Best TWAS P=1.39e-07 · Best GWAS P=2.65e-07 conditioned to 0.586
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | PMS2P3 | 0.15 | 0.12 | lasso | 3 | 0.10 | 9.8e-09 | -5.1 | -5.1 | 3.0e-07 | 0.99 | 0.00 | 1.00 | FALSE |
| 2 | GTEx | Artery Coronary | STAG3L1 | 0.28 | 0.13 | lasso | 4 | 0.17 | 1.8e-06 | -4.9 | -5.1 | 2.7e-07 | 0.86 | 0.00 | 0.98 | FALSE |
| 3 | GTEx | Cells Transformed fibroblasts | PMS2P3 | 0.23 | 0.15 | lasso | 6 | 0.15 | 1.4e-11 | -5.1 | -5.2 | 1.6e-07 | 0.97 | 0.00 | 1.00 | FALSE |
| 4 | GTEx | Esophagus Muscularis | TRIM73 | 0.12 | 0.07 | lasso | 2 | 0.05 | 3.5e-04 | -5.1 | -5.2 | 2.5e-07 | 1.00 | 0.00 | 0.99 | FALSE |
| 5 | GTEx | Nerve Tibial | PMS2P3 | 0.29 | 0.13 | enet | 4 | 0.18 | 1.1e-12 | -4.9 | -5.2 | 2.0e-07 | 0.90 | 0.00 | 0.99 | FALSE |
| 6 | GTEx | Ovary | RHBDD2 | 0.55 | 0.00 | enet | 24 | 0.07 | 7.6e-03 | -4.9 | 5.2 | 1.8e-07 | -0.54 | 0.02 | 0.31 | FALSE |
| 7 | GTEx | Stomach | PMS2P3 | 0.16 | 0.07 | lasso | 5 | 0.09 | 3.7e-05 | -4.9 | -5.2 | 2.1e-07 | 0.94 | 0.00 | 0.99 | FALSE |
| 8 | The Cancer Genome Atlas | Uterine Corpus Endometrial Carcinoma | PMS2L3 | 0.23 | 0.14 | lasso | 2 | 0.14 | 1.3e-04 | -5.0 | -5.3 | 1.4e-07 | 0.94 | 0.00 | 0.69 | TRUE |