Best TWAS P=1.99e-08 · Best GWAS P=1.03e-06 conditioned to 0.445
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Thyroid | RP1-239B22.5 | 0.08 | 0.07 | enet | 16 | 0.08 | 1.8e-06 | 4.8 | -5.4 | 5.2e-08 | -0.85 | 0.01 | 0.97 | FALSE |
| 2 | The Cancer Genome Atlas | Bladder Urothelial Carcinoma | DKFZp686O24166 | 0.04 | 0.00 | blup | 71 | 0.02 | 7.1e-03 | -3.9 | -5.6 | 2.0e-08 | -0.79 | 0.01 | 0.62 | TRUE |
| 3 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | DKFZp686O24166 | 0.03 | 0.01 | blup | 72 | 0.03 | 2.4e-04 | 4.9 | -5.1 | 2.8e-07 | -0.82 | 0.01 | 0.90 | FALSE |
| 4 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | NUCB2 | 0.10 | 0.04 | enet | 8 | 0.05 | 2.6e-06 | -4.2 | -5.2 | 2.6e-07 | -0.67 | 0.08 | 0.75 | FALSE |