[Hub]/) : Traits : Heel bone mineral density (BMD) T-score, automated (left) : ← →

chr7:37,260,712-38,687,833

Best TWAS P=2.35e-27 · Best GWAS P=5.01e-41 conditioned to 0.177

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
7	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	EPDR1	0.08	0.04	enet	3	0.05	5.4e-06	7.9	10.8	2.4e-27	0.34	0.30	0.65	TRUE
4	GTEx	Pancreas	EPDR1	0.18	0.15	lasso	5	0.17	1.0e-07	-9.6	9.7	2.9e-22	0.27	0.68	0.03	TRUE
5	GTEx	Thyroid	EPDR1	0.19	0.06	enet	25	0.10	4.0e-08	7.9	9.5	2.1e-21	0.24	0.67	0.21	TRUE
6	ROSMAP	Brain Pre-frontal Cortex	EPDR1	0.17	0.06	lasso	6	0.10	2.5e-13	4.6	7.2	6.2e-13	0.10	1.00	0.00	TRUE
2	GTEx	Artery Tibial	EPDR1	0.27	0.15	lasso	12	0.16	3.4e-12	7.9	6.5	7.2e-11	0.09	1.00	0.00	TRUE
8	The Cancer Genome Atlas	Testicular Germ Cell Tumors	EPDR1	0.09	0.10	lasso	2	0.06	2.8e-03	-5.5	5.7	1.0e-08	0.06	0.09	0.05	TRUE
3	GTEx	Nerve Tibial	EPDR1	0.29	0.14	lasso	4	0.23	2.7e-16	7.8	7.4	1.4e-13	0.10	1.00	0.00	FALSE
1	GTEx	Adipose Visceral Omentum	EPDR1	0.18	0.01	lasso	4	0.01	8.9e-02	7.9	6.5	7.7e-11	0.02	0.17	0.10	FALSE