TWAS
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Traits
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Heel bone mineral density (BMD) T-score, automated (left)
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chr1:239,954,252-241,470,634
Best TWAS P=5.51e-37 · Best GWAS P=5.24e-50 conditioned to 2.22e-16
240M
240.2M
240.4M
240.6M
240.8M
241M
241.2M
241.4M
0
10
20
30
40
50
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Cells Transformed fibroblasts
GREM2
0.29
0.13
enet
51
0.13
1.1e-09
15
13
5.5e-37
0.73
0
1
TRUE