[Hub]/) : Traits : Heel bone mineral density (BMD) T-score, automated (left) :

chr7:37,260,712-38,687,833

Best TWAS P=2.35e-27 · Best GWAS P=5.01e-41 conditioned to 0.177

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Visceral Omentum EPDR1 0.18 0.01 lasso 4 0.01 8.9e-02 7.9 6.5 7.7e-11 0.02 0.17 0.10 FALSE
2 GTEx Artery Tibial EPDR1 0.27 0.15 lasso 12 0.16 3.4e-12 7.9 6.5 7.2e-11 0.09 1.00 0.00 TRUE
3 GTEx Nerve Tibial EPDR1 0.29 0.14 lasso 4 0.23 2.7e-16 7.8 7.4 1.4e-13 0.10 1.00 0.00 FALSE
4 GTEx Pancreas EPDR1 0.18 0.15 lasso 5 0.17 1.0e-07 -9.6 9.7 2.9e-22 0.27 0.68 0.03 TRUE
5 GTEx Thyroid EPDR1 0.19 0.06 enet 25 0.10 4.0e-08 7.9 9.5 2.1e-21 0.24 0.67 0.21 TRUE
6 ROSMAP Brain Pre-frontal Cortex EPDR1 0.17 0.06 lasso 6 0.10 2.5e-13 4.6 7.2 6.2e-13 0.10 1.00 0.00 TRUE
7 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma EPDR1 0.08 0.04 enet 3 0.05 5.4e-06 7.9 10.8 2.4e-27 0.34 0.30 0.65 TRUE
8 The Cancer Genome Atlas Testicular Germ Cell Tumors EPDR1 0.09 0.10 lasso 2 0.06 2.8e-03 -5.5 5.7 1.0e-08 0.06 0.09 0.05 TRUE