[Hub]/) : Traits : Systolic blood pressure, automated reading :

chr15:62,716,641-64,123,980

Best TWAS P=2.25e-09 · Best GWAS P=2.64e-08 conditioned to 0.247

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex LACTB 0.12 0.14 lasso 2 0.14 1.2e-16 -5.4 -5.2 2.7e-07 -0.80 0.01 0.99 FALSE
2 GTEx Adipose Subcutaneous LACTB 0.11 0.10 enet 11 0.07 2.3e-06 -5.4 -5.6 2.4e-08 -0.86 0.01 0.99 FALSE
3 GTEx Adipose Visceral Omentum LACTB 0.16 0.11 lasso 3 0.09 2.7e-05 -5.4 -5.2 2.0e-07 -0.87 0.01 0.99 FALSE
4 GTEx Esophagus Muscularis LACTB 0.12 0.05 lasso 9 0.06 1.3e-04 -5.4 -5.8 8.3e-09 -0.89 0.02 0.98 FALSE
5 GTEx Heart Atrial Appendage LACTB 0.17 0.05 lasso 5 0.08 2.2e-04 -5.4 -5.3 1.3e-07 -0.91 0.01 0.99 FALSE
6 GTEx Lung LACTB 0.10 0.09 lasso 4 0.08 9.2e-07 -5.4 -5.6 2.6e-08 -0.88 0.01 0.99 FALSE
7 GTEx Thyroid LACTB 0.10 0.03 lasso 4 0.02 1.0e-02 -5.4 -5.5 4.5e-08 -0.89 0.01 0.98 FALSE
8 METSIM Adipose LACTB 0.17 0.20 lasso 4 0.20 1.3e-28 -5.4 -5.3 1.2e-07 -0.85 0.01 0.99 FALSE
9 YFS Blood LACTB 0.07 0.06 lasso 6 0.09 1.0e-26 -5.4 -5.8 6.6e-09 -0.89 0.01 0.99 FALSE
10 The Cancer Genome Atlas Glioblastoma Multiforme LACTB 0.25 0.04 enet 12 0.19 1.9e-06 4.9 -6.0 2.2e-09 -0.82 0.02 0.95 TRUE
11 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma LACTB 0.04 0.01 blup 52 0.02 2.5e-03 4.7 -5.4 7.5e-08 -0.85 0.02 0.94 FALSE
12 The Cancer Genome Atlas Brain Lower Grade Glioma LACTB 0.16 0.20 enet 8 0.21 2.5e-23 -5.4 -5.6 2.8e-08 -0.89 0.01 0.99 FALSE
13 The Cancer Genome Atlas Lung Adenocarcinoma LACTB 0.04 0.07 lasso 5 0.06 8.2e-08 -5.4 -5.6 2.0e-08 -0.89 0.01 0.99 FALSE
14 The Cancer Genome Atlas Lung Adenocarcinoma TPM1 0.05 0.04 blup 80 0.05 1.3e-06 3.2 -5.4 8.2e-08 -0.55 0.58 0.32 FALSE