Best TWAS P=2.91e-09 · Best GWAS P=3.59e-08 conditioned to 0.0105
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Adipose Visceral Omentum | GATAD1 | 0.12 | 0.08 | lasso | 5 | 0.06 | 7.5e-04 | -5.4 | 5.4 | 5.5e-08 | -0.58 | 0.03 | 0.96 | FALSE |
2 | GTEx | Adrenal Gland | GATAD1 | 0.40 | 0.22 | lasso | 7 | 0.25 | 2.0e-09 | -5.4 | 5.7 | 1.6e-08 | -0.63 | 0.01 | 0.99 | FALSE |
3 | GTEx | Artery Aorta | GATAD1 | 0.09 | 0.08 | enet | 4 | 0.07 | 7.4e-05 | -5.4 | 5.2 | 2.5e-07 | -0.56 | 0.02 | 0.97 | FALSE |
4 | GTEx | Artery Coronary | GATAD1 | 0.12 | 0.15 | lasso | 3 | 0.12 | 8.0e-05 | -4.9 | 5.3 | 1.2e-07 | -0.61 | 0.02 | 0.90 | FALSE |
5 | GTEx | Cells Transformed fibroblasts | GATAD1 | 0.23 | 0.20 | lasso | 4 | 0.22 | 1.4e-16 | -5.4 | 5.7 | 1.4e-08 | -0.72 | 0.00 | 1.00 | FALSE |
6 | GTEx | Colon Transverse | GATAD1 | 0.13 | 0.00 | enet | 16 | 0.05 | 3.0e-03 | -5.4 | 5.9 | 2.9e-09 | -0.58 | 0.02 | 0.90 | TRUE |
7 | GTEx | Esophagus Mucosa | GATAD1 | 0.16 | 0.05 | enet | 16 | 0.08 | 7.3e-06 | -5.4 | 5.2 | 2.2e-07 | -0.56 | 0.01 | 0.99 | FALSE |
8 | GTEx | Esophagus Muscularis | GATAD1 | 0.18 | 0.10 | enet | 33 | 0.13 | 1.6e-08 | -5.4 | 5.2 | 2.4e-07 | -0.46 | 0.02 | 0.98 | FALSE |
9 | GTEx | Lung | GATAD1 | 0.15 | 0.12 | lasso | 2 | 0.11 | 1.1e-08 | -5.4 | 5.4 | 8.1e-08 | -0.60 | 0.00 | 1.00 | FALSE |
10 | GTEx | Muscle Skeletal | GATAD1 | 0.05 | 0.00 | enet | 13 | 0.01 | 2.4e-02 | -3.7 | 5.3 | 1.2e-07 | -0.51 | 0.05 | 0.90 | FALSE |
11 | GTEx | Nerve Tibial | GATAD1 | 0.30 | 0.19 | lasso | 5 | 0.23 | 1.8e-16 | -5.4 | 5.3 | 1.3e-07 | -0.51 | 0.00 | 1.00 | FALSE |
12 | GTEx | Skin Not Sun Exposed Suprapubic | GATAD1 | 0.22 | 0.27 | lasso | 4 | 0.26 | 1.1e-14 | -5.4 | 5.3 | 9.0e-08 | -0.60 | 0.00 | 0.99 | FALSE |
13 | GTEx | Skin Sun Exposed Lower leg | GATAD1 | 0.30 | 0.10 | enet | 14 | 0.16 | 7.0e-13 | -5.4 | 5.3 | 9.3e-08 | -0.50 | 0.01 | 0.99 | FALSE |
14 | GTEx | Stomach | GATAD1 | 0.30 | 0.13 | lasso | 5 | 0.15 | 8.6e-08 | -5.4 | 5.3 | 1.2e-07 | -0.59 | 0.01 | 0.99 | FALSE |
15 | GTEx | Testis | CDK6 | 0.10 | 0.10 | lasso | 3 | 0.09 | 8.0e-05 | -5.1 | 5.4 | 6.1e-08 | -0.88 | 0.02 | 0.96 | FALSE |
16 | GTEx | Thyroid | GATAD1 | 0.18 | 0.06 | lasso | 4 | 0.06 | 3.3e-05 | -5.4 | 5.3 | 1.2e-07 | -0.55 | 0.01 | 0.99 | FALSE |