Best TWAS P=2.45e-09 · Best GWAS P=2.36e-09 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | FMNL3 | 0.03 | 0.03 | bslmm | 343 | 0.03 | 3.2e-04 | -3.3 | 5.4 | 5.8e-08 | -0.02 | 0.67 | 0.12 | TRUE |
| 2 | GTEx | Nerve Tibial | RP4-605O3.4 | 0.11 | 0.00 | lasso | 3 | 0.00 | 1.7e-01 | 6.0 | 5.9 | 4.5e-09 | 0.84 | 0.01 | 0.93 | FALSE |
| 3 | GTEx | Prostate | CERS5 | 0.19 | 0.08 | lasso | 4 | 0.02 | 1.2e-01 | 5.9 | 5.7 | 1.3e-08 | 0.98 | 0.02 | 0.76 | FALSE |
| 4 | GTEx | Skin Sun Exposed Lower leg | SMARCD1 | 0.07 | 0.02 | lasso | 2 | 0.03 | 1.4e-03 | -4.8 | -5.3 | 1.1e-07 | -0.69 | 0.06 | 0.80 | FALSE |
| 5 | GTEx | Testis | SMARCD1 | 0.22 | 0.10 | enet | 22 | 0.10 | 2.6e-05 | 4.2 | -5.3 | 9.7e-08 | -0.85 | 0.01 | 0.98 | FALSE |
| 6 | GTEx | Testis | CERS5 | 0.12 | 0.06 | lasso | 6 | 0.07 | 4.0e-04 | 5.9 | 6.0 | 2.5e-09 | 0.98 | 0.01 | 0.94 | TRUE |
| 7 | GTEx | Whole Blood | RP4-605O3.4 | 0.04 | 0.04 | lasso | 4 | 0.01 | 1.5e-02 | 5.9 | 5.8 | 8.1e-09 | 1.00 | 0.01 | 0.97 | FALSE |
| 8 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | LIMA1 | 0.08 | 0.10 | blup | 59 | 0.10 | 1.8e-11 | 5.5 | -5.3 | 1.0e-07 | -0.90 | 0.07 | 0.93 | FALSE |
| 9 | The Cancer Genome Atlas | Thyroid Carcinoma | FMNL3 | 0.07 | 0.08 | lasso | 2 | 0.08 | 7.5e-08 | -4.9 | 5.2 | 1.8e-07 | -0.06 | 0.01 | 0.99 | FALSE |