[Hub]/) : Traits : Heel bone mineral density (BMD) T-score, automated (left) : ← →

chr1:37,730,550-39,167,106

Best TWAS P=2.61e-09 · Best GWAS P=3.04e-08 conditioned to 0.234

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adrenal Gland FHL3 0.24 0.15 enet 17 0.34 7.4e-13 -4.3 -5.5 3.4e-08 -0.79 0.01 0.99 FALSE
2 GTEx Artery Aorta FHL3 0.35 0.22 lasso 4 0.27 3.9e-15 -4.3 -5.2 1.6e-07 -0.91 0.01 0.99 FALSE
3 GTEx Lung FHL3 0.14 0.07 enet 24 0.13 6.0e-10 -4.3 -5.3 9.0e-08 -0.83 0.02 0.98 FALSE
4 GTEx Pancreas FHL3 0.17 0.05 lasso 3 0.10 6.6e-05 5.5 -5.6 1.8e-08 -0.91 0.00 1.00 FALSE
5 GTEx Skin Sun Exposed Lower leg FHL3 0.15 0.09 lasso 5 0.10 1.2e-08 5.5 -5.1 2.7e-07 -0.91 0.00 1.00 FALSE
6 METSIM Adipose FHL3 0.15 0.12 lasso 5 0.14 6.3e-20 5.5 -5.7 1.1e-08 -0.93 0.00 1.00 FALSE
7 NTR Blood SF3A3 0.10 0.12 lasso 6 0.13 7.2e-39 5.5 5.2 2.4e-07 0.96 0.00 1.00 FALSE
8 The Cancer Genome Atlas Breast Invasive Carcinoma FHL3 0.06 0.01 enet 10 0.01 4.2e-04 5.5 -6.0 2.6e-09 -0.82 0.00 0.99 TRUE
9 The Cancer Genome Atlas Colon Adenocarcinoma FHL3 0.10 0.05 lasso 2 0.06 2.9e-04 -4.6 -5.3 9.1e-08 -0.92 0.00 0.97 FALSE
10 The Cancer Genome Atlas Lung Squamous Cell Carcinoma FHL3 0.08 0.08 lasso 2 0.08 1.4e-09 5.5 -5.5 4.9e-08 -0.99 0.00 1.00 FALSE
11 The Cancer Genome Atlas Stomach Adenocarcinoma FHL3 0.10 0.05 lasso 2 0.03 2.2e-03 5.5 -5.4 6.5e-08 -0.99 0.00 0.96 FALSE