TWAS hub - MKLN1-AS2

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.120	0.0500	7.6e-03	0.096	NA	0.075	NA	0.095	3.1e-08	NA	1.0e-06	NA	3.4e-08
2	GTEx	Artery Aorta	0.138	0.0510	3.2e-03	0.072	NA	0.048	NA	0.047	8.3e-05	NA	1.2e-03	NA	1.3e-03
3	GTEx	Artery Coronary	0.392	0.1100	5.8e-04	0.014	NA	-0.007	NA	-0.008	1.1e-01	NA	6.4e-01	NA	8.3e-01
4	GTEx	Artery Tibial	0.137	0.0487	1.4e-03	0.048	NA	0.043	NA	0.027	1.1e-04	NA	2.4e-04	NA	3.3e-03
5	GTEx	Cells Transformed fibroblasts	0.147	0.0460	1.8e-03	0.000	NA	0.005	NA	0.006	3.1e-01	NA	1.2e-01	NA	1.1e-01
6	GTEx	Esophagus Gastroesophageal Junction	0.202	0.0750	2.5e-03	0.052	NA	0.016	NA	0.017	6.0e-03	NA	8.4e-02	NA	7.8e-02
7	GTEx	Heart Atrial Appendage	0.152	0.0540	1.9e-03	0.057	NA	0.062	NA	0.078	1.4e-03	NA	9.4e-04	NA	2.2e-04
8	GTEx	Lung	0.155	0.0481	1.1e-03	0.017	NA	0.014	NA	0.028	1.8e-02	NA	2.7e-02	NA	3.0e-03
9	GTEx	Nerve Tibial	0.200	0.0504	5.5e-07	0.165	NA	0.138	NA	0.163	9.4e-12	NA	5.3e-10	NA	1.3e-11
10	GTEx	Ovary	0.368	0.1160	8.5e-03	0.213	NA	0.067	NA	0.153	5.8e-06	NA	1.0e-02	NA	1.4e-04
11	GTEx	Pituitary	0.381	0.1320	6.3e-03	-0.003	NA	-0.001	NA	-0.004	4.0e-01	NA	3.4e-01	NA	4.3e-01
12	GTEx	Thyroid	0.280	0.0510	1.2e-11	0.223	NA	0.220	NA	0.246	5.2e-17	NA	8.5e-17	NA	8.6e-19

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12
Relative age of first facial hair	27.5	56.6	102.0	-7.1	-7.2	-9.2	-7.8	-5.9	-9.4	-6.1	-7.1	-10.1	-3.3	-5.0	-9.2
Hair/balding pattern: Pattern 4	11.6	28.2	48.3	5.6	5.2	5.9	5.8	4.4	6.7	3.7	5.6	7.0	2.1	1.7	6.8
Systolic Blood Pressure	8.0	40.1	81.5	-5.9	-6.9	-2.8	-6.2	-4.3	-9.0	-7.4	-6.4	-7.3	-4.9	-5.5	-6.9
Pulse rate, automated reading	7.9	25.6	46.5	4.8	4.8	6.0	5.1	4.8	6.0	3.5	4.5	6.7	2.5	3.3	6.8
Systolic blood pressure, automated reading	7.1	20.7	42.3	-4.2	-4.6	-1.9	-4.6	-3.4	-6.5	-5.4	-4.5	-5.3	-3.5	-4.4	-4.8
Relative age voice broke	6.8	10.4	20.9	-3.6	-3.1	-3.7	-2.6	-3.2	-3.7	-2.4	-3.3	-4.6	-1.5	-1.5	-4.0
Pulse rate	5.5	9.2	19.7	3.2	2.7	3.0	2.6	3.4	3.0	1.6	3.2	4.3	1.2	1.8	4.4
Medication: Aspirin	4.5	5.8	10.8	2.9	2.9	1.7	2.6	3.3	1.9	1.7	2.8	2.7	1.5	1.2	2.8
Number of treatments/medications taken	4.2	7.6	10.2	3.1	3.2	2.5	2.8	2.5	3.0	2.8	2.6	3.2	1.4	2.5	3.2
Medication: Aspirin	4.2	5.5	10.0	2.7	2.8	1.8	2.5	3.2	1.8	1.8	2.6	2.5	1.8	1.4	2.6
Hearing difficulty/problems: Yes	3.6	5.4	9.2	-2.4	-2.7	-1.5	-2.1	-2.1	-3.0	-2.5	-2.4	-2.5	-2.1	-1.5	-2.6
Medication: Paracetamol	3.5	5.9	9.4	3.1	3.0	1.4	1.8	2.1	2.9	2.4	2.8	2.9	0.4	1.7	2.9
Ever used hormone-replacement therapy (HRT)	3.4	4.3	7.8	2.5	2.1	1.1	1.8	1.8	2.4	1.8	2.4	2.8	0.7	1.9	2.6
Medication for pain relief, constipation, heartburn	3.4	5.7	9.5	-3.1	-2.8	-1.6	-2.4	-2.9	-2.2	-1.9	-2.5	-2.8	-1.4	-1.1	-3.0
Taking other prescription medications	3.1	4.8	7.9	2.7	2.4	0.6	2.3	2.8	2.1	2.0	2.4	2.7	1.5	0.7	2.6
Serious illness, injury or assault to yourself	3.0	3.6	7.3	2.1	2.1	0.4	1.9	2.7	1.4	2.0	2.1	2.1	1.5	1.2	2.2
Happiness	3.0	3.6	7.4	2.6	1.6	0.8	1.8	2.4	1.2	1.1	2.7	2.6	0.4	0.3	2.5
Diastolic blood pressure, automated reading	3.0	9.3	24.9	-2.8	-2.7	-1.2	-2.8	-1.6	-5.0	-3.8	-3.1	-3.8	-2.8	-2.2	-3.0
Medication: Blood pressure	2.9	5.4	15.6	-2.5	-2.6	-0.6	-1.3	-0.8	-4.0	-2.6	-3.0	-2.7	-1.7	-1.8	-2.3
Medication: Ibuprofen (e.g. Nurofen)	2.8	3.6	5.5	2.2	2.2	2.0	2.1	2.1	1.5	1.5	2.0	2.0	1.1	1.1	2.4
Past tobacco smoking	2.5	4.6	8.1	-2.5	-2.6	-1.2	-2.2	-1.8	-2.5	-1.9	-2.3	-2.6	-0.6	-1.4	-2.8
Pulse wave Arterial Stiffness index	2.4	2.8	6.6	2.0	1.7	1.5	1.0	2.6	1.3	1.2	1.8	2.2	0.3	0.6	2.1
Medication: Ibuprofen	2.4	2.9	4.8	2.0	1.8	1.5	2.1	2.1	1.3	1.1	1.8	2.0	0.8	0.7	2.2
Ever taken oral contraceptive pill	2.3	2.5	6.3	-1.6	-1.9	-1.5	-1.8	-2.5	-0.5	-1.7	-1.3	-1.6	-1.1	-0.2	-1.8
Major Depression (MDD)	2.2	2.7	6.0	2.5	1.7	-1.3	1.5	1.7	1.5	1.4	1.9	2.0	0.2	0.6	2.1
Pulse wave peak to peak time	2.2	2.6	6.2	-1.8	-1.8	-1.3	-1.1	-2.5	-1.4	-1.3	-1.7	-2.0	-0.3	-0.8	-2.0
Medication: Paracetamol	2.2	3.3	6.0	2.2	2.1	1.6	1.2	1.4	2.2	1.6	1.9	2.5	-0.1	1.5	2.4
Basal cell carcinoma (self-reported)	2.2	2.7	5.8	1.9	1.9	0.9	1.7	1.1	1.9	1.6	1.3	1.9	0.2	2.4	1.6
Vitamin and mineral supplements	2.0	2.7	4.4	-1.2	-2.0	-1.5	-2.1	-1.6	-1.5	-2.1	-1.5	-1.6	-1.2	-1.2	-1.7
Stomach or abdominal pain in last month	2.0	2.6	4.8	1.8	2.1	0.3	1.9	2.2	1.3	1.8	1.2	1.8	1.2	0.8	1.8
Knee pain experienced in last month	2.0	3.1	7.4	1.6	2.1	0.1	1.9	2.7	1.5	2.2	1.8	1.5	2.0	0.3	1.4
Back pain experienced in last month	2.0	2.9	4.5	2.1	2.0	1.0	1.4	2.1	1.8	1.7	1.9	2.0	1.0	0.4	1.8
Mineral and other dietary supplements	2.0	2.7	5.9	-1.6	-1.8	-1.3	-2.4	-1.7	-1.4	-1.0	-1.6	-2.1	-0.7	-0.3	-2.2
Medication: Co-codamol	1.9	2.2	3.4	1.8	1.6	0.4	1.7	1.8	1.3	1.4	1.9	1.4	1.8	0.5	1.3
Ever unenthusiastic/disinterested for a whole week	1.9	2.3	5.3	1.8	1.2	1.6	1.7	2.3	0.6	0.3	1.6	1.9	1.4	0.1	2.0
Impedance of arm (right)	1.9	8.8	15.8	-2.7	-3.7	-2.2	-2.6	-1.7	-4.0	-3.6	-2.7	-3.0	-1.7	-3.2	-3.3
Number of children fathered	1.9	2.1	3.5	1.4	1.6	1.9	1.5	1.1	1.4	1.7	1.5	1.2	1.3	1.6	1.3
Ever smoked	1.9	3.3	5.4	2.1	2.3	0.6	2.0	1.8	1.9	1.5	2.1	2.1	0.5	1.6	2.3
Heart disease (siblings)	1.9	2.3	4.1	1.5	1.6	1.3	1.7	1.4	1.1	1.7	1.3	1.6	2.0	0.8	1.9
HbA1C	1.8	2.0	4.8	-1.6	-1.7	-0.7	-2.2	-2.1	-0.8	-1.7	-1.2	-1.4	-0.5	-0.3	-1.3
Cardiovascular Disease	1.8	5.9	18.3	-2.0	-1.8	-1.6	-2.1	-1.1	-4.3	-2.7	-2.8	-3.1	-2.2	-1.2	-2.6
Frequency of tenseness / restlessness in last 2 weeks	1.8	2.7	6.1	-1.5	-1.8	-0.4	-2.2	-0.7	-2.5	-1.9	-1.4	-2.1	0.2	-1.5	-2.0
Smoking Status	1.7	4.0	6.4	1.9	2.5	2.5	1.9	2.0	2.1	2.1	1.3	1.8	1.0	2.2	2.3
High blood pressure	1.7	4.6	14.3	-1.9	-1.6	-1.5	-2.1	-0.7	-3.8	-2.2	-2.4	-3.0	-0.8	-1.3	-2.3
Hypertension (Self-reported)	1.7	4.7	14.2	-1.9	-1.7	-1.6	-2.1	-0.7	-3.8	-2.3	-2.4	-3.0	-0.7	-1.4	-2.3
Commuting to job workplace: Walk	1.7	1.8	4.6	-1.2	-1.1	-1.5	-1.6	-0.9	-1.3	-1.1	-1.1	-1.2	-0.1	-2.1	-1.8
Vascular/heart problems diagnosed by doctor	1.7	4.7	13.2	2.2	1.9	1.1	2.0	0.9	3.6	2.2	2.5	3.1	0.4	1.3	2.5
Prostate Cancer	1.6	2.3	5.3	-1.5	-1.4	-1.5	-0.9	0.0	-2.2	-1.2	-1.6	-1.5	1.0	-2.3	-1.7
Neuroticism (2016)	1.6	2.3	4.3	2.1	1.6	-0.0	0.8	1.9	1.2	1.2	1.6	1.8	1.1	1.8	1.7
Seen doctor (GP) for nerves, anxiety, tension or depression	1.6	2.5	6.1	1.4	1.4	1.9	1.4	0.3	2.5	1.7	1.3	1.6	1.0	1.7	1.7
Smoking status: Previous	1.6	2.4	4.5	1.8	1.8	1.1	1.4	1.0	1.9	1.3	1.7	1.9	0.1	1.2	2.1
Alzheimer’s Disease (in father)	1.5	1.6	3.1	-1.3	-1.3	0.7	-1.1	-0.7	-1.8	-1.8	-1.4	-1.5	0.2	-1.0	-1.4
Mouth/teeth dental problems	1.5	2.3	5.8	-1.6	-1.8	0.1	-2.1	-2.4	-0.6	-1.0	-1.2	-1.7	-1.2	-0.9	-1.8
Pain all over the body in last month	1.5	1.6	4.0	-1.0	-1.7	2.0	-0.2	-1.8	-0.4	-1.6	-1.1	-0.6	-0.9	-1.5	-0.4
Length of working week for main job	1.5	1.7	4.7	1.0	1.2	1.9	1.1	0.4	2.2	1.3	0.9	1.5	0.4	1.2	1.4
Hair/balding pattern: Pattern 3	1.4	2.0	4.9	1.0	1.3	1.9	2.2	0.8	1.6	1.8	0.9	1.6	0.6	0.7	1.6
Blood clot in the leg (DVT)	1.4	1.8	6.0	1.5	1.4	1.2	0.6	0.8	1.6	0.3	1.4	1.3	1.1	2.5	1.1
Exposure to tobacco smoke outside home	1.4	1.9	5.4	-1.1	-1.2	-1.8	-0.4	-0.3	-2.3	-1.4	-0.8	-1.4	-0.5	-2.3	-1.3
Average weekly champagne plus white wine intake	1.4	1.9	4.0	-1.4	-1.6	-1.1	-1.0	-0.5	-2.0	-1.2	-1.4	-1.6	-0.3	-1.9	-1.5
Impedance of arm (left)	1.3	5.8	10.4	-2.4	-3.1	-1.7	-2.1	-1.4	-3.2	-2.6	-2.3	-2.5	-1.1	-2.6	-2.9
Arm fat-free mass (right)	1.3	6.8	11.0	2.7	2.8	2.9	2.1	1.6	2.9	2.2	2.6	2.8	1.5	3.2	3.3
Age at first live birth	1.3	2.3	7.5	-1.1	-2.1	-0.3	-2.7	-1.7	-1.1	-1.9	-0.6	-1.1	-1.7	-0.1	-1.3
Emphysema/chronic bronchitis	1.3	1.5	5.5	0.9	0.8	2.3	1.0	-0.0	1.8	0.6	0.8	1.1	0.8	1.7	1.0
Arm predicted mass (right)	1.3	6.8	11.6	2.8	2.9	2.4	2.1	1.7	2.9	2.3	2.7	2.9	1.4	3.1	3.4
Supplements: Fish oil (including cod liver oil)	1.3	1.7	3.5	1.2	1.4	1.3	1.8	1.6	0.9	0.3	1.4	1.7	0.7	-0.7	1.9
Medication: Atorvastatin	1.3	1.7	6.2	1.3	1.3	0.1	2.5	1.4	1.0	1.6	0.7	1.1	0.1	1.4	1.0
Illnesses of father: High blood pressure	1.3	1.6	2.6	-0.8	-1.1	-1.6	-1.5	-1.6	-1.2	-1.0	-1.1	-1.2	-1.6	-1.0	-0.9
Commuting to job workplace: Cycle	1.3	1.6	6.4	-1.1	-1.2	-0.5	-0.3	-0.8	-1.5	-1.4	-1.3	-1.1	-0.9	-2.5	-1.1
Average weekly spirits intake	1.2	1.5	2.9	0.9	1.2	0.7	1.6	0.5	1.5	1.7	1.4	1.1	0.7	1.4	1.1
Sensitivity / hurt feelings	1.2	2.1	3.6	-1.6	-1.5	-1.2	-1.2	-1.1	-1.9	-0.7	-1.9	-1.5	-0.8	-1.5	-1.7
Supplements: Zinc	1.2	1.3	8.9	0.2	0.8	3.0	0.0	0.7	0.6	1.1	0.1	0.0	1.5	1.5	0.3
Alcohol usually taken with meals	1.2	1.9	4.0	-1.7	-1.5	-1.0	-1.3	-0.4	-2.0	-0.5	-1.4	-1.8	0.1	-1.6	-1.6
Trunk fat-free mass	1.2	7.0	11.5	2.9	2.8	2.9	2.1	1.6	3.0	2.0	2.8	2.9	1.2	3.1	3.4
Frequency of tiredness / lethargy in last 2 weeks	1.2	2.0	5.0	1.2	1.4	1.0	0.8	2.0	0.3	1.5	1.3	0.9	2.2	1.7	1.2
Trunk predicted mass	1.2	7.1	11.6	2.9	2.8	2.9	2.2	1.6	3.1	2.1	2.8	3.0	1.3	3.1	3.4
Comparative body size at age 10	1.2	3.2	5.8	1.7	2.4	0.9	2.3	1.8	1.6	2.1	1.7	1.9	0.7	1.2	2.1
Average weekly red wine intake	1.2	1.8	4.5	-1.6	-1.8	1.3	-0.8	-0.4	-2.1	-1.2	-1.5	-1.2	0.4	-1.7	-1.0
Pain experienced in last month	1.2	2.0	3.1	-1.5	-1.6	-1.6	-1.0	-1.8	-1.5	-1.6	-1.1	-1.7	-1.1	0.3	-1.8
Alcohol drinker status: Previous	1.2	1.3	2.2	1.2	1.4	0.2	1.2	1.4	1.1	0.9	1.1	1.2	1.0	1.0	1.5
Primary Biliary Cirrhosis	1.1	1.6	4.5	-1.4	-1.4	0.2	-1.8	-2.1	-0.4	-0.9	-0.9	-1.2	-1.3	0.5	-1.5
Current tobacco smoking	1.1	1.8	3.9	0.7	1.6	1.5	1.1	1.5	1.3	1.7	0.4	0.8	1.5	2.0	0.9
Medication: Ramipril	1.1	1.4	4.1	1.1	1.1	1.2	1.7	2.0	-0.0	0.9	0.8	1.0	1.2	0.4	1.4
Qualifications: O levels/GCSEs or equivalent	1.1	1.7	3.6	-1.7	-1.7	-1.0	-0.8	-1.9	-0.7	-0.7	-1.4	-1.6	-0.6	0.7	-1.7
Birth weight	1.1	2.3	5.0	1.2	1.4	0.1	2.2	1.3	1.6	2.2	1.4	1.6	1.6	1.4	1.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.1	1.3	2.4	-1.1	-1.5	-0.0	-1.5	-1.3	-1.0	-1.3	-0.9	-1.2	-1.1	0.1	-1.3
Age at last live birth	1.1	1.6	5.7	-0.7	-1.5	-1.7	-2.4	-1.1	-0.9	-1.2	-0.5	-0.9	-1.5	-0.2	-1.1
Smoking status: Current	1.1	1.7	3.8	0.7	1.5	1.5	1.1	1.6	1.2	1.7	0.2	0.8	1.5	2.0	0.9
Whole body water mass	1.1	6.2	10.2	2.7	2.7	2.6	1.8	1.6	2.8	1.9	2.6	2.7	1.6	3.0	3.2
Deep venous thrombosis (DVT) (self-reported)	1.1	1.4	6.6	1.3	1.2	1.1	0.4	0.4	1.5	0.3	1.1	1.1	0.6	2.6	0.9
Impedance of whole body	1.1	5.5	9.6	-2.3	-3.1	-1.6	-1.9	-1.4	-3.1	-2.7	-2.1	-2.3	-1.8	-2.5	-2.7
Medication: Metformin	1.0	1.5	3.9	1.3	1.3	-1.2	1.4	2.0	0.6	1.1	1.1	0.9	1.0	1.1	1.1
Multivitamins +/- minerals	1.0	1.3	3.5	0.8	1.6	0.6	1.4	0.9	0.9	1.9	1.0	0.9	0.5	1.0	1.1
Hearing difficulty/problems with background noise	1.0	1.6	5.6	-0.6	-0.9	-1.2	-0.9	0.6	-2.4	-1.8	-0.8	-1.0	-0.2	-1.9	-1.0
Medication: Cholesterol lowering	1.0	1.6	2.5	1.6	1.2	1.5	1.4	1.0	1.1	1.3	1.3	1.3	0.5	1.4	1.4
Depression (self-reported)	1.0	1.3	3.5	0.9	1.2	1.4	0.0	0.7	1.2	1.4	0.7	0.8	1.9	1.1	1.1
Health satisfaction	1.0	1.3	4.1	1.3	0.7	0.7	1.2	2.0	-0.3	-0.3	1.4	1.4	0.2	-0.1	1.7
Commuting to job workplace: Car/motor vehicle	1.0	1.1	3.2	0.8	0.9	-0.5	1.0	-0.6	1.8	0.6	0.6	1.0	-1.6	1.5	1.1
Whole body fat-free mass	1.0	5.5	9.4	2.6	2.5	2.5	1.7	1.4	2.6	1.8	2.5	2.5	1.4	2.8	3.1
Ever had bowel cancer screening	1.0	1.1	5.7	0.9	0.5	0.1	1.1	1.3	0.1	-0.2	0.8	1.3	-0.6	-2.4	1.3
Supplements: Calcium	1.0	1.1	2.0	1.2	1.2	-0.7	0.1	1.2	0.9	1.0	1.4	1.1	0.7	1.0	1.2
Ever had hysterectomy (womb removed)	0.9	1.0	2.6	1.6	1.3	-0.8	-0.3	1.3	0.1	-1.2	1.2	1.0	0.3	-0.1	1.0
Bilateral oophorectomy (both ovaries removed)	0.9	1.1	4.5	-0.3	-0.6	-0.6	-1.2	0.4	-1.8	-2.1	-0.9	-0.7	-0.5	-0.9	-0.2
Had other major operations	0.9	1.1	5.1	-0.1	-0.8	0.3	-2.2	-0.9	-0.3	-1.4	-0.5	-0.4	-1.2	-1.6	-0.1
Chronic bronchitis/emphysema (mother)	0.9	1.0	4.6	0.2	0.0	0.7	-0.1	1.6	-1.1	0.5	-0.1	-0.1	2.1	-1.7	-0.1
Medication for cholesterol	0.9	1.3	2.8	1.1	1.2	-0.6	1.1	0.8	1.7	1.4	1.3	1.3	1.4	-0.5	0.8
Breast cancer (self-reported)	0.9	1.0	2.1	-0.8	-0.7	-1.1	-0.6	-0.9	-1.3	-1.3	-0.6	-0.8	-1.4	-1.2	-0.9
Guilty feelings	0.9	1.3	4.8	1.0	0.9	0.2	1.2	1.7	0.4	1.2	1.0	1.2	2.2	-0.2	0.8
Average weekly beer plus cider intake	0.9	1.2	4.2	-0.1	0.9	1.8	2.1	-0.1	1.6	1.1	0.0	1.0	1.1	0.7	0.3
Alzheimer’s Disease (including proxy)	0.8	1.2	5.2	-0.7	-1.1	-0.0	-0.8	0.0	-1.5	-1.1	-0.8	-0.9	1.0	-2.3	-1.0
Bipolar Disorder (2011)	0.8	0.8	1.6	-0.9	-1.2	0.3	0.4	-1.1	-0.7	-1.1	-1.3	-0.7	-0.8	-0.9	-0.9
Blood White Count	0.8	5.7	12.2	2.4	2.8	3.5	0.5	2.5	1.5	2.6	2.2	2.1	2.5	2.6	2.3
Diabetes (mother)	0.8	1.1	3.6	1.0	1.1	-0.8	1.3	0.8	1.1	0.6	0.8	0.9	0.2	1.9	1.0
Frequency of unenthusiasm / disinterest in last 2 weeks	0.8	1.0	3.6	-0.7	-1.3	-0.7	-1.5	0.0	-1.6	-1.9	-0.5	-0.4	-0.2	-0.7	-0.4
Nervous feelings	0.8	1.5	4.3	-1.3	-2.1	-0.4	-0.6	-0.6	-1.7	-1.7	-1.1	-0.6	-1.1	-1.6	-0.7
Hayfever/allergic rhinitis (self-reported)	0.8	1.1	4.7	-0.3	-1.0	-1.0	-1.3	-1.6	-0.1	-2.2	-0.2	-0.5	-1.0	-0.9	-0.7
Alcohol intake versus 10 years previously	0.8	1.2	3.8	-0.9	-0.8	-0.3	-1.7	-2.0	-0.3	-1.3	-1.0	-0.8	-1.4	-0.4	-0.7
High blood pressure (siblings)	0.8	1.2	5.6	-0.6	-1.0	-0.2	-0.7	-0.4	-1.3	-1.7	-1.0	-1.0	-0.2	-2.4	-0.7
Osteoarthritis (self-reported)	0.8	1.0	2.6	1.3	1.3	0.6	0.5	1.6	0.4	0.2	1.3	0.9	1.0	-0.4	1.3
Commuting to job workplace: Public transport	0.8	0.9	3.1	-0.3	-0.6	0.4	-1.1	0.8	-1.4	-0.9	-0.2	-0.5	1.4	-1.8	-0.5
Medication: Bendroflumethiazide	0.8	1.2	2.1	-0.9	-1.0	-0.7	-1.4	-0.5	-1.4	-1.5	-1.2	-1.1	-0.9	-0.9	-0.9
Arm fat-free mass (left)	0.8	4.3	7.7	2.2	2.2	2.5	1.5	1.2	2.2	1.4	2.1	2.1	0.9	2.8	2.7
Fractured/broken bones in last 5 years	0.8	1.0	3.5	0.6	0.9	-1.4	-0.0	1.0	-0.1	0.4	1.0	0.0	1.8	1.9	0.2
Age started oral contraceptive pill	0.8	1.0	4.8	0.4	-0.5	-0.0	-1.5	0.4	-0.7	-1.9	0.5	0.3	-0.2	-2.2	0.5
Arm predicted mass (left)	0.8	4.3	7.4	2.3	2.3	2.5	1.4	1.2	2.2	1.5	2.2	2.1	0.8	2.7	2.7
Verbal and Numeric Reasoning (VNR)	0.7	1.6	3.1	1.1	1.2	1.5	1.1	1.2	1.3	0.9	1.4	1.0	1.8	1.0	1.5
Body Mass Index (BMI) (2010)	0.7	1.0	2.1	1.4	0.9	0.2	0.6	0.6	1.2	0.6	1.4	1.3	0.4	0.7	1.4
Height	0.7	13.8	28.3	4.2	3.1	4.3	3.1	2.5	4.6	1.6	4.3	5.0	1.6	2.3	5.3
Angina	0.7	0.9	1.8	1.3	0.6	1.3	0.8	0.6	1.2	0.3	1.1	1.0	0.2	1.0	1.3
Diabetes (father)	0.7	0.8	1.8	0.4	1.0	-0.6	1.2	1.0	0.3	1.2	0.6	0.4	1.3	1.3	0.8
Chronic bronchitis/emphysema (father)	0.7	0.9	2.7	0.7	0.7	1.6	1.4	0.7	0.8	0.0	0.5	1.0	0.4	1.2	0.9
Diabetes (self-reported)	0.7	1.1	4.0	0.8	1.2	-0.0	2.0	1.5	0.4	1.4	0.7	0.8	0.2	0.2	0.9
Mouth/teeth dental problems: Dentures	0.7	1.2	3.2	0.4	1.1	1.8	1.6	0.8	0.9	1.0	0.0	1.0	0.7	1.3	1.0
Ever highly irritable/argumentative for 2 days	0.7	0.8	2.0	-0.8	-1.2	-0.4	-0.3	-0.4	-1.4	-1.1	-1.1	-1.1	-0.0	-0.7	-1.2
Medication: Amlodipine	0.7	1.0	2.6	-1.2	-0.5	0.1	-0.6	-0.6	-1.6	-0.9	-1.5	-1.5	-0.6	-0.7	-1.0
Supplements: Vitamin C	0.7	0.8	2.0	0.7	1.3	1.3	0.9	0.4	0.9	1.4	0.6	0.7	0.8	0.5	0.6
Basal metabolic rate	0.7	4.0	8.0	2.1	2.1	2.4	1.3	1.1	2.1	1.4	2.0	2.0	1.1	2.8	2.5
Irritability	0.7	1.3	2.6	-1.3	-1.2	1.2	-0.8	-0.6	-1.3	-1.1	-1.6	-1.0	0.6	-1.1	-1.1
Ever depressed for a whole week	0.7	0.9	1.9	-1.2	-1.1	-0.3	-0.3	-0.6	-1.1	-0.9	-1.4	-0.7	-0.5	-1.3	-0.9
Myopia	0.7	1.0	3.5	-1.1	-1.4	0.1	-1.1	-1.9	-0.6	-0.9	-0.9	-0.7	-0.7	0.1	-0.6
Schizophrenia vs Biploar Disorder	0.6	0.8	2.5	0.8	0.6	1.0	0.5	0.9	0.1	0.2	0.9	1.0	-0.7	1.6	1.2
Worry (Nagel 2018)	0.6	1.3	4.3	-1.4	-2.1	0.0	-0.4	-0.8	-1.1	-1.4	-1.4	-0.6	0.3	-1.5	-1.1
Triglycerides	0.6	1.0	1.9	-1.2	-1.2	0.6	-1.4	-1.0	-1.1	-0.9	-1.1	-1.2	0.2	-0.3	-1.3
Ulcerative Colitis	0.6	0.9	2.3	-1.0	-0.7	1.2	-0.6	-0.9	-0.8	-0.6	-1.0	-1.1	-0.2	-1.5	-0.9
Blood Eosinophil Count	0.6	4.8	10.4	3.2	2.8	0.4	0.8	1.6	2.5	1.7	3.0	2.8	0.5	1.7	2.7
Hand grip strength (left)	0.6	1.5	7.4	0.5	1.3	1.1	0.4	0.3	1.4	1.7	0.7	0.4	1.0	2.7	0.7
Qualifications: CSEs or equivalent	0.6	0.9	2.1	-0.7	-0.7	-1.2	-1.4	-1.0	-0.7	-1.4	-0.7	-0.9	-0.7	0.2	-0.7
Fluid intelligence score	0.6	1.2	3.8	0.6	0.8	2.0	1.2	0.4	1.4	0.8	0.9	0.8	0.9	1.4	1.2
Noisy workplace	0.6	0.7	4.8	0.2	0.0	2.2	0.7	-0.2	0.9	-0.4	0.4	0.9	-0.8	0.8	0.7
Qualifications: A levels/AS levels or equivalent	0.6	1.4	4.9	-0.8	-1.6	-0.8	-2.2	-0.8	-1.1	-1.5	-0.5	-1.2	-0.5	-0.3	-1.2
Exposure to tobacco smoke at home	0.6	0.7	2.9	0.5	0.9	0.5	1.7	0.8	0.5	0.9	0.4	0.7	-0.3	0.9	0.6
Medication for cholesterol, blood pressure or diabetes	0.6	1.1	2.5	-1.6	-1.4	-0.9	-0.1	-0.6	-0.9	-1.0	-1.2	-0.7	-0.5	-1.4	-1.1
Worry too long after embarrassment	0.6	0.9	2.3	-1.3	-1.5	-0.6	-0.5	-0.1	-1.1	-0.9	-1.4	-0.7	0.2	-0.8	-1.2
Eye problems/disorders: None of the above	0.6	0.7	3.2	0.2	-0.3	0.7	-0.5	-1.3	0.2	-1.2	-0.2	-0.1	-1.8	1.0	0.1
Angina (self-reported)	0.6	0.8	1.7	1.3	0.6	1.0	0.6	0.7	1.1	0.3	1.2	1.0	0.3	0.7	1.3
Mean time to correctly identify matches	0.6	1.1	4.2	1.1	0.6	-2.0	0.1	1.5	-1.0	-0.4	0.8	0.6	-0.1	-1.6	0.4
Number of full sisters	0.6	0.7	2.2	0.8	0.7	-1.3	1.0	1.5	0.6	0.6	0.7	0.7	0.6	0.5	0.7
Qualifications: NVQ or HND or HNC or equivalent	0.6	0.8	2.4	-1.0	-0.6	-0.8	-0.3	-1.3	-0.3	-0.4	-0.9	-0.9	-1.6	0.5	-1.0
Wears glasses or contact lenses	0.6	0.6	2.4	-0.5	-1.0	0.8	-0.8	-0.5	-0.7	-1.6	-0.7	-0.6	-0.8	-0.2	-0.7
Medication: Lisinopril	0.6	0.8	2.1	-0.4	-0.7	-0.9	-1.0	-1.1	-0.8	-1.0	-0.6	-0.8	-1.5	-0.6	-0.8
Alcohol drinker status: Never	0.6	0.8	1.9	0.7	0.2	1.3	-0.7	0.2	0.0	-1.4	0.4	1.0	-0.8	-0.8	1.4
Reaction Time	0.5	1.0	4.5	1.3	0.7	-2.1	0.3	1.2	-0.9	-0.1	1.1	0.6	-0.2	-0.9	0.5
Breast Cancer	0.5	1.2	6.3	0.3	1.2	0.7	1.0	0.5	0.8	1.6	0.1	0.4	0.8	2.5	0.6
Chronotype (morning person)	0.5	1.1	2.1	0.9	1.2	-0.4	0.7	0.9	1.4	1.4	1.1	1.0	1.2	0.8	0.7
Leg fat-free mass (left)	0.5	2.7	6.3	1.8	1.7	1.7	1.0	0.9	1.8	1.2	1.6	1.6	1.3	2.5	2.1
Townsend deprivation index at recruitment	0.5	0.6	1.3	-0.8	-0.6	-1.1	-1.0	-0.1	-0.9	-0.2	-1.1	-0.8	0.1	-1.0	-0.9
Fed-up feelings	0.5	0.9	1.8	1.2	0.8	0.5	0.3	1.2	0.1	0.7	1.3	1.0	1.3	0.4	1.1
Supplements: Glucosamine	0.5	0.7	1.8	0.5	0.3	1.2	1.3	0.3	0.7	-0.1	0.5	1.1	-1.3	-0.1	1.1
High blood pressure (mother)	0.5	0.7	3.4	-0.0	-0.3	-0.6	-1.3	-0.0	-1.0	-1.9	-0.5	-0.5	-0.7	-0.7	-0.3
Impedance of leg (left)	0.5	2.7	5.1	-1.6	-2.3	-0.6	-1.1	-0.9	-2.1	-2.0	-1.3	-1.4	-2.1	-1.7	-1.7
Leg predicted mass (left)	0.5	2.8	6.2	1.8	1.7	1.8	1.0	0.9	1.8	1.1	1.7	1.6	1.3	2.5	2.1
Hair/balding pattern: Pattern 2	0.5	0.6	2.0	-0.4	-0.6	-0.8	-1.2	-0.2	-0.4	-1.1	-0.3	-0.2	1.4	-0.8	-0.9
Financial difficulties in last 2 years	0.5	0.7	2.6	-0.4	-0.6	-1.6	-0.1	0.4	-1.5	-0.5	-0.5	-0.7	0.6	-0.8	-0.5
Falls in the last year	0.5	0.6	1.5	0.6	0.8	0.8	0.7	1.2	0.1	0.0	0.5	0.8	0.9	1.0	1.0
Loud music exposure frequency	0.5	0.5	3.2	-0.2	-0.5	-1.8	0.0	-0.3	-0.5	0.0	-0.2	-0.7	-0.9	0.2	-1.0
Number of full brothers	0.5	0.6	2.0	0.5	1.0	1.4	0.9	0.5	0.2	1.0	0.3	0.8	0.1	0.4	1.1
Illness, injury, bereavement, stress in last 2 years	0.5	0.6	1.0	-0.8	-0.8	-0.4	-0.9	-1.0	-0.6	-0.8	-0.5	-0.7	-0.9	-0.7	-0.9
Illnesses of siblings: Diabetes	0.5	0.7	3.1	-0.1	0.4	0.7	1.3	0.0	0.6	1.8	-0.4	-0.1	0.7	1.2	-0.1
Leg fat-free mass (right)	0.5	2.7	4.9	1.8	1.8	1.6	0.8	1.0	1.7	1.1	1.7	1.5	1.4	2.2	2.1
Loneliness, isolation	0.5	0.7	2.1	-0.5	-0.6	-0.7	-0.7	-0.7	-1.3	-0.8	-0.5	-0.7	-0.6	-1.5	-0.5
Mouth/teeth dental problems: Mouth ulcers	0.5	0.8	3.2	1.1	0.6	-0.7	0.2	1.8	-0.4	-0.3	0.6	0.8	0.3	-1.4	1.2
Leg predicted mass (right)	0.5	2.7	4.9	1.9	1.8	1.6	0.9	1.0	1.8	1.1	1.8	1.6	1.4	2.2	2.1
Financial situation satisfaction	0.5	0.6	3.2	-0.2	-0.3	-1.8	0.2	0.3	-1.5	-0.5	-0.3	-0.6	-0.2	-0.9	-0.5
Depressed Affect (Nagel 2018)	0.4	0.9	2.0	1.4	0.9	0.7	0.3	0.9	0.7	0.6	1.4	1.4	0.6	0.3	1.2
Intelligence (Savage-Jansen 2018)	0.4	1.1	3.4	0.7	1.0	0.3	0.4	0.7	0.9	1.1	1.2	0.5	1.8	1.7	0.8
Frequency of depressed mood in last 2 weeks	0.4	0.6	1.6	-0.2	-0.6	-1.2	-1.3	-0.0	-0.8	-1.1	-0.1	-0.3	-0.3	-1.1	-0.1
Medication for hormone replacement therapy	0.4	0.4	1.7	-0.5	-0.4	0.6	-0.5	-1.3	0.5	-0.2	-0.4	-0.4	-0.7	1.1	-0.3
Hand grip strength (right)	0.4	1.1	6.3	-0.2	0.7	1.6	0.3	-0.5	1.1	1.5	-0.1	-0.1	0.6	2.5	0.1
Age when periods started (menarche)	0.4	1.0	2.7	-1.0	-1.1	-1.6	-0.0	-1.1	-0.7	-0.6	-0.9	-0.9	-1.1	-0.7	-1.2
Sitting height	0.4	2.9	8.0	1.9	0.8	2.8	0.8	1.3	1.4	0.6	2.0	2.1	1.2	1.7	2.2
Had menopause	0.4	0.6	1.8	0.8	0.6	0.1	-0.2	1.2	-0.5	-0.8	0.9	0.4	1.3	-0.7	0.5
Neuroticism score	0.4	0.9	2.3	-1.1	-1.5	0.4	-0.9	-0.5	-1.3	-1.0	-1.0	-0.6	0.1	-1.2	-0.8
Number of live births	0.4	0.5	2.3	0.6	-0.1	-1.4	-0.1	-0.2	-0.0	-0.5	0.4	0.5	-1.5	-1.0	0.1
Breastfed as a baby	0.4	0.5	2.4	0.8	0.7	-1.6	0.2	1.0	-0.5	-0.1	0.8	0.5	0.5	0.2	0.2
Tense / ‘highly strung’	0.4	0.6	2.3	-1.1	-0.3	1.4	0.3	-0.4	-0.6	0.5	-1.5	-0.2	0.9	-0.1	-0.4
Mouth/teeth dental problems: Bleeding gums	0.4	0.6	4.4	0.3	0.3	-2.1	0.7	0.8	-0.8	0.1	0.4	0.0	0.0	0.3	-0.4
Medication: Ventolin 100micrograms inhaler	0.4	0.5	1.1	-0.6	-0.7	-1.1	-0.7	-0.2	-0.6	-0.5	-0.8	-0.7	0.3	-1.0	-0.9
Wheeze or whistling in the chest in last year	0.4	0.7	5.2	0.4	0.4	2.3	0.4	0.5	0.6	0.1	0.5	0.6	0.7	0.6	0.8
Medication: Allopurinol	0.4	0.5	2.2	0.6	0.3	0.8	-1.0	-0.6	0.6	-0.0	0.8	0.4	-1.5	0.1	0.6
Medication: Omeprazole	0.4	0.4	1.1	1.0	0.3	-0.4	0.7	0.8	0.2	-0.3	0.7	1.0	0.2	0.5	1.0
Alcohol intake frequency.	0.4	1.0	2.4	1.0	1.5	1.0	-0.1	-0.3	1.1	0.7	0.4	0.9	-0.7	1.3	1.4
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.4	0.5	1.6	-0.5	-0.5	-0.2	-0.3	-0.7	-0.6	-0.3	-0.8	-0.2	-1.2	-1.3	-0.2
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.4	0.8	2.5	-0.9	-0.8	0.6	-1.6	-1.0	-1.0	-0.9	-0.8	-0.6	-0.9	0.2	-1.0
Hearing aid user	0.4	0.5	1.7	0.2	0.5	1.1	1.0	-0.3	0.5	0.6	0.3	0.5	-1.3	0.5	0.4
Mother’s age at death	0.4	0.5	1.1	0.1	0.4	0.9	1.0	0.8	0.7	1.0	0.3	1.0	0.6	-0.2	0.6
Tinnitus: Yes, now most or all of the time	0.4	0.5	1.2	0.4	0.2	-1.1	0.9	0.5	0.2	0.3	0.2	0.8	-0.7	-1.1	0.8
Number of operations (self-reported)	0.4	0.5	2.5	0.4	-0.1	-0.6	-1.4	0.3	-0.0	-0.7	-0.0	0.1	-0.7	-1.6	-0.1
Risk taking	0.4	0.5	1.7	-0.1	-0.4	-1.0	-1.1	0.1	-1.3	-0.8	-0.1	-0.2	0.5	-1.1	0.1
Ever had prostate specific antigen (PSA) test	0.4	0.5	2.1	-0.5	-0.3	0.7	-1.0	-1.1	-0.3	-0.1	-0.4	-0.4	-1.5	-0.0	-0.1
Depression (Nagel 2018)	0.3	0.5	1.2	0.6	-0.1	0.5	-0.9	0.9	-0.2	-0.9	0.4	0.9	1.1	0.1	0.9
Alzheimer’s Disease (in mother)	0.3	0.3	2.0	-0.3	-0.3	-0.1	0.1	0.0	-0.0	1.0	-0.4	-0.1	1.4	-0.8	-0.4
Irritable Bowel Disease (IBD)	0.3	0.8	2.0	-1.2	-0.8	0.4	0.4	-0.5	-1.1	-0.0	-1.0	-1.0	0.1	-1.4	-1.2
Ulcerative Colitis (UC)	0.3	0.6	2.5	-0.8	-0.5	0.5	0.0	-0.7	-0.8	-0.4	-0.5	-0.9	0.2	-1.6	-0.8
Coronary Artery Disease (CAD)	0.3	0.4	2.4	-0.4	0.1	1.5	0.2	-0.4	-0.5	0.8	-0.8	-0.4	-0.3	0.0	-0.3
Crohns Disease (2012)	0.3	0.5	1.4	-0.8	-0.6	-0.5	0.3	0.4	-0.8	0.2	-0.9	-0.5	0.7	-0.8	-1.2
Fasting Glucose	0.3	0.3	1.1	0.4	0.2	-1.0	0.2	0.8	-0.3	-0.5	0.3	0.2	0.3	-1.1	0.2
Lupus	0.3	0.4	1.5	-0.5	-0.4	-0.5	0.3	-1.2	-0.2	-0.2	-0.6	-0.1	-1.1	-1.2	0.0
Heel T-Score	0.3	2.1	14.1	-1.1	-1.4	3.8	0.2	-1.5	0.2	-0.7	-1.5	-0.2	-1.0	-1.1	-0.3
Severe depression (siblings)	0.3	0.3	1.3	0.4	0.3	-1.2	-0.1	0.6	-0.8	-0.3	0.4	-0.1	0.9	-0.7	0.0
Impedance of leg (right)	0.3	1.5	3.4	-1.2	-1.8	-0.5	-0.6	-0.6	-1.6	-1.4	-0.9	-0.9	-1.7	-1.3	-1.3
Trunk fat percentage	0.3	1.4	4.3	-0.8	-1.1	-0.1	-1.4	-0.6	-2.1	-1.8	-1.2	-1.5	-0.7	0.4	-0.8
Heel bone mineral density (BMD) T-score, automated (left)	0.3	0.6	2.6	-0.8	-0.6	1.6	-0.2	-1.4	0.6	0.2	-0.7	-0.2	-0.9	0.3	-0.2
Arm fat percentage (right)	0.3	1.3	3.9	-0.8	-0.7	-0.4	-1.1	-0.4	-2.0	-1.3	-1.4	-1.7	-0.4	0.8	-1.0
Lung cancer (father)	0.3	0.3	1.6	0.7	0.4	-0.6	-0.2	1.3	-0.1	0.4	0.5	-0.1	1.1	-0.0	0.1
Illnesses of mother	0.3	0.4	1.1	-0.7	-0.4	-0.1	0.6	-1.1	0.6	0.7	-0.2	-0.4	-1.1	0.3	-0.7
Standing height	0.3	2.8	5.8	2.0	0.7	2.3	1.2	1.3	1.4	0.2	2.3	2.3	0.7	1.2	2.4
Peak expiratory flow (PEF)	0.3	0.7	2.8	0.5	0.5	1.4	0.5	0.1	0.7	0.8	0.5	0.9	-0.4	1.7	0.9
Pulse wave reflection index	0.3	0.4	1.6	-0.3	0.4	-1.3	-0.5	0.5	-0.4	0.9	-0.1	-0.6	0.9	0.5	-0.6
Glaucoma (self-reported)	0.3	0.3	0.9	0.1	0.6	-0.9	0.4	0.7	0.3	0.7	0.5	0.3	0.9	-0.3	0.2
Gout (self-reported)	0.3	0.4	2.3	0.4	0.4	0.3	-1.5	-0.3	0.0	-0.4	0.3	-0.0	-1.1	0.4	0.3
Body fat percentage	0.3	1.2	3.7	-0.8	-0.9	-0.2	-1.2	-0.6	-1.9	-1.4	-1.2	-1.5	-0.6	0.5	-0.9
Seen a psychiatrist for nerves, anxiety, tension or depression	0.3	0.4	1.0	0.9	0.7	0.6	0.4	0.5	0.7	0.7	0.7	1.0	0.3	-0.2	0.9
Reason for reducing amount of alcohol drunk: Health precaution	0.3	0.3	1.4	-0.2	-0.4	1.2	-0.9	-0.0	-0.3	-0.7	-0.3	0.3	-0.9	-0.3	0.2
Mouth/teeth dental problems: Loose teeth	0.3	0.3	1.2	-0.3	0.4	-0.2	0.4	0.6	-0.3	0.7	-0.6	-0.4	1.1	0.4	-0.6
Medication: Blood pressure	0.3	0.5	1.5	1.2	1.2	0.3	-0.1	0.9	0.2	0.0	1.0	0.4	0.3	0.2	0.7
Migraine (self-reported)	0.3	0.4	0.9	-0.7	-0.3	-0.0	-0.1	-0.6	-0.4	-0.8	-0.9	-0.7	-0.9	-0.4	-0.6
Heart disease (mother)	0.3	0.4	1.6	-0.1	-0.1	0.1	-0.9	0.1	-0.6	-1.3	-0.4	0.1	-1.3	-0.6	0.2
Comparative height size at age 10	0.3	1.9	7.5	1.5	0.2	2.7	1.1	1.3	0.6	-0.5	1.8	1.7	-0.3	-0.2	1.8
Suffer from ‘nerves’	0.3	0.5	1.7	-0.7	-1.0	-1.0	0.2	0.2	-0.7	-0.2	-0.2	-0.4	-0.2	-1.3	-0.7
Overall health rating	0.3	0.7	2.1	0.8	0.6	-0.3	1.4	1.4	0.2	0.0	0.8	1.1	0.5	-0.3	1.2
Chest pain or discomfort	0.3	0.4	1.6	0.2	0.1	1.1	0.8	0.7	-0.2	-0.5	0.0	0.1	0.6	-1.3	-0.1
Illnesses of father: Heart disease	0.3	0.4	1.6	0.8	0.2	0.0	0.1	0.9	0.1	0.2	1.0	0.7	-0.3	-1.3	0.7
Ever had stillbirth, spontaneous miscarriage or termination	0.3	0.3	1.1	-0.4	-0.7	0.4	-0.7	-0.9	-0.6	-0.3	-0.4	-0.1	-1.1	-0.1	-0.3
Friendships satisfaction	0.3	0.3	1.1	-0.2	-0.5	-0.7	-0.5	0.3	-1.1	-0.7	0.0	-0.5	0.5	-0.8	-0.6
Asthma (self-reported)	0.3	0.5	1.6	0.5	0.7	0.7	0.5	0.5	0.7	0.6	0.3	0.4	1.2	1.3	0.3
Osteoporosis (self-reported)	0.3	0.4	2.5	-0.5	-0.5	-1.6	-0.3	0.0	-0.8	-0.3	-0.5	-0.4	-0.0	0.1	-0.4
Medication: Gliclazide	0.3	0.4	1.4	0.7	0.2	-0.9	0.8	1.2	-0.6	0.4	0.6	0.1	0.2	0.2	0.6
Illnesses of father: None of the above (group 1)	0.3	0.4	1.4	-0.9	-0.4	-0.4	-0.8	-0.5	-0.3	-0.0	-0.7	-0.8	-0.0	0.2	-1.2
Pain type(s) experienced in last month: Hip pain	0.3	0.3	2.1	0.4	0.6	-1.5	-0.2	0.8	-0.8	0.2	0.3	0.1	0.1	0.1	0.2
High cholesterol (Self-reported)	0.3	0.6	2.9	-0.6	-0.2	0.3	-0.3	-0.6	-0.9	0.2	-1.0	-1.0	-0.4	1.7	-0.8
Bipolar Disorder (2018)	0.2	0.3	1.6	-0.1	0.0	0.3	-1.0	-0.5	0.0	-0.3	-0.3	-0.3	-0.5	-1.3	-0.2
Crohns Disease (2017)	0.2	0.5	1.2	-1.0	-0.7	0.3	0.8	0.0	-0.8	0.4	-1.1	-0.5	0.3	-0.8	-1.1
Ovarian Cancer	0.2	0.2	0.5	0.4	-0.3	-0.4	-0.7	0.5	0.1	-0.6	0.2	0.3	0.7	0.7	0.2
Age at First Birth	0.2	0.3	1.0	0.3	-0.2	0.9	0.9	0.3	0.2	-0.1	0.5	0.8	-0.1	-1.0	0.3
Mean Putamen Volume	0.2	0.2	0.9	-0.1	0.2	0.7	0.2	0.1	0.3	0.4	0.0	0.6	0.9	-0.1	0.4
HDL Cholesterol	0.2	0.3	1.0	-0.1	-0.6	-1.0	0.9	0.6	-0.3	-0.3	0.2	0.1	-0.4	-0.7	-0.1
LDL Cholesterol	0.2	0.3	0.7	-0.8	-0.2	0.4	-0.8	-0.3	-0.7	-0.3	-0.5	-0.9	0.1	0.2	-0.5
Rheumatoid Arthritis	0.2	0.3	1.1	-0.4	-0.6	-0.0	-1.0	-0.5	-0.0	-0.6	-0.4	-0.3	-0.6	-1.0	-0.0
Schizophrenia (2014)	0.2	0.5	2.2	0.6	0.3	1.3	-1.5	-0.2	0.2	-0.5	0.3	0.1	-0.4	0.4	0.8
Type 2 Diabetes (T2D) (2012)	0.2	0.2	0.8	-0.4	-0.0	0.4	-0.2	0.7	-0.9	-0.1	-0.9	0.1	0.5	-0.2	-0.2
Waist Hip Ratio (WHR)	0.2	1.0	3.8	0.2	-0.7	-0.9	-0.4	0.9	-1.0	-1.4	-0.1	0.1	-1.9	-1.7	0.2
Allergy or Eczema	0.2	0.5	3.2	0.2	-0.6	-1.8	-0.7	-0.4	0.1	-1.1	0.3	-0.1	-0.3	-0.4	-0.3
Respiratory disease	0.2	0.3	0.9	0.5	0.5	0.3	-0.3	0.6	0.8	0.2	0.4	0.7	0.7	0.9	0.6
Neuroticism	0.2	0.4	2.1	-0.1	-0.6	1.2	-0.2	0.2	-0.3	-0.4	-0.2	0.1	1.4	-0.1	-0.2
Tanning	0.2	2.0	3.4	1.0	1.7	1.4	1.5	0.8	1.8	1.4	1.2	1.4	0.9	1.8	1.5
Other serious medical condition/disability diagnosed by doctor	0.2	0.2	1.0	0.5	0.0	0.6	-0.1	1.0	-0.2	-0.2	0.5	0.2	0.2	-0.8	0.5
Eye problems/disorders: Diabetes related eye disease	0.2	0.2	0.6	0.4	-0.3	-0.8	-0.0	0.7	-0.6	-0.2	0.7	-0.2	0.7	-0.2	0.1
Pack years adult smoking proportion	0.2	0.3	0.9	-0.2	-0.4	-0.4	-0.3	0.7	-0.9	-0.2	-0.1	-0.3	0.6	0.7	-0.6
Hayfever, allergic rhinitis or eczema	0.2	0.5	1.4	0.1	-0.7	-0.9	-0.8	-1.1	0.2	-1.2	0.3	-0.1	-0.9	-0.3	-0.3
Diverticular disease/diverticulitis (self-reported)	0.2	0.2	1.4	0.3	0.1	0.4	0.2	-0.2	0.2	-0.3	0.2	-0.1	-0.8	-1.2	0.3
Medication: Atenolol	0.2	0.3	1.1	0.2	0.5	-0.8	-0.3	0.3	0.0	0.9	0.4	-0.5	0.1	1.0	-0.3
Medication: Levothyroxine sodium	0.2	0.3	0.9	0.4	0.3	-0.0	1.0	0.6	0.5	0.6	0.2	0.8	0.3	0.4	0.3
Number of incorrect matches in round	0.2	0.3	0.8	-0.7	-0.6	-0.9	-0.1	-0.4	-0.4	-0.6	-0.6	-0.4	-0.5	-0.6	-0.9
Heel bone mineral density (BMD) T-score, automated (right)	0.2	0.4	3.2	-0.4	-0.3	1.8	0.3	-0.7	0.7	0.1	-0.3	0.1	-0.4	0.6	-0.0
Qualifications: None of the above	0.2	0.4	1.0	-0.7	-0.3	0.8	-0.4	-1.0	0.1	-0.8	-0.9	-0.1	-0.2	-0.9	-0.2
Heart attack	0.2	0.2	1.3	0.6	0.3	0.1	1.1	0.2	0.4	0.2	0.3	0.4	0.0	-0.1	0.7
Illnesses of siblings	0.2	0.2	0.6	-0.5	-0.2	-0.3	-0.8	-0.7	0.5	0.2	0.1	-0.1	-0.7	0.6	-0.4
Weight	0.2	1.0	4.4	0.9	0.9	1.7	0.3	0.6	0.2	0.3	0.6	0.4	0.7	2.1	1.2
Hip circumference	0.2	0.9	3.0	0.9	1.0	1.7	0.5	0.6	0.3	0.6	0.6	0.4	0.7	1.6	1.1
Time employed in main current job	0.2	0.3	1.0	0.3	0.4	-0.7	0.6	0.6	-0.0	0.6	0.4	0.2	-0.3	1.0	0.1
Worrier / anxious feelings	0.2	0.4	0.8	-0.4	-0.9	-0.8	0.4	0.8	-0.5	-0.5	-0.4	0.1	0.7	-0.7	-0.3
Forced expiratory volume in 1-second (FEV1)	0.2	0.6	4.7	-0.3	0.1	0.3	-0.2	-1.0	0.5	0.7	0.0	0.2	-0.8	2.2	0.0
Serious illness, injury or assault of a close relative in last 2 years	0.2	0.2	0.8	0.9	0.5	-0.3	0.0	0.1	0.1	-0.4	0.8	0.1	-0.1	0.4	0.6
Asthma	0.2	0.5	1.2	0.6	0.7	0.5	0.4	0.6	0.7	0.7	0.3	0.4	1.1	1.1	0.4
Medication: Lansoprazole	0.2	0.3	0.5	0.7	0.1	0.6	-0.5	0.3	0.4	-0.5	0.6	0.6	-0.1	-0.6	0.6
Prospective memory result	0.2	0.2	1.4	-0.2	-0.4	1.2	0.3	0.1	-0.6	-0.7	-0.3	0.0	-0.2	-0.4	0.2
Birth weight of first child	0.2	0.4	0.9	-0.6	-0.6	-0.3	-1.0	-0.5	-0.2	-0.6	-0.6	-0.8	0.1	0.2	-0.9
Shortness of breath walking on level ground	0.2	0.2	0.5	-0.5	-0.4	0.6	-0.1	-0.1	-0.6	-0.0	-0.5	-0.7	0.3	0.3	-0.7
Qualifications: College or University degree	0.2	0.5	1.5	0.5	-0.3	-0.7	-0.0	1.2	-0.8	-0.7	0.5	0.1	1.1	-0.9	0.1
Medication: Seretide 50 evohaler	0.2	0.2	0.8	-0.3	-0.1	0.1	0.5	-0.6	0.8	0.7	-0.3	0.2	0.9	0.2	-0.0
Had major operations	0.2	0.3	1.1	0.3	0.2	-0.0	0.8	0.6	0.5	0.5	0.3	0.4	-1.1	-0.0	0.2
Family relationship satisfaction	0.2	0.2	1.1	-0.3	-0.5	-0.4	-0.8	-0.1	-1.0	-0.4	0.1	-0.4	-0.0	-0.1	-0.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.2	0.2	0.8	0.6	-0.0	0.6	0.6	0.2	0.1	-0.9	0.4	0.5	0.2	-0.2	0.5
Arm fat percentage (left)	0.2	0.8	2.2	-0.7	-0.4	-0.1	-0.8	-0.3	-1.5	-0.7	-1.2	-1.4	-0.0	1.1	-0.8
Handedness (chirality/laterality): Left-handed	0.2	0.3	1.5	-0.3	-0.7	0.0	0.6	0.1	-1.2	-0.6	0.1	-0.6	-0.2	-0.6	-0.1
Mood swings	0.2	0.3	0.9	0.8	0.8	0.2	0.2	0.5	0.6	0.3	1.0	0.8	0.0	0.1	0.5
Long-standing illness, disability or infirmity	0.2	0.3	0.8	0.9	0.6	-0.3	0.1	0.7	0.1	0.3	0.5	0.4	-0.1	0.3	0.8
Diabetes diagnosed by doctor	0.2	0.3	1.1	0.5	0.6	0.3	1.0	1.0	0.0	0.6	0.4	0.4	-0.2	-0.1	0.7
Eye problems/disorders: Cataract	0.2	0.3	1.2	-0.3	0.2	0.6	0.3	0.3	0.4	0.9	0.0	0.4	1.1	0.2	0.1
Number of self-reported non-cancer illnesses	0.2	0.3	2.1	0.5	0.5	-0.0	-0.0	1.1	-0.3	-0.0	0.1	0.1	1.4	0.1	0.2
Eye problems/disorders: Glaucoma	0.2	0.3	1.0	0.4	0.8	-0.6	0.1	1.0	-0.2	0.3	0.7	0.4	0.1	-0.6	0.5
Leg fat percentage (left)	0.2	0.7	2.5	-0.7	-0.5	0.4	-0.7	-0.2	-1.6	-0.8	-1.1	-1.3	-0.5	0.6	-0.7
Unable to work because of sickness or disability	0.2	0.3	0.6	0.6	0.3	0.4	0.7	0.8	0.1	-0.2	0.6	0.6	0.6	0.0	0.7
Cholesterol lowering medication	0.2	0.3	0.8	-0.5	-0.4	-0.2	-0.5	0.0	-0.9	-0.1	-0.7	-0.6	-0.2	0.9	-0.5
Medication: Omeprazole (e.g. Zanprol)	0.2	0.3	1.1	0.6	-0.4	-0.9	-0.6	0.1	-0.5	-1.1	0.2	0.2	-0.0	-0.1	0.4
Heart attack/myocardial infarction (self-reported)	0.2	0.2	1.3	0.6	0.3	0.2	1.1	0.2	0.4	0.2	0.3	0.5	0.1	0.1	0.6
Bipolar Disorder or Schizophrenia	0.1	0.3	1.9	0.3	0.1	1.1	-1.4	-0.4	0.1	-0.5	0.0	-0.1	-0.2	-0.4	0.4
Neuroticism (Nagel 2018)	0.1	0.3	1.2	0.2	-0.5	0.4	0.2	0.7	-0.2	-0.4	0.1	0.6	1.1	-0.6	0.1
Schizophrenia (2018)	0.1	0.3	1.2	0.5	0.1	1.1	-1.0	-0.0	0.1	-0.4	0.3	0.2	0.1	0.5	0.7
Blood Red Count	0.1	0.6	2.7	-0.6	-0.5	0.6	0.2	1.4	-1.6	-0.4	-0.6	-0.3	-0.4	-0.9	-0.4
BMI	0.1	0.7	3.3	-0.2	0.2	-0.1	-1.0	-0.8	-0.9	-0.4	-1.0	-1.1	-0.5	1.8	-0.0
Hypothyroidism (self reported)	0.1	0.1	0.4	-0.4	-0.4	-0.2	-0.1	-0.4	-0.1	0.3	-0.6	-0.1	0.1	-0.5	-0.6
Type 2 Diabetes (T2D) (2018)	0.1	0.3	0.6	0.4	0.5	-0.1	0.8	0.6	-0.8	0.0	0.4	0.0	-0.5	-0.6	0.6
Average weekly fortified wine intake	0.1	0.1	0.4	0.1	0.4	0.6	-0.1	0.2	0.1	0.5	-0.0	0.0	-0.3	-0.6	0.1
Maternal smoking around birth	0.1	0.2	0.8	0.2	0.4	0.3	0.8	0.3	-0.1	0.1	-0.1	-0.1	0.3	-0.9	-0.2
Tinnitus: Yes, but not now, but have in the past	0.1	0.1	0.4	0.2	-0.0	-0.4	0.7	0.0	0.0	-0.2	0.2	0.3	-0.0	0.6	0.3
Body mass index (BMI)	0.1	0.4	3.3	0.2	0.9	0.6	-0.1	0.2	-0.3	0.4	-0.2	-0.4	0.6	1.8	0.3
Trunk fat mass	0.1	0.4	1.5	0.0	-0.2	0.7	-0.7	-0.0	-1.0	-1.0	-0.4	-0.6	-0.1	1.2	0.2
Waist circumference	0.1	0.3	1.0	0.5	0.5	1.0	0.1	0.6	-0.3	-0.0	-0.1	0.1	-0.1	0.8	0.7
Forced vital capacity (FVC)	0.1	0.5	2.9	-0.5	-0.3	0.3	-0.6	-1.0	0.4	0.0	0.0	0.1	-0.9	1.7	-0.2
Allergy	0.1	0.3	1.2	-0.7	-0.3	-0.4	-0.1	0.1	-1.1	0.1	-0.9	-0.5	-0.4	-0.9	-0.2
Medication: Simvastatin	0.1	0.2	1.5	0.2	0.1	0.3	-0.2	0.1	-0.4	0.5	0.1	-0.1	-0.3	1.2	0.1
Father’s age at death	0.1	0.2	0.7	0.5	0.3	0.2	-0.4	-0.2	0.8	-0.2	0.4	0.0	0.3	0.6	0.5
Forced expiratory volume in 1-second (FEV1), Best measure	0.1	0.4	2.9	-0.3	-0.1	0.2	-0.6	-0.9	0.1	0.4	0.1	0.1	-0.7	1.7	0.0
Arm fat mass (right)	0.1	0.4	2.5	0.1	0.3	0.5	-0.3	0.2	-0.8	-0.3	-0.3	-0.6	0.4	1.6	0.1
Headache pain in last month	0.1	0.2	1.0	-0.5	-0.2	0.7	-0.4	-0.2	0.4	-0.0	-0.5	-0.3	-0.3	1.0	-0.5
Forced vital capacity (FVC), Best measure	0.1	0.4	2.2	-0.2	-0.2	0.1	-0.4	-0.7	0.0	-0.2	0.3	0.3	-1.3	1.5	0.1
Leg fat percentage (right)	0.1	0.4	1.4	-0.4	-0.2	0.4	-0.4	-0.2	-1.2	-0.5	-0.8	-1.0	-0.4	1.0	-0.4
Neck or shoulder pain in last month	0.1	0.2	1.0	0.3	-0.1	0.4	-0.8	-0.2	0.0	-1.0	0.2	0.2	-0.1	0.1	0.6
Whole body fat mass	0.1	0.4	1.5	-0.2	-0.2	0.5	-0.6	-0.0	-1.1	-0.7	-0.6	-0.7	0.1	1.2	-0.1
Leg fat mass (right)	0.1	0.4	3.4	0.4	0.5	0.7	0.1	0.4	-0.3	0.1	-0.0	-0.2	0.3	1.8	0.4
Leg pain on walking	0.1	0.2	1.0	-0.5	-0.2	0.3	0.0	0.1	-1.0	0.3	-0.7	-0.3	0.3	-0.1	-0.2
Forced expiratory volume in 1-second (FEV1), predicted	0.1	0.2	0.7	-0.3	-0.5	0.8	0.1	-0.5	0.1	0.0	-0.2	-0.1	-0.2	0.6	-0.3
Qualifications: nursing, teaching	0.1	0.1	1.0	0.3	0.2	-0.5	-0.1	-0.2	0.2	0.1	0.2	-0.3	-0.1	1.0	-0.1
Arm fat mass (left)	0.1	0.4	3.0	-0.1	0.3	0.7	-0.3	0.0	-0.7	-0.1	-0.4	-0.7	0.5	1.7	0.0
Miserableness	0.1	0.2	0.5	0.3	0.1	0.6	-0.1	0.7	-0.5	0.3	0.2	0.4	0.6	0.0	0.4
Pack years of smoking	0.1	0.2	0.6	-0.1	-0.4	-0.3	-0.3	0.6	-0.8	-0.3	0.1	-0.1	0.2	0.6	-0.5
Leg fat mass (left)	0.1	0.3	2.3	0.1	0.3	0.7	-0.2	0.3	-0.6	-0.2	-0.2	-0.5	0.3	1.5	0.3
Blood Platelet Count	0.0	0.3	0.8	0.7	0.7	0.9	-0.4	-0.4	0.4	0.5	0.3	0.6	-0.5	0.7	0.3
Lung FEV1/FVC ratio	0.0	0.2	1.1	-0.2	0.1	1.0	-0.1	-0.2	-0.2	0.4	-0.6	-0.2	0.3	0.5	0.1
Lung FVC	0.0	0.2	0.9	-0.4	0.0	-0.7	-0.9	-0.4	0.0	0.2	0.0	-0.0	-0.8	0.5	-0.3
Hair Pigment	0.0	0.8	2.4	-0.9	-0.8	-0.4	-0.5	-0.5	-1.5	-0.8	-0.8	-1.2	-0.6	1.0	-1.0
Hypothyroidism/myxoedema (self-reported)	0.0	0.0	0.2	0.0	-0.1	0.1	0.4	0.1	0.1	0.0	-0.1	0.4	-0.2	-0.2	0.0

Hub : Genes

MKLN1-AS2

Models

Trait associations