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chr13:114,302,502-115,106,996

Best TWAS P=1.83e-08 · Best GWAS P=4.18e-08 conditioned to 0.252

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Artery Tibial	CDC16	0.23	0.26	lasso	8	0.25	2.8e-19	5.0	5.2	2.2e-07	0.77	0.02	0.98	FALSE
2	GTEx	Cells EBV-transformed lymphocytes	CDC16	0.14	0.09	lasso	3	0.10	2.9e-04	5.3	5.5	4.0e-08	0.82	0.01	0.98	FALSE
3	GTEx	Cells Transformed fibroblasts	CDC16	0.17	0.13	lasso	6	0.15	4.6e-11	5.3	5.5	3.9e-08	0.79	0.01	0.99	FALSE
4	GTEx	Colon Sigmoid	UPF3A	0.15	0.10	lasso	8	0.08	8.3e-04	5.3	5.6	1.8e-08	0.88	0.01	0.98	TRUE
5	GTEx	Colon Transverse	CDC16	0.18	0.23	lasso	5	0.21	3.2e-10	5.3	5.2	2.5e-07	0.77	0.02	0.98	FALSE
6	GTEx	Esophagus Gastroesophageal Junction	UPF3A	0.20	0.07	lasso	6	0.06	4.5e-03	5.3	5.4	5.7e-08	0.81	0.01	0.95	FALSE
7	GTEx	Esophagus Mucosa	CDC16	0.35	0.46	lasso	6	0.46	1.0e-33	5.3	5.4	8.0e-08	0.79	0.01	0.99	FALSE
8	GTEx	Pancreas	CDC16	0.09	0.14	lasso	3	0.06	1.8e-03	5.3	5.3	1.0e-07	0.76	0.02	0.96	FALSE
9	GTEx	Prostate	CDC16	0.17	0.16	lasso	3	0.11	1.4e-03	5.3	5.3	1.0e-07	0.76	0.02	0.92	FALSE
10	GTEx	Thyroid	CDC16	0.12	0.13	lasso	2	0.11	8.2e-09	5.3	5.3	1.1e-07	0.77	0.01	0.99	FALSE
11	GTEx	Whole Blood	CDC16	0.31	0.20	lasso	5	0.20	4.4e-18	5.3	5.1	2.8e-07	0.71	0.01	0.99	FALSE
12	NTR	Blood	CDC16	0.10	0.20	bslmm	209	0.20	3.1e-63	5.3	5.3	9.9e-08	0.76	0.01	0.99	FALSE
13	YFS	Blood	CDC16	0.28	0.54	enet	30	0.55	1.1e-220	5.3	5.1	2.8e-07	0.76	0.01	0.99	FALSE
14	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	CDC16	0.05	0.08	lasso	4	0.08	7.2e-09	5.3	5.2	2.2e-07	0.72	0.01	0.99	FALSE
15	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	CDC16	0.05	0.04	blup	49	0.05	2.0e-06	5.0	5.5	3.3e-08	0.87	0.02	0.98	FALSE
16	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	CDC16	0.03	0.04	lasso	3	0.04	1.3e-05	5.0	5.6	2.9e-08	0.92	0.02	0.98	FALSE
17	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	CDC16	0.11	0.09	blup	49	0.09	1.8e-04	5.0	5.3	9.7e-08	0.76	0.02	0.96	FALSE
18	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	CDC16	0.07	0.03	blup	49	0.05	6.3e-03	5.3	5.2	2.2e-07	0.90	0.01	0.84	FALSE
19	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	UPF3A	0.10	0.09	lasso	1	0.08	3.8e-04	5.5	5.5	4.2e-08	1.00	0.01	0.78	FALSE
20	The Cancer Genome Atlas	Thyroid Carcinoma	CDC16	0.06	0.09	lasso	3	0.09	3.3e-09	5.3	5.5	2.9e-08	0.83	0.02	0.98	FALSE