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chr7:91,142,400-93,160,671

Best TWAS P=1.19e-14 · Best GWAS P=2.86e-15 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	CDK6	0.12	0.10	lasso	2	0.10	1.9e-12	-6.0	-6.0	1.7e-09	0.89	0.89	0.11	FALSE
2	GTEx	Adipose Visceral Omentum	GATAD1	0.12	0.08	lasso	5	0.06	7.5e-04	-5.9	5.5	3.1e-08	-0.51	0.78	0.11	FALSE
3	GTEx	Adrenal Gland	GATAD1	0.40	0.22	lasso	7	0.25	2.0e-09	-5.9	6.9	4.7e-12	-0.57	0.61	0.16	FALSE
4	GTEx	Artery Aorta	GATAD1	0.09	0.08	enet	4	0.07	7.4e-05	-5.9	5.7	9.5e-09	-0.49	0.48	0.12	FALSE
5	GTEx	Artery Coronary	GATAD1	0.12	0.15	lasso	3	0.12	8.0e-05	-5.7	6.0	2.6e-09	-0.54	0.16	0.34	FALSE
6	GTEx	Artery Tibial	GATAD1	0.14	0.04	enet	17	0.04	4.1e-04	-5.9	5.4	7.7e-08	-0.45	0.69	0.13	FALSE
7	GTEx	Brain Caudate basal ganglia	GATAD1	0.21	0.09	lasso	4	0.08	2.3e-03	-5.4	6.8	9.4e-12	-0.56	0.05	0.52	FALSE
8	GTEx	Cells Transformed fibroblasts	GATAD1	0.23	0.20	lasso	4	0.22	1.4e-16	-5.9	6.8	1.4e-11	-0.69	0.88	0.12	FALSE
9	GTEx	Colon Transverse	GATAD1	0.13	0.00	enet	16	0.05	3.0e-03	-5.9	7.3	3.4e-13	-0.52	0.15	0.38	TRUE
10	GTEx	Esophagus Muscularis	GATAD1	0.18	0.10	enet	33	0.13	1.6e-08	-5.9	5.6	2.2e-08	-0.38	0.97	0.01	FALSE
11	GTEx	Esophagus Muscularis	FAM133B	0.07	0.01	enet	2	0.01	1.2e-01	5.0	5.8	5.2e-09	-0.55	0.09	0.19	FALSE
12	GTEx	Lung	GATAD1	0.15	0.12	lasso	2	0.11	1.1e-08	-5.9	5.8	5.1e-09	-0.53	0.99	0.00	FALSE
13	GTEx	Muscle Skeletal	PEX1	0.06	0.03	lasso	5	0.02	2.7e-03	-5.5	-5.7	1.3e-08	0.42	0.34	0.44	FALSE
14	GTEx	Muscle Skeletal	GATAD1	0.05	0.00	enet	13	0.01	2.4e-02	-4.1	5.6	2.5e-08	-0.44	0.45	0.08	FALSE
15	GTEx	Nerve Tibial	GATAD1	0.30	0.19	lasso	5	0.23	1.8e-16	-5.9	5.2	2.3e-07	-0.44	1.00	0.00	FALSE
16	GTEx	Pancreas	GATAD1	0.12	0.13	lasso	2	0.14	2.0e-06	-5.9	5.2	1.7e-07	-0.49	0.09	0.73	FALSE
17	GTEx	Skin Not Sun Exposed Suprapubic	GATAD1	0.22	0.27	lasso	4	0.26	1.1e-14	-5.9	6.0	1.5e-09	-0.53	1.00	0.00	FALSE
18	GTEx	Skin Sun Exposed Lower leg	GATAD1	0.30	0.10	enet	14	0.16	7.0e-13	-5.9	5.5	4.0e-08	-0.44	1.00	0.00	FALSE
19	GTEx	Stomach	GATAD1	0.30	0.13	lasso	5	0.15	8.6e-08	-5.9	5.6	2.1e-08	-0.52	0.97	0.01	FALSE
20	GTEx	Testis	CDK6	0.10	0.10	lasso	3	0.09	8.0e-05	-7.9	7.7	1.2e-14	-0.96	0.00	0.99	TRUE
21	GTEx	Thyroid	GATAD1	0.18	0.06	lasso	4	0.06	3.3e-05	-5.9	5.5	4.4e-08	-0.48	0.97	0.01	FALSE
22	ROSMAP	Brain Pre-frontal Cortex	KRIT1	0.04	0.03	bslmm	311	0.01	9.0e-03	-5.2	-6.5	6.0e-11	0.51	0.73	0.07	FALSE
23	ROSMAP	Brain Pre-frontal Cortex	GATAD1	0.17	0.15	lasso	4	0.16	6.0e-20	-6.1	6.0	2.2e-09	-0.51	1.00	0.00	FALSE
24	YFS	Blood	GATAD1	0.01	0.01	blup	297	0.01	5.1e-04	-5.9	5.7	1.2e-08	-0.53	0.74	0.09	FALSE
25	The Cancer Genome Atlas	Breast Invasive Carcinoma	GATAD1	0.06	0.04	lasso	6	0.04	2.2e-09	-6.1	6.2	5.5e-10	-0.40	0.00	1.00	FALSE
26	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	GATAD1	0.04	0.04	lasso	2	0.03	2.8e-04	-6.1	6.0	1.9e-09	-0.47	0.00	0.99	FALSE
27	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	C7orf64	0.06	0.02	blup	36	0.02	6.0e-02	-5.6	-5.2	1.6e-07	0.42	0.02	0.53	FALSE