[Hub]/) : Traits : Heel bone mineral density (BMD) T-score, automated (left) : ← →

chr13:49,557,805-51,390,447

Best TWAS P=2.4e-10 · Best GWAS P=2.33e-09 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Brain Cerebellum EBPL 0.50 0.30 enet 23 0.36 1.8e-11 -4.3 5.2 2.1e-07 -0.24 0.83 0.05 FALSE
2 GTEx Brain Frontal Cortex BA9 EBPL 0.50 0.20 enet 18 0.34 7.0e-10 -2.3 5.1 2.9e-07 -0.18 0.34 0.29 FALSE
3 GTEx Brain Nucleus accumbens basal ganglia EBPL 0.25 0.11 enet 21 0.11 7.9e-04 -4.2 5.4 6.4e-08 -0.26 0.11 0.22 FALSE
4 GTEx Brain Putamen basal ganglia EBPL 0.31 -0.01 enet 18 0.05 2.9e-02 -4.2 6.3 2.4e-10 -0.37 0.04 0.44 TRUE
5 GTEx Nerve Tibial DLEU2 0.11 0.05 lasso 3 0.02 7.8e-03 -5.8 -5.8 7.3e-09 0.98 0.01 0.98 TRUE
6 GTEx Thyroid EBPL 0.36 0.14 enet 33 0.30 5.1e-23 -4.2 5.7 9.3e-09 -0.31 0.97 0.03 FALSE
7 The Cancer Genome Atlas Colon Adenocarcinoma EBPL 0.20 0.04 blup 59 0.11 6.8e-07 3.9 5.1 2.9e-07 -0.20 0.02 0.67 FALSE
8 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma EBPL 0.21 0.14 enet 15 0.19 3.6e-21 3.9 5.4 5.4e-08 -0.18 0.02 0.79 FALSE
9 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma EBPL 0.27 0.16 blup 59 0.22 1.0e-12 3.9 5.9 4.4e-09 -0.24 0.02 0.78 TRUE
10 The Cancer Genome Atlas Lung Squamous Cell Carcinoma DLEU2 0.03 0.01 blup 61 0.02 2.4e-03 -5.7 -5.2 1.7e-07 0.91 0.01 0.96 TRUE
11 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma EBPL 0.28 0.18 blup 59 0.19 4.3e-08 -4.2 5.4 6.8e-08 -0.23 0.00 0.87 FALSE