 2.2e-08 | 7.0 | 8.4 | 5.0e-17 | 0.93 | 0.01 | 0.99 | FALSE |
| 3 | GTEx | Artery Aorta | RP13-514E23.2 | 0.26 | 0.09 | lasso | 6 | 0.10 | 2.2e-06 | 7.9 | 8.3 | 9.3e-17 | 0.91 | 0.01 | 0.99 | FALSE |
| 4 | GTEx | Artery Tibial | ARHGAP24 | 0.26 | 0.19 | enet | 14 | 0.21 | 2.7e-16 | 7.9 | 8.8 | 1.9e-18 | 0.84 | 0.01 | 0.99 | TRUE |
| 5 | GTEx | Artery Tibial | RP13-514E23.2 | 0.22 | 0.16 | enet | 10 | 0.18 | 1.2e-13 | 7.9 | 8.7 | 5.3e-18 | 0.89 | 0.00 | 1.00 | FALSE |
| 6 | GTEx | Nerve Tibial | RP13-514E23.2 | 0.17 | 0.00 | lasso | 6 | 0.00 | 1.9e-01 | 8.0 | 5.5 | 3.0e-08 | 0.59 | 0.03 | 0.63 | FALSE |