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chr11:46,033,104-48,783,497

Best TWAS P=2.95e-13 · Best GWAS P=1.27e-13 conditioned to 0.000663

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	AGBL2	0.03	0.02	enet	7	0.03	7.9e-05	-6.1	-6.4	1.6e-10	0.71	0.22	0.76	FALSE
2	CommonMind	Brain Pre-frontal Cortex	LRP4	0.04	0.05	lasso	4	0.04	6.6e-06	-5.3	-5.3	1.2e-07	0.55	0.96	0.02	FALSE
3	CommonMind	Brain Pre-frontal Cortex	PTPRJ	0.06	0.04	lasso	4	0.05	7.6e-07	-6.5	-7.1	1.6e-12	0.65	0.03	0.97	FALSE
4	GTEx	Adipose Visceral Omentum	ACP2	0.08	0.05	lasso	5	0.05	1.4e-03	-6.0	5.7	1.1e-08	-0.83	0.13	0.69	FALSE
5	GTEx	Breast Mammary Tissue	CKAP5	0.09	0.05	enet	16	0.03	1.3e-02	-4.3	-5.1	3.0e-07	0.57	0.47	0.28	FALSE
6	GTEx	Breast Mammary Tissue (Female)	ACP2	0.03	0.00	lasso	1	0.02	1.0e-01	-6.9	6.9	5.8e-12	-0.78	0.03	0.11	FALSE
7	GTEx	Cells EBV-transformed lymphocytes	ACP2	0.17	0.03	lasso	6	0.03	4.2e-02	-2.7	6.6	5.2e-11	-0.83	0.05	0.86	FALSE
8	GTEx	Cells Transformed fibroblasts	PACSIN3	0.07	0.00	enet	7	0.01	1.2e-01	-5.1	5.5	4.6e-08	-0.33	0.12	0.09	FALSE
9	GTEx	Esophagus Gastroesophageal Junction	NUP160	0.18	0.02	enet	18	0.11	7.1e-05	3.0	-6.0	1.5e-09	0.25	0.27	0.05	FALSE
10	GTEx	Esophagus Mucosa	ACP2	0.07	0.04	enet	11	0.04	6.2e-04	-6.4	6.4	1.6e-10	-0.93	0.02	0.97	FALSE
11	GTEx	Heart Left Ventricle	ACP2	0.11	0.06	enet	18	0.10	9.2e-06	-7.2	5.4	6.2e-08	-0.84	0.04	0.95	FALSE
12	GTEx	Muscle Skeletal	FNBP4	0.05	0.03	lasso	5	0.04	5.0e-05	-6.3	-7.3	3.0e-13	0.67	0.21	0.69	TRUE
13	GTEx	Prostate	CELF1	0.17	0.16	lasso	2	0.12	6.2e-04	-5.1	-5.1	2.9e-07	0.57	0.18	0.09	FALSE
14	GTEx	Skin Not Sun Exposed Suprapubic	SLC39A13	0.07	0.11	lasso	2	0.10	5.2e-06	-6.3	-6.3	2.8e-10	0.80	0.20	0.48	FALSE
15	GTEx	Testis	C1QTNF4	0.14	0.12	lasso	4	0.11	1.6e-05	5.7	5.8	8.8e-09	-0.27	0.83	0.01	FALSE
16	GTEx	Thyroid	ACP2	0.19	0.14	lasso	4	0.12	3.0e-09	-6.0	5.5	3.6e-08	-0.82	0.73	0.27	FALSE
17	METSIM	Adipose	NR1H3	0.03	0.03	lasso	6	0.04	4.7e-06	4.2	-5.9	2.8e-09	0.58	0.11	0.85	FALSE
18	NTR	Blood	ACP2	0.01	0.00	enet	7	0.01	2.5e-03	-6.4	5.5	4.3e-08	-0.90	0.02	0.96	FALSE
19	NTR	Blood	DDB2	0.01	0.00	lasso	7	0.01	2.2e-03	-5.3	6.4	1.4e-10	-0.86	0.05	0.84	FALSE
20	ROSMAP	Brain Pre-frontal Cortex	FNBP4	0.04	0.04	lasso	3	0.04	8.2e-06	5.7	-5.5	4.9e-08	0.27	0.99	0.00	FALSE
21	ROSMAP	Brain Pre-frontal Cortex	PTPMT1	0.03	0.02	blup	270	0.02	3.8e-04	-6.3	-5.5	2.9e-08	0.78	0.09	0.85	FALSE
22	ROSMAP	Brain Pre-frontal Cortex	LRP4	0.04	0.06	blup	286	0.05	3.5e-07	-5.2	-6.2	4.1e-10	0.79	0.31	0.68	FALSE
23	ROSMAP	Brain Pre-frontal Cortex	DDB2	0.04	0.03	enet	15	0.03	7.1e-05	-5.2	6.0	1.6e-09	-0.56	0.70	0.25	FALSE
24	ROSMAP	Brain Pre-frontal Cortex	ZNF408	0.04	0.02	blup	243	0.03	5.0e-05	-4.3	5.7	1.6e-08	-0.61	0.09	0.90	FALSE
25	YFS	Blood	DDB2	0.02	0.00	bslmm	306	0.01	1.9e-04	-7.3	5.7	1.1e-08	-0.66	0.02	0.91	FALSE
26	The Cancer Genome Atlas	Colon Adenocarcinoma	PSMC3	0.09	0.05	blup	39	0.05	1.0e-03	4.6	-6.2	4.1e-10	0.35	0.09	0.08	FALSE
27	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	ACP2	0.02	0.03	lasso	1	0.02	1.5e-03	-6.0	6.0	1.6e-09	-0.83	0.03	0.68	FALSE
28	The Cancer Genome Atlas	Prostate Adenocarcinoma	AGBL2	0.04	0.03	blup	49	0.03	7.8e-04	5.1	-6.5	1.1e-10	0.50	0.10	0.48	FALSE
29	The Cancer Genome Atlas	Testicular Germ Cell Tumors	MADD	0.21	0.04	blup	64	0.07	1.3e-03	-7.2	6.4	1.6e-10	-0.84	0.01	0.82	FALSE
30	The Cancer Genome Atlas	Thyroid Carcinoma	DDB2	0.06	0.04	enet	17	0.03	1.3e-03	-7.3	-5.4	7.8e-08	0.85	0.00	0.99	FALSE
31	The Cancer Genome Atlas	Uterine Corpus Endometrial Carcinoma	ZNF408	0.27	0.01	blup	27	0.09	1.5e-03	-4.5	5.4	6.1e-08	-0.57	0.00	0.35	FALSE