Hub : Genes

RHBDD2

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 GTEx Artery Aorta 0.224 0.0760 3.4e-03 0.064 NA 0.041 NA 0.057 2.0e-04 NA 2.6e-03 NA 4.6e-04
2 GTEx Cells Transformed fibroblasts 0.187 0.0660 5.8e-03 0.085 NA 0.065 NA 0.081 6.2e-07 NA 1.3e-05 NA 1.2e-06
3 GTEx Colon Sigmoid 0.229 0.0850 8.2e-03 0.119 NA 0.057 NA 0.100 5.5e-05 NA 4.4e-03 NA 2.2e-04
4 GTEx Esophagus Mucosa 0.077 0.0390 6.6e-03 0.006 NA 0.043 NA 0.023 1.1e-01 NA 7.1e-04 NA 1.0e-02
5 GTEx Nerve Tibial 0.145 0.0709 6.4e-03 -0.002 NA -0.004 NA -0.003 4.5e-01 NA 8.1e-01 NA 6.0e-01
6 GTEx Ovary 0.555 0.0980 5.8e-04 -0.002 NA 0.072 NA 0.054 3.6e-01 NA 7.6e-03 NA 1.8e-02
7 METSIM Adipose 0.215 0.0420 1.3e-13 0.054 0.126 0.136 0.133 0.119 1.6e-08 2.6e-18 9.9e-20 2.9e-19 2.5e-17
8 YFS Blood 0.165 0.0279 0.0e+00 0.090 0.164 0.155 0.165 0.152 5.3e-28 2.4e-51 1.9e-48 1.2e-51 2.0e-47

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
Bipolar Disorder (2018) 0.9 1.4 4.5 0.4 0.3 -2.0 -1.1 -2.1 0.1 -0.8 -0.6
Bipolar Disorder or Schizophrenia 0.4 1.0 1.8 -1.3 -1.3 -1.0 -1.1 -0.3 0.3 -1.3 -0.4
Depressed Affect (Nagel 2018) 1.4 2.9 7.8 -0.1 2.3 1.6 -2.0 -2.8 -1.2 -1.5 -0.5
Depression (Nagel 2018) 0.6 0.9 2.0 0.3 0.8 0.4 -1.1 -1.4 -0.7 -1.1 -1.3
Intelligence (Savage-Jansen 2018) 0.7 2.2 5.0 -0.4 0.9 -0.1 1.7 2.0 -2.0 0.8 2.2
Neuroticism (Nagel 2018) 1.3 3.0 7.1 -0.5 2.7 2.1 -1.3 -2.6 -1.8 -0.7 0.1
Schizophrenia (2018) 0.6 1.2 3.7 -1.9 -1.9 0.3 -0.6 1.0 0.4 -0.9 -0.2
Schizophrenia vs Biploar Disorder 0.6 0.8 1.9 -1.2 -1.2 1.4 -0.8 0.0 -0.1 -1.0 -0.4
Worry (Nagel 2018) 0.8 1.8 3.7 1.2 1.9 -0.2 0.3 -1.9 -1.9 0.9 1.0
Alzheimer’s Disease (in mother) 0.7 0.9 2.6 -0.9 -0.1 -0.3 -1.6 -0.9 -1.4 -0.7 -0.4
Alzheimer’s Disease (in father) 0.5 0.5 1.2 0.9 0.6 -0.3 0.3 -0.8 0.2 1.1 1.0
Alzheimer’s Disease (including proxy) 0.3 0.5 2.2 0.1 0.0 -0.2 -0.6 -1.5 -0.9 0.5 0.5
Crohns Disease (2017) 0.2 0.4 1.1 -0.5 -0.3 -0.2 0.4 -1.0 -1.0 0.9 0.4
Irritable Bowel Disease (IBD) 0.7 1.7 4.1 0.2 0.9 0.7 1.6 -0.9 -1.2 2.0 1.8
Ulcerative Colitis (UC) 1.1 2.0 3.7 0.4 1.3 1.2 1.7 -0.6 -1.7 1.8 1.9
Major Depression (MDD) 0.9 1.1 3.1 -1.5 0.3 0.3 -1.5 0.0 0.5 -1.8 -0.8
Reaction Time 1.7 3.3 7.0 -0.8 -1.6 -2.0 -0.7 -2.2 -2.6 -2.0 -1.6
Verbal and Numeric Reasoning (VNR) 0.7 1.7 5.6 -1.0 -0.1 -0.1 1.2 1.8 -2.4 0.6 1.4
Breast Cancer 0.4 1.1 4.4 0.5 -1.4 -0.9 -0.1 0.9 -2.1 -0.1 0.2
Ovarian Cancer 0.4 0.5 2.1 -0.4 -0.3 0.6 1.4 -1.2 0.2 0.2 -0.1
Prostate Cancer 0.8 1.2 2.6 -1.6 0.2 0.1 0.0 1.4 -1.1 -1.0 1.6
Age at First Birth 0.8 1.2 6.8 -0.6 -0.7 -0.9 -0.2 -0.2 -2.6 -0.8 -0.3
Bipolar Disorder (2011) 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
Body Mass Index (BMI) (2010) 2.5 3.5 13.9 2.3 0.4 0.8 2.1 0.7 3.7 1.6 -0.4
Coronary Artery Disease (CAD) 0.9 1.1 4.0 1.0 0.7 -2.0 -0.0 0.0 1.8 0.0 -0.4
Crohns Disease (2012) 0.6 1.0 4.7 0.0 -0.9 -1.0 -0.5 0.0 -2.2 -0.1 -1.1
Mean Putamen Volume 1.7 2.0 7.3 -0.8 -0.8 1.0 1.5 2.7 0.6 1.4 1.3
Fasting Glucose 0.4 0.5 1.7 -0.1 -1.3 1.2 -0.0 0.5 -0.7 -0.2 -0.5
HbA1C 0.5 0.5 1.8 0.1 -0.5 0.6 -1.0 -0.1 -0.3 -1.4 -0.8
HDL Cholesterol 1.8 3.0 6.6 0.0 -1.6 -0.3 -2.5 -0.2 -1.8 -2.6 -2.4
LDL Cholesterol 0.9 1.4 4.7 -0.5 0.3 0.9 1.5 0.8 -0.8 1.4 2.2
Lupus 0.2 0.3 0.8 0.7 -0.4 0.1 0.9 0.6 0.2 0.2 0.2
Neuroticism (2016) 1.1 1.6 4.0 -2.0 -0.2 0.8 -1.4 -0.9 -1.5 -1.4 -1.0
Primary Biliary Cirrhosis 0.6 0.9 2.2 -0.2 1.0 0.6 -1.5 -0.4 -1.4 -1.3 -0.1
Rheumatoid Arthritis 0.4 0.6 1.1 -0.6 0.2 -0.9 1.1 0.3 -0.9 0.6 1.0
Schizophrenia (2014) 0.3 0.8 2.4 -1.5 -1.4 -0.0 -0.6 0.6 -0.0 -0.9 -0.5
Triglycerides 1.9 3.1 7.3 -0.1 2.0 -0.2 2.5 0.6 1.1 2.7 2.3
Type 2 Diabetes (T2D) (2012) 1.4 1.6 6.1 -0.6 -0.4 -0.3 -1.1 0.0 -1.9 -1.2 -2.5
Ulcerative Colitis 0.8 1.1 2.7 1.0 1.6 0.4 1.2 0.0 -0.3 1.2 1.4
Blood Eosinophil Count 2.1 16.4 72.2 1.1 4.0 5.8 1.8 -8.5 1.5 -0.4 1.4
Blood Platelet Count 0.3 3.8 12.2 0.7 -1.8 -1.2 3.5 1.4 0.4 2.4 2.3
Blood Red Count 0.2 1.5 4.5 0.8 0.5 -1.0 -0.0 -2.1 1.7 -0.6 -1.5
Blood White Count 1.0 7.3 20.8 -0.7 -2.2 1.1 -2.6 -2.2 2.3 -4.6 -3.8
Heel T-Score 0.4 2.9 6.9 2.5 0.4 -1.9 1.5 -1.5 2.6 0.7 -1.0
BMI 1.9 11.0 64.2 2.2 1.2 -0.7 3.1 0.9 8.0 2.6 0.2
Height 0.1 1.9 8.8 1.7 1.4 0.8 -0.2 0.0 -3.0 0.9 -0.6
Waist Hip Ratio (WHR) 0.2 0.8 1.8 -0.9 0.6 1.1 -0.8 -1.3 -1.2 -0.1 0.7
Systolic Blood Pressure 0.7 3.4 17.3 0.6 0.4 1.6 1.4 0.5 4.2 1.7 1.1
Smoking Status 0.3 0.8 2.6 0.8 0.8 1.0 -0.5 -1.6 1.2 0.1 -0.2
Allergy or Eczema 0.8 2.1 6.0 0.4 2.4 1.7 1.3 -1.0 -0.4 1.6 1.4
Cardiovascular Disease 1.1 3.6 13.5 -0.5 1.2 0.6 2.5 0.8 3.7 1.2 2.1
Hypothyroidism (self reported) 0.3 0.7 2.8 0.4 -0.9 -0.6 -0.9 -0.3 -0.4 -0.7 -1.7
Respiratory disease 0.6 1.3 2.3 -1.3 -1.2 0.6 -1.4 -0.4 0.8 -1.5 -1.3
Type 2 Diabetes (T2D) (2018) 0.6 1.1 3.0 0.6 -0.2 -1.1 1.7 1.6 0.5 1.0 -0.6
Lung FEV1/FVC ratio 0.1 0.7 3.3 -0.3 1.8 -0.5 -0.0 -0.7 1.0 -0.1 0.9
Lung FVC 0.4 1.8 4.4 -1.2 -0.4 -0.9 -2.0 -0.5 0.1 -1.9 -2.1
Neuroticism 1.0 2.5 10.0 -0.3 3.2 2.2 -1.0 -1.8 -0.5 0.2 0.7
Chronotype (morning person) 0.8 1.8 7.5 -0.3 -0.4 0.4 -1.2 -1.3 2.7 -1.1 -1.4
Hair Pigment 0.0 0.3 0.8 -0.9 0.0 -0.3 -0.5 -0.4 0.6 -0.6 -0.7
Tanning 0.1 1.3 3.2 -0.8 -0.1 -1.8 -1.7 0.4 -0.4 -1.7 -0.5
Hand grip strength (left) 0.6 1.5 5.0 0.2 -0.7 -1.3 -1.7 -0.9 -2.2 -0.8 -0.6
Number of treatments/medications taken 0.8 1.4 4.5 0.2 2.1 0.3 1.6 0.2 1.0 0.8 1.5
Average weekly spirits intake 0.9 1.1 4.7 0.8 0.3 0.5 -0.4 -1.5 -2.2 0.3 0.7
Sensitivity / hurt feelings 1.3 2.3 7.8 -1.4 1.1 2.8 -1.4 -0.6 -2.0 -1.0 -0.2
Frequency of depressed mood in last 2 weeks 0.5 0.8 4.1 0.6 2.0 0.8 0.0 -0.9 0.3 0.4 0.1
Hearing difficulty/problems: Yes 0.7 1.1 4.9 0.2 1.0 2.2 -0.7 0.5 1.5 -0.3 -0.2
Relative age of first facial hair 0.7 1.5 6.2 1.3 0.0 1.4 -1.0 -0.4 -2.5 0.9 -0.3
Other serious medical condition/disability diagnosed by doctor 0.6 0.8 4.6 0.4 2.1 0.4 0.4 -0.5 0.9 0.3 0.2
Ever used hormone-replacement therapy (HRT) 0.4 0.5 1.1 -0.5 -0.5 0.9 0.7 1.1 -0.4 -0.7 -0.6
Ever had hysterectomy (womb removed) 0.4 0.4 2.0 -0.4 -0.9 0.4 0.0 -1.4 0.2 0.1 0.3
Systolic blood pressure, automated reading 2.0 5.9 27.2 0.6 1.2 0.1 2.6 0.1 5.2 2.8 2.0
Eye problems/disorders: Diabetes related eye disease 0.2 0.2 0.7 -0.1 0.9 -0.6 0.0 0.2 0.2 -0.7 -0.5
Angina 1.1 1.4 6.0 0.4 -1.0 -0.3 0.2 0.9 2.5 -0.4 -1.8
Medication for hormone replacement therapy 1.3 1.5 4.5 -0.5 -1.2 0.5 -0.7 1.0 -0.5 -1.9 -2.1
Vitamin and mineral supplements 0.5 0.7 3.1 -1.1 -0.1 1.8 -0.1 0.0 0.5 0.2 1.0
Supplements: Zinc 0.6 0.6 2.2 0.2 -0.2 -1.1 -0.4 -0.8 -1.5 0.1 -0.8
Medication: Co-codamol 0.6 0.6 1.5 -0.0 0.1 -1.2 -1.2 0.0 0.5 -1.1 -0.9
Medication: Metformin 0.9 1.3 3.1 1.1 0.3 -1.7 1.7 0.2 1.1 1.4 0.4
Diabetes (father) 1.2 1.5 6.5 2.5 -0.4 -1.4 0.4 0.1 -1.4 0.8 -0.6
Diabetes (mother) 1.8 2.3 5.3 0.2 2.0 2.3 1.5 -0.5 0.9 1.4 1.9
Severe depression (siblings) 2.6 2.9 9.6 0.2 0.6 -0.8 -3.1 -1.4 -0.1 -2.5 -2.2
Pack years adult smoking proportion 0.3 0.4 0.9 0.6 0.8 0.1 -0.8 -0.4 1.0 -0.7 -0.5
Impedance of leg (right) 2.5 12.0 38.3 -2.7 -2.1 1.0 -4.3 -1.6 -6.2 -4.4 -2.3
Leg fat-free mass (left) 0.6 3.1 11.2 1.4 1.4 -1.1 1.6 1.3 3.4 2.1 0.0
Trunk fat percentage 1.0 3.9 21.4 1.0 1.9 -0.4 1.5 0.9 4.6 1.4 -0.5
Hand grip strength (right) 0.4 1.0 3.3 0.5 -0.3 -1.1 -1.4 -0.1 -1.8 -0.7 -1.0
Townsend deprivation index at recruitment 1.5 2.1 5.0 -1.4 -1.1 0.7 -2.2 -1.0 0.8 -1.6 -1.8
Current tobacco smoking 0.5 0.9 2.6 -0.6 0.2 1.6 -1.0 -1.0 0.5 -1.3 -0.6
Average weekly fortified wine intake 0.8 0.9 2.5 0.5 -1.1 -0.4 0.9 1.6 -1.2 1.0 0.0
Maternal smoking around birth 1.5 2.2 9.5 0.8 -0.6 1.2 -1.2 -0.5 3.1 -1.2 -1.6
Fed-up feelings 1.2 2.2 10.3 -0.6 3.2 1.2 -1.1 -2.0 0.1 -0.4 0.6
Frequency of unenthusiasm / disinterest in last 2 weeks 0.5 0.7 1.3 -0.4 1.1 0.8 -0.8 -1.1 -0.2 -1.1 -0.7
Relative age voice broke 1.7 2.6 8.0 -1.6 -1.3 2.4 -0.7 1.4 -2.8 -0.0 0.6
Taking other prescription medications 0.7 1.1 2.1 1.4 1.4 0.2 0.8 0.1 1.3 1.4 0.3
Age when periods started (menarche) 0.7 1.7 4.3 0.9 1.0 1.6 -0.9 2.1 -2.0 0.3 0.4
Bilateral oophorectomy (both ovaries removed) 1.0 1.1 3.7 -0.4 -1.4 -1.0 -0.1 0.5 0.7 -1.3 -1.9
Heel bone mineral density (BMD) T-score, automated (left) 0.8 1.8 8.2 0.9 0.6 -1.0 0.7 -2.9 1.7 0.5 0.5
Tinnitus: Yes, but not now, but have in the past 2.4 2.6 11.2 0.3 -1.2 -0.8 -1.6 -1.4 -0.2 -1.6 -3.4
Qualifications: CSEs or equivalent 0.9 1.3 4.8 -1.5 1.1 2.2 -0.4 -0.6 0.1 -0.7 0.9
Serious illness, injury or assault to yourself 1.2 1.5 4.3 -2.0 -1.0 -1.0 -0.7 2.1 -0.0 -1.0 -0.6
High blood pressure 1.6 4.5 12.5 0.2 1.0 -0.8 3.2 0.4 3.5 2.1 2.6
Hayfever, allergic rhinitis or eczema 0.6 1.3 5.5 -0.5 1.6 2.3 0.4 -0.9 -0.7 0.2 0.7
Multivitamins +/- minerals 1.0 1.3 5.1 1.4 1.3 -2.2 0.9 -0.4 -0.3 0.5 0.7
Stomach or abdominal pain in last month 0.5 0.6 2.7 -0.2 0.7 0.8 -0.5 -0.2 -1.6 -0.7 -0.7
Supplements: Glucosamine 1.4 1.8 5.7 0.6 0.7 -0.5 2.4 1.1 -0.3 2.0 1.5
Diverticular disease/diverticulitis (self-reported) 0.3 0.3 1.1 0.7 0.6 -0.4 -0.1 1.0 0.1 -0.3 -0.8
Medication: Atenolol 2.7 3.3 7.7 0.2 -0.1 -0.9 2.8 1.8 1.2 2.5 2.6
Medication: Levothyroxine sodium 0.4 0.7 2.7 0.7 -0.4 -1.1 -0.7 -0.5 0.2 -0.6 -1.6
Sitting height 0.3 2.3 4.8 -1.6 -0.9 1.4 -2.2 1.3 -1.5 -1.4 -1.5
Chronic bronchitis/emphysema (father) 1.5 1.8 5.6 1.3 1.5 0.3 -0.2 2.0 2.4 0.5 -0.2
High blood pressure (mother) 0.8 1.1 4.9 -0.2 -0.7 0.9 2.2 0.8 0.1 1.0 0.9
Body mass index (BMI) 1.8 7.6 45.7 1.3 1.8 -1.2 2.2 0.5 6.8 1.9 0.1
Impedance of leg (left) 1.9 9.3 33.8 -2.4 -1.7 0.7 -3.6 -1.0 -5.8 -3.6 -1.9
Leg predicted mass (left) 0.6 3.2 11.5 1.5 1.5 -1.1 1.6 1.2 3.4 2.1 0.0
Trunk fat mass 1.0 4.4 21.7 1.3 1.8 -0.6 1.8 1.0 4.7 1.8 -0.3
Waist circumference 1.3 4.6 26.3 0.9 1.6 -0.3 1.8 -0.0 5.1 1.9 0.4
Number of incorrect matches in round 1.2 2.0 4.7 0.8 -1.3 0.1 2.1 -1.1 2.2 1.4 1.1
Past tobacco smoking 0.6 1.1 4.5 -0.5 -1.0 0.2 -0.1 2.1 -1.3 -0.9 -0.9
Alcohol usually taken with meals 2.2 3.6 8.5 -0.5 -2.7 -2.5 1.6 1.3 -2.9 1.1 0.9
Nervous feelings 0.6 1.1 4.6 0.9 2.1 -0.1 -0.4 -0.6 -1.5 0.7 -0.4
Frequency of tenseness / restlessness in last 2 weeks 0.7 1.1 3.2 0.2 1.3 1.4 -0.1 -1.2 -1.8 -0.3 -0.6
Hearing difficulty/problems with background noise 0.4 0.7 1.9 1.1 0.2 1.4 -0.4 0.8 0.7 -0.1 -1.1
Hair/balding pattern: Pattern 2 0.5 0.6 3.7 0.2 0.0 -0.1 0.4 -0.4 1.9 0.8 -0.0
Had menopause 0.2 0.3 0.9 0.6 0.1 -0.9 0.1 -0.3 0.8 -0.1 -0.1
Had other major operations 1.0 1.2 4.5 -2.1 0.6 0.4 -1.6 0.7 0.4 -0.9 -0.8
Forced vital capacity (FVC) 0.7 2.6 6.3 -1.9 -0.9 -0.2 -2.4 1.1 -2.5 -1.4 -1.1
Heel bone mineral density (BMD) T-score, automated (right) 0.5 1.1 3.9 0.5 0.3 -1.7 0.7 -2.0 1.1 0.4 0.2
Ever unenthusiastic/disinterested for a whole week 0.3 0.3 1.5 0.7 0.4 0.0 -0.1 -1.2 -0.4 0.0 -0.6
Qualifications: None of the above 1.4 3.1 8.2 -0.5 -0.0 -0.7 -2.9 -2.5 1.6 -2.3 -1.2
Financial difficulties in last 2 years 0.5 0.7 1.4 -0.1 1.2 0.7 -1.1 -1.1 1.1 -0.2 0.3
Mouth/teeth dental problems 0.7 1.1 2.7 1.6 -0.6 -0.3 1.5 -0.9 0.4 1.5 0.6
Heart attack 0.1 0.1 0.4 -0.1 0.3 -0.2 0.0 -0.3 0.6 -0.2 -0.3
Allergy 0.4 0.9 2.8 0.5 -1.5 -1.7 -0.1 1.1 0.0 -0.4 -0.7
Pain all over the body in last month 1.5 1.6 4.5 2.1 -1.0 -1.6 0.9 0.1 0.9 1.4 -1.2
Diabetes (self-reported) 0.7 1.0 3.0 1.1 0.0 -1.1 1.7 0.7 0.8 0.9 -0.8
Hayfever/allergic rhinitis (self-reported) 0.8 1.0 3.1 -0.1 0.1 1.8 1.4 1.5 -0.1 0.9 -0.0
Medication: Ramipril 1.0 1.3 7.8 -0.6 0.2 0.0 0.6 0.9 2.8 -0.3 -1.0
Medication: Simvastatin 1.5 2.2 5.1 1.3 2.3 0.3 1.7 0.9 1.8 1.2 1.6
Fluid intelligence score 0.8 1.7 6.8 -0.8 0.3 -0.6 -0.0 2.3 -2.6 0.1 0.4
Illnesses of siblings 0.9 1.2 4.1 0.4 0.2 -0.6 -1.5 0.4 -2.0 -0.9 -1.3
Neuroticism score 1.3 2.7 7.2 -0.8 2.3 2.7 -1.1 -2.3 -1.3 -0.1 0.5
Weight 0.9 4.5 23.7 1.4 1.8 -0.7 1.6 0.8 4.9 1.9 -0.2
Impedance of arm (right) 0.6 2.9 13.3 -0.6 0.3 2.4 -1.6 0.2 -3.6 -1.0 -0.3
Arm fat percentage (right) 1.4 5.6 30.8 1.3 1.9 -0.1 2.2 0.8 5.5 1.9 -0.1
Trunk fat-free mass 0.2 1.2 3.0 1.3 0.7 -1.1 1.1 0.9 1.1 1.7 0.4
Hip circumference 1.3 5.5 26.7 1.7 1.7 -0.6 2.2 1.1 5.2 2.2 -0.1
Time employed in main current job 1.3 1.5 4.1 0.0 0.8 -1.3 1.0 2.0 0.5 1.7 1.1
Alcohol intake versus 10 years previously 1.0 1.4 4.0 -0.4 -0.2 0.4 -1.9 0.9 0.1 -2.0 -1.6
Father’s age at death 0.6 0.8 2.2 -0.2 -1.5 -1.0 -0.4 -0.4 -1.4 -0.5 -1.0
Worrier / anxious feelings 1.9 3.5 6.9 1.3 2.0 1.0 1.0 -2.2 -2.4 1.8 2.6
Frequency of tiredness / lethargy in last 2 weeks 0.7 1.1 2.1 -1.4 0.2 1.4 -1.0 -0.5 -0.8 -1.2 -1.1
Falls in the last year 1.0 1.4 3.9 -0.4 -0.3 -0.7 -1.5 -0.2 -1.4 -1.4 -2.0
Hair/balding pattern: Pattern 3 0.6 0.9 3.2 -1.3 -0.9 1.0 0.4 1.8 0.6 -0.5 0.2
Number of live births 1.1 1.6 3.3 -1.8 -1.6 0.2 -1.5 -1.2 -0.2 -1.6 -0.9
Forced expiratory volume in 1-second (FEV1) 0.6 2.1 6.1 -1.4 -0.3 -0.5 -2.5 0.9 -2.2 -1.4 -1.0
Pulse rate 0.6 1.0 2.4 0.4 0.6 1.1 1.3 -0.4 1.1 1.5 1.0
Happiness 0.6 0.8 2.1 -0.4 0.4 1.3 -0.7 1.0 -1.5 -0.7 -0.1
Noisy workplace 1.0 1.2 2.6 -0.2 0.6 1.1 -1.3 -1.6 1.5 -1.0 -0.9
Qualifications: A levels/AS levels or equivalent 1.8 4.1 12.6 1.6 1.6 -1.4 1.5 0.5 -3.5 2.1 2.5
Serious illness, injury or assault of a close relative in last 2 years 1.1 1.2 6.6 -0.6 0.1 1.6 -0.5 2.6 -0.3 -0.1 -0.2
Mouth/teeth dental problems: Dentures 0.4 0.6 1.5 -0.1 1.0 -1.2 -0.3 -1.2 0.9 -0.1 0.2
Asthma 0.5 0.9 2.5 -0.5 -0.7 0.6 -1.2 -0.0 0.9 -1.3 -1.6
Medication: Ibuprofen (e.g. Nurofen) 1.2 1.5 2.6 -1.2 -0.2 1.4 -1.4 1.2 -1.6 -0.9 -1.2
Medication: Cholesterol lowering 2.4 3.8 6.1 1.2 2.0 1.0 2.4 1.6 2.4 2.5 2.0
Depression (self-reported) 0.9 1.0 3.6 0.9 1.4 0.5 -0.5 -1.0 1.9 -0.4 -0.4
Medication: Lansoprazole 1.7 1.9 6.1 0.6 0.5 1.1 1.8 1.3 2.5 1.4 0.6
Prospective memory result 1.8 2.2 5.2 -0.3 -2.0 -2.3 -1.5 0.7 -0.1 -1.5 -1.9
Lung cancer (father) 2.0 2.3 9.2 0.6 3.0 -0.4 1.0 0.2 1.7 1.3 1.8
Illnesses of mother 1.3 1.7 4.0 0.3 -0.4 -0.4 -2.0 1.1 -0.6 -2.0 -1.8
Forced expiratory volume in 1-second (FEV1), Best measure 0.9 2.9 8.2 -1.1 -0.5 -0.6 -2.7 -0.1 -2.9 -1.7 -1.7
Pulse wave Arterial Stiffness index 1.6 1.9 3.5 1.1 1.5 -0.6 1.3 -1.9 1.3 1.0 1.8
Impedance of arm (left) 0.8 3.8 17.0 -0.9 -0.0 2.0 -2.2 -0.2 -4.1 -1.7 -0.8
Arm fat mass (right) 1.4 5.9 29.2 1.4 2.1 -0.5 2.4 1.1 5.4 2.2 0.3
Trunk predicted mass 0.2 1.4 3.4 1.3 0.8 -1.1 1.2 0.9 1.1 1.9 0.5
Standing height 0.2 2.1 12.2 0.4 0.5 1.1 -1.2 1.0 -3.5 0.3 -0.4
Length of working week for main job 0.5 0.6 3.1 -0.3 0.2 -0.1 0.4 1.8 -1.0 0.3 0.4
Exposure to tobacco smoke at home 1.3 1.5 3.6 -1.9 -0.6 -0.4 -1.9 0.5 -0.6 -1.6 -1.2
Breastfed as a baby 0.3 0.4 1.9 -0.2 0.4 1.4 -0.5 0.6 -0.5 -0.1 0.3
Tense / ‘highly strung’ 0.5 0.8 5.2 -0.3 0.2 -0.0 -0.3 -0.9 -2.3 -0.2 -0.2
Seen doctor (GP) for nerves, anxiety, tension or depression 1.1 1.7 4.6 -0.6 1.2 0.4 -2.1 -1.8 0.2 -1.8 -0.8
Hair/balding pattern: Pattern 4 0.5 1.3 3.1 -1.5 0.2 -0.2 -1.2 -1.7 0.5 -1.8 -0.5
Birth weight of first child 1.5 2.7 10.1 -1.3 0.5 3.2 -0.1 1.2 -2.8 -0.4 0.6
Peak expiratory flow (PEF) 0.7 1.6 4.0 -1.4 0.2 0.4 -2.0 1.9 -1.3 -1.1 -0.5
Pulse wave reflection index 0.6 0.7 2.1 0.0 0.6 -1.4 0.5 -1.1 0.9 -0.2 0.9
Ever highly irritable/argumentative for 2 days 0.8 1.0 2.8 0.4 1.7 1.2 -0.8 -1.5 -0.1 -0.4 -0.6
Loud music exposure frequency 0.2 0.3 0.7 0.2 0.1 0.9 -0.7 0.4 -0.1 0.7 -0.1
Qualifications: O levels/GCSEs or equivalent 1.2 1.9 3.6 1.5 0.7 -0.1 0.9 1.3 -1.9 1.7 1.7
Mouth/teeth dental problems: Bleeding gums 1.5 1.9 10.1 -1.6 -0.8 0.6 -0.7 3.2 -0.0 -0.9 -0.3
Blood clot in the leg (DVT) 1.2 1.6 3.7 -1.9 1.0 1.0 -1.3 -1.7 -0.5 -1.5 0.1
Medication: Paracetamol 0.6 1.1 2.4 -1.0 1.5 1.4 0.7 0.3 -0.2 1.1 1.2
Headache pain in last month 2.2 3.8 9.5 -1.6 -0.5 0.2 -2.9 -1.6 -2.3 -3.1 -1.3
Medication for cholesterol, blood pressure or diabetes 1.2 2.0 7.3 -1.4 -0.9 -0.0 -1.6 -0.6 -2.7 -1.5 -0.6
Glaucoma (self-reported) 0.5 0.6 2.0 -0.8 -0.2 0.0 0.5 0.9 -0.7 0.6 1.4
Gout (self-reported) 1.2 1.6 4.7 1.5 -0.1 -2.2 0.8 -1.4 1.0 1.3 -0.9
Hypothyroidism/myxoedema (self-reported) 0.4 0.8 2.0 0.0 -0.5 -1.4 -0.9 -1.0 -0.0 -0.6 -1.4
Medication: Amlodipine 1.6 2.2 6.5 0.8 0.6 0.2 2.1 -0.6 2.5 1.6 1.7
Medication: Ventolin 100micrograms inhaler 0.4 0.6 3.1 1.0 0.3 0.4 0.2 -1.8 0.1 0.2 0.4
Birth weight 0.8 1.8 8.9 -0.7 -1.1 -1.2 -0.8 0.6 -3.0 -0.2 -1.0
Chronic bronchitis/emphysema (mother) 1.2 1.4 4.2 0.3 0.8 0.1 -2.0 -1.2 1.5 -0.8 -1.5
High blood pressure (siblings) 1.3 1.9 7.5 -0.6 0.6 0.0 1.7 0.1 2.7 1.4 1.4
Forced vital capacity (FVC), Best measure 0.9 3.2 11.1 -1.4 -1.1 -0.6 -2.4 0.0 -3.3 -1.5 -1.7
Body fat percentage 1.0 3.9 23.9 0.7 1.4 -0.6 1.5 0.5 4.9 1.1 -0.8
Leg fat percentage (right) 0.6 2.2 15.0 -0.4 0.4 -0.7 0.6 -0.4 3.9 0.0 -0.9
Arm fat-free mass (right) 0.4 2.1 4.4 1.6 1.1 -1.7 1.5 0.8 2.1 1.8 0.2
Exposure to tobacco smoke outside home 0.5 0.7 1.8 -0.5 1.4 0.9 -1.1 -0.1 0.5 -0.8 -0.6
Comparative body size at age 10 1.4 3.8 11.0 2.2 0.2 -3.3 2.5 0.8 1.8 2.1 0.6
Number of full brothers 1.1 1.4 3.0 1.7 1.7 0.8 0.8 -0.5 1.3 1.1 0.6
Worry too long after embarrassment 0.5 0.9 3.4 -1.5 0.7 1.8 0.5 -0.4 -0.3 0.8 -0.1
Seen a psychiatrist for nerves, anxiety, tension or depression 1.5 2.0 6.4 -1.2 0.2 0.1 -2.5 -1.4 -0.5 -1.8 -1.5
Wheeze or whistling in the chest in last year 0.7 1.3 5.1 -0.5 0.4 2.3 -0.6 0.1 2.0 -0.7 -0.6
Number of children fathered 0.2 0.2 0.8 0.4 -0.7 0.1 0.2 -0.4 0.9 0.3 0.4
Reason for reducing amount of alcohol drunk: Health precaution 0.7 0.8 2.4 -0.6 -0.2 -1.4 -0.6 -1.6 -0.8 -0.9 -0.3
Age at first live birth 0.8 1.4 5.0 0.4 0.6 -0.4 1.0 1.5 -2.2 1.1 1.1
Pulse wave peak to peak time 1.9 2.2 4.0 -1.1 -1.6 0.8 -1.4 2.0 -1.6 -1.1 -1.8
Health satisfaction 0.6 0.8 1.6 0.2 1.1 0.4 1.3 0.6 1.1 0.8 1.1
Shortness of breath walking on level ground 3.1 3.6 6.5 1.2 2.2 2.0 2.2 -0.8 2.5 1.8 1.8
Qualifications: College or University degree 1.1 3.4 8.1 2.2 -0.0 -0.8 2.4 1.2 -2.3 2.9 0.9
Eye problems/disorders: None of the above 0.8 1.0 1.7 1.3 1.0 -1.3 0.9 -0.1 1.3 0.9 0.3
Mouth/teeth dental problems: Loose teeth 3.1 3.7 8.4 2.4 1.2 0.1 2.6 1.4 1.1 2.9 2.0
Emphysema/chronic bronchitis 0.1 0.1 0.7 0.2 -0.3 -0.8 0.1 -0.2 -0.1 0.4 0.1
Medication for pain relief, constipation, heartburn 0.3 0.5 2.1 0.2 -1.4 0.1 -0.3 0.3 -1.1 0.3 0.5
Neck or shoulder pain in last month 1.7 2.4 4.6 1.3 2.2 0.1 1.7 0.3 1.3 2.1 1.9
Medication: Blood pressure 1.2 2.2 9.7 1.0 0.9 -0.7 1.5 0.3 3.1 1.5 0.8
Angina (self-reported) 1.0 1.3 5.6 0.7 -0.9 -0.4 0.3 0.8 2.4 -0.3 -1.7
Migraine (self-reported) 0.3 0.4 1.1 -0.7 -1.0 0.6 -0.7 0.3 -0.4 -0.4 -0.6
Medication: Ibuprofen 1.8 2.1 3.6 -1.1 -0.4 1.6 -1.8 0.9 -1.9 -1.5 -1.8
Medication: Allopurinol 1.0 1.3 5.1 1.4 0.7 -2.3 0.5 -0.4 0.8 1.4 0.1
Medication: Omeprazole 1.4 1.7 4.3 -0.5 0.5 -1.3 -1.6 -1.1 -0.8 -2.1 -1.6
Medication: Seretide 50 evohaler 0.6 0.7 3.9 1.0 -0.1 2.0 0.2 0.3 0.6 0.2 0.5
Mean time to correctly identify matches 1.1 2.1 4.9 -0.5 -1.5 -1.9 0.3 -2.2 -1.5 -1.3 -1.1
Heart disease (mother) 1.4 1.6 4.9 1.7 0.7 0.5 1.8 -0.1 0.5 2.2 1.1
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.3 0.4 0.9 0.8 0.3 0.8 -0.1 0.6 0.2 0.4 0.9
Whole body fat mass 1.1 4.5 22.7 1.3 1.5 -1.0 2.0 0.9 4.8 1.8 -0.3
Leg fat mass (right) 1.0 3.7 22.1 0.7 1.2 -1.0 1.6 0.3 4.7 1.3 -0.4
Arm predicted mass (right) 0.4 1.8 4.2 1.3 1.0 -1.7 1.2 0.7 2.0 1.7 0.1
Pulse rate, automated reading 0.4 1.2 3.5 -0.4 -0.4 1.9 0.9 -1.5 1.7 0.0 0.1
Alcohol intake frequency. 1.2 2.9 7.9 -1.6 0.9 -2.1 -2.8 -0.3 0.1 -2.4 -1.3
Comparative height size at age 10 0.6 3.3 10.1 3.2 0.5 -0.6 2.5 0.0 2.0 2.4 0.0
Number of full sisters 0.4 0.5 1.1 -0.8 -0.7 1.1 -0.7 0.5 -0.3 -0.7 -0.8
Suffer from ‘nerves’ 1.0 1.6 6.8 0.5 2.6 -0.0 0.5 -1.4 -1.2 1.2 0.8
Overall health rating 0.5 1.0 2.9 -0.2 0.7 0.9 0.7 1.4 1.7 0.9 0.5
Chest pain or discomfort 0.3 0.5 1.6 -1.0 0.6 0.4 -0.2 -0.7 1.3 0.2 0.0
Had major operations 0.3 0.3 1.6 0.6 0.3 1.3 -0.1 -0.1 0.1 -0.3 -0.6
Age at last live birth 0.4 0.5 2.5 -0.7 0.5 0.6 -0.2 0.3 -1.6 0.2 0.6
Family relationship satisfaction 0.7 0.8 2.5 1.1 1.6 1.3 -0.1 0.7 -0.7 -0.1 -0.1
Leg pain on walking 1.9 2.4 6.6 1.5 1.0 -0.1 2.6 0.1 1.9 1.7 1.6
Qualifications: NVQ or HND or HNC or equivalent 0.5 0.6 2.2 -0.1 -0.9 1.5 -0.3 -0.4 1.2 -0.3 -0.3
Commuting to job workplace: Car/motor vehicle 0.9 1.0 3.8 -0.8 -0.1 -0.4 -0.7 -0.3 -0.8 -1.9 -1.5
Illness, injury, bereavement, stress in last 2 years 0.7 0.8 2.6 -0.4 0.2 0.6 1.6 -0.8 0.3 0.5 1.6
Medication: Aspirin 1.6 2.1 5.2 1.9 1.5 -1.4 1.6 0.4 2.3 0.9 0.2
Supplements: Vitamin C 2.8 3.3 7.7 -1.1 -0.6 -0.5 -2.7 0.8 -1.4 -2.6 -2.8
Knee pain experienced in last month 0.3 0.5 2.0 0.7 1.0 1.4 0.1 -0.3 -0.1 0.2 0.4
Hypertension (Self-reported) 1.7 4.7 12.8 0.3 1.2 -0.7 3.3 0.1 3.6 2.2 2.7
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.4 0.5 1.8 0.1 0.4 0.4 -0.2 -0.3 0.2 -1.4 -1.3
Illnesses of father: Heart disease 1.2 1.6 4.0 -0.1 -0.8 2.0 1.8 -0.5 1.3 0.9 1.6
Illnesses of siblings: Diabetes 1.1 1.4 5.1 -0.7 1.4 -0.3 -1.3 -2.3 -0.1 -1.4 -0.1
Smoking status: Previous 0.7 1.1 2.3 0.7 0.6 -0.6 0.9 -1.5 0.7 1.4 1.4
Forced expiratory volume in 1-second (FEV1), predicted 1.2 2.4 6.6 -1.3 -1.9 0.6 -1.7 -0.6 -2.6 -1.3 -1.3
Whole body fat-free mass 0.4 2.4 5.0 1.6 1.2 -1.3 1.6 1.1 2.2 2.1 0.3
Leg fat-free mass (right) 0.8 4.1 12.5 1.7 1.7 -1.1 2.0 1.5 3.5 2.6 0.4
Arm fat percentage (left) 1.3 5.0 28.5 1.1 1.9 -0.2 1.9 0.8 5.3 1.6 -0.2
Average weekly red wine intake 0.5 0.7 2.9 -0.1 -0.2 -0.6 -0.2 1.7 -1.2 0.5 0.4
Handedness (chirality/laterality): Left-handed 2.1 2.5 5.3 -1.8 -1.0 1.3 -2.0 0.9 0.6 -2.3 -1.8
Mood swings 1.5 2.7 6.5 0.6 2.4 2.6 -0.7 -2.0 -1.8 0.2 1.0
Loneliness, isolation 0.8 1.1 3.8 0.3 1.9 0.3 -1.2 -1.0 0.1 -1.0 -1.3
Long-standing illness, disability or infirmity 0.9 1.4 5.0 1.1 0.9 0.4 1.4 0.9 2.2 0.9 -0.4
Ever had bowel cancer screening 3.3 3.9 8.3 1.4 1.5 0.4 2.9 0.5 1.8 2.5 2.8
Diabetes diagnosed by doctor 0.4 0.7 1.8 0.2 0.5 -0.8 1.3 1.2 0.9 0.7 -0.4
Ever had stillbirth, spontaneous miscarriage or termination 1.1 1.2 3.4 -1.0 -0.3 1.7 -0.9 0.9 -1.8 -0.4 -0.9
Friendships satisfaction 1.9 2.3 4.6 2.2 2.1 0.7 1.6 1.5 0.6 1.6 1.1
Qualifications: nursing, teaching 1.0 1.5 3.7 0.6 -0.8 -0.0 1.9 1.5 -1.9 1.1 -0.2
Commuting to job workplace: Walk 1.1 1.2 2.7 0.5 1.5 1.6 -0.5 0.8 1.1 1.0 1.3
Eye problems/disorders: Cataract 2.0 2.4 6.6 -2.6 -1.1 1.5 -1.2 0.5 -1.6 -2.1 -0.1
Mouth/teeth dental problems: Mouth ulcers 3.4 5.5 12.6 -3.6 -0.4 0.1 -3.5 -0.6 -2.1 -3.5 -1.3
Medication for cholesterol 0.5 0.8 2.0 1.4 -0.6 -0.8 -0.7 -0.9 -0.5 0.8 -1.1
Medication: Laxatives (e.g. Dulcolax, Senokot) 2.2 2.6 7.1 -0.6 -0.8 0.8 -0.9 -2.3 -0.9 -2.7 -2.2
Back pain experienced in last month 0.3 0.5 2.1 -1.4 0.1 1.1 0.2 0.1 0.3 -0.3 0.6
Mineral and other dietary supplements 0.7 0.9 2.3 -0.0 -0.1 0.6 -1.5 -1.4 -0.2 -1.5 -0.8
Breast cancer (self-reported) 0.4 0.5 1.2 1.1 0.2 -0.8 0.2 0.6 1.1 0.7 -0.0
Asthma (self-reported) 0.5 0.9 2.8 -0.3 -0.7 0.8 -1.1 -0.3 0.6 -1.3 -1.7
Osteoporosis (self-reported) 1.1 1.3 3.9 0.5 1.6 0.5 0.9 -0.9 1.0 1.0 2.0
Osteoarthritis (self-reported) 0.9 1.2 3.4 -0.8 -1.9 -1.5 1.0 0.8 -1.0 0.6 -0.0
Medication: Aspirin 1.0 1.3 4.0 1.3 1.4 -1.5 0.9 0.0 2.0 -0.0 -0.2
Medication: Gliclazide 0.8 0.9 2.6 0.7 -0.3 -1.6 0.8 1.5 0.3 0.5 -0.7
Illnesses of father: None of the above (group 1) 0.7 0.9 2.3 -1.4 -0.5 -0.5 -0.6 0.4 -1.5 -1.2 -0.3
Smoking status: Current 0.8 1.3 2.4 -0.7 0.0 1.5 -1.6 -1.3 0.2 -1.6 -1.0
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.3 0.6 2.2 1.5 -0.1 -0.2 0.1 -0.8 0.6 -0.1 -1.1
Whole body water mass 0.4 2.4 5.3 1.5 1.2 -1.1 1.6 1.2 2.3 2.2 0.4
Leg predicted mass (right) 0.8 4.0 12.5 1.7 1.6 -1.1 2.1 1.5 3.5 2.6 0.4
Arm fat mass (left) 1.3 5.4 27.3 1.5 2.1 -0.4 2.0 0.9 5.2 2.0 -0.0
Number of self-reported non-cancer illnesses 1.0 1.7 5.2 0.3 0.9 0.5 2.3 0.2 1.8 1.4 1.4
Average weekly champagne plus white wine intake 0.5 0.7 3.0 0.0 -1.0 0.1 1.1 1.7 -0.5 0.3 0.3
Miserableness 2.3 4.0 14.0 -0.4 2.6 3.7 -1.9 -2.3 0.2 -1.5 -0.3
Guilty feelings 1.0 1.5 4.2 -2.1 1.5 1.1 -0.9 -1.5 -0.7 -0.4 0.7
Wears glasses or contact lenses 1.4 1.6 3.4 -0.2 0.9 1.5 1.6 0.9 0.2 1.6 1.9
Ever taken oral contraceptive pill 3.8 4.2 8.9 -1.2 -2.2 0.4 -3.0 0.2 -2.0 -2.5 -2.8
Hearing aid user 0.9 1.1 3.5 0.1 -0.3 1.5 -1.4 0.7 0.5 -0.5 -1.9
Mother’s age at death 2.4 3.1 10.2 0.7 0.4 0.0 3.2 0.1 0.1 2.6 2.6
Financial situation satisfaction 0.4 0.4 1.3 0.7 0.1 1.1 0.4 0.9 0.4 0.7 0.3
Tinnitus: Yes, now most or all of the time 1.7 2.0 5.2 -2.3 0.0 1.1 -1.4 1.1 -1.9 -1.4 0.7
Commuting to job workplace: Public transport 0.5 0.6 3.1 0.2 0.2 -0.4 -0.4 1.8 1.1 0.5 0.2
Eye problems/disorders: Glaucoma 0.9 1.0 2.9 -0.9 -0.9 0.8 -0.6 1.0 -1.7 -0.2 1.2
Medication: Blood pressure 0.5 0.9 2.1 -0.3 0.4 -0.7 1.3 0.5 1.4 0.6 1.4
Pain type(s) experienced in last month: Hip pain 1.9 2.3 9.6 0.8 0.3 3.1 1.8 1.2 1.6 0.9 0.5
Supplements: Fish oil (including cod liver oil) 1.1 1.4 3.5 1.1 0.1 0.2 1.7 1.9 0.9 1.5 0.5
High cholesterol (Self-reported) 2.2 3.9 11.5 0.1 1.2 0.5 3.1 1.4 1.4 2.2 3.4
Medication: Bendroflumethiazide 1.9 2.9 8.2 1.0 1.7 0.3 2.1 0.1 1.0 2.3 2.9
Medication: Paracetamol 0.4 0.6 1.8 -0.9 1.3 0.3 0.1 0.3 -0.9 0.8 0.6
Medication: Lisinopril 0.6 0.7 1.8 1.4 -0.5 -0.4 0.9 0.2 1.0 0.9 0.9
Medication: Atorvastatin 0.1 0.2 0.5 -0.2 0.2 0.5 0.7 -0.5 -0.2 -0.1 0.5
Illnesses of father: High blood pressure 1.7 2.1 7.2 -0.4 1.6 2.7 0.1 -1.8 1.5 0.7 1.1
Alcohol drinker status: Never 0.8 1.0 2.4 1.0 1.6 -0.8 0.6 0.2 0.7 1.3 1.0
Ever smoked 0.6 1.1 5.7 0.1 1.2 -0.2 -0.4 -2.4 1.0 0.1 0.7
Basal metabolic rate 0.5 2.6 8.4 1.5 1.3 -1.1 1.4 1.2 2.9 2.0 0.1
Leg fat percentage (left) 0.7 2.7 18.4 -0.1 0.6 -0.9 1.1 -0.0 4.3 0.5 -0.7
Arm fat-free mass (left) 0.5 2.3 6.6 1.5 1.2 -1.2 1.5 1.0 2.6 1.8 0.2
Number of operations (self-reported) 0.7 1.0 3.2 0.6 -0.4 0.9 -0.5 -0.3 1.8 -1.1 -1.5
Average weekly beer plus cider intake 2.3 3.3 8.9 -0.3 0.7 0.3 -3.0 -2.5 0.1 -2.9 -1.5
Irritability 1.1 1.9 6.6 -0.4 2.6 2.1 -1.1 -0.7 -0.9 0.2 1.1
Risk taking 1.5 2.2 6.1 -0.6 -0.2 2.5 -2.3 0.2 0.2 -2.0 -1.3
Ever had prostate specific antigen (PSA) test 0.2 0.2 0.7 0.5 0.3 -0.8 0.3 0.3 0.5 0.3 0.2
Fractured/broken bones in last 5 years 1.6 2.1 6.8 -1.0 -1.3 -2.6 -1.3 -1.4 -1.4 -0.9 -0.7
Age started oral contraceptive pill 0.7 0.9 4.0 0.6 -0.6 0.0 1.2 -0.5 2.0 0.6 -0.3
Diastolic blood pressure, automated reading 1.0 3.0 16.3 -1.1 -0.2 -0.1 1.5 0.5 4.0 1.6 1.3
Ever depressed for a whole week 0.3 0.3 0.9 -0.1 0.0 0.8 0.2 0.9 -0.9 0.1 -0.3
Unable to work because of sickness or disability 1.2 1.5 5.2 -0.5 -0.7 -0.2 -0.7 -1.8 0.2 -1.5 -2.3
Commuting to job workplace: Cycle 1.0 1.2 6.9 -0.1 -0.2 -2.6 -1.0 -0.7 -0.8 -0.3 -0.4
Myopia 0.6 0.9 4.7 0.7 0.4 0.5 1.0 0.9 2.2 0.1 -0.1
Vascular/heart problems diagnosed by doctor 1.7 4.8 15.5 -0.6 -1.1 0.8 -3.1 -0.0 -3.9 -2.1 -2.4
Cholesterol lowering medication 0.6 0.8 3.1 -0.6 1.4 -0.0 0.6 -0.7 -0.4 -0.4 1.8
Medication: Omeprazole (e.g. Zanprol) 1.3 1.6 3.3 -0.2 0.9 -1.5 -1.6 -0.8 -0.6 -1.8 -1.6
Pain experienced in last month 0.1 0.1 0.4 -0.2 0.4 -0.6 -0.1 -0.3 -0.3 -0.2 0.4
Supplements: Calcium 0.8 0.8 2.4 1.2 1.6 -0.5 -0.6 0.8 -0.7 -0.4 -0.9
Basal cell carcinoma (self-reported) 1.6 1.9 6.4 -0.8 -2.1 -0.6 0.6 2.5 -1.7 0.0 0.0
Heart attack/myocardial infarction (self-reported) 0.1 0.1 0.2 0.1 0.4 -0.3 -0.1 -0.1 0.3 -0.4 -0.3
Deep venous thrombosis (DVT) (self-reported) 1.1 1.4 3.0 -1.7 1.2 0.9 -1.1 -1.6 -0.3 -1.4 0.2
Heart disease (siblings) 1.9 2.3 5.2 0.9 0.1 1.4 2.1 -0.4 2.3 1.6 1.8
Alcohol drinker status: Previous 1.4 1.5 3.8 -1.6 0.2 -0.7 -1.5 -0.6 1.3 -1.9 -1.2
Pack years of smoking 0.4 0.5 2.1 0.5 0.8 -0.1 -0.8 -0.5 1.4 -0.5 -0.4
Impedance of whole body 1.4 7.2 29.0 -1.9 -0.7 1.7 -3.2 -0.3 -5.4 -3.0 -1.4
Leg fat mass (left) 1.1 4.1 23.1 0.9 1.3 -1.2 1.8 0.4 4.8 1.6 -0.3
Arm predicted mass (left) 0.5 2.3 6.7 1.4 1.2 -1.3 1.5 1.0 2.6 1.8 0.1