Best TWAS P=7.77e-11 · Best GWAS P=9.47e-13 conditioned to 0.000104
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Esophagus Gastroesophageal Junction | MKLN1-AS2 | 0.20 | 0.05 | lasso | 6 | 0.02 | 7.8e-02 | -4.3 | -6.5 | 7.8e-11 | 0.64 | 0.14 | 0.44 | TRUE |
| 2 | GTEx | Heart Atrial Appendage | MKLN1-AS2 | 0.15 | 0.06 | lasso | 3 | 0.08 | 2.2e-04 | -3.9 | -5.4 | 8.5e-08 | 0.47 | 0.41 | 0.15 | FALSE |
| 3 | GTEx | Nerve Tibial | MKLN1-AS2 | 0.20 | 0.16 | lasso | 7 | 0.16 | 1.3e-11 | -4.5 | -5.3 | 9.7e-08 | 0.66 | 0.95 | 0.05 | FALSE |