Hub : Genes

ARHGAP24

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.0690 0.0270 3.5e-03 0.002 0.014 0.016 0.016 0.015 1.5e-01 6.4e-03 4.2e-03 4.6e-03 5.8e-03
2 GTEx Artery Aorta 0.2410 0.0760 2.4e-03 0.132 NA 0.145 NA 0.126 1.0e-07 NA 2.2e-08 NA 2.1e-07
3 GTEx Artery Tibial 0.2592 0.0548 3.1e-06 0.186 NA 0.209 NA 0.181 1.5e-14 NA 2.7e-16 NA 3.7e-14
4 GTEx Breast Mammary Tissue (Male) 0.2394 0.1530 6.8e-02 -0.012 NA 0.006 NA -0.013 7.4e-01 NA 2.3e-01 NA 9.4e-01
5 GTEx Heart Left Ventricle 0.0902 0.0391 3.8e-03 0.060 NA 0.017 NA 0.033 3.9e-04 NA 4.3e-02 NA 7.2e-03
6 GTEx Nerve Tibial 0.2403 0.0647 5.2e-04 0.039 NA 0.075 NA 0.030 9.5e-04 NA 5.6e-06 NA 3.3e-03
7 NTR Blood 0.0554 0.0126 1.1e-12 0.050 0.045 0.054 0.053 0.055 1.1e-15 2.7e-14 6.1e-17 1.4e-16 2.7e-17
8 YFS Blood 0.1655 0.0231 0.0e+00 0.192 0.178 0.186 0.192 0.195 1.3e-60 7.6e-56 1.1e-58 1.2e-60 1.1e-61
9 TCGA Brain Lower Grade Glioma 0.0500 0.0229 7.3e-03 -0.002 0.006 -0.001 NA -0.002 7.9e-01 6.1e-02 4.5e-01 NA 8.2e-01

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bipolar Disorder (2018) 0.7 1.1 3.4 -1.5 0.2 0.1 -1.9 0.4 -0.9 -0.6 -0.3 1.6
Bipolar Disorder or Schizophrenia 0.9 2.1 8.6 -2.9 -0.4 0.2 -1.7 0.6 -0.9 0.4 0.3 2.4
Depressed Affect (Nagel 2018) 0.3 0.5 3.6 -1.9 0.5 0.4 0.2 -0.7 0.1 -0.2 0.2 -0.4
Depression (Nagel 2018) 0.4 0.6 1.2 -1.1 0.7 0.8 0.8 1.1 1.0 -0.7 -0.2 0.1
Intelligence (Savage-Jansen 2018) 0.7 2.3 7.9 -0.3 -2.8 -2.4 0.3 -0.3 -2.4 -0.3 -0.3 -0.7
Neuroticism (Nagel 2018) 0.4 0.9 3.2 -1.8 1.1 1.1 0.2 0.4 0.7 -0.9 -0.5 0.7
Schizophrenia (2018) 0.7 1.5 8.2 -2.9 -0.7 0.2 -0.7 0.5 -0.4 1.0 0.6 1.7
Schizophrenia vs Biploar Disorder 1.0 1.3 4.5 0.3 -0.2 0.0 -0.5 -0.8 1.1 2.1 1.7 -1.5
Worry (Nagel 2018) 0.7 1.5 4.5 -1.6 2.1 2.1 -0.6 0.1 0.8 -0.7 -0.3 1.0
Alzheimer’s Disease (in mother) 0.4 0.4 2.2 -1.5 0.2 0.7 -0.2 0.4 0.4 0.7 0.3 -0.0
Alzheimer’s Disease (in father) 0.5 0.5 2.9 -0.2 0.8 0.4 0.4 0.7 0.3 0.1 0.3 -1.7
Alzheimer’s Disease (including proxy) 0.6 0.9 2.2 -1.2 0.7 1.0 -0.7 0.5 -0.1 1.0 1.0 -1.5
Crohns Disease (2017) 0.9 2.0 6.0 -0.8 -2.4 -1.9 0.5 1.9 -1.9 0.2 0.3 -0.5
Irritable Bowel Disease (IBD) 0.6 1.3 3.3 -0.2 -1.7 -1.2 1.0 1.8 -1.2 0.8 0.9 -0.6
Ulcerative Colitis (UC) 0.4 0.8 1.7 0.4 -0.4 -0.0 1.1 1.3 -0.4 1.3 1.2 -0.8
Major Depression (MDD) 0.7 0.8 5.6 -2.4 0.8 0.3 -0.7 -0.0 -0.7 0.3 0.2 0.2
Reaction Time 1.0 1.8 7.8 -0.1 -0.0 -0.1 -1.6 -2.8 -1.3 -0.5 -0.5 1.9
Verbal and Numeric Reasoning (VNR) 0.4 1.0 3.4 0.6 -1.8 -1.4 0.7 -0.9 -1.1 -0.5 -0.4 -0.5
Breast Cancer 0.3 0.8 1.7 0.4 -0.3 -0.4 1.0 -0.2 -1.3 1.2 1.2 1.1
Ovarian Cancer 0.8 1.1 2.9 1.3 1.1 0.6 -0.4 -0.5 -0.2 1.7 1.3 -1.4
Prostate Cancer 0.4 0.6 2.3 0.1 0.4 0.1 0.4 0.9 1.5 -1.0 -0.9 -0.1
Age at First Birth 0.3 0.4 2.0 -0.1 -0.2 -0.4 0.7 -0.3 0.5 0.2 -0.3 1.4
Bipolar Disorder (2011) 3.9 3.8 11.9 -3.4 0.4 1.1 -2.5 0.4 -1.3 2.5 2.2 1.3
Body Mass Index (BMI) (2010) 1.0 1.4 3.5 1.0 1.2 0.9 0.5 0.3 0.9 -1.6 -1.6 1.9
Coronary Artery Disease (CAD) 1.4 1.7 4.2 -2.1 -0.1 -0.1 -1.3 0.8 -0.4 -1.7 -1.8 1.5
Crohns Disease (2012) 1.2 1.9 4.1 0.0 -2.0 -2.0 1.5 1.8 -1.5 0.6 0.8 -0.4
Mean Putamen Volume 0.4 0.4 1.0 0.5 -0.6 -0.9 -0.2 -0.4 -1.0 -0.5 -0.3 -0.9
Fasting Glucose 1.0 1.2 3.3 0.7 -1.3 -1.8 1.4 -1.4 -1.1 -0.1 0.1 -0.8
HbA1C 0.5 0.6 1.1 -0.7 -0.5 -0.4 1.0 1.0 0.9 -0.8 -0.6 0.5
HDL Cholesterol 1.2 2.1 5.0 2.2 -1.3 -2.1 1.5 1.8 -1.2 0.1 -0.3 0.2
LDL Cholesterol 0.2 0.4 0.7 -0.5 0.7 0.8 -0.0 -0.7 0.6 0.3 0.5 -0.8
Lupus 1.0 1.6 5.2 -1.4 0.6 0.9 -1.2 0.2 -0.8 -2.3 -2.0 -0.0
Neuroticism (2016) 0.2 0.3 1.2 -0.2 0.4 0.1 -0.5 -1.1 0.7 -0.3 -0.3 -0.3
Primary Biliary Cirrhosis 0.3 0.4 0.9 0.9 -0.2 -0.6 -0.1 -0.2 -0.9 1.0 0.6 -0.1
Rheumatoid Arthritis 0.4 0.5 2.2 1.5 -0.3 -0.3 0.8 1.1 0.4 0.4 0.5 0.3
Schizophrenia (2014) 0.9 1.9 8.3 -2.9 -0.7 -0.1 -1.9 -0.2 -0.3 1.1 0.8 1.7
Triglycerides 0.6 0.9 2.0 -1.2 0.8 0.8 -1.4 -0.3 1.2 0.7 1.2 -0.4
Type 2 Diabetes (T2D) (2012) 1.5 1.7 4.8 -1.9 0.8 1.0 -0.7 -0.6 -0.5 1.9 2.2 -0.5
Ulcerative Colitis 0.9 1.3 3.2 0.0 0.8 0.7 0.9 1.3 1.5 1.8 1.5 0.3
Blood Eosinophil Count 0.3 2.0 8.4 -0.8 1.9 2.9 1.2 -0.9 0.6 -1.3 -0.9 0.3
Blood Platelet Count 1.0 12.1 36.6 3.8 6.0 5.7 -1.3 -4.0 2.2 -0.6 -0.9 1.4
Blood Red Count 0.2 1.6 3.4 -0.1 0.7 0.2 1.4 1.3 -1.1 -1.6 -1.7 -1.9
Blood White Count 0.7 5.5 20.8 1.5 4.6 4.4 -0.8 -0.2 1.9 -1.1 -0.9 -0.9
Heel T-Score 6.0 47.6 179.6 -1.8 13.4 13.1 -1.8 1.0 6.6 -0.8 -0.8 4.9
BMI 0.4 2.3 17.8 0.8 -0.2 -0.4 1.1 0.9 -0.5 -0.0 0.3 -4.2
Height 1.3 24.9 97.0 0.6 -9.8 -9.1 0.7 0.0 -2.9 -3.8 -3.3 -3.3
Waist Hip Ratio (WHR) 1.1 4.8 12.4 0.1 3.1 2.7 -1.2 -2.9 1.5 -0.7 -0.9 3.5
Systolic Blood Pressure 5.6 28.1 112.4 -3.0 10.5 10.6 -0.4 1.7 2.8 0.4 0.1 3.2
Smoking Status 0.3 0.6 2.1 1.3 -0.1 -0.1 -0.5 -1.5 0.5 -0.8 -0.7 0.2
Allergy or Eczema 0.7 1.8 7.3 0.9 -2.3 -2.7 -1.5 -0.6 0.4 0.5 0.4 -0.4
Cardiovascular Disease 1.8 6.0 24.7 -1.0 4.8 5.0 0.1 0.4 1.8 0.5 0.4 1.4
Hypothyroidism (self reported) 0.8 1.9 6.2 0.3 -2.5 -2.4 0.1 0.7 -1.5 -1.0 -0.8 -1.1
Respiratory disease 0.9 2.1 6.9 0.5 -2.4 -2.6 -0.5 -0.9 -0.7 -1.3 -1.3 0.9
Type 2 Diabetes (T2D) (2018) 0.2 0.3 1.0 -0.7 -0.1 -1.0 0.6 -0.1 0.3 0.6 0.7 0.0
Lung FEV1/FVC ratio 0.5 2.6 10.0 -0.8 1.2 0.5 1.8 3.2 0.1 -1.6 -1.6 -1.7
Lung FVC 1.1 5.5 18.7 -0.2 2.7 2.0 3.2 3.0 4.3 -0.6 -0.2 0.4
Neuroticism 0.7 1.8 6.8 -1.2 0.2 0.3 -0.3 -0.2 0.7 -2.6 -2.3 1.2
Chronotype (morning person) 0.6 1.3 4.2 -0.5 1.9 2.1 -0.9 -0.0 0.4 0.7 0.4 1.5
Hair Pigment 0.4 10.0 30.0 0.1 3.3 2.5 0.2 2.3 3.1 -5.2 -5.5 -0.7
Tanning 0.1 1.8 7.7 -0.2 -2.8 -2.8 -0.4 -0.5 -0.6 0.0 -0.0 -0.2
Hand grip strength (left) 0.6 1.5 3.3 -0.0 -1.8 -1.7 1.4 1.3 -1.2 0.0 0.4 -1.5
Number of treatments/medications taken 0.6 1.1 3.0 1.7 0.2 0.2 0.1 0.6 0.7 1.5 1.6 -1.3
Average weekly spirits intake 0.8 1.0 3.9 0.1 0.4 0.3 -2.0 -1.9 -0.4 -0.5 -0.3 -1.0
Sensitivity / hurt feelings 0.9 1.5 7.5 -2.7 -0.3 -0.3 1.0 0.4 -1.2 -1.4 -1.0 0.5
Frequency of depressed mood in last 2 weeks 1.3 1.8 3.2 -1.6 1.0 1.2 1.8 1.3 -0.1 -1.5 -1.3 1.4
Hearing difficulty/problems: Yes 0.7 1.0 3.3 1.0 -0.5 -0.5 -1.2 -1.8 1.1 0.7 0.4 1.0
Relative age of first facial hair 0.2 0.5 1.2 -1.0 -0.9 -0.7 -0.2 -0.3 -1.1 -0.7 -0.5 0.0
Other serious medical condition/disability diagnosed by doctor 1.0 1.3 2.7 0.9 0.5 0.3 -0.6 -1.3 -1.5 1.6 1.5 -1.1
Ever used hormone-replacement therapy (HRT) 0.5 0.7 2.6 -0.9 -1.1 -0.3 0.6 0.4 -0.7 -0.2 -0.0 -1.6
Ever had hysterectomy (womb removed) 2.4 2.7 11.0 -0.3 -1.6 -1.8 -2.4 -3.3 -0.7 0.4 0.1 -1.1
Systolic blood pressure, automated reading 6.1 17.7 76.7 -2.3 8.4 8.8 -1.0 0.1 2.0 0.7 0.5 1.2
Eye problems/disorders: Diabetes related eye disease 0.3 0.3 1.2 -0.5 0.7 0.2 -0.2 -0.0 0.4 -0.6 -0.5 -1.1
Angina 0.3 0.4 1.5 0.2 0.4 0.6 0.7 0.5 0.4 -1.2 -0.9 0.2
Medication for hormone replacement therapy 0.3 0.3 1.3 0.4 -0.2 0.0 -0.1 0.2 0.1 -1.0 -1.1 -0.0
Vitamin and mineral supplements 0.2 0.3 1.0 0.4 -0.3 -0.1 -0.5 -1.0 0.4 -0.7 -0.4 -0.1
Supplements: Zinc 0.8 0.9 4.6 -0.6 -0.8 -0.5 -0.6 -0.3 2.1 0.8 0.7 -0.9
Medication: Co-codamol 0.3 0.4 1.7 0.1 -0.2 -1.3 0.2 -0.6 -0.1 0.7 0.8 0.5
Medication: Metformin 0.7 1.0 2.3 -0.1 -1.4 -1.5 0.3 -0.7 -0.3 1.1 1.3 -1.3
Diabetes (father) 2.0 2.5 6.6 2.6 1.0 0.3 -0.3 -1.6 0.1 2.3 2.6 -0.9
Diabetes (mother) 1.4 1.8 3.6 -1.5 -1.4 -0.9 0.8 1.7 -1.1 -1.3 -0.9 -1.9
Severe depression (siblings) 0.8 0.8 3.4 -0.9 1.8 1.5 -0.4 -0.9 0.2 0.2 0.1 -0.2
Pack years adult smoking proportion 0.4 0.5 3.6 0.8 0.4 0.1 1.9 0.2 0.3 -0.1 0.6 -0.1
Impedance of leg (right) 0.9 4.1 11.5 -1.8 3.1 3.2 -0.3 -0.3 1.3 -0.0 -0.5 3.4
Leg fat-free mass (left) 1.7 9.1 29.3 1.2 -5.2 -5.4 0.3 -0.1 -3.1 -1.3 -0.7 -3.5
Trunk fat percentage 0.2 0.7 3.4 0.3 0.4 0.2 -0.1 -0.1 -1.8 -0.5 -0.3 -1.4
Hand grip strength (right) 0.2 0.5 1.2 -0.3 -1.1 -0.9 0.3 1.0 -0.9 -0.1 0.3 0.1
Townsend deprivation index at recruitment 0.4 0.6 2.8 0.5 0.2 0.6 1.1 -0.2 0.1 -0.6 -0.6 -1.7
Current tobacco smoking 0.2 0.4 1.0 1.0 0.6 -0.1 -0.5 -0.5 0.9 -0.3 -0.1 -0.7
Average weekly fortified wine intake 0.7 0.8 2.1 -0.8 -1.2 -1.4 1.1 0.4 -1.4 0.0 0.1 0.5
Maternal smoking around birth 0.5 0.7 5.0 0.3 -0.6 -0.3 2.2 0.3 0.5 0.4 0.8 -0.3
Fed-up feelings 0.7 1.3 4.7 -2.2 -0.4 0.0 -0.2 -0.1 -1.6 -1.2 -0.8 -1.5
Frequency of unenthusiasm / disinterest in last 2 weeks 0.6 0.9 5.5 -0.0 0.7 0.4 0.8 2.4 0.7 -0.6 -0.1 -0.1
Relative age voice broke 0.7 1.1 2.7 -0.8 -0.3 -0.1 -1.6 -0.8 -1.6 1.0 1.0 0.9
Taking other prescription medications 0.4 0.6 1.4 1.1 0.7 0.8 0.7 0.9 -0.6 0.0 0.1 -1.2
Age when periods started (menarche) 0.2 0.5 1.7 -0.3 -1.0 -1.3 0.1 0.3 -0.5 -0.6 -0.9 0.4
Bilateral oophorectomy (both ovaries removed) 0.9 1.1 3.0 -0.4 0.5 0.6 -1.2 -1.4 1.1 -0.5 -1.1 1.7
Heel bone mineral density (BMD) T-score, automated (left) 4.6 10.5 34.3 -1.0 5.9 5.5 -0.8 0.5 3.9 -0.4 -0.6 3.5
Tinnitus: Yes, but not now, but have in the past 0.6 0.6 1.9 1.2 0.1 0.1 0.8 0.1 1.4 -0.0 0.5 -1.1
Qualifications: CSEs or equivalent 0.3 0.4 1.3 0.8 0.0 -0.1 0.7 0.5 1.2 -0.5 -0.4 0.1
Serious illness, injury or assault to yourself 0.7 0.8 2.1 -0.1 -1.4 -1.1 -0.3 -0.3 -0.7 0.7 0.9 -1.3
High blood pressure 1.9 5.3 23.0 -0.7 4.4 4.8 -0.4 -0.1 1.0 0.6 0.5 1.7
Hayfever, allergic rhinitis or eczema 1.2 2.5 11.4 0.7 -2.9 -3.4 -1.2 -0.3 -1.0 0.4 0.2 0.0
Multivitamins +/- minerals 1.3 1.7 3.6 -1.3 -1.0 -1.2 0.3 1.7 -1.3 1.2 1.0 1.9
Stomach or abdominal pain in last month 0.5 0.6 1.7 0.7 0.7 -0.4 1.2 0.4 1.3 -0.4 -0.4 0.6
Supplements: Glucosamine 0.4 0.6 1.1 -0.2 0.4 0.9 0.7 -0.9 0.2 1.0 1.0 -1.0
Diverticular disease/diverticulitis (self-reported) 0.4 0.4 1.5 -1.1 0.0 0.2 0.2 -0.1 1.2 -0.5 -0.9 -0.5
Medication: Atenolol 0.9 1.1 4.5 -1.0 -0.6 -0.3 -0.8 -0.5 -0.4 1.6 2.1 -0.1
Medication: Levothyroxine sodium 1.3 2.2 6.1 0.7 -2.5 -2.5 -0.1 0.9 -2.0 0.1 0.2 -1.5
Sitting height 0.7 5.0 14.9 -1.0 -3.9 -3.6 -0.2 0.4 -2.2 -1.7 -1.5 -2.4
Chronic bronchitis/emphysema (father) 0.3 0.4 1.5 1.2 0.9 0.6 0.3 -0.9 0.2 0.0 -0.0 0.4
High blood pressure (mother) 2.8 3.9 11.1 -3.3 1.0 2.0 -2.0 -0.6 -1.2 -1.0 -1.2 3.3
Body mass index (BMI) 0.3 1.2 8.3 0.9 -0.0 -0.3 0.3 0.5 -1.1 -0.2 0.3 -2.9
Impedance of leg (left) 1.0 4.9 12.8 -2.4 3.3 3.6 -0.1 0.2 1.6 -0.4 -0.7 3.3
Leg predicted mass (left) 1.7 9.1 29.7 1.1 -5.3 -5.5 0.2 -0.1 -3.1 -1.3 -0.8 -3.3
Trunk fat mass 0.3 1.4 5.0 0.4 -0.8 -1.0 0.0 0.0 -2.2 -0.9 -0.6 -2.2
Waist circumference 0.3 1.1 2.9 0.5 0.6 0.2 -0.1 -0.8 -1.6 -1.4 -1.2 -1.7
Number of incorrect matches in round 0.4 0.7 1.5 -0.7 0.9 1.0 -1.2 0.6 0.5 1.0 0.5 0.4
Past tobacco smoking 0.6 1.0 2.6 -1.0 1.0 0.6 -0.3 1.6 -0.3 1.5 1.4 0.1
Alcohol usually taken with meals 0.5 0.8 3.2 -0.7 -1.1 -0.7 -0.8 -0.9 -1.8 0.4 0.4 -0.1
Nervous feelings 0.3 0.5 1.5 -1.1 -0.3 0.0 -0.7 -0.2 -0.1 -1.2 -1.1 -0.3
Frequency of tenseness / restlessness in last 2 weeks 0.6 0.9 2.5 -1.1 1.0 0.5 1.1 1.6 0.6 -0.5 -0.3 0.8
Hearing difficulty/problems with background noise 0.8 1.3 4.2 0.7 -0.7 -0.1 0.6 -0.5 2.0 1.8 1.6 0.4
Hair/balding pattern: Pattern 2 1.0 1.2 4.9 0.4 -1.3 -1.1 -0.6 -1.4 -0.6 -0.1 0.3 -2.2
Had menopause 1.0 1.2 5.2 0.3 0.3 0.8 -1.1 -2.3 -0.1 1.2 1.3 -1.0
Had other major operations 1.7 2.1 7.2 0.5 -2.7 -2.6 0.7 -1.2 -0.5 0.4 0.5 -1.4
Forced vital capacity (FVC) 0.9 3.4 7.7 -0.7 -0.8 -1.2 2.1 2.3 1.9 -2.8 -2.5 -0.1
Heel bone mineral density (BMD) T-score, automated (right) 4.5 10.2 33.2 -1.1 5.8 5.5 -0.7 0.1 3.6 0.2 0.1 3.8
Ever unenthusiastic/disinterested for a whole week 1.7 2.1 4.5 0.9 -2.0 -2.1 1.0 1.8 -1.0 0.8 1.3 -1.3
Qualifications: None of the above 0.4 0.9 4.3 -0.1 1.4 0.9 0.8 2.1 -0.0 -0.1 -0.4 0.2
Financial difficulties in last 2 years 0.5 0.6 2.7 0.1 1.1 0.6 -0.4 -1.6 0.7 0.3 0.7 -0.5
Mouth/teeth dental problems 0.6 0.9 3.2 -0.7 -0.8 -0.7 0.8 1.0 -1.8 -0.1 -0.2 1.3
Heart attack 1.1 1.4 4.6 -0.7 -1.6 -1.1 2.1 1.4 0.5 0.3 0.5 -1.1
Allergy 1.7 4.0 14.6 -0.8 3.4 3.8 1.7 1.0 2.3 0.1 0.3 0.2
Pain all over the body in last month 1.6 1.7 5.0 0.7 -0.3 -0.5 2.0 1.1 -0.2 2.0 2.2 0.2
Diabetes (self-reported) 0.2 0.3 0.9 0.7 -0.3 -1.0 -0.3 -0.9 0.8 0.2 0.2 -0.4
Hayfever/allergic rhinitis (self-reported) 1.2 1.5 4.1 1.2 -2.0 -1.8 -0.0 0.6 -1.4 -1.0 -1.4 0.4
Medication: Ramipril 0.2 0.3 0.9 -0.3 0.3 0.2 -0.9 -0.7 0.5 0.7 0.3 -0.4
Medication: Simvastatin 0.9 1.4 4.3 2.1 1.6 1.5 0.2 -0.1 1.3 0.5 0.7 -0.9
Fluid intelligence score 0.5 1.1 2.7 1.1 -1.6 -1.6 0.4 -1.4 -0.0 -0.6 -0.6 1.0
Illnesses of siblings 2.0 2.8 9.9 -0.3 -2.8 -3.1 -0.5 1.3 -1.8 -0.9 -0.9 -0.7
Neuroticism score 0.8 1.7 5.0 -2.2 -0.4 -0.1 -0.2 -0.0 -0.9 -2.2 -1.8 1.0
Weight 0.8 3.8 10.6 0.4 -2.8 -2.9 0.2 0.2 -2.4 -1.1 -0.7 -3.3
Impedance of arm (right) 0.3 1.3 5.8 0.3 1.3 1.4 -0.1 -1.3 0.0 0.4 -0.0 2.4
Arm fat percentage (right) 0.2 0.9 4.8 1.0 0.7 0.3 0.8 0.1 -1.0 0.3 0.5 -2.2
Trunk fat-free mass 1.5 8.3 26.4 0.3 -5.1 -5.1 1.1 0.7 -2.0 -1.8 -1.3 -3.4
Hip circumference 0.8 3.3 10.6 -0.4 -1.9 -2.2 0.8 0.8 -2.4 -1.5 -1.0 -3.3
Time employed in main current job 2.3 2.6 7.2 -0.7 1.9 1.3 -0.2 -0.1 2.6 1.5 1.2 -2.7
Alcohol intake versus 10 years previously 2.5 3.8 15.9 4.0 0.1 -0.2 -0.3 -3.0 0.1 -0.8 -0.7 -2.8
Father’s age at death 0.2 0.3 0.7 -0.7 -0.7 0.0 -0.3 0.7 0.8 0.4 -0.0 0.1
Worrier / anxious feelings 0.5 0.9 4.5 -2.1 1.2 1.1 0.7 0.3 0.1 -0.1 0.4 0.6
Frequency of tiredness / lethargy in last 2 weeks 0.3 0.4 1.3 -1.0 1.1 0.7 0.9 0.3 0.2 -0.3 -0.1 0.0
Falls in the last year 0.7 0.9 3.0 -0.4 -0.7 -0.7 1.7 0.9 0.8 1.0 1.1 -0.2
Hair/balding pattern: Pattern 3 0.8 1.2 2.5 -1.4 1.0 1.0 -1.4 0.7 -0.9 0.8 0.5 1.6
Number of live births 0.9 1.3 3.0 -0.7 -1.3 -1.3 1.4 0.4 0.1 1.7 1.4 -0.9
Forced expiratory volume in 1-second (FEV1) 1.2 4.1 9.7 -1.3 0.0 -0.7 2.5 2.9 1.8 -3.1 -2.8 0.0
Pulse rate 1.6 2.7 8.2 -1.3 -2.3 -1.8 0.4 1.4 -2.9 -0.3 -0.7 1.8
Happiness 0.2 0.2 0.7 0.5 -0.1 0.0 -0.1 -0.5 0.8 -0.4 -0.3 -0.7
Noisy workplace 0.7 0.8 1.8 -0.2 1.0 1.0 0.9 1.4 0.9 -0.8 -0.6 -0.8
Qualifications: A levels/AS levels or equivalent 0.4 0.9 2.5 0.1 -1.5 -1.1 -0.4 -1.6 -1.2 -0.6 -0.5 -0.2
Serious illness, injury or assault of a close relative in last 2 years 0.4 0.5 1.8 -0.6 -1.3 -1.1 -0.6 0.3 -0.2 0.3 0.4 0.6
Mouth/teeth dental problems: Dentures 1.5 2.6 12.9 1.6 0.0 0.0 -1.7 -3.6 1.4 -0.3 -0.3 -1.6
Asthma 0.7 1.3 3.1 0.7 -1.6 -1.6 -0.6 -0.9 -1.8 -1.0 -1.0 -0.2
Medication: Ibuprofen (e.g. Nurofen) 0.4 0.5 1.5 0.2 0.6 0.5 0.3 0.7 -0.2 -0.8 -1.0 -1.2
Medication: Cholesterol lowering 1.0 1.6 3.0 1.6 1.7 1.6 -0.4 0.1 1.7 1.3 1.0 0.4
Depression (self-reported) 0.8 0.9 2.3 -1.5 1.0 0.7 -1.4 -1.3 -0.3 -0.6 -0.5 -0.2
Medication: Lansoprazole 0.7 0.8 3.2 -1.8 -0.2 -0.6 0.5 1.3 1.4 0.2 0.2 0.1
Prospective memory result 0.7 0.8 3.6 -0.3 0.7 0.2 -0.5 0.4 -0.3 1.9 1.6 -0.2
Lung cancer (father) 1.5 1.8 5.6 -0.9 -1.5 -1.3 -2.4 -2.0 -0.9 -0.6 -0.6 -0.6
Illnesses of mother 2.2 2.8 8.7 3.0 -1.7 -2.4 1.5 -0.3 1.0 0.5 0.6 -1.8
Forced expiratory volume in 1-second (FEV1), Best measure 1.3 4.1 13.6 -1.3 -0.7 -1.3 2.9 3.7 1.1 -2.5 -2.0 0.2
Pulse wave Arterial Stiffness index 1.1 1.3 6.9 -1.2 -0.1 0.0 -1.3 -2.6 1.0 0.4 0.4 0.6
Impedance of arm (left) 0.4 1.8 7.7 -0.0 1.8 2.0 -0.8 -0.9 -0.1 0.5 0.0 2.8
Arm fat mass (right) 0.4 1.7 9.4 0.7 -1.0 -1.2 0.7 0.4 -1.4 -0.6 -0.2 -3.1
Trunk predicted mass 1.4 8.3 26.2 0.2 -5.1 -5.1 1.2 0.7 -2.0 -1.8 -1.3 -3.4
Standing height 1.0 9.8 35.5 -1.0 -6.0 -5.6 -0.2 -0.5 -2.7 -2.4 -2.2 -1.3
Length of working week for main job 1.4 1.6 4.0 -1.9 0.6 0.3 -2.0 -1.7 1.5 0.7 0.6 -0.5
Exposure to tobacco smoke at home 0.6 0.6 1.8 -1.3 0.2 -0.4 -0.0 -1.4 1.0 0.5 0.5 -0.7
Breastfed as a baby 0.2 0.2 0.6 -0.6 0.2 0.8 -0.6 -0.6 0.0 0.4 -0.2 0.5
Tense / ‘highly strung’ 0.4 0.6 1.7 -1.0 1.3 1.3 -0.3 -0.7 0.7 -0.5 -0.4 0.1
Seen doctor (GP) for nerves, anxiety, tension or depression 0.3 0.4 1.6 -0.5 -0.4 -0.5 -1.0 -1.3 0.7 -0.1 -0.0 0.3
Hair/balding pattern: Pattern 4 0.2 0.6 2.9 0.8 0.9 0.8 1.7 0.3 -0.3 -0.2 -0.1 -0.3
Birth weight of first child 1.9 3.4 9.7 1.1 -2.6 -3.0 1.2 -1.3 0.8 -0.2 -0.3 -3.1
Peak expiratory flow (PEF) 0.9 2.0 5.2 -0.9 0.9 0.2 1.6 2.3 1.2 -2.0 -1.8 0.0
Pulse wave reflection index 1.1 1.3 4.7 0.0 0.3 0.2 -1.3 -2.2 0.9 0.9 1.2 -1.4
Ever highly irritable/argumentative for 2 days 0.9 1.1 5.5 0.7 -1.1 -1.1 -0.9 -0.4 -0.7 -0.0 0.0 -2.3
Loud music exposure frequency 2.0 2.2 6.4 0.3 -2.5 -2.5 1.4 1.5 1.3 -0.3 -0.1 0.9
Qualifications: O levels/GCSEs or equivalent 0.7 1.1 4.3 0.4 -0.2 -0.1 -1.5 -2.1 0.1 1.1 1.3 0.5
Mouth/teeth dental problems: Bleeding gums 1.1 1.4 2.9 -0.2 0.7 0.7 -0.0 0.9 1.7 1.7 1.7 1.3
Blood clot in the leg (DVT) 1.3 1.6 5.8 0.3 -2.1 -2.4 1.2 0.3 0.0 0.9 1.0 -1.0
Medication: Paracetamol 0.4 0.6 2.1 0.9 1.1 0.8 -0.3 -0.5 0.4 -0.0 0.5 -1.5
Headache pain in last month 0.3 0.5 3.0 -0.2 -0.1 -0.9 -1.7 -0.5 -0.6 0.3 -0.1 -0.4
Medication for cholesterol, blood pressure or diabetes 1.0 1.7 4.9 -1.0 -2.2 -2.1 -0.4 -0.8 -0.9 -1.4 -1.1 -0.2
Glaucoma (self-reported) 1.1 1.3 3.7 -1.3 1.0 1.9 -1.1 -1.5 1.0 -0.6 -0.5 -0.1
Gout (self-reported) 1.0 1.4 3.5 -0.2 -0.3 0.2 -0.7 -1.5 -1.1 1.5 1.7 -1.9
Hypothyroidism/myxoedema (self-reported) 0.8 1.5 3.8 1.5 -1.8 -1.6 -0.5 0.7 -1.9 -0.0 0.3 -0.8
Medication: Amlodipine 1.6 2.3 6.0 -2.3 1.5 2.0 -2.4 -1.3 0.2 -0.5 -0.6 0.8
Medication: Ventolin 100micrograms inhaler 0.5 0.6 2.2 -1.1 -0.4 -0.6 0.7 -0.4 -0.1 -0.8 -0.6 -1.5
Birth weight 0.9 1.9 6.0 0.7 -2.4 -2.5 -0.7 -1.4 -0.1 -0.6 -0.5 -1.2
Chronic bronchitis/emphysema (mother) 0.3 0.3 1.6 0.5 0.4 -0.2 0.6 -1.3 -0.4 0.3 0.1 0.4
High blood pressure (siblings) 2.3 3.4 12.4 -0.3 3.0 3.5 -0.9 -2.2 0.3 0.9 0.9 1.2
Forced vital capacity (FVC), Best measure 1.0 3.7 8.2 -0.7 -1.3 -1.8 2.7 2.9 1.6 -2.4 -1.9 0.5
Body fat percentage 0.2 0.6 2.1 0.4 0.9 0.8 -0.0 -0.1 -1.4 -0.2 0.0 -1.4
Leg fat percentage (right) 0.2 0.9 2.7 0.5 1.7 1.5 -0.1 -0.5 -0.4 0.2 0.4 -1.4
Arm fat-free mass (right) 1.3 6.8 19.2 -0.4 -4.4 -4.4 0.4 1.0 -2.3 -1.7 -1.1 -3.5
Exposure to tobacco smoke outside home 1.6 2.1 4.7 -1.9 -0.4 -0.8 1.0 1.7 1.3 1.8 2.2 0.6
Comparative body size at age 10 0.4 1.1 5.1 -0.9 0.5 0.5 1.0 0.1 1.2 0.8 0.6 -2.2
Number of full brothers 0.7 0.9 3.1 1.1 -0.5 -0.3 -0.2 -0.8 0.5 1.8 1.6 -0.3
Worry too long after embarrassment 1.5 2.5 7.1 0.0 -1.1 -0.8 0.9 0.9 -2.2 -2.7 -2.4 -0.9
Seen a psychiatrist for nerves, anxiety, tension or depression 0.8 1.1 3.1 0.1 -0.8 -0.9 -0.4 -0.1 1.4 1.5 1.8 -0.8
Wheeze or whistling in the chest in last year 0.2 0.4 2.5 1.6 0.1 0.2 -0.3 -0.1 -0.1 0.5 0.6 -0.1
Number of children fathered 1.8 2.1 7.3 0.3 2.3 2.7 -1.1 -1.6 1.4 0.6 0.4 -0.1
Reason for reducing amount of alcohol drunk: Health precaution 0.9 1.1 2.9 -1.5 0.3 0.1 1.0 1.7 -0.4 -0.4 -0.5 1.6
Age at first live birth 0.4 0.8 2.6 0.9 0.5 0.4 -0.7 0.6 -0.5 -1.4 -1.6 0.6
Pulse wave peak to peak time 1.1 1.3 6.2 1.3 -0.0 -0.1 1.4 2.5 -1.0 -0.3 -0.3 -0.7
Health satisfaction 0.6 0.7 2.3 1.0 -0.3 -0.4 -0.2 -1.4 -1.5 0.2 0.2 -1.0
Shortness of breath walking on level ground 1.6 1.9 9.1 0.8 -1.1 -1.0 -1.1 -1.6 -3.0 -1.1 -0.8 -0.1
Qualifications: College or University degree 0.2 0.5 1.8 0.1 -0.4 -0.2 1.4 0.2 -0.7 0.7 0.7 1.0
Eye problems/disorders: None of the above 0.4 0.4 2.5 0.1 0.3 -0.2 0.3 0.8 -1.6 -0.3 -0.4 -0.2
Mouth/teeth dental problems: Loose teeth 0.9 1.0 2.5 0.7 -0.6 -1.1 0.9 1.0 -0.2 1.3 1.6 -1.1
Emphysema/chronic bronchitis 0.4 0.4 1.2 -0.5 -0.6 -1.0 -1.1 -0.6 0.2 -0.3 -0.6 -0.2
Medication for pain relief, constipation, heartburn 0.6 1.0 5.5 -0.5 -0.9 -1.0 0.6 0.1 -0.6 0.5 -0.1 2.3
Neck or shoulder pain in last month 0.7 1.0 2.6 1.6 -0.5 -0.2 -1.1 -1.1 -1.6 0.4 0.4 -0.8
Medication: Blood pressure 1.2 2.2 8.2 -0.0 2.8 2.9 -0.1 0.5 -0.2 1.3 1.0 0.3
Angina (self-reported) 0.5 0.6 2.1 0.3 0.5 0.7 1.0 0.7 0.2 -1.4 -1.1 -0.0
Migraine (self-reported) 0.7 0.9 2.9 1.3 0.8 0.6 -1.7 -1.3 -0.3 -0.2 -0.4 0.5
Medication: Ibuprofen 0.7 0.9 3.1 1.0 0.3 0.1 0.6 1.8 -0.2 0.3 0.3 -1.7
Medication: Allopurinol 0.7 0.9 3.1 -0.5 -0.0 0.3 0.2 -0.9 -0.2 1.6 1.8 -1.1
Medication: Omeprazole 1.2 1.4 5.4 -1.0 0.8 0.7 1.8 2.3 -1.1 -0.2 -0.0 -1.0
Medication: Seretide 50 evohaler 0.4 0.5 1.1 1.0 1.1 0.9 0.0 -0.4 0.7 -0.4 -0.4 0.6
Mean time to correctly identify matches 0.9 1.7 7.4 0.4 -0.2 -0.1 -1.8 -2.7 -1.2 -0.1 -0.2 1.6
Heart disease (mother) 1.8 2.2 5.8 -0.2 0.7 1.0 -2.3 -0.9 -2.4 -1.3 -1.5 1.7
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.7 0.8 3.1 0.7 0.9 0.0 -1.8 -1.4 0.8 0.5 0.4 -0.4
Whole body fat mass 0.4 1.5 7.2 0.5 -0.8 -1.0 0.1 0.1 -2.1 -0.5 -0.1 -2.7
Leg fat mass (right) 0.3 1.2 6.7 0.9 -0.6 -0.8 0.0 -0.2 -1.4 -0.4 0.0 -2.6
Arm predicted mass (right) 1.2 6.2 18.1 -0.3 -4.1 -4.3 0.2 0.7 -2.1 -1.7 -1.2 -3.4
Pulse rate, automated reading 0.3 1.0 4.9 0.2 0.2 -0.8 -0.9 1.1 -2.2 0.0 -0.4 0.9
Alcohol intake frequency. 0.7 1.7 8.1 2.2 -0.3 -1.0 -0.5 -0.0 -1.0 -0.1 0.2 -2.8
Comparative height size at age 10 0.6 3.1 7.6 -0.7 -2.8 -2.3 1.5 1.1 -0.7 -2.3 -2.2 -0.4
Number of full sisters 1.3 1.6 4.9 0.9 -1.4 -1.4 2.2 1.8 -0.8 -0.6 -0.7 0.0
Suffer from ‘nerves’ 0.6 1.0 1.6 -1.3 1.2 1.2 -0.4 1.0 1.0 -0.9 -0.5 1.1
Overall health rating 0.2 0.5 1.2 0.2 0.7 0.4 -0.5 0.7 -1.1 0.8 1.0 -0.3
Chest pain or discomfort 0.8 1.2 2.8 0.5 1.2 1.6 -1.1 -0.3 0.2 -1.7 -1.5 0.4
Had major operations 0.8 1.0 2.3 1.0 -1.1 -1.1 -0.8 -0.4 0.6 1.5 1.4 -0.3
Age at last live birth 0.4 0.5 1.4 -0.4 0.9 1.2 -0.0 0.6 0.2 -0.6 -0.8 1.0
Family relationship satisfaction 0.6 0.8 2.9 1.7 -0.5 -0.8 1.5 0.1 -0.2 0.2 0.2 -0.9
Leg pain on walking 0.4 0.5 1.4 -0.4 -0.0 0.1 -0.6 0.1 -0.8 -1.2 -1.2 0.5
Qualifications: NVQ or HND or HNC or equivalent 0.9 1.0 3.2 -0.1 -1.7 -1.8 0.9 1.1 1.0 0.2 0.0 -0.3
Commuting to job workplace: Car/motor vehicle 1.1 1.3 5.3 0.8 2.3 2.2 -0.7 -0.4 0.5 -0.0 0.0 0.2
Illness, injury, bereavement, stress in last 2 years 0.7 0.9 3.6 1.9 0.8 -0.0 0.2 -0.2 1.5 1.1 0.4 0.2
Medication: Aspirin 1.2 1.6 4.4 -0.1 1.8 2.1 -1.3 -1.7 1.0 0.3 0.7 0.3
Supplements: Vitamin C 1.0 1.2 6.8 2.6 0.8 0.4 0.6 -0.2 -0.8 -0.0 -0.2 -1.5
Knee pain experienced in last month 0.8 1.3 3.3 0.5 0.7 -0.2 -0.6 0.7 0.6 1.7 1.8 -1.7
Hypertension (Self-reported) 1.7 4.7 19.8 -0.4 4.2 4.5 -0.2 -0.0 0.7 1.1 1.0 1.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 1.1 1.2 6.5 -1.0 1.3 0.7 0.9 2.5 0.4 -0.1 -0.0 -0.7
Illnesses of father: Heart disease 0.8 1.1 3.0 -0.4 0.9 1.0 1.7 1.1 -0.2 -1.0 -1.4 0.8
Illnesses of siblings: Diabetes 0.7 0.9 2.6 -0.9 1.5 1.6 0.5 0.2 0.8 -0.7 -0.7 0.7
Smoking status: Previous 0.2 0.3 1.0 -0.3 -0.4 0.4 0.5 -1.0 -0.1 -0.7 -0.7 -0.0
Forced expiratory volume in 1-second (FEV1), predicted 1.7 3.5 10.1 -1.3 -3.2 -3.1 -0.0 1.0 -2.8 -0.9 -0.8 0.4
Whole body fat-free mass 1.6 9.2 29.6 0.6 -5.3 -5.4 0.9 0.6 -2.5 -1.6 -1.1 -3.6
Leg fat-free mass (right) 1.7 9.2 29.8 0.8 -5.3 -5.5 0.4 0.3 -3.0 -1.5 -1.0 -3.4
Arm fat percentage (left) 0.2 0.9 4.2 0.8 0.8 0.5 0.2 0.0 -1.3 0.3 0.5 -2.0
Average weekly red wine intake 1.5 2.2 5.1 -1.3 -0.8 -0.2 -2.0 -0.7 -0.8 2.2 2.2 1.5
Handedness (chirality/laterality): Left-handed 0.3 0.4 1.4 -0.5 -0.4 -0.8 -0.4 -0.5 0.6 -0.7 -0.4 1.2
Mood swings 0.2 0.4 1.7 -1.3 0.1 -0.2 0.2 -0.7 -0.3 -0.9 -0.4 0.0
Loneliness, isolation 1.0 1.3 6.9 -2.6 -1.4 -1.4 0.6 0.2 0.4 0.2 0.3 -0.8
Long-standing illness, disability or infirmity 0.9 1.3 3.5 1.3 0.8 0.3 -0.1 -1.5 -0.7 1.5 1.9 -1.0
Ever had bowel cancer screening 0.7 0.8 2.5 -0.7 1.0 1.6 -0.8 -1.0 0.8 0.7 0.5 0.8
Diabetes diagnosed by doctor 0.2 0.3 1.4 0.2 -0.5 -1.2 0.1 -0.7 -0.1 0.1 0.2 -0.0
Ever had stillbirth, spontaneous miscarriage or termination 1.9 2.0 4.9 -1.9 0.9 0.7 -0.2 -0.6 0.2 -1.9 -2.2 1.9
Friendships satisfaction 0.7 0.9 5.3 2.3 0.4 -0.2 0.1 -0.4 1.0 0.8 0.7 0.2
Qualifications: nursing, teaching 0.9 1.4 8.4 1.0 -0.5 -0.5 -0.7 -2.9 -1.3 -0.1 -0.3 -0.0
Commuting to job workplace: Walk 0.8 0.8 2.3 0.5 0.1 -0.4 -0.5 -1.5 0.7 1.4 1.4 -0.3
Eye problems/disorders: Cataract 1.0 1.1 4.0 0.8 -1.0 -0.8 -0.1 0.2 2.0 1.3 1.4 0.5
Mouth/teeth dental problems: Mouth ulcers 0.5 0.8 2.5 0.2 1.1 1.4 0.3 0.8 1.6 0.2 0.3 -0.4
Medication for cholesterol 0.2 0.3 0.8 0.6 0.1 -0.4 -0.5 -0.2 0.6 0.7 0.6 -0.9
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.3 0.3 1.6 -0.2 -0.2 0.0 0.3 1.1 0.0 -0.3 -0.1 -1.2
Back pain experienced in last month 0.5 0.7 3.2 0.1 -1.8 -1.3 -0.3 0.0 -0.8 0.5 0.7 0.2
Mineral and other dietary supplements 0.5 0.7 2.3 -0.2 0.6 -0.0 -0.3 0.7 0.5 -1.5 -1.4 0.9
Breast cancer (self-reported) 1.0 1.2 7.0 0.2 -1.4 -1.2 0.7 -0.5 -0.2 -0.2 -0.1 -2.6
Asthma (self-reported) 0.5 1.1 2.4 0.5 -1.5 -1.4 -0.8 -1.0 -1.5 -0.7 -0.7 0.1
Osteoporosis (self-reported) 0.8 1.0 3.2 0.3 0.2 -0.2 -0.6 0.6 0.5 -1.8 -1.7 1.4
Osteoarthritis (self-reported) 1.2 1.6 4.2 -0.8 1.3 1.3 1.5 1.1 0.3 1.1 1.3 -2.0
Medication: Aspirin 0.8 1.0 3.3 -0.6 1.5 1.8 -1.0 -1.3 0.7 0.0 0.4 0.3
Medication: Gliclazide 0.6 0.7 1.9 1.3 -0.4 -0.9 0.4 -0.2 -0.4 1.4 1.0 0.3
Illnesses of father: None of the above (group 1) 1.0 1.3 4.4 -0.3 -2.1 -1.7 -0.8 -1.4 -0.6 -0.1 -0.0 -1.0
Smoking status: Current 0.4 0.6 1.8 1.3 0.2 -0.6 -0.0 -0.5 1.4 -0.8 -0.5 -0.5
Forced expiratory volume in 1-second (FEV1), predicted percentage 1.3 2.8 6.8 -0.6 2.0 1.2 1.9 2.6 1.8 -1.8 -1.6 0.4
Whole body water mass 1.6 9.1 28.3 0.4 -5.2 -5.3 0.9 0.6 -2.5 -1.8 -1.2 -3.7
Leg predicted mass (right) 1.7 9.2 29.8 0.9 -5.3 -5.5 0.4 0.2 -3.0 -1.5 -0.9 -3.4
Arm fat mass (left) 0.4 1.7 9.5 0.7 -0.9 -1.2 0.4 0.5 -1.5 -0.5 -0.2 -3.1
Number of self-reported non-cancer illnesses 0.6 1.0 3.4 -0.5 1.7 1.8 -0.5 -0.3 -1.2 -0.6 -0.3 -0.0
Average weekly champagne plus white wine intake 1.2 1.7 6.2 -2.5 -0.9 -0.3 0.5 0.8 -2.0 -1.5 -1.1 -0.2
Miserableness 0.5 0.9 3.2 -1.8 0.3 0.4 -1.2 -1.0 -1.2 0.7 0.9 -0.1
Guilty feelings 0.5 0.8 2.3 -0.6 -0.8 -0.3 0.4 1.1 -0.6 -1.5 -1.3 0.5
Wears glasses or contact lenses 1.5 1.7 4.7 0.4 1.1 1.4 -2.1 -2.2 -1.2 -0.6 -0.8 0.6
Ever taken oral contraceptive pill 0.6 0.6 2.1 -0.9 -1.4 -1.2 0.0 0.0 0.5 -0.3 -0.3 1.1
Hearing aid user 0.4 0.5 1.4 -0.0 -0.0 -0.4 -1.0 0.2 -0.8 1.2 0.9 0.6
Mother’s age at death 0.9 1.1 3.0 -1.2 1.2 1.2 0.6 -0.1 -0.3 -1.2 -1.7 1.1
Financial situation satisfaction 0.4 0.5 1.5 -0.1 -0.7 -0.7 0.1 0.3 -0.5 1.1 1.2 -0.1
Tinnitus: Yes, now most or all of the time 1.0 1.1 7.3 2.7 0.7 0.3 -0.5 -1.1 0.6 -0.4 -0.6 -0.4
Commuting to job workplace: Public transport 0.6 0.7 2.7 -0.2 -1.7 -1.3 0.3 0.5 -0.2 -0.3 -0.3 1.1
Eye problems/disorders: Glaucoma 0.6 0.8 3.8 -0.3 0.2 0.9 -1.2 -1.9 0.2 -0.5 -0.4 -0.1
Medication: Blood pressure 0.3 0.6 2.5 -0.8 0.7 1.1 -0.0 -0.8 0.2 0.2 0.4 1.6
Pain type(s) experienced in last month: Hip pain 0.3 0.4 1.7 -0.2 1.3 0.9 -0.0 -0.4 0.4 0.4 0.4 -0.2
Supplements: Fish oil (including cod liver oil) 0.4 0.6 1.2 -1.1 0.2 0.7 -1.1 -0.1 -0.5 1.0 0.6 0.7
High cholesterol (Self-reported) 1.2 2.1 6.9 1.3 2.4 2.6 0.8 0.2 1.7 0.2 0.3 -0.6
Medication: Bendroflumethiazide 1.4 2.1 8.9 -1.1 3.0 2.9 0.8 0.2 -0.0 -0.1 0.1 0.6
Medication: Paracetamol 1.1 1.7 4.7 1.2 1.6 1.1 -0.1 -0.3 1.1 1.1 1.5 -2.2
Medication: Lisinopril 1.3 1.7 5.6 -0.6 2.1 2.4 0.1 0.8 1.8 0.4 0.8 0.6
Medication: Atorvastatin 0.2 0.2 0.5 -0.7 0.1 0.6 0.1 -0.2 -0.1 0.7 0.7 0.5
Illnesses of father: High blood pressure 4.0 5.0 18.0 -0.7 4.2 4.1 -0.2 1.2 1.7 0.7 0.6 2.0
Alcohol drinker status: Never 1.5 1.8 5.2 1.7 0.0 0.1 1.2 1.0 0.4 1.9 2.3 -1.3
Ever smoked 1.2 2.0 5.8 1.2 -1.9 -1.6 -1.2 -2.4 0.0 -1.3 -1.4 0.1
Basal metabolic rate 1.5 8.4 25.7 0.4 -5.0 -5.1 0.9 0.7 -2.5 -1.7 -1.1 -3.7
Leg fat percentage (left) 0.2 0.8 2.4 -0.0 1.6 1.5 -0.1 -0.2 -0.4 -0.1 0.1 -1.5
Arm fat-free mass (left) 1.4 7.1 21.0 -0.2 -4.4 -4.6 1.0 0.9 -1.9 -1.8 -1.3 -3.7
Number of operations (self-reported) 1.8 2.7 10.5 0.9 -3.2 -3.2 0.8 -0.8 -0.1 -0.3 -0.5 -1.0
Average weekly beer plus cider intake 0.4 0.6 2.7 -0.7 0.9 0.3 1.1 -0.1 1.6 0.2 0.6 0.2
Irritability 0.7 1.2 3.3 -0.0 -0.3 -0.2 -1.2 -0.7 0.3 -1.7 -1.4 1.8
Risk taking 0.4 0.5 2.2 0.2 0.6 0.2 -1.0 -1.5 0.8 0.6 0.6 0.1
Ever had prostate specific antigen (PSA) test 1.5 1.7 4.4 -2.1 -1.1 -0.6 -0.0 0.8 0.4 1.7 1.7 1.7
Fractured/broken bones in last 5 years 0.9 1.2 4.9 1.1 -0.8 -1.3 2.2 1.3 -0.5 -0.2 -0.4 -0.6
Age started oral contraceptive pill 1.1 1.4 4.9 2.2 0.8 1.3 -0.5 -1.2 0.9 0.8 1.0 -0.8
Diastolic blood pressure, automated reading 1.7 5.4 21.8 -1.6 4.5 4.7 0.1 0.7 -0.9 -0.5 -0.6 1.2
Ever depressed for a whole week 0.4 0.5 1.8 -0.1 -0.7 -0.8 1.3 1.1 0.1 -0.5 -0.0 -0.7
Unable to work because of sickness or disability 0.8 1.0 2.6 1.0 1.6 1.5 -0.5 -0.6 -0.3 0.4 0.7 -1.6
Commuting to job workplace: Cycle 1.5 1.8 5.1 0.4 -0.5 0.3 -2.1 -0.3 -1.2 -2.2 -2.3 0.4
Myopia 1.3 1.8 6.2 -1.3 -0.7 -0.4 -2.1 -0.2 -2.5 1.3 1.1 0.9
Vascular/heart problems diagnosed by doctor 1.4 3.7 17.8 0.6 -3.5 -4.2 0.3 -0.0 -0.8 -0.2 -0.2 -1.5
Cholesterol lowering medication 0.1 0.2 0.6 0.1 -0.4 0.0 0.8 -0.2 -0.5 -0.1 0.2 -0.6
Medication: Omeprazole (e.g. Zanprol) 0.7 0.9 2.8 -0.1 0.4 0.2 1.2 1.7 -1.2 -0.3 0.2 -1.5
Pain experienced in last month 0.3 0.5 1.4 -0.4 0.3 1.2 1.1 -0.5 0.3 -0.8 -0.5 -0.5
Supplements: Calcium 0.8 0.8 2.9 -0.3 -1.5 -1.7 0.2 1.0 -0.6 -0.3 -0.4 -0.9
Basal cell carcinoma (self-reported) 1.9 2.2 6.7 -1.7 0.0 0.6 1.6 1.0 -0.4 -2.6 -2.5 -0.4
Heart attack/myocardial infarction (self-reported) 1.2 1.6 4.5 -0.5 -2.0 -1.6 2.1 1.1 0.2 0.2 0.3 -1.4
Deep venous thrombosis (DVT) (self-reported) 1.4 1.8 7.2 0.6 -2.4 -2.7 0.7 -0.1 -0.2 0.6 0.8 -1.4
Heart disease (siblings) 1.1 1.3 3.8 0.3 0.8 1.0 -0.2 -2.0 1.7 1.1 0.9 -1.1
Alcohol drinker status: Previous 1.4 1.6 4.0 -1.1 -1.6 -1.6 0.0 2.0 -1.9 0.0 -0.2 0.3
Pack years of smoking 0.4 0.6 3.5 1.1 0.4 0.2 1.9 0.0 0.7 -0.2 0.4 -0.2
Impedance of whole body 0.7 3.3 11.8 -1.2 2.7 2.8 -0.5 -0.8 0.6 -0.1 -0.6 3.4
Leg fat mass (left) 0.3 1.2 7.0 0.6 -0.6 -0.8 0.1 -0.0 -1.4 -0.4 0.0 -2.6
Arm predicted mass (left) 1.5 7.5 22.1 -0.1 -4.6 -4.7 1.1 0.9 -1.9 -2.0 -1.4 -3.6