Best TWAS P=1.38e-13 · Best GWAS P=2.52e-13 conditioned to 0.00242
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Aorta | GUCY1A3 | 0.29 | 0.12 | lasso | 6 | 0.19 | 1.7e-10 | 6.7 | -7.4 | 1.7e-13 | -0.69 | 0.11 | 0.89 | FALSE |
| 2 | GTEx | Artery Aorta | RP11-588K22.2 | 0.22 | 0.11 | lasso | 11 | 0.11 | 1.6e-06 | 6.7 | -7.4 | 1.4e-13 | -0.69 | 0.10 | 0.87 | TRUE |