# | panel | tissue | h2 | h2 se | h2 P | eQTL R2 | BLUP R2 | ENET R2 | BSLMM R2 | LASSO R2 | eQTL P | BLUP P | ENET P | BSLMM P | LASSO P |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | 0.0690 | 0.0270 | 3.5e-03 | 0.002 | 0.014 | 0.016 | 0.016 | 0.015 | 1.5e-01 | 6.4e-03 | 4.2e-03 | 4.6e-03 | 5.8e-03 |
2 | GTEx | Artery Aorta | 0.2410 | 0.0760 | 2.4e-03 | 0.132 | NA | 0.145 | NA | 0.126 | 1.0e-07 | NA | 2.2e-08 | NA | 2.1e-07 |
3 | GTEx | Artery Tibial | 0.2592 | 0.0548 | 3.1e-06 | 0.186 | NA | 0.209 | NA | 0.181 | 1.5e-14 | NA | 2.7e-16 | NA | 3.7e-14 |
4 | GTEx | Breast Mammary Tissue (Male) | 0.2394 | 0.1530 | 6.8e-02 | -0.012 | NA | 0.006 | NA | -0.013 | 7.4e-01 | NA | 2.3e-01 | NA | 9.4e-01 |
5 | GTEx | Heart Left Ventricle | 0.0902 | 0.0391 | 3.8e-03 | 0.060 | NA | 0.017 | NA | 0.033 | 3.9e-04 | NA | 4.3e-02 | NA | 7.2e-03 |
6 | GTEx | Nerve Tibial | 0.2403 | 0.0647 | 5.2e-04 | 0.039 | NA | 0.075 | NA | 0.030 | 9.5e-04 | NA | 5.6e-06 | NA | 3.3e-03 |
7 | NTR | Blood | 0.0554 | 0.0126 | 1.1e-12 | 0.050 | 0.045 | 0.054 | 0.053 | 0.055 | 1.1e-15 | 2.7e-14 | 6.1e-17 | 1.4e-16 | 2.7e-17 |
8 | YFS | Blood | 0.1655 | 0.0231 | 0.0e+00 | 0.192 | 0.178 | 0.186 | 0.192 | 0.195 | 1.3e-60 | 7.6e-56 | 1.1e-58 | 1.2e-60 | 1.1e-61 |
9 | TCGA | Brain Lower Grade Glioma | 0.0500 | 0.0229 | 7.3e-03 | -0.002 | 0.006 | -0.001 | NA | -0.002 | 7.9e-01 | 6.1e-02 | 4.5e-01 | NA | 8.2e-01 |
Trait | Avg chi2 ratio | Avg chi2 | Max chi2 | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 |
---|
Trait | Avg chi2 ratio | Avg chi2 | Max chi2 | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 |
---|---|---|---|---|---|---|---|---|---|---|---|---|
Systolic blood pressure, automated reading | 6.1 | 17.7 | 76.7 | -2.3 | 8.4 | 8.8 | -1.0 | 0.1 | 2.0 | 0.7 | 0.5 | 1.2 |
Heel T-Score | 6.0 | 47.6 | 179.6 | -1.8 | 13.4 | 13.1 | -1.8 | 1.0 | 6.6 | -0.8 | -0.8 | 4.9 |
Systolic Blood Pressure | 5.6 | 28.1 | 112.4 | -3.0 | 10.5 | 10.6 | -0.4 | 1.7 | 2.8 | 0.4 | 0.1 | 3.2 |
Heel bone mineral density (BMD) T-score, automated (left) | 4.6 | 10.5 | 34.3 | -1.0 | 5.9 | 5.5 | -0.8 | 0.5 | 3.9 | -0.4 | -0.6 | 3.5 |
Heel bone mineral density (BMD) T-score, automated (right) | 4.5 | 10.2 | 33.2 | -1.1 | 5.8 | 5.5 | -0.7 | 0.1 | 3.6 | 0.2 | 0.1 | 3.8 |
Illnesses of father: High blood pressure | 4.0 | 5.0 | 18.0 | -0.7 | 4.2 | 4.1 | -0.2 | 1.2 | 1.7 | 0.7 | 0.6 | 2.0 |
Bipolar Disorder (2011) | 3.9 | 3.8 | 11.9 | -3.4 | 0.4 | 1.1 | -2.5 | 0.4 | -1.3 | 2.5 | 2.2 | 1.3 |
High blood pressure (mother) | 2.8 | 3.9 | 11.1 | -3.3 | 1.0 | 2.0 | -2.0 | -0.6 | -1.2 | -1.0 | -1.2 | 3.3 |
Alcohol intake versus 10 years previously | 2.5 | 3.8 | 15.9 | 4.0 | 0.1 | -0.2 | -0.3 | -3.0 | 0.1 | -0.8 | -0.7 | -2.8 |
Ever had hysterectomy (womb removed) | 2.4 | 2.7 | 11.0 | -0.3 | -1.6 | -1.8 | -2.4 | -3.3 | -0.7 | 0.4 | 0.1 | -1.1 |
Time employed in main current job | 2.3 | 2.6 | 7.2 | -0.7 | 1.9 | 1.3 | -0.2 | -0.1 | 2.6 | 1.5 | 1.2 | -2.7 |
High blood pressure (siblings) | 2.3 | 3.4 | 12.4 | -0.3 | 3.0 | 3.5 | -0.9 | -2.2 | 0.3 | 0.9 | 0.9 | 1.2 |
Illnesses of mother | 2.2 | 2.8 | 8.7 | 3.0 | -1.7 | -2.4 | 1.5 | -0.3 | 1.0 | 0.5 | 0.6 | -1.8 |
Diabetes (father) | 2.0 | 2.5 | 6.6 | 2.6 | 1.0 | 0.3 | -0.3 | -1.6 | 0.1 | 2.3 | 2.6 | -0.9 |
Illnesses of siblings | 2.0 | 2.8 | 9.9 | -0.3 | -2.8 | -3.1 | -0.5 | 1.3 | -1.8 | -0.9 | -0.9 | -0.7 |
Loud music exposure frequency | 2.0 | 2.2 | 6.4 | 0.3 | -2.5 | -2.5 | 1.4 | 1.5 | 1.3 | -0.3 | -0.1 | 0.9 |
High blood pressure | 1.9 | 5.3 | 23.0 | -0.7 | 4.4 | 4.8 | -0.4 | -0.1 | 1.0 | 0.6 | 0.5 | 1.7 |
Birth weight of first child | 1.9 | 3.4 | 9.7 | 1.1 | -2.6 | -3.0 | 1.2 | -1.3 | 0.8 | -0.2 | -0.3 | -3.1 |
Ever had stillbirth, spontaneous miscarriage or termination | 1.9 | 2.0 | 4.9 | -1.9 | 0.9 | 0.7 | -0.2 | -0.6 | 0.2 | -1.9 | -2.2 | 1.9 |
Basal cell carcinoma (self-reported) | 1.9 | 2.2 | 6.7 | -1.7 | 0.0 | 0.6 | 1.6 | 1.0 | -0.4 | -2.6 | -2.5 | -0.4 |
Cardiovascular Disease | 1.8 | 6.0 | 24.7 | -1.0 | 4.8 | 5.0 | 0.1 | 0.4 | 1.8 | 0.5 | 0.4 | 1.4 |
Number of children fathered | 1.8 | 2.1 | 7.3 | 0.3 | 2.3 | 2.7 | -1.1 | -1.6 | 1.4 | 0.6 | 0.4 | -0.1 |
Heart disease (mother) | 1.8 | 2.2 | 5.8 | -0.2 | 0.7 | 1.0 | -2.3 | -0.9 | -2.4 | -1.3 | -1.5 | 1.7 |
Number of operations (self-reported) | 1.8 | 2.7 | 10.5 | 0.9 | -3.2 | -3.2 | 0.8 | -0.8 | -0.1 | -0.3 | -0.5 | -1.0 |
Leg fat-free mass (left) | 1.7 | 9.1 | 29.3 | 1.2 | -5.2 | -5.4 | 0.3 | -0.1 | -3.1 | -1.3 | -0.7 | -3.5 |
Leg predicted mass (left) | 1.7 | 9.1 | 29.7 | 1.1 | -5.3 | -5.5 | 0.2 | -0.1 | -3.1 | -1.3 | -0.8 | -3.3 |
Had other major operations | 1.7 | 2.1 | 7.2 | 0.5 | -2.7 | -2.6 | 0.7 | -1.2 | -0.5 | 0.4 | 0.5 | -1.4 |
Ever unenthusiastic/disinterested for a whole week | 1.7 | 2.1 | 4.5 | 0.9 | -2.0 | -2.1 | 1.0 | 1.8 | -1.0 | 0.8 | 1.3 | -1.3 |
Allergy | 1.7 | 4.0 | 14.6 | -0.8 | 3.4 | 3.8 | 1.7 | 1.0 | 2.3 | 0.1 | 0.3 | 0.2 |
Hypertension (Self-reported) | 1.7 | 4.7 | 19.8 | -0.4 | 4.2 | 4.5 | -0.2 | -0.0 | 0.7 | 1.1 | 1.0 | 1.4 |
Forced expiratory volume in 1-second (FEV1), predicted | 1.7 | 3.5 | 10.1 | -1.3 | -3.2 | -3.1 | -0.0 | 1.0 | -2.8 | -0.9 | -0.8 | 0.4 |
Leg fat-free mass (right) | 1.7 | 9.2 | 29.8 | 0.8 | -5.3 | -5.5 | 0.4 | 0.3 | -3.0 | -1.5 | -1.0 | -3.4 |
Leg predicted mass (right) | 1.7 | 9.2 | 29.8 | 0.9 | -5.3 | -5.5 | 0.4 | 0.2 | -3.0 | -1.5 | -0.9 | -3.4 |
Diastolic blood pressure, automated reading | 1.7 | 5.4 | 21.8 | -1.6 | 4.5 | 4.7 | 0.1 | 0.7 | -0.9 | -0.5 | -0.6 | 1.2 |
Pain all over the body in last month | 1.6 | 1.7 | 5.0 | 0.7 | -0.3 | -0.5 | 2.0 | 1.1 | -0.2 | 2.0 | 2.2 | 0.2 |
Pulse rate | 1.6 | 2.7 | 8.2 | -1.3 | -2.3 | -1.8 | 0.4 | 1.4 | -2.9 | -0.3 | -0.7 | 1.8 |
Medication: Amlodipine | 1.6 | 2.3 | 6.0 | -2.3 | 1.5 | 2.0 | -2.4 | -1.3 | 0.2 | -0.5 | -0.6 | 0.8 |
Exposure to tobacco smoke outside home | 1.6 | 2.1 | 4.7 | -1.9 | -0.4 | -0.8 | 1.0 | 1.7 | 1.3 | 1.8 | 2.2 | 0.6 |
Shortness of breath walking on level ground | 1.6 | 1.9 | 9.1 | 0.8 | -1.1 | -1.0 | -1.1 | -1.6 | -3.0 | -1.1 | -0.8 | -0.1 |
Whole body fat-free mass | 1.6 | 9.2 | 29.6 | 0.6 | -5.3 | -5.4 | 0.9 | 0.6 | -2.5 | -1.6 | -1.1 | -3.6 |
Whole body water mass | 1.6 | 9.1 | 28.3 | 0.4 | -5.2 | -5.3 | 0.9 | 0.6 | -2.5 | -1.8 | -1.2 | -3.7 |
Type 2 Diabetes (T2D) (2012) | 1.5 | 1.7 | 4.8 | -1.9 | 0.8 | 1.0 | -0.7 | -0.6 | -0.5 | 1.9 | 2.2 | -0.5 |
Trunk fat-free mass | 1.5 | 8.3 | 26.4 | 0.3 | -5.1 | -5.1 | 1.1 | 0.7 | -2.0 | -1.8 | -1.3 | -3.4 |
Mouth/teeth dental problems: Dentures | 1.5 | 2.6 | 12.9 | 1.6 | 0.0 | 0.0 | -1.7 | -3.6 | 1.4 | -0.3 | -0.3 | -1.6 |
Lung cancer (father) | 1.5 | 1.8 | 5.6 | -0.9 | -1.5 | -1.3 | -2.4 | -2.0 | -0.9 | -0.6 | -0.6 | -0.6 |
Worry too long after embarrassment | 1.5 | 2.5 | 7.1 | 0.0 | -1.1 | -0.8 | 0.9 | 0.9 | -2.2 | -2.7 | -2.4 | -0.9 |
Average weekly red wine intake | 1.5 | 2.2 | 5.1 | -1.3 | -0.8 | -0.2 | -2.0 | -0.7 | -0.8 | 2.2 | 2.2 | 1.5 |
Wears glasses or contact lenses | 1.5 | 1.7 | 4.7 | 0.4 | 1.1 | 1.4 | -2.1 | -2.2 | -1.2 | -0.6 | -0.8 | 0.6 |
Alcohol drinker status: Never | 1.5 | 1.8 | 5.2 | 1.7 | 0.0 | 0.1 | 1.2 | 1.0 | 0.4 | 1.9 | 2.3 | -1.3 |
Basal metabolic rate | 1.5 | 8.4 | 25.7 | 0.4 | -5.0 | -5.1 | 0.9 | 0.7 | -2.5 | -1.7 | -1.1 | -3.7 |
Ever had prostate specific antigen (PSA) test | 1.5 | 1.7 | 4.4 | -2.1 | -1.1 | -0.6 | -0.0 | 0.8 | 0.4 | 1.7 | 1.7 | 1.7 |
Commuting to job workplace: Cycle | 1.5 | 1.8 | 5.1 | 0.4 | -0.5 | 0.3 | -2.1 | -0.3 | -1.2 | -2.2 | -2.3 | 0.4 |
Arm predicted mass (left) | 1.5 | 7.5 | 22.1 | -0.1 | -4.6 | -4.7 | 1.1 | 0.9 | -1.9 | -2.0 | -1.4 | -3.6 |
Coronary Artery Disease (CAD) | 1.4 | 1.7 | 4.2 | -2.1 | -0.1 | -0.1 | -1.3 | 0.8 | -0.4 | -1.7 | -1.8 | 1.5 |
Diabetes (mother) | 1.4 | 1.8 | 3.6 | -1.5 | -1.4 | -0.9 | 0.8 | 1.7 | -1.1 | -1.3 | -0.9 | -1.9 |
Trunk predicted mass | 1.4 | 8.3 | 26.2 | 0.2 | -5.1 | -5.1 | 1.2 | 0.7 | -2.0 | -1.8 | -1.3 | -3.4 |
Length of working week for main job | 1.4 | 1.6 | 4.0 | -1.9 | 0.6 | 0.3 | -2.0 | -1.7 | 1.5 | 0.7 | 0.6 | -0.5 |
Medication: Bendroflumethiazide | 1.4 | 2.1 | 8.9 | -1.1 | 3.0 | 2.9 | 0.8 | 0.2 | -0.0 | -0.1 | 0.1 | 0.6 |
Arm fat-free mass (left) | 1.4 | 7.1 | 21.0 | -0.2 | -4.4 | -4.6 | 1.0 | 0.9 | -1.9 | -1.8 | -1.3 | -3.7 |
Vascular/heart problems diagnosed by doctor | 1.4 | 3.7 | 17.8 | 0.6 | -3.5 | -4.2 | 0.3 | -0.0 | -0.8 | -0.2 | -0.2 | -1.5 |
Deep venous thrombosis (DVT) (self-reported) | 1.4 | 1.8 | 7.2 | 0.6 | -2.4 | -2.7 | 0.7 | -0.1 | -0.2 | 0.6 | 0.8 | -1.4 |
Alcohol drinker status: Previous | 1.4 | 1.6 | 4.0 | -1.1 | -1.6 | -1.6 | 0.0 | 2.0 | -1.9 | 0.0 | -0.2 | 0.3 |
Height | 1.3 | 24.9 | 97.0 | 0.6 | -9.8 | -9.1 | 0.7 | 0.0 | -2.9 | -3.8 | -3.3 | -3.3 |
Frequency of depressed mood in last 2 weeks | 1.3 | 1.8 | 3.2 | -1.6 | 1.0 | 1.2 | 1.8 | 1.3 | -0.1 | -1.5 | -1.3 | 1.4 |
Multivitamins +/- minerals | 1.3 | 1.7 | 3.6 | -1.3 | -1.0 | -1.2 | 0.3 | 1.7 | -1.3 | 1.2 | 1.0 | 1.9 |
Medication: Levothyroxine sodium | 1.3 | 2.2 | 6.1 | 0.7 | -2.5 | -2.5 | -0.1 | 0.9 | -2.0 | 0.1 | 0.2 | -1.5 |
Forced expiratory volume in 1-second (FEV1), Best measure | 1.3 | 4.1 | 13.6 | -1.3 | -0.7 | -1.3 | 2.9 | 3.7 | 1.1 | -2.5 | -2.0 | 0.2 |
Blood clot in the leg (DVT) | 1.3 | 1.6 | 5.8 | 0.3 | -2.1 | -2.4 | 1.2 | 0.3 | 0.0 | 0.9 | 1.0 | -1.0 |
Arm fat-free mass (right) | 1.3 | 6.8 | 19.2 | -0.4 | -4.4 | -4.4 | 0.4 | 1.0 | -2.3 | -1.7 | -1.1 | -3.5 |
Number of full sisters | 1.3 | 1.6 | 4.9 | 0.9 | -1.4 | -1.4 | 2.2 | 1.8 | -0.8 | -0.6 | -0.7 | 0.0 |
Forced expiratory volume in 1-second (FEV1), predicted percentage | 1.3 | 2.8 | 6.8 | -0.6 | 2.0 | 1.2 | 1.9 | 2.6 | 1.8 | -1.8 | -1.6 | 0.4 |
Medication: Lisinopril | 1.3 | 1.7 | 5.6 | -0.6 | 2.1 | 2.4 | 0.1 | 0.8 | 1.8 | 0.4 | 0.8 | 0.6 |
Myopia | 1.3 | 1.8 | 6.2 | -1.3 | -0.7 | -0.4 | -2.1 | -0.2 | -2.5 | 1.3 | 1.1 | 0.9 |
Crohns Disease (2012) | 1.2 | 1.9 | 4.1 | 0.0 | -2.0 | -2.0 | 1.5 | 1.8 | -1.5 | 0.6 | 0.8 | -0.4 |
HDL Cholesterol | 1.2 | 2.1 | 5.0 | 2.2 | -1.3 | -2.1 | 1.5 | 1.8 | -1.2 | 0.1 | -0.3 | 0.2 |
Hayfever, allergic rhinitis or eczema | 1.2 | 2.5 | 11.4 | 0.7 | -2.9 | -3.4 | -1.2 | -0.3 | -1.0 | 0.4 | 0.2 | 0.0 |
Hayfever/allergic rhinitis (self-reported) | 1.2 | 1.5 | 4.1 | 1.2 | -2.0 | -1.8 | -0.0 | 0.6 | -1.4 | -1.0 | -1.4 | 0.4 |
Forced expiratory volume in 1-second (FEV1) | 1.2 | 4.1 | 9.7 | -1.3 | 0.0 | -0.7 | 2.5 | 2.9 | 1.8 | -3.1 | -2.8 | 0.0 |
Medication: Blood pressure | 1.2 | 2.2 | 8.2 | -0.0 | 2.8 | 2.9 | -0.1 | 0.5 | -0.2 | 1.3 | 1.0 | 0.3 |
Medication: Omeprazole | 1.2 | 1.4 | 5.4 | -1.0 | 0.8 | 0.7 | 1.8 | 2.3 | -1.1 | -0.2 | -0.0 | -1.0 |
Arm predicted mass (right) | 1.2 | 6.2 | 18.1 | -0.3 | -4.1 | -4.3 | 0.2 | 0.7 | -2.1 | -1.7 | -1.2 | -3.4 |
Medication: Aspirin | 1.2 | 1.6 | 4.4 | -0.1 | 1.8 | 2.1 | -1.3 | -1.7 | 1.0 | 0.3 | 0.7 | 0.3 |
Osteoarthritis (self-reported) | 1.2 | 1.6 | 4.2 | -0.8 | 1.3 | 1.3 | 1.5 | 1.1 | 0.3 | 1.1 | 1.3 | -2.0 |
Average weekly champagne plus white wine intake | 1.2 | 1.7 | 6.2 | -2.5 | -0.9 | -0.3 | 0.5 | 0.8 | -2.0 | -1.5 | -1.1 | -0.2 |
High cholesterol (Self-reported) | 1.2 | 2.1 | 6.9 | 1.3 | 2.4 | 2.6 | 0.8 | 0.2 | 1.7 | 0.2 | 0.3 | -0.6 |
Ever smoked | 1.2 | 2.0 | 5.8 | 1.2 | -1.9 | -1.6 | -1.2 | -2.4 | 0.0 | -1.3 | -1.4 | 0.1 |
Heart attack/myocardial infarction (self-reported) | 1.2 | 1.6 | 4.5 | -0.5 | -2.0 | -1.6 | 2.1 | 1.1 | 0.2 | 0.2 | 0.3 | -1.4 |
Waist Hip Ratio (WHR) | 1.1 | 4.8 | 12.4 | 0.1 | 3.1 | 2.7 | -1.2 | -2.9 | 1.5 | -0.7 | -0.9 | 3.5 |
Lung FVC | 1.1 | 5.5 | 18.7 | -0.2 | 2.7 | 2.0 | 3.2 | 3.0 | 4.3 | -0.6 | -0.2 | 0.4 |
Heart attack | 1.1 | 1.4 | 4.6 | -0.7 | -1.6 | -1.1 | 2.1 | 1.4 | 0.5 | 0.3 | 0.5 | -1.1 |
Pulse wave Arterial Stiffness index | 1.1 | 1.3 | 6.9 | -1.2 | -0.1 | 0.0 | -1.3 | -2.6 | 1.0 | 0.4 | 0.4 | 0.6 |
Pulse wave reflection index | 1.1 | 1.3 | 4.7 | 0.0 | 0.3 | 0.2 | -1.3 | -2.2 | 0.9 | 0.9 | 1.2 | -1.4 |
Mouth/teeth dental problems: Bleeding gums | 1.1 | 1.4 | 2.9 | -0.2 | 0.7 | 0.7 | -0.0 | 0.9 | 1.7 | 1.7 | 1.7 | 1.3 |
Glaucoma (self-reported) | 1.1 | 1.3 | 3.7 | -1.3 | 1.0 | 1.9 | -1.1 | -1.5 | 1.0 | -0.6 | -0.5 | -0.1 |
Pulse wave peak to peak time | 1.1 | 1.3 | 6.2 | 1.3 | -0.0 | -0.1 | 1.4 | 2.5 | -1.0 | -0.3 | -0.3 | -0.7 |
Commuting to job workplace: Car/motor vehicle | 1.1 | 1.3 | 5.3 | 0.8 | 2.3 | 2.2 | -0.7 | -0.4 | 0.5 | -0.0 | 0.0 | 0.2 |
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) | 1.1 | 1.2 | 6.5 | -1.0 | 1.3 | 0.7 | 0.9 | 2.5 | 0.4 | -0.1 | -0.0 | -0.7 |
Medication: Paracetamol | 1.1 | 1.7 | 4.7 | 1.2 | 1.6 | 1.1 | -0.1 | -0.3 | 1.1 | 1.1 | 1.5 | -2.2 |
Age started oral contraceptive pill | 1.1 | 1.4 | 4.9 | 2.2 | 0.8 | 1.3 | -0.5 | -1.2 | 0.9 | 0.8 | 1.0 | -0.8 |
Heart disease (siblings) | 1.1 | 1.3 | 3.8 | 0.3 | 0.8 | 1.0 | -0.2 | -2.0 | 1.7 | 1.1 | 0.9 | -1.1 |
Schizophrenia vs Biploar Disorder | 1.0 | 1.3 | 4.5 | 0.3 | -0.2 | 0.0 | -0.5 | -0.8 | 1.1 | 2.1 | 1.7 | -1.5 |
Reaction Time | 1.0 | 1.8 | 7.8 | -0.1 | -0.0 | -0.1 | -1.6 | -2.8 | -1.3 | -0.5 | -0.5 | 1.9 |
Body Mass Index (BMI) (2010) | 1.0 | 1.4 | 3.5 | 1.0 | 1.2 | 0.9 | 0.5 | 0.3 | 0.9 | -1.6 | -1.6 | 1.9 |
Fasting Glucose | 1.0 | 1.2 | 3.3 | 0.7 | -1.3 | -1.8 | 1.4 | -1.4 | -1.1 | -0.1 | 0.1 | -0.8 |
Lupus | 1.0 | 1.6 | 5.2 | -1.4 | 0.6 | 0.9 | -1.2 | 0.2 | -0.8 | -2.3 | -2.0 | -0.0 |
Blood Platelet Count | 1.0 | 12.1 | 36.6 | 3.8 | 6.0 | 5.7 | -1.3 | -4.0 | 2.2 | -0.6 | -0.9 | 1.4 |
Other serious medical condition/disability diagnosed by doctor | 1.0 | 1.3 | 2.7 | 0.9 | 0.5 | 0.3 | -0.6 | -1.3 | -1.5 | 1.6 | 1.5 | -1.1 |
Impedance of leg (left) | 1.0 | 4.9 | 12.8 | -2.4 | 3.3 | 3.6 | -0.1 | 0.2 | 1.6 | -0.4 | -0.7 | 3.3 |
Hair/balding pattern: Pattern 2 | 1.0 | 1.2 | 4.9 | 0.4 | -1.3 | -1.1 | -0.6 | -1.4 | -0.6 | -0.1 | 0.3 | -2.2 |
Had menopause | 1.0 | 1.2 | 5.2 | 0.3 | 0.3 | 0.8 | -1.1 | -2.3 | -0.1 | 1.2 | 1.3 | -1.0 |
Medication: Cholesterol lowering | 1.0 | 1.6 | 3.0 | 1.6 | 1.7 | 1.6 | -0.4 | 0.1 | 1.7 | 1.3 | 1.0 | 0.4 |
Standing height | 1.0 | 9.8 | 35.5 | -1.0 | -6.0 | -5.6 | -0.2 | -0.5 | -2.7 | -2.4 | -2.2 | -1.3 |
Medication for cholesterol, blood pressure or diabetes | 1.0 | 1.7 | 4.9 | -1.0 | -2.2 | -2.1 | -0.4 | -0.8 | -0.9 | -1.4 | -1.1 | -0.2 |
Gout (self-reported) | 1.0 | 1.4 | 3.5 | -0.2 | -0.3 | 0.2 | -0.7 | -1.5 | -1.1 | 1.5 | 1.7 | -1.9 |
Forced vital capacity (FVC), Best measure | 1.0 | 3.7 | 8.2 | -0.7 | -1.3 | -1.8 | 2.7 | 2.9 | 1.6 | -2.4 | -1.9 | 0.5 |
Supplements: Vitamin C | 1.0 | 1.2 | 6.8 | 2.6 | 0.8 | 0.4 | 0.6 | -0.2 | -0.8 | -0.0 | -0.2 | -1.5 |
Loneliness, isolation | 1.0 | 1.3 | 6.9 | -2.6 | -1.4 | -1.4 | 0.6 | 0.2 | 0.4 | 0.2 | 0.3 | -0.8 |
Eye problems/disorders: Cataract | 1.0 | 1.1 | 4.0 | 0.8 | -1.0 | -0.8 | -0.1 | 0.2 | 2.0 | 1.3 | 1.4 | 0.5 |
Breast cancer (self-reported) | 1.0 | 1.2 | 7.0 | 0.2 | -1.4 | -1.2 | 0.7 | -0.5 | -0.2 | -0.2 | -0.1 | -2.6 |
Illnesses of father: None of the above (group 1) | 1.0 | 1.3 | 4.4 | -0.3 | -2.1 | -1.7 | -0.8 | -1.4 | -0.6 | -0.1 | -0.0 | -1.0 |
Tinnitus: Yes, now most or all of the time | 1.0 | 1.1 | 7.3 | 2.7 | 0.7 | 0.3 | -0.5 | -1.1 | 0.6 | -0.4 | -0.6 | -0.4 |
Bipolar Disorder or Schizophrenia | 0.9 | 2.1 | 8.6 | -2.9 | -0.4 | 0.2 | -1.7 | 0.6 | -0.9 | 0.4 | 0.3 | 2.4 |
Crohns Disease (2017) | 0.9 | 2.0 | 6.0 | -0.8 | -2.4 | -1.9 | 0.5 | 1.9 | -1.9 | 0.2 | 0.3 | -0.5 |
Schizophrenia (2014) | 0.9 | 1.9 | 8.3 | -2.9 | -0.7 | -0.1 | -1.9 | -0.2 | -0.3 | 1.1 | 0.8 | 1.7 |
Ulcerative Colitis | 0.9 | 1.3 | 3.2 | 0.0 | 0.8 | 0.7 | 0.9 | 1.3 | 1.5 | 1.8 | 1.5 | 0.3 |
Respiratory disease | 0.9 | 2.1 | 6.9 | 0.5 | -2.4 | -2.6 | -0.5 | -0.9 | -0.7 | -1.3 | -1.3 | 0.9 |
Sensitivity / hurt feelings | 0.9 | 1.5 | 7.5 | -2.7 | -0.3 | -0.3 | 1.0 | 0.4 | -1.2 | -1.4 | -1.0 | 0.5 |
Impedance of leg (right) | 0.9 | 4.1 | 11.5 | -1.8 | 3.1 | 3.2 | -0.3 | -0.3 | 1.3 | -0.0 | -0.5 | 3.4 |
Bilateral oophorectomy (both ovaries removed) | 0.9 | 1.1 | 3.0 | -0.4 | 0.5 | 0.6 | -1.2 | -1.4 | 1.1 | -0.5 | -1.1 | 1.7 |
Medication: Atenolol | 0.9 | 1.1 | 4.5 | -1.0 | -0.6 | -0.3 | -0.8 | -0.5 | -0.4 | 1.6 | 2.1 | -0.1 |
Forced vital capacity (FVC) | 0.9 | 3.4 | 7.7 | -0.7 | -0.8 | -1.2 | 2.1 | 2.3 | 1.9 | -2.8 | -2.5 | -0.1 |
Medication: Simvastatin | 0.9 | 1.4 | 4.3 | 2.1 | 1.6 | 1.5 | 0.2 | -0.1 | 1.3 | 0.5 | 0.7 | -0.9 |
Number of live births | 0.9 | 1.3 | 3.0 | -0.7 | -1.3 | -1.3 | 1.4 | 0.4 | 0.1 | 1.7 | 1.4 | -0.9 |
Peak expiratory flow (PEF) | 0.9 | 2.0 | 5.2 | -0.9 | 0.9 | 0.2 | 1.6 | 2.3 | 1.2 | -2.0 | -1.8 | 0.0 |
Ever highly irritable/argumentative for 2 days | 0.9 | 1.1 | 5.5 | 0.7 | -1.1 | -1.1 | -0.9 | -0.4 | -0.7 | -0.0 | 0.0 | -2.3 |
Birth weight | 0.9 | 1.9 | 6.0 | 0.7 | -2.4 | -2.5 | -0.7 | -1.4 | -0.1 | -0.6 | -0.5 | -1.2 |
Reason for reducing amount of alcohol drunk: Health precaution | 0.9 | 1.1 | 2.9 | -1.5 | 0.3 | 0.1 | 1.0 | 1.7 | -0.4 | -0.4 | -0.5 | 1.6 |
Mouth/teeth dental problems: Loose teeth | 0.9 | 1.0 | 2.5 | 0.7 | -0.6 | -1.1 | 0.9 | 1.0 | -0.2 | 1.3 | 1.6 | -1.1 |
Mean time to correctly identify matches | 0.9 | 1.7 | 7.4 | 0.4 | -0.2 | -0.1 | -1.8 | -2.7 | -1.2 | -0.1 | -0.2 | 1.6 |
Qualifications: NVQ or HND or HNC or equivalent | 0.9 | 1.0 | 3.2 | -0.1 | -1.7 | -1.8 | 0.9 | 1.1 | 1.0 | 0.2 | 0.0 | -0.3 |
Long-standing illness, disability or infirmity | 0.9 | 1.3 | 3.5 | 1.3 | 0.8 | 0.3 | -0.1 | -1.5 | -0.7 | 1.5 | 1.9 | -1.0 |
Qualifications: nursing, teaching | 0.9 | 1.4 | 8.4 | 1.0 | -0.5 | -0.5 | -0.7 | -2.9 | -1.3 | -0.1 | -0.3 | -0.0 |
Mother’s age at death | 0.9 | 1.1 | 3.0 | -1.2 | 1.2 | 1.2 | 0.6 | -0.1 | -0.3 | -1.2 | -1.7 | 1.1 |
Fractured/broken bones in last 5 years | 0.9 | 1.2 | 4.9 | 1.1 | -0.8 | -1.3 | 2.2 | 1.3 | -0.5 | -0.2 | -0.4 | -0.6 |
Ovarian Cancer | 0.8 | 1.1 | 2.9 | 1.3 | 1.1 | 0.6 | -0.4 | -0.5 | -0.2 | 1.7 | 1.3 | -1.4 |
Hypothyroidism (self reported) | 0.8 | 1.9 | 6.2 | 0.3 | -2.5 | -2.4 | 0.1 | 0.7 | -1.5 | -1.0 | -0.8 | -1.1 |
Average weekly spirits intake | 0.8 | 1.0 | 3.9 | 0.1 | 0.4 | 0.3 | -2.0 | -1.9 | -0.4 | -0.5 | -0.3 | -1.0 |
Supplements: Zinc | 0.8 | 0.9 | 4.6 | -0.6 | -0.8 | -0.5 | -0.6 | -0.3 | 2.1 | 0.8 | 0.7 | -0.9 |
Severe depression (siblings) | 0.8 | 0.8 | 3.4 | -0.9 | 1.8 | 1.5 | -0.4 | -0.9 | 0.2 | 0.2 | 0.1 | -0.2 |
Hearing difficulty/problems with background noise | 0.8 | 1.3 | 4.2 | 0.7 | -0.7 | -0.1 | 0.6 | -0.5 | 2.0 | 1.8 | 1.6 | 0.4 |
Neuroticism score | 0.8 | 1.7 | 5.0 | -2.2 | -0.4 | -0.1 | -0.2 | -0.0 | -0.9 | -2.2 | -1.8 | 1.0 |
Weight | 0.8 | 3.8 | 10.6 | 0.4 | -2.8 | -2.9 | 0.2 | 0.2 | -2.4 | -1.1 | -0.7 | -3.3 |
Hip circumference | 0.8 | 3.3 | 10.6 | -0.4 | -1.9 | -2.2 | 0.8 | 0.8 | -2.4 | -1.5 | -1.0 | -3.3 |
Hair/balding pattern: Pattern 3 | 0.8 | 1.2 | 2.5 | -1.4 | 1.0 | 1.0 | -1.4 | 0.7 | -0.9 | 0.8 | 0.5 | 1.6 |
Depression (self-reported) | 0.8 | 0.9 | 2.3 | -1.5 | 1.0 | 0.7 | -1.4 | -1.3 | -0.3 | -0.6 | -0.5 | -0.2 |
Hypothyroidism/myxoedema (self-reported) | 0.8 | 1.5 | 3.8 | 1.5 | -1.8 | -1.6 | -0.5 | 0.7 | -1.9 | -0.0 | 0.3 | -0.8 |
Seen a psychiatrist for nerves, anxiety, tension or depression | 0.8 | 1.1 | 3.1 | 0.1 | -0.8 | -0.9 | -0.4 | -0.1 | 1.4 | 1.5 | 1.8 | -0.8 |
Chest pain or discomfort | 0.8 | 1.2 | 2.8 | 0.5 | 1.2 | 1.6 | -1.1 | -0.3 | 0.2 | -1.7 | -1.5 | 0.4 |
Had major operations | 0.8 | 1.0 | 2.3 | 1.0 | -1.1 | -1.1 | -0.8 | -0.4 | 0.6 | 1.5 | 1.4 | -0.3 |
Knee pain experienced in last month | 0.8 | 1.3 | 3.3 | 0.5 | 0.7 | -0.2 | -0.6 | 0.7 | 0.6 | 1.7 | 1.8 | -1.7 |
Illnesses of father: Heart disease | 0.8 | 1.1 | 3.0 | -0.4 | 0.9 | 1.0 | 1.7 | 1.1 | -0.2 | -1.0 | -1.4 | 0.8 |
Commuting to job workplace: Walk | 0.8 | 0.8 | 2.3 | 0.5 | 0.1 | -0.4 | -0.5 | -1.5 | 0.7 | 1.4 | 1.4 | -0.3 |
Osteoporosis (self-reported) | 0.8 | 1.0 | 3.2 | 0.3 | 0.2 | -0.2 | -0.6 | 0.6 | 0.5 | -1.8 | -1.7 | 1.4 |
Medication: Aspirin | 0.8 | 1.0 | 3.3 | -0.6 | 1.5 | 1.8 | -1.0 | -1.3 | 0.7 | 0.0 | 0.4 | 0.3 |
Unable to work because of sickness or disability | 0.8 | 1.0 | 2.6 | 1.0 | 1.6 | 1.5 | -0.5 | -0.6 | -0.3 | 0.4 | 0.7 | -1.6 |
Supplements: Calcium | 0.8 | 0.8 | 2.9 | -0.3 | -1.5 | -1.7 | 0.2 | 1.0 | -0.6 | -0.3 | -0.4 | -0.9 |
Bipolar Disorder (2018) | 0.7 | 1.1 | 3.4 | -1.5 | 0.2 | 0.1 | -1.9 | 0.4 | -0.9 | -0.6 | -0.3 | 1.6 |
Intelligence (Savage-Jansen 2018) | 0.7 | 2.3 | 7.9 | -0.3 | -2.8 | -2.4 | 0.3 | -0.3 | -2.4 | -0.3 | -0.3 | -0.7 |
Schizophrenia (2018) | 0.7 | 1.5 | 8.2 | -2.9 | -0.7 | 0.2 | -0.7 | 0.5 | -0.4 | 1.0 | 0.6 | 1.7 |
Worry (Nagel 2018) | 0.7 | 1.5 | 4.5 | -1.6 | 2.1 | 2.1 | -0.6 | 0.1 | 0.8 | -0.7 | -0.3 | 1.0 |
Major Depression (MDD) | 0.7 | 0.8 | 5.6 | -2.4 | 0.8 | 0.3 | -0.7 | -0.0 | -0.7 | 0.3 | 0.2 | 0.2 |
Blood White Count | 0.7 | 5.5 | 20.8 | 1.5 | 4.6 | 4.4 | -0.8 | -0.2 | 1.9 | -1.1 | -0.9 | -0.9 |
Allergy or Eczema | 0.7 | 1.8 | 7.3 | 0.9 | -2.3 | -2.7 | -1.5 | -0.6 | 0.4 | 0.5 | 0.4 | -0.4 |
Neuroticism | 0.7 | 1.8 | 6.8 | -1.2 | 0.2 | 0.3 | -0.3 | -0.2 | 0.7 | -2.6 | -2.3 | 1.2 |
Hearing difficulty/problems: Yes | 0.7 | 1.0 | 3.3 | 1.0 | -0.5 | -0.5 | -1.2 | -1.8 | 1.1 | 0.7 | 0.4 | 1.0 |
Medication: Metformin | 0.7 | 1.0 | 2.3 | -0.1 | -1.4 | -1.5 | 0.3 | -0.7 | -0.3 | 1.1 | 1.3 | -1.3 |
Average weekly fortified wine intake | 0.7 | 0.8 | 2.1 | -0.8 | -1.2 | -1.4 | 1.1 | 0.4 | -1.4 | 0.0 | 0.1 | 0.5 |
Fed-up feelings | 0.7 | 1.3 | 4.7 | -2.2 | -0.4 | 0.0 | -0.2 | -0.1 | -1.6 | -1.2 | -0.8 | -1.5 |
Relative age voice broke | 0.7 | 1.1 | 2.7 | -0.8 | -0.3 | -0.1 | -1.6 | -0.8 | -1.6 | 1.0 | 1.0 | 0.9 |
Serious illness, injury or assault to yourself | 0.7 | 0.8 | 2.1 | -0.1 | -1.4 | -1.1 | -0.3 | -0.3 | -0.7 | 0.7 | 0.9 | -1.3 |
Sitting height | 0.7 | 5.0 | 14.9 | -1.0 | -3.9 | -3.6 | -0.2 | 0.4 | -2.2 | -1.7 | -1.5 | -2.4 |
Falls in the last year | 0.7 | 0.9 | 3.0 | -0.4 | -0.7 | -0.7 | 1.7 | 0.9 | 0.8 | 1.0 | 1.1 | -0.2 |
Noisy workplace | 0.7 | 0.8 | 1.8 | -0.2 | 1.0 | 1.0 | 0.9 | 1.4 | 0.9 | -0.8 | -0.6 | -0.8 |
Asthma | 0.7 | 1.3 | 3.1 | 0.7 | -1.6 | -1.6 | -0.6 | -0.9 | -1.8 | -1.0 | -1.0 | -0.2 |
Medication: Lansoprazole | 0.7 | 0.8 | 3.2 | -1.8 | -0.2 | -0.6 | 0.5 | 1.3 | 1.4 | 0.2 | 0.2 | 0.1 |
Prospective memory result | 0.7 | 0.8 | 3.6 | -0.3 | 0.7 | 0.2 | -0.5 | 0.4 | -0.3 | 1.9 | 1.6 | -0.2 |
Qualifications: O levels/GCSEs or equivalent | 0.7 | 1.1 | 4.3 | 0.4 | -0.2 | -0.1 | -1.5 | -2.1 | 0.1 | 1.1 | 1.3 | 0.5 |
Number of full brothers | 0.7 | 0.9 | 3.1 | 1.1 | -0.5 | -0.3 | -0.2 | -0.8 | 0.5 | 1.8 | 1.6 | -0.3 |
Neck or shoulder pain in last month | 0.7 | 1.0 | 2.6 | 1.6 | -0.5 | -0.2 | -1.1 | -1.1 | -1.6 | 0.4 | 0.4 | -0.8 |
Migraine (self-reported) | 0.7 | 0.9 | 2.9 | 1.3 | 0.8 | 0.6 | -1.7 | -1.3 | -0.3 | -0.2 | -0.4 | 0.5 |
Medication: Ibuprofen | 0.7 | 0.9 | 3.1 | 1.0 | 0.3 | 0.1 | 0.6 | 1.8 | -0.2 | 0.3 | 0.3 | -1.7 |
Medication: Allopurinol | 0.7 | 0.9 | 3.1 | -0.5 | -0.0 | 0.3 | 0.2 | -0.9 | -0.2 | 1.6 | 1.8 | -1.1 |
Reproduciblity of spirometry measurement using ERS/ATS criteria | 0.7 | 0.8 | 3.1 | 0.7 | 0.9 | 0.0 | -1.8 | -1.4 | 0.8 | 0.5 | 0.4 | -0.4 |
Alcohol intake frequency. | 0.7 | 1.7 | 8.1 | 2.2 | -0.3 | -1.0 | -0.5 | -0.0 | -1.0 | -0.1 | 0.2 | -2.8 |
Illness, injury, bereavement, stress in last 2 years | 0.7 | 0.9 | 3.6 | 1.9 | 0.8 | -0.0 | 0.2 | -0.2 | 1.5 | 1.1 | 0.4 | 0.2 |
Illnesses of siblings: Diabetes | 0.7 | 0.9 | 2.6 | -0.9 | 1.5 | 1.6 | 0.5 | 0.2 | 0.8 | -0.7 | -0.7 | 0.7 |
Ever had bowel cancer screening | 0.7 | 0.8 | 2.5 | -0.7 | 1.0 | 1.6 | -0.8 | -1.0 | 0.8 | 0.7 | 0.5 | 0.8 |
Friendships satisfaction | 0.7 | 0.9 | 5.3 | 2.3 | 0.4 | -0.2 | 0.1 | -0.4 | 1.0 | 0.8 | 0.7 | 0.2 |
Irritability | 0.7 | 1.2 | 3.3 | -0.0 | -0.3 | -0.2 | -1.2 | -0.7 | 0.3 | -1.7 | -1.4 | 1.8 |
Medication: Omeprazole (e.g. Zanprol) | 0.7 | 0.9 | 2.8 | -0.1 | 0.4 | 0.2 | 1.2 | 1.7 | -1.2 | -0.3 | 0.2 | -1.5 |
Impedance of whole body | 0.7 | 3.3 | 11.8 | -1.2 | 2.7 | 2.8 | -0.5 | -0.8 | 0.6 | -0.1 | -0.6 | 3.4 |
Alzheimer’s Disease (including proxy) | 0.6 | 0.9 | 2.2 | -1.2 | 0.7 | 1.0 | -0.7 | 0.5 | -0.1 | 1.0 | 1.0 | -1.5 |
Irritable Bowel Disease (IBD) | 0.6 | 1.3 | 3.3 | -0.2 | -1.7 | -1.2 | 1.0 | 1.8 | -1.2 | 0.8 | 0.9 | -0.6 |
Triglycerides | 0.6 | 0.9 | 2.0 | -1.2 | 0.8 | 0.8 | -1.4 | -0.3 | 1.2 | 0.7 | 1.2 | -0.4 |
Chronotype (morning person) | 0.6 | 1.3 | 4.2 | -0.5 | 1.9 | 2.1 | -0.9 | -0.0 | 0.4 | 0.7 | 0.4 | 1.5 |
Hand grip strength (left) | 0.6 | 1.5 | 3.3 | -0.0 | -1.8 | -1.7 | 1.4 | 1.3 | -1.2 | 0.0 | 0.4 | -1.5 |
Number of treatments/medications taken | 0.6 | 1.1 | 3.0 | 1.7 | 0.2 | 0.2 | 0.1 | 0.6 | 0.7 | 1.5 | 1.6 | -1.3 |
Frequency of unenthusiasm / disinterest in last 2 weeks | 0.6 | 0.9 | 5.5 | -0.0 | 0.7 | 0.4 | 0.8 | 2.4 | 0.7 | -0.6 | -0.1 | -0.1 |
Tinnitus: Yes, but not now, but have in the past | 0.6 | 0.6 | 1.9 | 1.2 | 0.1 | 0.1 | 0.8 | 0.1 | 1.4 | -0.0 | 0.5 | -1.1 |
Past tobacco smoking | 0.6 | 1.0 | 2.6 | -1.0 | 1.0 | 0.6 | -0.3 | 1.6 | -0.3 | 1.5 | 1.4 | 0.1 |
Frequency of tenseness / restlessness in last 2 weeks | 0.6 | 0.9 | 2.5 | -1.1 | 1.0 | 0.5 | 1.1 | 1.6 | 0.6 | -0.5 | -0.3 | 0.8 |
Mouth/teeth dental problems | 0.6 | 0.9 | 3.2 | -0.7 | -0.8 | -0.7 | 0.8 | 1.0 | -1.8 | -0.1 | -0.2 | 1.3 |
Exposure to tobacco smoke at home | 0.6 | 0.6 | 1.8 | -1.3 | 0.2 | -0.4 | -0.0 | -1.4 | 1.0 | 0.5 | 0.5 | -0.7 |
Health satisfaction | 0.6 | 0.7 | 2.3 | 1.0 | -0.3 | -0.4 | -0.2 | -1.4 | -1.5 | 0.2 | 0.2 | -1.0 |
Medication for pain relief, constipation, heartburn | 0.6 | 1.0 | 5.5 | -0.5 | -0.9 | -1.0 | 0.6 | 0.1 | -0.6 | 0.5 | -0.1 | 2.3 |
Comparative height size at age 10 | 0.6 | 3.1 | 7.6 | -0.7 | -2.8 | -2.3 | 1.5 | 1.1 | -0.7 | -2.3 | -2.2 | -0.4 |
Suffer from ‘nerves’ | 0.6 | 1.0 | 1.6 | -1.3 | 1.2 | 1.2 | -0.4 | 1.0 | 1.0 | -0.9 | -0.5 | 1.1 |
Family relationship satisfaction | 0.6 | 0.8 | 2.9 | 1.7 | -0.5 | -0.8 | 1.5 | 0.1 | -0.2 | 0.2 | 0.2 | -0.9 |
Medication: Gliclazide | 0.6 | 0.7 | 1.9 | 1.3 | -0.4 | -0.9 | 0.4 | -0.2 | -0.4 | 1.4 | 1.0 | 0.3 |
Number of self-reported non-cancer illnesses | 0.6 | 1.0 | 3.4 | -0.5 | 1.7 | 1.8 | -0.5 | -0.3 | -1.2 | -0.6 | -0.3 | -0.0 |
Ever taken oral contraceptive pill | 0.6 | 0.6 | 2.1 | -0.9 | -1.4 | -1.2 | 0.0 | 0.0 | 0.5 | -0.3 | -0.3 | 1.1 |
Commuting to job workplace: Public transport | 0.6 | 0.7 | 2.7 | -0.2 | -1.7 | -1.3 | 0.3 | 0.5 | -0.2 | -0.3 | -0.3 | 1.1 |
Eye problems/disorders: Glaucoma | 0.6 | 0.8 | 3.8 | -0.3 | 0.2 | 0.9 | -1.2 | -1.9 | 0.2 | -0.5 | -0.4 | -0.1 |
Alzheimer’s Disease (in father) | 0.5 | 0.5 | 2.9 | -0.2 | 0.8 | 0.4 | 0.4 | 0.7 | 0.3 | 0.1 | 0.3 | -1.7 |
HbA1C | 0.5 | 0.6 | 1.1 | -0.7 | -0.5 | -0.4 | 1.0 | 1.0 | 0.9 | -0.8 | -0.6 | 0.5 |
Lung FEV1/FVC ratio | 0.5 | 2.6 | 10.0 | -0.8 | 1.2 | 0.5 | 1.8 | 3.2 | 0.1 | -1.6 | -1.6 | -1.7 |
Ever used hormone-replacement therapy (HRT) | 0.5 | 0.7 | 2.6 | -0.9 | -1.1 | -0.3 | 0.6 | 0.4 | -0.7 | -0.2 | -0.0 | -1.6 |
Maternal smoking around birth | 0.5 | 0.7 | 5.0 | 0.3 | -0.6 | -0.3 | 2.2 | 0.3 | 0.5 | 0.4 | 0.8 | -0.3 |
Stomach or abdominal pain in last month | 0.5 | 0.6 | 1.7 | 0.7 | 0.7 | -0.4 | 1.2 | 0.4 | 1.3 | -0.4 | -0.4 | 0.6 |
Alcohol usually taken with meals | 0.5 | 0.8 | 3.2 | -0.7 | -1.1 | -0.7 | -0.8 | -0.9 | -1.8 | 0.4 | 0.4 | -0.1 |
Financial difficulties in last 2 years | 0.5 | 0.6 | 2.7 | 0.1 | 1.1 | 0.6 | -0.4 | -1.6 | 0.7 | 0.3 | 0.7 | -0.5 |
Fluid intelligence score | 0.5 | 1.1 | 2.7 | 1.1 | -1.6 | -1.6 | 0.4 | -1.4 | -0.0 | -0.6 | -0.6 | 1.0 |
Worrier / anxious feelings | 0.5 | 0.9 | 4.5 | -2.1 | 1.2 | 1.1 | 0.7 | 0.3 | 0.1 | -0.1 | 0.4 | 0.6 |
Medication: Ventolin 100micrograms inhaler | 0.5 | 0.6 | 2.2 | -1.1 | -0.4 | -0.6 | 0.7 | -0.4 | -0.1 | -0.8 | -0.6 | -1.5 |
Angina (self-reported) | 0.5 | 0.6 | 2.1 | 0.3 | 0.5 | 0.7 | 1.0 | 0.7 | 0.2 | -1.4 | -1.1 | -0.0 |
Mouth/teeth dental problems: Mouth ulcers | 0.5 | 0.8 | 2.5 | 0.2 | 1.1 | 1.4 | 0.3 | 0.8 | 1.6 | 0.2 | 0.3 | -0.4 |
Back pain experienced in last month | 0.5 | 0.7 | 3.2 | 0.1 | -1.8 | -1.3 | -0.3 | 0.0 | -0.8 | 0.5 | 0.7 | 0.2 |
Mineral and other dietary supplements | 0.5 | 0.7 | 2.3 | -0.2 | 0.6 | -0.0 | -0.3 | 0.7 | 0.5 | -1.5 | -1.4 | 0.9 |
Asthma (self-reported) | 0.5 | 1.1 | 2.4 | 0.5 | -1.5 | -1.4 | -0.8 | -1.0 | -1.5 | -0.7 | -0.7 | 0.1 |
Miserableness | 0.5 | 0.9 | 3.2 | -1.8 | 0.3 | 0.4 | -1.2 | -1.0 | -1.2 | 0.7 | 0.9 | -0.1 |
Guilty feelings | 0.5 | 0.8 | 2.3 | -0.6 | -0.8 | -0.3 | 0.4 | 1.1 | -0.6 | -1.5 | -1.3 | 0.5 |
Depression (Nagel 2018) | 0.4 | 0.6 | 1.2 | -1.1 | 0.7 | 0.8 | 0.8 | 1.1 | 1.0 | -0.7 | -0.2 | 0.1 |
Neuroticism (Nagel 2018) | 0.4 | 0.9 | 3.2 | -1.8 | 1.1 | 1.1 | 0.2 | 0.4 | 0.7 | -0.9 | -0.5 | 0.7 |
Alzheimer’s Disease (in mother) | 0.4 | 0.4 | 2.2 | -1.5 | 0.2 | 0.7 | -0.2 | 0.4 | 0.4 | 0.7 | 0.3 | -0.0 |
Ulcerative Colitis (UC) | 0.4 | 0.8 | 1.7 | 0.4 | -0.4 | -0.0 | 1.1 | 1.3 | -0.4 | 1.3 | 1.2 | -0.8 |
Verbal and Numeric Reasoning (VNR) | 0.4 | 1.0 | 3.4 | 0.6 | -1.8 | -1.4 | 0.7 | -0.9 | -1.1 | -0.5 | -0.4 | -0.5 |
Prostate Cancer | 0.4 | 0.6 | 2.3 | 0.1 | 0.4 | 0.1 | 0.4 | 0.9 | 1.5 | -1.0 | -0.9 | -0.1 |
Mean Putamen Volume | 0.4 | 0.4 | 1.0 | 0.5 | -0.6 | -0.9 | -0.2 | -0.4 | -1.0 | -0.5 | -0.3 | -0.9 |
Rheumatoid Arthritis | 0.4 | 0.5 | 2.2 | 1.5 | -0.3 | -0.3 | 0.8 | 1.1 | 0.4 | 0.4 | 0.5 | 0.3 |
BMI | 0.4 | 2.3 | 17.8 | 0.8 | -0.2 | -0.4 | 1.1 | 0.9 | -0.5 | -0.0 | 0.3 | -4.2 |
Hair Pigment | 0.4 | 10.0 | 30.0 | 0.1 | 3.3 | 2.5 | 0.2 | 2.3 | 3.1 | -5.2 | -5.5 | -0.7 |
Pack years adult smoking proportion | 0.4 | 0.5 | 3.6 | 0.8 | 0.4 | 0.1 | 1.9 | 0.2 | 0.3 | -0.1 | 0.6 | -0.1 |
Townsend deprivation index at recruitment | 0.4 | 0.6 | 2.8 | 0.5 | 0.2 | 0.6 | 1.1 | -0.2 | 0.1 | -0.6 | -0.6 | -1.7 |
Taking other prescription medications | 0.4 | 0.6 | 1.4 | 1.1 | 0.7 | 0.8 | 0.7 | 0.9 | -0.6 | 0.0 | 0.1 | -1.2 |
Supplements: Glucosamine | 0.4 | 0.6 | 1.1 | -0.2 | 0.4 | 0.9 | 0.7 | -0.9 | 0.2 | 1.0 | 1.0 | -1.0 |
Diverticular disease/diverticulitis (self-reported) | 0.4 | 0.4 | 1.5 | -1.1 | 0.0 | 0.2 | 0.2 | -0.1 | 1.2 | -0.5 | -0.9 | -0.5 |
Number of incorrect matches in round | 0.4 | 0.7 | 1.5 | -0.7 | 0.9 | 1.0 | -1.2 | 0.6 | 0.5 | 1.0 | 0.5 | 0.4 |
Qualifications: None of the above | 0.4 | 0.9 | 4.3 | -0.1 | 1.4 | 0.9 | 0.8 | 2.1 | -0.0 | -0.1 | -0.4 | 0.2 |
Qualifications: A levels/AS levels or equivalent | 0.4 | 0.9 | 2.5 | 0.1 | -1.5 | -1.1 | -0.4 | -1.6 | -1.2 | -0.6 | -0.5 | -0.2 |
Serious illness, injury or assault of a close relative in last 2 years | 0.4 | 0.5 | 1.8 | -0.6 | -1.3 | -1.1 | -0.6 | 0.3 | -0.2 | 0.3 | 0.4 | 0.6 |
Medication: Ibuprofen (e.g. Nurofen) | 0.4 | 0.5 | 1.5 | 0.2 | 0.6 | 0.5 | 0.3 | 0.7 | -0.2 | -0.8 | -1.0 | -1.2 |
Impedance of arm (left) | 0.4 | 1.8 | 7.7 | -0.0 | 1.8 | 2.0 | -0.8 | -0.9 | -0.1 | 0.5 | 0.0 | 2.8 |
Arm fat mass (right) | 0.4 | 1.7 | 9.4 | 0.7 | -1.0 | -1.2 | 0.7 | 0.4 | -1.4 | -0.6 | -0.2 | -3.1 |
Tense / ‘highly strung’ | 0.4 | 0.6 | 1.7 | -1.0 | 1.3 | 1.3 | -0.3 | -0.7 | 0.7 | -0.5 | -0.4 | 0.1 |
Medication: Paracetamol | 0.4 | 0.6 | 2.1 | 0.9 | 1.1 | 0.8 | -0.3 | -0.5 | 0.4 | -0.0 | 0.5 | -1.5 |
Comparative body size at age 10 | 0.4 | 1.1 | 5.1 | -0.9 | 0.5 | 0.5 | 1.0 | 0.1 | 1.2 | 0.8 | 0.6 | -2.2 |
Age at first live birth | 0.4 | 0.8 | 2.6 | 0.9 | 0.5 | 0.4 | -0.7 | 0.6 | -0.5 | -1.4 | -1.6 | 0.6 |
Eye problems/disorders: None of the above | 0.4 | 0.4 | 2.5 | 0.1 | 0.3 | -0.2 | 0.3 | 0.8 | -1.6 | -0.3 | -0.4 | -0.2 |
Emphysema/chronic bronchitis | 0.4 | 0.4 | 1.2 | -0.5 | -0.6 | -1.0 | -1.1 | -0.6 | 0.2 | -0.3 | -0.6 | -0.2 |
Medication: Seretide 50 evohaler | 0.4 | 0.5 | 1.1 | 1.0 | 1.1 | 0.9 | 0.0 | -0.4 | 0.7 | -0.4 | -0.4 | 0.6 |
Whole body fat mass | 0.4 | 1.5 | 7.2 | 0.5 | -0.8 | -1.0 | 0.1 | 0.1 | -2.1 | -0.5 | -0.1 | -2.7 |
Age at last live birth | 0.4 | 0.5 | 1.4 | -0.4 | 0.9 | 1.2 | -0.0 | 0.6 | 0.2 | -0.6 | -0.8 | 1.0 |
Leg pain on walking | 0.4 | 0.5 | 1.4 | -0.4 | -0.0 | 0.1 | -0.6 | 0.1 | -0.8 | -1.2 | -1.2 | 0.5 |
Smoking status: Current | 0.4 | 0.6 | 1.8 | 1.3 | 0.2 | -0.6 | -0.0 | -0.5 | 1.4 | -0.8 | -0.5 | -0.5 |
Arm fat mass (left) | 0.4 | 1.7 | 9.5 | 0.7 | -0.9 | -1.2 | 0.4 | 0.5 | -1.5 | -0.5 | -0.2 | -3.1 |
Hearing aid user | 0.4 | 0.5 | 1.4 | -0.0 | -0.0 | -0.4 | -1.0 | 0.2 | -0.8 | 1.2 | 0.9 | 0.6 |
Financial situation satisfaction | 0.4 | 0.5 | 1.5 | -0.1 | -0.7 | -0.7 | 0.1 | 0.3 | -0.5 | 1.1 | 1.2 | -0.1 |
Supplements: Fish oil (including cod liver oil) | 0.4 | 0.6 | 1.2 | -1.1 | 0.2 | 0.7 | -1.1 | -0.1 | -0.5 | 1.0 | 0.6 | 0.7 |
Average weekly beer plus cider intake | 0.4 | 0.6 | 2.7 | -0.7 | 0.9 | 0.3 | 1.1 | -0.1 | 1.6 | 0.2 | 0.6 | 0.2 |
Risk taking | 0.4 | 0.5 | 2.2 | 0.2 | 0.6 | 0.2 | -1.0 | -1.5 | 0.8 | 0.6 | 0.6 | 0.1 |
Ever depressed for a whole week | 0.4 | 0.5 | 1.8 | -0.1 | -0.7 | -0.8 | 1.3 | 1.1 | 0.1 | -0.5 | -0.0 | -0.7 |
Pack years of smoking | 0.4 | 0.6 | 3.5 | 1.1 | 0.4 | 0.2 | 1.9 | 0.0 | 0.7 | -0.2 | 0.4 | -0.2 |
Depressed Affect (Nagel 2018) | 0.3 | 0.5 | 3.6 | -1.9 | 0.5 | 0.4 | 0.2 | -0.7 | 0.1 | -0.2 | 0.2 | -0.4 |
Breast Cancer | 0.3 | 0.8 | 1.7 | 0.4 | -0.3 | -0.4 | 1.0 | -0.2 | -1.3 | 1.2 | 1.2 | 1.1 |
Age at First Birth | 0.3 | 0.4 | 2.0 | -0.1 | -0.2 | -0.4 | 0.7 | -0.3 | 0.5 | 0.2 | -0.3 | 1.4 |
Primary Biliary Cirrhosis | 0.3 | 0.4 | 0.9 | 0.9 | -0.2 | -0.6 | -0.1 | -0.2 | -0.9 | 1.0 | 0.6 | -0.1 |
Blood Eosinophil Count | 0.3 | 2.0 | 8.4 | -0.8 | 1.9 | 2.9 | 1.2 | -0.9 | 0.6 | -1.3 | -0.9 | 0.3 |
Smoking Status | 0.3 | 0.6 | 2.1 | 1.3 | -0.1 | -0.1 | -0.5 | -1.5 | 0.5 | -0.8 | -0.7 | 0.2 |
Eye problems/disorders: Diabetes related eye disease | 0.3 | 0.3 | 1.2 | -0.5 | 0.7 | 0.2 | -0.2 | -0.0 | 0.4 | -0.6 | -0.5 | -1.1 |
Angina | 0.3 | 0.4 | 1.5 | 0.2 | 0.4 | 0.6 | 0.7 | 0.5 | 0.4 | -1.2 | -0.9 | 0.2 |
Medication for hormone replacement therapy | 0.3 | 0.3 | 1.3 | 0.4 | -0.2 | 0.0 | -0.1 | 0.2 | 0.1 | -1.0 | -1.1 | -0.0 |
Medication: Co-codamol | 0.3 | 0.4 | 1.7 | 0.1 | -0.2 | -1.3 | 0.2 | -0.6 | -0.1 | 0.7 | 0.8 | 0.5 |
Qualifications: CSEs or equivalent | 0.3 | 0.4 | 1.3 | 0.8 | 0.0 | -0.1 | 0.7 | 0.5 | 1.2 | -0.5 | -0.4 | 0.1 |
Chronic bronchitis/emphysema (father) | 0.3 | 0.4 | 1.5 | 1.2 | 0.9 | 0.6 | 0.3 | -0.9 | 0.2 | 0.0 | -0.0 | 0.4 |
Body mass index (BMI) | 0.3 | 1.2 | 8.3 | 0.9 | -0.0 | -0.3 | 0.3 | 0.5 | -1.1 | -0.2 | 0.3 | -2.9 |
Trunk fat mass | 0.3 | 1.4 | 5.0 | 0.4 | -0.8 | -1.0 | 0.0 | 0.0 | -2.2 | -0.9 | -0.6 | -2.2 |
Waist circumference | 0.3 | 1.1 | 2.9 | 0.5 | 0.6 | 0.2 | -0.1 | -0.8 | -1.6 | -1.4 | -1.2 | -1.7 |
Nervous feelings | 0.3 | 0.5 | 1.5 | -1.1 | -0.3 | 0.0 | -0.7 | -0.2 | -0.1 | -1.2 | -1.1 | -0.3 |
Impedance of arm (right) | 0.3 | 1.3 | 5.8 | 0.3 | 1.3 | 1.4 | -0.1 | -1.3 | 0.0 | 0.4 | -0.0 | 2.4 |
Frequency of tiredness / lethargy in last 2 weeks | 0.3 | 0.4 | 1.3 | -1.0 | 1.1 | 0.7 | 0.9 | 0.3 | 0.2 | -0.3 | -0.1 | 0.0 |
Seen doctor (GP) for nerves, anxiety, tension or depression | 0.3 | 0.4 | 1.6 | -0.5 | -0.4 | -0.5 | -1.0 | -1.3 | 0.7 | -0.1 | -0.0 | 0.3 |
Headache pain in last month | 0.3 | 0.5 | 3.0 | -0.2 | -0.1 | -0.9 | -1.7 | -0.5 | -0.6 | 0.3 | -0.1 | -0.4 |
Chronic bronchitis/emphysema (mother) | 0.3 | 0.3 | 1.6 | 0.5 | 0.4 | -0.2 | 0.6 | -1.3 | -0.4 | 0.3 | 0.1 | 0.4 |
Leg fat mass (right) | 0.3 | 1.2 | 6.7 | 0.9 | -0.6 | -0.8 | 0.0 | -0.2 | -1.4 | -0.4 | 0.0 | -2.6 |
Pulse rate, automated reading | 0.3 | 1.0 | 4.9 | 0.2 | 0.2 | -0.8 | -0.9 | 1.1 | -2.2 | 0.0 | -0.4 | 0.9 |
Handedness (chirality/laterality): Left-handed | 0.3 | 0.4 | 1.4 | -0.5 | -0.4 | -0.8 | -0.4 | -0.5 | 0.6 | -0.7 | -0.4 | 1.2 |
Medication: Laxatives (e.g. Dulcolax, Senokot) | 0.3 | 0.3 | 1.6 | -0.2 | -0.2 | 0.0 | 0.3 | 1.1 | 0.0 | -0.3 | -0.1 | -1.2 |
Medication: Blood pressure | 0.3 | 0.6 | 2.5 | -0.8 | 0.7 | 1.1 | -0.0 | -0.8 | 0.2 | 0.2 | 0.4 | 1.6 |
Pain type(s) experienced in last month: Hip pain | 0.3 | 0.4 | 1.7 | -0.2 | 1.3 | 0.9 | -0.0 | -0.4 | 0.4 | 0.4 | 0.4 | -0.2 |
Pain experienced in last month | 0.3 | 0.5 | 1.4 | -0.4 | 0.3 | 1.2 | 1.1 | -0.5 | 0.3 | -0.8 | -0.5 | -0.5 |
Leg fat mass (left) | 0.3 | 1.2 | 7.0 | 0.6 | -0.6 | -0.8 | 0.1 | -0.0 | -1.4 | -0.4 | 0.0 | -2.6 |
LDL Cholesterol | 0.2 | 0.4 | 0.7 | -0.5 | 0.7 | 0.8 | -0.0 | -0.7 | 0.6 | 0.3 | 0.5 | -0.8 |
Neuroticism (2016) | 0.2 | 0.3 | 1.2 | -0.2 | 0.4 | 0.1 | -0.5 | -1.1 | 0.7 | -0.3 | -0.3 | -0.3 |
Blood Red Count | 0.2 | 1.6 | 3.4 | -0.1 | 0.7 | 0.2 | 1.4 | 1.3 | -1.1 | -1.6 | -1.7 | -1.9 |
Type 2 Diabetes (T2D) (2018) | 0.2 | 0.3 | 1.0 | -0.7 | -0.1 | -1.0 | 0.6 | -0.1 | 0.3 | 0.6 | 0.7 | 0.0 |
Relative age of first facial hair | 0.2 | 0.5 | 1.2 | -1.0 | -0.9 | -0.7 | -0.2 | -0.3 | -1.1 | -0.7 | -0.5 | 0.0 |
Vitamin and mineral supplements | 0.2 | 0.3 | 1.0 | 0.4 | -0.3 | -0.1 | -0.5 | -1.0 | 0.4 | -0.7 | -0.4 | -0.1 |
Trunk fat percentage | 0.2 | 0.7 | 3.4 | 0.3 | 0.4 | 0.2 | -0.1 | -0.1 | -1.8 | -0.5 | -0.3 | -1.4 |
Hand grip strength (right) | 0.2 | 0.5 | 1.2 | -0.3 | -1.1 | -0.9 | 0.3 | 1.0 | -0.9 | -0.1 | 0.3 | 0.1 |
Current tobacco smoking | 0.2 | 0.4 | 1.0 | 1.0 | 0.6 | -0.1 | -0.5 | -0.5 | 0.9 | -0.3 | -0.1 | -0.7 |
Age when periods started (menarche) | 0.2 | 0.5 | 1.7 | -0.3 | -1.0 | -1.3 | 0.1 | 0.3 | -0.5 | -0.6 | -0.9 | 0.4 |
Diabetes (self-reported) | 0.2 | 0.3 | 0.9 | 0.7 | -0.3 | -1.0 | -0.3 | -0.9 | 0.8 | 0.2 | 0.2 | -0.4 |
Medication: Ramipril | 0.2 | 0.3 | 0.9 | -0.3 | 0.3 | 0.2 | -0.9 | -0.7 | 0.5 | 0.7 | 0.3 | -0.4 |
Arm fat percentage (right) | 0.2 | 0.9 | 4.8 | 1.0 | 0.7 | 0.3 | 0.8 | 0.1 | -1.0 | 0.3 | 0.5 | -2.2 |
Father’s age at death | 0.2 | 0.3 | 0.7 | -0.7 | -0.7 | 0.0 | -0.3 | 0.7 | 0.8 | 0.4 | -0.0 | 0.1 |
Happiness | 0.2 | 0.2 | 0.7 | 0.5 | -0.1 | 0.0 | -0.1 | -0.5 | 0.8 | -0.4 | -0.3 | -0.7 |
Breastfed as a baby | 0.2 | 0.2 | 0.6 | -0.6 | 0.2 | 0.8 | -0.6 | -0.6 | 0.0 | 0.4 | -0.2 | 0.5 |
Hair/balding pattern: Pattern 4 | 0.2 | 0.6 | 2.9 | 0.8 | 0.9 | 0.8 | 1.7 | 0.3 | -0.3 | -0.2 | -0.1 | -0.3 |
Body fat percentage | 0.2 | 0.6 | 2.1 | 0.4 | 0.9 | 0.8 | -0.0 | -0.1 | -1.4 | -0.2 | 0.0 | -1.4 |
Leg fat percentage (right) | 0.2 | 0.9 | 2.7 | 0.5 | 1.7 | 1.5 | -0.1 | -0.5 | -0.4 | 0.2 | 0.4 | -1.4 |
Wheeze or whistling in the chest in last year | 0.2 | 0.4 | 2.5 | 1.6 | 0.1 | 0.2 | -0.3 | -0.1 | -0.1 | 0.5 | 0.6 | -0.1 |
Qualifications: College or University degree | 0.2 | 0.5 | 1.8 | 0.1 | -0.4 | -0.2 | 1.4 | 0.2 | -0.7 | 0.7 | 0.7 | 1.0 |
Overall health rating | 0.2 | 0.5 | 1.2 | 0.2 | 0.7 | 0.4 | -0.5 | 0.7 | -1.1 | 0.8 | 1.0 | -0.3 |
Smoking status: Previous | 0.2 | 0.3 | 1.0 | -0.3 | -0.4 | 0.4 | 0.5 | -1.0 | -0.1 | -0.7 | -0.7 | -0.0 |
Arm fat percentage (left) | 0.2 | 0.9 | 4.2 | 0.8 | 0.8 | 0.5 | 0.2 | 0.0 | -1.3 | 0.3 | 0.5 | -2.0 |
Mood swings | 0.2 | 0.4 | 1.7 | -1.3 | 0.1 | -0.2 | 0.2 | -0.7 | -0.3 | -0.9 | -0.4 | 0.0 |
Diabetes diagnosed by doctor | 0.2 | 0.3 | 1.4 | 0.2 | -0.5 | -1.2 | 0.1 | -0.7 | -0.1 | 0.1 | 0.2 | -0.0 |
Medication for cholesterol | 0.2 | 0.3 | 0.8 | 0.6 | 0.1 | -0.4 | -0.5 | -0.2 | 0.6 | 0.7 | 0.6 | -0.9 |
Medication: Atorvastatin | 0.2 | 0.2 | 0.5 | -0.7 | 0.1 | 0.6 | 0.1 | -0.2 | -0.1 | 0.7 | 0.7 | 0.5 |
Leg fat percentage (left) | 0.2 | 0.8 | 2.4 | -0.0 | 1.6 | 1.5 | -0.1 | -0.2 | -0.4 | -0.1 | 0.1 | -1.5 |
Tanning | 0.1 | 1.8 | 7.7 | -0.2 | -2.8 | -2.8 | -0.4 | -0.5 | -0.6 | 0.0 | -0.0 | -0.2 |
Cholesterol lowering medication | 0.1 | 0.2 | 0.6 | 0.1 | -0.4 | 0.0 | 0.8 | -0.2 | -0.5 | -0.1 | 0.2 | -0.6 |