Best TWAS P=9.09e-08 · Best GWAS P=1.72e-07 conditioned to 0.0249
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Colon Transverse | ABCB8 | 0.17 | 0.12 | lasso | 2 | 0.07 | 0.00048 | -5.0 | -5.3 | 1.2e-07 | 0.92 | 0.01 | 0.96 | FALSE |
2 | GTEx | Heart Atrial Appendage | ABCB8 | 0.13 | -0.01 | lasso | 4 | 0.02 | 0.04590 | 2.6 | -5.3 | 9.1e-08 | 0.67 | 0.02 | 0.87 | TRUE |