Best TWAS P=9.21e-10 · Best GWAS P=5.99e-08 conditioned to 0.101
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Esophagus Muscularis | PTPDC1 | 0.15 | 0 | lasso | 4 | 0.03 | 0.00609 | 4.6 | -5.7 | 1.1e-08 | -0.52 | 0.08 | 0.78 | FALSE |
2 | The Cancer Genome Atlas | Breast Invasive Carcinoma | BARX1 | 0.04 | 0 | blup | 66 | 0.01 | 0.00063 | 4.6 | -6.1 | 9.2e-10 | -0.69 | 0.01 | 0.82 | TRUE |