TWAS hub - ABCB8

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.2580	0.0450	3.1e-12	0.142	0.136	0.176	0.181	0.157	6.4e-17	3.3e-16	5.9e-21	1.4e-21	1.2e-18
2	GTEx	Artery Coronary	0.4690	0.0960	3.3e-04	0.196	NA	0.196	NA	0.197	3.4e-07	NA	3.5e-07	NA	3.3e-07
3	GTEx	Brain Cerebellum	0.2460	0.0840	8.6e-03	0.250	NA	0.138	NA	0.252	5.1e-08	NA	7.0e-05	NA	4.5e-08
4	GTEx	Colon Transverse	0.1700	0.0630	4.7e-03	0.124	NA	0.033	NA	0.065	1.7e-06	NA	1.0e-02	NA	4.8e-04
5	GTEx	Esophagus Mucosa	0.1460	0.0460	2.9e-04	0.101	NA	0.071	NA	0.075	3.0e-07	NA	1.6e-05	NA	1.0e-05
6	GTEx	Heart Atrial Appendage	0.1270	0.0540	8.2e-03	-0.006	NA	0.010	NA	0.019	7.8e-01	NA	1.1e-01	NA	4.6e-02
7	GTEx	Nerve Tibial	0.2264	0.0542	5.3e-06	0.018	NA	0.104	NA	0.093	1.7e-02	NA	8.7e-08	NA	4.3e-07
8	GTEx	Thyroid	0.1610	0.0550	9.6e-04	0.119	NA	0.142	NA	0.145	2.1e-09	NA	5.7e-11	NA	3.2e-11
9	TCGA	Brain Lower Grade Glioma	0.0304	0.0160	8.6e-03	0.012	0.009	0.009	NA	0.009	1.4e-02	3.1e-02	3.3e-02	NA	2.9e-02
10	TCGA	Lung Adenocarcinoma	0.0742	0.0295	5.8e-05	0.039	0.042	0.051	NA	0.027	2.1e-05	1.1e-05	1.2e-06	NA	3.6e-04
11	TCGA	Thyroid Carcinoma	0.0890	0.0290	1.2e-07	0.007	0.067	0.059	NA	0.034	5.8e-02	4.7e-07	1.9e-06	NA	2.9e-04

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11
Heel bone mineral density (BMD) T-score, automated (right)	8.0	18.3	28.5	-4.3	-2.3	-2.6	-5.3	-4.9	-5.3	-4.2	-4.4	-3.2	-4.2	-5.1
Heel bone mineral density (BMD) T-score, automated (left)	6.6	15.0	23.3	-3.9	-2.2	-2.5	-4.6	-4.4	-4.8	-3.8	-4.1	-3.1	-3.7	-4.5
Mean Putamen Volume	6.5	7.5	18.7	3.5	0.2	1.9	4.3	2.2	3.3	2.1	3.5	1.6	2.3	2.8
Serious illness, injury or assault of a close relative in last 2 years	6.4	7.3	12.3	-1.9	-2.6	-3.1	-1.7	-2.2	-3.5	-2.6	-2.5	-3.4	-2.9	-2.9
Maternal smoking around birth	5.9	8.6	14.8	3.9	2.3	2.6	3.0	2.4	3.5	2.3	3.5	3.0	2.3	2.9
Blood Red Count	5.7	54.6	97.6	6.1	4.5	4.5	9.9	9.2	9.1	8.3	6.5	4.2	7.3	8.8
Fractured/broken bones in last 5 years	5.7	7.4	13.9	2.9	1.3	1.6	3.4	1.7	3.1	3.3	3.2	2.2	2.2	3.7
Heel T-Score	4.4	35.3	65.1	-5.9	-2.2	-3.4	-7.8	-5.7	-8.1	-6.2	-6.1	-4.1	-5.4	-7.5
Chronotype (morning person)	4.3	9.9	16.3	2.7	3.6	2.2	2.8	3.5	3.4	3.3	2.3	2.1	4.0	4.0
Impedance of arm (left)	4.0	18.7	27.5	-3.4	-3.0	-3.6	-5.1	-4.6	-5.2	-4.4	-4.0	-3.2	-5.2	-5.0
Supplements: Glucosamine	3.8	4.9	10.4	-2.6	-0.4	-1.7	-3.2	-2.5	-2.5	-2.1	-2.5	-1.5	-1.4	-2.6
Length of working week for main job	3.8	4.2	11.0	1.2	0.9	1.1	3.0	3.3	2.3	2.3	2.0	1.3	2.0	1.4
Impedance of whole body	3.8	19.4	31.8	-3.5	-2.7	-3.2	-5.6	-4.7	-5.3	-4.1	-4.2	-2.9	-5.6	-5.3
Waist circumference	3.7	13.7	23.1	4.1	2.5	1.8	4.6	3.1	4.4	4.2	3.7	2.1	3.9	4.8
Medication: Amlodipine	3.7	5.2	10.7	3.3	2.6	1.6	1.2	0.9	2.3	2.1	1.9	1.9	2.7	3.2
Seen a psychiatrist for nerves, anxiety, tension or depression	3.6	4.7	10.1	3.2	0.9	3.0	0.9	-0.3	1.8	1.8	3.0	3.1	1.6	1.9
Mean time to correctly identify matches	3.5	6.7	11.4	-3.1	-0.6	-2.6	-2.7	-1.2	-2.5	-2.5	-3.2	-2.8	-2.5	-3.4
Waist Hip Ratio (WHR)	3.1	13.9	20.5	4.4	2.5	3.0	3.9	3.4	4.5	4.5	3.7	2.9	3.3	4.4
Hand grip strength (left)	3.1	8.0	14.9	3.9	0.6	2.6	3.4	2.5	3.0	2.6	3.5	2.2	2.7	3.0
Impedance of arm (right)	3.1	14.3	24.8	-2.8	-2.1	-3.2	-5.0	-4.4	-4.6	-3.5	-3.6	-2.7	-4.3	-4.4
Ever had stillbirth, spontaneous miscarriage or termination	3.1	3.3	6.6	-1.9	-1.8	-2.6	-0.8	-1.1	-1.7	-1.1	-2.0	-2.5	-2.4	-0.9
Chronic bronchitis/emphysema (father)	3.0	3.5	7.7	-2.3	-0.4	-1.5	-2.8	-1.5	-1.7	-2.4	-2.5	-1.3	-1.4	-1.7
Number of full brothers	2.8	3.5	6.5	-2.2	0.7	-1.9	-2.5	-1.4	-1.8	-1.8	-2.5	-1.7	-1.1	-2.1
Arm fat-free mass (left)	2.8	14.4	28.0	2.7	1.6	2.5	5.3	4.7	4.5	3.6	3.1	1.7	5.3	4.3
Arm predicted mass (left)	2.8	14.1	29.3	2.7	1.5	2.4	5.4	4.6	4.5	3.8	3.1	1.5	5.0	4.3
Lung FVC	2.7	13.6	30.9	3.2	2.2	5.6	2.0	2.2	3.5	1.5	4.1	5.1	5.3	2.9
Fed-up feelings	2.7	4.8	7.8	2.5	1.1	2.4	1.3	1.0	2.2	2.7	2.7	2.8	2.3	2.0
Reaction Time	2.6	4.9	6.8	-2.6	-0.8	-2.1	-2.4	-1.5	-2.4	-2.0	-2.6	-2.4	-2.3	-2.5
Average weekly fortified wine intake	2.6	3.0	6.5	-2.5	-1.3	-1.7	-0.9	-1.2	-1.5	-1.0	-1.7	-1.6	-2.6	-2.1
Medication: Ramipril	2.6	3.3	5.9	2.4	2.1	1.3	1.4	1.7	2.1	1.6	1.5	1.4	1.7	2.3
Arm predicted mass (right)	2.6	13.5	33.5	2.2	1.2	2.0	5.8	5.2	4.4	3.5	2.8	1.1	4.6	3.9
Basal metabolic rate	2.6	14.2	32.7	2.7	1.3	1.9	5.7	4.8	4.5	3.7	3.1	1.2	5.0	4.3
Depression (Nagel 2018)	2.5	3.7	7.2	2.2	1.4	1.4	2.0	1.4	2.4	1.7	2.1	1.8	1.6	2.7
Neuroticism	2.5	5.9	9.7	2.1	1.4	2.6	2.1	1.8	2.6	2.6	2.8	2.7	2.6	3.1
Qualifications: College or University degree	2.5	7.8	18.3	3.7	0.4	1.6	4.3	2.2	3.0	2.9	3.2	1.5	2.7	3.1
Whole body fat-free mass	2.5	14.4	35.0	2.4	1.1	2.0	5.9	5.1	4.5	3.6	3.0	1.1	5.1	4.1
Osteoporosis (self-reported)	2.5	3.1	5.4	1.3	1.7	0.8	2.0	1.8	2.3	1.7	1.8	1.5	2.0	1.9
HDL Cholesterol	2.4	4.0	13.8	-1.7	-0.7	-1.9	-2.2	-3.1	-2.5	-3.7	-1.7	0.0	0.0	0.0
Supplements: Zinc	2.4	2.6	5.2	-1.9	-1.2	-1.4	-1.3	-1.1	-2.1	-1.4	-1.4	-1.5	-1.6	-2.3
Impedance of leg (right)	2.4	11.6	27.5	-2.2	-1.4	-1.9	-5.2	-4.0	-4.0	-2.8	-3.0	-1.4	-4.4	-4.5
Body mass index (BMI)	2.4	10.4	19.3	3.5	2.6	1.8	3.4	2.1	3.7	3.6	3.5	2.4	3.5	4.4
Impedance of leg (left)	2.4	11.8	25.9	-2.5	-1.6	-1.6	-5.1	-3.9	-4.2	-2.9	-2.9	-1.4	-4.5	-4.5
Leg predicted mass (left)	2.4	12.5	31.4	2.7	1.1	1.3	5.6	4.4	4.1	3.3	2.9	0.8	4.5	4.3
Trunk fat-free mass	2.4	14.0	32.5	2.2	1.0	2.4	5.7	5.2	4.4	3.5	2.8	1.2	5.2	3.7
Trunk predicted mass	2.4	13.8	32.0	2.1	0.9	2.4	5.7	5.2	4.4	3.5	2.8	1.2	5.2	3.7
Arm fat-free mass (right)	2.4	12.4	32.1	1.9	1.1	1.7	5.7	5.0	4.2	3.4	2.6	0.8	4.5	3.8
Leg fat-free mass (right)	2.4	12.6	33.9	2.5	0.9	1.6	5.8	4.6	4.1	3.2	3.0	0.8	4.6	4.2
Whole body water mass	2.4	13.9	34.3	2.3	1.1	1.9	5.9	5.2	4.4	3.5	2.8	1.0	5.0	4.0
Depressed Affect (Nagel 2018)	2.3	4.8	7.1	2.1	2.0	2.3	1.1	1.2	2.5	2.7	2.3	2.6	1.9	2.6
Leg fat-free mass (left)	2.3	12.1	30.7	2.6	1.1	1.2	5.5	4.3	4.1	3.2	2.8	0.7	4.5	4.3
Birth weight of first child	2.3	4.1	11.3	1.2	0.8	2.5	1.2	1.8	2.3	1.7	1.4	2.1	3.4	2.5
Commuting to job workplace: Car/motor vehicle	2.3	2.7	3.8	1.6	1.8	1.7	0.8	1.5	1.8	2.0	1.1	1.5	1.9	1.8
Leg predicted mass (right)	2.3	12.4	33.3	2.5	0.9	1.5	5.8	4.5	4.0	3.2	3.0	0.8	4.5	4.2
Had menopause	2.2	2.7	6.0	-1.4	-0.1	-1.1	-2.1	-1.6	-1.8	-2.4	-1.8	-1.3	-1.4	-1.8
Coronary Artery Disease (CAD)	2.1	2.5	6.7	2.6	1.9	0.6	1.6	1.5	1.4	2.6	1.9	0.0	0.0	0.0
BMI	2.1	12.2	26.7	3.5	2.6	1.8	3.3	2.5	3.9	4.4	3.3	2.4	4.1	5.2
Frequency of unenthusiasm / disinterest in last 2 weeks	2.1	2.9	4.7	1.4	1.8	0.6	1.7	1.6	2.1	2.1	1.7	1.4	2.2	1.5
Leg fat mass (right)	2.1	8.0	13.2	3.4	2.1	1.2	3.2	1.9	3.3	3.3	3.0	1.9	2.9	3.6
Hearing difficulty/problems: Yes	2.0	3.0	6.8	-2.0	0.7	-2.6	-1.9	-0.1	-1.8	-0.9	-2.6	-2.2	-1.4	-1.0
Tinnitus: Yes, but not now, but have in the past	2.0	2.1	5.0	1.3	0.0	1.8	0.6	0.1	1.4	0.4	2.0	2.2	2.1	1.6
Weight	2.0	9.8	18.1	2.8	1.5	1.2	4.3	3.5	3.6	3.3	2.7	1.2	4.1	4.1
Arm fat mass (right)	2.0	8.2	14.3	3.0	2.0	1.2	3.2	2.0	3.4	3.3	2.9	1.9	3.5	3.8
Age at first live birth	2.0	3.5	10.2	1.6	1.4	1.5	0.8	1.2	2.2	3.2	1.6	2.2	1.6	2.3
Migraine (self-reported)	2.0	2.5	6.8	-0.9	-2.6	-1.8	0.1	-1.5	-1.8	-1.3	-0.9	-2.3	-1.8	-0.6
Ever depressed for a whole week	2.0	2.5	6.7	-0.1	-1.5	-1.1	-0.8	-1.8	-2.0	-2.6	-0.7	-1.7	-2.2	-1.0
Leg fat mass (left)	2.0	7.7	12.5	3.2	2.0	1.4	3.1	1.9	3.2	3.3	3.0	2.0	2.9	3.5
Hand grip strength (right)	1.9	5.1	10.3	2.7	0.3	1.7	3.2	3.0	2.5	2.1	2.3	1.0	1.7	2.7
Qualifications: nursing, teaching	1.9	2.9	5.0	1.9	0.5	2.2	1.6	0.8	1.9	0.6	2.1	2.1	1.7	2.0
Frequency of depressed mood in last 2 weeks	1.8	2.6	4.7	1.5	1.0	1.8	1.1	0.7	1.7	1.5	2.2	2.2	1.3	2.0
Qualifications: None of the above	1.8	3.8	13.0	-2.9	1.3	-0.3	-3.6	-1.4	-1.9	-1.1	-2.5	-0.4	-1.1	-2.1
Average weekly red wine intake	1.8	2.7	5.4	-1.2	-0.8	-1.8	-0.7	-1.0	-1.7	-2.0	-1.6	-2.0	-2.0	-2.3
Mouth/teeth dental problems: Mouth ulcers	1.8	2.8	6.1	0.8	1.8	0.2	1.7	2.5	2.0	1.8	1.1	1.1	1.9	2.1
Risk taking	1.8	2.6	6.5	2.5	0.8	1.8	1.4	0.2	1.1	1.3	2.3	1.7	1.6	1.8
Breast Cancer	1.7	4.1	8.1	2.3	-0.4	1.7	2.9	1.9	2.1	2.1	2.6	1.3	1.7	2.1
Ever highly irritable/argumentative for 2 days	1.7	2.1	4.5	1.8	0.2	1.2	1.8	0.1	1.1	1.7	2.1	1.3	0.9	2.0
Forced vital capacity (FVC), Best measure	1.7	6.3	15.6	1.9	0.6	3.1	2.8	2.6	2.9	1.5	2.4	2.2	4.0	2.2
Arm fat mass (left)	1.7	6.9	12.0	2.8	1.7	1.1	3.1	1.9	3.1	3.0	2.8	1.7	3.2	3.5
Bipolar Disorder or Schizophrenia	1.6	3.8	9.0	-1.5	1.7	-1.9	-2.2	-0.1	-1.7	-2.0	-3.0	-2.1	-1.4	-2.5
Average weekly spirits intake	1.6	2.0	8.0	-1.1	-1.1	-1.5	-0.4	-0.9	-1.5	-1.4	-0.6	-1.3	-1.3	-2.8
Hip circumference	1.6	6.7	13.2	2.5	2.0	0.9	3.6	2.6	3.0	3.0	2.3	1.1	2.9	3.1
Forced expiratory volume in 1-second (FEV1)	1.6	5.3	11.4	1.2	0.2	2.5	3.4	3.3	2.5	1.8	1.9	1.4	3.2	1.7
Medication: Ibuprofen (e.g. Nurofen)	1.6	2.1	4.9	1.5	0.9	0.5	1.7	1.3	1.7	1.7	1.2	0.5	1.5	2.2
Illnesses of father: None of the above (group 1)	1.6	2.0	4.9	1.5	0.6	0.2	2.2	2.1	1.7	1.6	1.2	0.3	1.2	0.9
Neuroticism (Nagel 2018)	1.5	3.5	5.9	1.7	1.4	2.1	1.1	1.0	1.9	2.3	2.2	2.2	1.6	2.4
Medication for hormone replacement therapy	1.5	1.7	4.1	-1.6	-0.5	-2.0	-0.7	0.0	-1.4	-0.3	-1.9	-1.9	-0.8	-1.2
Forced expiratory volume in 1-second (FEV1), Best measure	1.5	4.8	9.8	1.4	0.0	2.1	3.1	2.9	2.7	1.6	1.8	1.4	3.1	1.8
Comparative body size at age 10	1.5	4.0	10.6	1.7	1.7	1.3	3.3	2.9	2.0	1.8	2.1	1.1	1.7	1.6
Supplements: Vitamin C	1.5	1.8	3.5	-1.2	0.2	-1.3	-1.6	-1.3	-1.6	-1.9	-1.7	-1.3	-1.2	-0.6
Osteoarthritis (self-reported)	1.5	2.0	5.7	-1.4	-0.4	-2.3	-0.8	-0.6	-1.1	-0.4	-1.9	-2.4	-1.4	-0.8
Alcohol drinker status: Never	1.5	1.8	7.7	0.0	-2.8	-0.3	-0.0	-1.6	-1.3	-2.7	-0.1	-0.8	-0.3	-0.3
Age at First Birth	1.4	2.1	4.7	-0.8	-1.0	-1.1	-1.7	-2.0	-1.5	-1.4	-1.2	-1.2	-2.2	-1.2
Allergy or Eczema	1.4	3.7	10.6	-3.3	-2.0	-2.8	0.5	1.2	-0.4	0.5	-2.7	-2.6	-0.6	-1.4
Medication: Co-codamol	1.4	1.6	3.9	1.2	0.3	0.4	2.0	0.8	1.8	1.5	1.7	0.6	1.4	0.7
Ever unenthusiastic/disinterested for a whole week	1.4	1.8	6.0	0.9	-1.3	1.0	-0.8	-2.4	-1.0	-2.0	1.1	0.8	-1.1	-1.0
Miserableness	1.4	2.4	4.6	1.3	1.3	1.5	1.0	0.2	1.8	2.2	1.7	2.0	0.9	2.0
Bilateral oophorectomy (both ovaries removed)	1.3	1.5	5.3	-1.1	-1.0	-2.3	1.2	0.1	-0.6	-0.6	-0.3	-1.9	-1.0	-1.6
Medication: Atenolol	1.3	1.6	3.6	-0.8	-0.6	-1.2	-1.1	-1.6	-1.4	-1.4	-1.0	-1.4	-1.9	-1.2
Hearing difficulty/problems with background noise	1.3	2.1	4.9	-1.6	1.7	-1.7	-2.1	-0.3	-1.2	-0.8	-2.2	-1.4	-0.6	-0.7
Heart attack	1.3	1.7	5.4	-0.5	-2.3	-1.2	0.2	-1.0	-1.4	-2.0	-0.3	-1.5	-1.0	-1.0
Blood clot in the leg (DVT)	1.3	1.6	4.5	-0.8	-0.8	-1.3	-1.4	-1.6	-1.3	-2.1	-0.9	-0.8	-1.6	-0.7
Whole body fat mass	1.3	5.6	9.0	2.5	1.9	0.7	2.7	2.1	2.8	2.9	2.2	1.3	2.8	3.0
Mood swings	1.3	2.4	5.0	0.6	1.5	1.3	1.4	1.5	1.7	2.2	1.3	1.5	1.5	1.9
Mineral and other dietary supplements	1.3	1.8	4.6	1.9	-1.3	1.2	2.0	0.0	1.2	0.7	2.1	1.0	-0.0	1.2
Townsend deprivation index at recruitment	1.2	1.7	3.6	-1.3	-1.4	-0.8	-1.5	-1.9	-1.7	-0.8	-0.8	-0.9	-1.3	-1.3
Forced vital capacity (FVC)	1.2	4.7	12.6	1.1	0.4	2.9	2.7	2.9	2.1	1.2	1.8	1.8	3.5	1.3
Loud music exposure frequency	1.2	1.3	6.3	-1.2	-2.5	-0.1	-0.8	-1.2	-1.3	-1.0	-0.4	-0.3	-0.8	-0.8
Headache pain in last month	1.2	2.0	3.5	-1.5	-1.1	-1.4	-1.2	-1.6	-1.8	-0.9	-1.5	-1.5	-1.9	-1.0
Leg pain on walking	1.2	1.5	3.0	-1.4	0.2	-1.7	-1.2	-0.7	-1.2	-1.3	-1.6	-1.6	-0.4	-0.9
High cholesterol (Self-reported)	1.2	2.1	5.1	-0.1	-0.4	-1.2	-0.7	-2.3	-2.1	-1.8	-0.1	-1.3	-1.6	-1.9
Heart attack/myocardial infarction (self-reported)	1.2	1.5	5.0	-0.4	-2.2	-1.1	0.3	-0.9	-1.3	-1.8	-0.2	-1.5	-1.0	-1.0
Bipolar Disorder (2018)	1.1	1.7	3.3	-1.4	0.5	-1.6	-1.1	-0.0	-1.3	-1.2	-1.8	-1.7	-0.6	-1.8
Schizophrenia (2018)	1.1	2.3	5.6	-0.8	1.8	-1.1	-2.0	-0.1	-1.1	-1.6	-2.4	-1.4	-1.3	-1.7
Schizophrenia (2014)	1.1	2.5	5.8	-1.3	2.0	-1.3	-1.7	0.1	-1.2	-1.3	-2.4	-1.6	-0.9	-2.1
Diabetes (father)	1.1	1.3	3.6	1.0	-0.7	1.1	1.3	0.7	1.5	0.2	1.1	1.1	1.2	1.9
Medication: Levothyroxine sodium	1.1	1.9	6.9	-0.1	1.8	-0.3	1.0	2.6	1.6	1.9	0.2	0.7	1.3	0.6
High blood pressure (mother)	1.1	1.5	2.5	1.5	1.3	0.5	1.0	1.2	1.3	1.6	1.4	1.0	1.4	0.8
Neuroticism score	1.1	2.3	4.8	0.9	1.2	1.6	0.8	1.0	1.6	2.2	1.4	1.7	1.7	2.0
Breastfed as a baby	1.1	1.4	2.7	-1.2	-0.7	-0.9	-1.5	-0.3	-1.4	-1.4	-1.6	-1.2	0.2	-1.5
Leg fat percentage (right)	1.1	3.9	9.1	3.0	2.0	0.9	1.3	0.3	2.2	2.4	2.4	2.0	1.4	2.3
Worry too long after embarrassment	1.1	1.8	3.6	0.4	0.5	1.4	1.9	1.8	1.4	1.4	1.6	1.1	0.7	1.6
Wheeze or whistling in the chest in last year	1.1	1.9	3.4	0.6	1.4	0.6	1.8	1.4	1.7	1.8	1.2	1.0	1.7	1.3
Loneliness, isolation	1.1	1.5	3.4	0.8	1.6	0.7	1.0	1.2	1.6	1.8	0.5	0.8	1.2	1.5
Smoking status: Current	1.1	1.8	4.9	-2.1	-0.1	-1.6	-1.0	0.1	-1.5	-0.2	-1.3	-1.1	-1.1	-2.2
Leg fat percentage (left)	1.1	3.9	8.2	2.9	1.9	1.2	1.4	0.3	2.1	2.3	2.5	2.1	1.4	2.3
Rheumatoid Arthritis	1.0	1.4	3.2	1.0	1.6	1.4	-0.8	-0.1	0.8	0.6	0.8	1.8	1.1	1.6
Triglycerides	1.0	1.7	7.0	1.0	1.3	1.0	1.4	1.9	1.3	2.6	0.8	0.0	0.0	0.0
Ever used hormone-replacement therapy (HRT)	1.0	1.2	2.7	-1.0	-0.6	-1.3	-0.3	-0.1	-1.6	-1.2	-0.7	-1.3	-1.1	-1.6
Vitamin and mineral supplements	1.0	1.4	4.1	1.3	-2.0	0.8	1.8	0.1	0.8	0.3	2.0	0.8	0.4	-0.1
Peak expiratory flow (PEF)	1.0	2.3	7.4	1.4	-0.6	1.2	2.7	1.8	1.6	1.3	1.4	0.7	1.4	1.4
Qualifications: O levels/GCSEs or equivalent	1.0	1.6	3.6	-0.2	-1.9	-1.4	-0.2	-1.3	-1.3	-1.6	-0.5	-1.4	-1.1	-1.5
Exposure to tobacco smoke outside home	1.0	1.3	4.1	0.7	2.0	0.6	0.3	2.0	1.1	1.6	0.2	0.9	0.7	0.5
Medication for pain relief, constipation, heartburn	1.0	1.8	4.7	-2.0	-0.2	0.1	-2.2	-1.0	-1.4	-0.8	-1.7	-0.2	-1.6	-1.2
Medication: Allopurinol	1.0	1.3	2.7	-1.2	-1.3	-1.3	0.2	-0.8	-1.2	-1.0	-0.6	-1.3	-1.6	-1.0
Number of full sisters	1.0	1.2	3.1	-0.7	-0.3	-1.0	-1.1	-1.3	-1.5	-1.8	-0.8	-1.0	-1.2	-0.6
Medication: Aspirin	1.0	1.4	5.6	1.2	-1.4	-1.0	0.1	-1.4	-1.1	-2.4	0.5	-0.9	-0.6	-0.6
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.0	2.1	4.6	0.7	1.2	2.0	1.2	1.0	1.7	0.8	1.1	1.5	2.1	1.8
Average weekly champagne plus white wine intake	1.0	1.4	2.7	1.4	1.1	1.1	0.5	0.4	1.0	1.6	1.0	1.1	1.6	1.5
Sensitivity / hurt feelings	0.9	1.6	3.6	1.1	-0.6	1.9	0.9	0.1	1.0	0.9	1.9	1.8	1.0	1.3
Severe depression (siblings)	0.9	1.0	2.0	-1.3	-1.1	-1.3	-1.1	-0.4	-1.1	-0.3	-1.3	-1.4	-0.4	-0.2
Hayfever, allergic rhinitis or eczema	0.9	1.8	6.2	-2.5	-1.2	-2.0	0.3	0.7	0.0	0.7	-2.1	-1.7	0.1	-0.8
Multivitamins +/- minerals	0.9	1.1	3.2	-1.6	1.8	-0.7	-1.3	1.0	-0.2	0.3	-1.8	-0.5	-0.0	-0.4
Depression (self-reported)	0.9	1.1	3.8	-0.8	-0.4	0.4	-1.9	-1.8	-1.1	-1.1	-0.5	0.4	-0.4	-0.9
Medication: Ibuprofen	0.9	1.1	3.7	0.4	1.5	0.5	0.3	1.1	1.3	1.2	-0.1	0.3	1.3	1.9
Family relationship satisfaction	0.9	1.2	2.8	1.1	1.2	1.5	0.1	0.3	1.6	0.2	1.2	1.7	0.4	0.9
Illness, injury, bereavement, stress in last 2 years	0.9	1.0	3.7	-1.9	0.1	0.1	-1.3	0.2	-0.9	-1.0	-1.2	-0.0	0.1	-1.6
Diastolic blood pressure, automated reading	0.9	2.7	12.5	3.5	1.7	1.1	0.2	-0.8	1.1	1.6	1.9	1.3	0.6	1.8
Basal cell carcinoma (self-reported)	0.9	1.0	3.1	-1.6	-0.6	-0.3	-1.8	-0.2	-1.0	-0.4	-1.7	-1.0	0.1	-0.5
Deep venous thrombosis (DVT) (self-reported)	0.9	1.1	3.1	-0.6	-0.7	-0.9	-1.2	-1.3	-1.0	-1.8	-0.7	-0.5	-1.4	-0.5
Alzheimer’s Disease (in mother)	0.8	1.0	2.6	-0.1	-1.6	-0.7	-0.9	-0.9	-1.6	-1.2	-0.4	-0.6	-1.2	-0.4
Number of treatments/medications taken	0.8	1.4	3.6	1.5	1.9	-0.2	0.7	1.2	1.3	1.6	0.2	0.1	1.0	1.4
Ever had hysterectomy (womb removed)	0.8	0.9	3.8	-0.4	-0.3	-0.8	0.9	0.6	-0.8	-0.5	0.5	-0.6	-1.6	-1.9
Current tobacco smoking	0.8	1.4	3.6	-1.9	-0.2	-1.5	-0.7	0.4	-1.3	-0.1	-1.2	-1.1	-0.9	-1.9
Arm fat percentage (right)	0.8	3.3	5.9	2.4	1.5	0.6	1.4	0.3	2.0	2.0	2.2	1.7	1.9	2.4
Time employed in main current job	0.8	0.9	3.7	0.2	-1.4	-0.8	1.6	1.9	0.8	0.3	-0.2	-0.8	0.3	0.2
Medication: Cholesterol lowering	0.8	1.3	4.4	1.5	-1.0	-0.5	0.0	-2.1	-1.2	-1.5	1.0	-0.5	-1.1	-0.4
Medication: Ventolin 100micrograms inhaler	0.8	1.0	4.2	1.1	-1.2	0.1	2.0	0.3	1.1	0.4	1.4	0.4	0.7	0.8
Birth weight	0.8	1.6	4.8	-1.5	-1.0	-0.8	-1.3	-0.9	-1.3	-2.2	-1.3	-1.0	-1.0	-1.3
Had major operations	0.8	0.9	2.3	-0.9	0.2	-1.4	-1.0	-0.7	-0.6	-1.5	-1.2	-0.9	0.1	-1.0
Medication: Bendroflumethiazide	0.8	1.3	3.4	1.2	1.6	-0.1	1.5	1.4	1.1	1.8	0.6	0.0	0.3	0.9
Supplements: Calcium	0.8	0.9	3.2	-0.1	1.1	0.7	-0.8	0.8	1.2	0.3	-0.2	1.0	1.8	1.0
Bipolar Disorder (2011)	0.7	0.7	2.0	-0.3	-1.3	-0.1	-1.0	-1.2	-1.4	-0.9	-0.6	0.0	0.0	0.0
Primary Biliary Cirrhosis	0.7	1.1	2.3	-0.8	0.1	-0.8	-1.4	-1.2	-1.2	-1.5	-0.9	-0.4	0.2	-1.5
Type 2 Diabetes (T2D) (2012)	0.7	0.9	3.3	0.0	1.8	-0.7	0.7	1.6	0.7	1.3	-0.5	0.0	0.0	0.0
Ulcerative Colitis	0.7	1.1	4.0	-2.0	-1.1	-0.1	-1.0	-1.2	-1.2	-0.8	-1.1	-0.5	-0.7	0.3
Blood White Count	0.7	5.0	8.5	2.9	1.7	1.6	2.3	2.5	2.4	2.2	2.6	1.7	2.2	2.2
Cardiovascular Disease	0.7	2.2	11.2	3.3	1.7	0.2	0.9	-0.5	0.3	1.3	1.9	0.2	-0.0	2.1
Relative age of first facial hair	0.7	1.5	4.4	0.2	-1.4	-0.3	2.1	1.8	1.3	1.2	0.8	0.4	1.0	1.2
Angina	0.7	0.9	1.6	-0.4	-1.2	-1.2	0.1	-0.7	-1.1	-0.9	-0.0	-1.3	-1.2	-1.1
Sitting height	0.7	5.0	12.5	-3.1	-2.4	-1.7	1.2	2.3	-1.5	-1.7	-2.5	-3.5	-0.5	-2.4
Trunk fat mass	0.7	2.8	5.2	1.6	1.1	-0.0	2.2	1.8	2.0	2.0	1.4	0.5	1.9	2.3
Had other major operations	0.7	0.9	1.7	1.0	0.1	1.0	0.5	-0.6	0.7	0.6	1.3	1.1	1.3	1.2
Financial difficulties in last 2 years	0.7	1.0	2.9	1.3	-0.4	0.6	1.0	0.2	0.9	0.9	1.5	0.9	0.4	1.7
Mouth/teeth dental problems	0.7	1.1	5.0	1.1	-0.0	2.2	0.2	-0.9	0.3	-0.3	1.6	1.5	0.4	0.5
Frequency of tiredness / lethargy in last 2 weeks	0.7	1.1	3.4	0.4	0.6	-0.4	0.1	0.4	1.5	1.9	0.3	0.5	1.5	1.9
Hair/balding pattern: Pattern 3	0.7	1.0	3.2	0.6	1.8	1.1	-1.1	-0.4	0.4	-0.3	0.3	1.4	1.0	1.4
Gout (self-reported)	0.7	0.9	3.5	-0.8	-1.9	-0.8	0.5	-1.0	-0.9	-0.8	0.0	-0.8	-1.2	-0.3
High blood pressure (siblings)	0.7	1.0	4.1	0.3	2.0	0.8	0.1	1.2	0.5	1.7	0.4	0.6	1.0	0.6
Shortness of breath walking on level ground	0.7	0.8	2.2	1.5	0.4	0.6	0.5	-0.8	0.8	0.1	1.2	0.7	0.6	1.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.7	0.8	2.2	-1.1	0.6	-1.4	-0.3	0.2	-0.0	0.2	-1.5	-1.4	-0.1	0.6
Arm fat percentage (left)	0.7	2.7	5.8	2.3	1.2	0.3	1.6	0.3	1.9	1.9	2.1	1.3	1.4	2.4
Back pain experienced in last month	0.7	1.0	2.8	-1.2	1.4	-0.8	-1.2	0.6	0.0	-0.5	-1.5	-0.5	1.7	-0.5
Medication: Atorvastatin	0.7	0.9	3.5	1.9	1.0	0.8	0.2	-0.2	0.3	0.3	1.5	1.1	0.4	0.9
Unable to work because of sickness or disability	0.7	0.9	2.5	-0.3	1.1	-1.1	-1.6	-1.4	-0.1	-0.8	-1.0	-0.8	-0.5	-0.1
Verbal and Numeric Reasoning (VNR)	0.6	1.4	3.4	1.2	-1.1	0.8	1.2	1.3	1.0	0.8	1.2	0.9	1.2	1.8
Fasting Glucose	0.6	0.7	3.0	-0.1	1.4	-0.6	0.1	1.7	0.6	0.6	-0.9	-0.6	0.7	0.2
Eye problems/disorders: Diabetes related eye disease	0.6	0.7	1.8	-0.4	1.3	-1.3	-1.0	0.0	-0.0	-0.5	-1.1	-0.8	0.7	0.4
High blood pressure	0.6	1.6	8.0	2.8	1.4	0.4	0.2	-0.5	0.5	1.1	1.2	0.6	0.5	1.9
Stomach or abdominal pain in last month	0.6	0.8	2.0	0.6	-0.3	-0.7	1.2	0.3	0.9	1.2	0.8	-0.0	1.4	1.0
Diverticular disease/diverticulitis (self-reported)	0.6	0.8	2.5	1.3	-0.8	0.4	1.6	0.4	0.9	1.0	1.2	0.5	0.3	0.0
Mouth/teeth dental problems: Dentures	0.6	1.0	3.6	-1.1	0.0	-1.9	-0.5	-0.1	-0.7	-0.2	-1.4	-1.3	-0.4	-1.3
Illnesses of mother	0.6	0.7	2.6	-1.6	-1.1	-0.2	0.1	-0.3	-0.6	-0.8	-0.6	-0.7	-1.2	-0.8
Pulse wave Arterial Stiffness index	0.6	0.7	1.8	-0.7	0.2	-0.9	0.2	0.7	-0.5	-0.9	-1.3	-1.3	-1.1	-0.2
Medication for cholesterol, blood pressure or diabetes	0.6	1.0	3.7	-1.9	0.6	0.4	0.1	1.4	1.1	0.8	-1.1	0.2	1.2	0.3
Chronic bronchitis/emphysema (mother)	0.6	0.7	2.4	0.5	-0.9	-0.5	-0.6	-1.5	-0.3	-1.5	0.1	-0.2	0.9	-0.6
Comparative height size at age 10	0.6	3.1	12.5	-2.0	-1.0	-1.3	0.8	3.5	0.0	-0.5	-2.5	-2.5	1.1	-0.8
Illnesses of siblings: Diabetes	0.6	0.8	5.1	0.0	2.2	0.4	0.1	1.3	0.7	0.6	-0.3	0.3	0.6	0.7
Eye problems/disorders: Cataract	0.6	0.7	2.1	0.2	0.5	0.2	1.4	1.3	0.9	1.2	0.2	-0.1	0.9	0.3
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.6	0.7	2.7	-0.1	1.6	-0.6	1.4	0.8	0.6	0.9	0.3	-0.6	0.6	-0.3
Asthma (self-reported)	0.6	1.3	4.7	1.1	1.1	-0.1	1.4	0.7	1.3	2.2	0.4	0.1	0.7	1.4
Medication: Aspirin	0.6	0.7	3.1	1.5	-0.8	-0.4	0.4	-0.8	-0.5	-1.8	0.8	-0.4	-0.1	-0.2
Ever smoked	0.6	1.0	2.2	-1.1	-0.9	-0.5	-1.5	-0.6	-1.1	-0.8	-1.2	-0.4	-1.3	-0.9
Number of operations (self-reported)	0.6	0.8	2.9	-1.3	-0.4	-1.7	-0.3	-0.4	-0.6	-0.3	-1.0	-1.3	0.4	-0.9
Irritability	0.6	1.1	4.1	-0.3	2.0	-1.1	-1.2	-0.0	-0.2	0.8	-1.1	-0.7	0.9	1.4
Commuting to job workplace: Cycle	0.6	0.7	2.5	0.3	0.4	0.2	1.6	1.2	1.0	1.0	0.8	0.6	0.7	0.7
Medication: Omeprazole (e.g. Zanprol)	0.6	0.8	1.7	-0.0	-0.7	-0.9	1.3	1.1	0.4	1.0	0.1	-0.8	1.3	0.9
Prostate Cancer	0.5	0.7	4.9	0.2	2.2	0.5	-0.8	-0.2	0.0	-0.2	-0.0	0.4	1.3	0.6
Relative age voice broke	0.5	0.7	2.9	-0.3	-1.1	-0.7	1.6	1.7	0.5	0.5	0.4	-0.3	-0.1	-0.1
Qualifications: CSEs or equivalent	0.5	0.6	1.3	-1.1	-1.1	-1.0	-0.7	0.1	-0.4	0.8	-0.4	-0.2	-1.0	-0.8
Medication: Simvastatin	0.5	0.8	1.8	0.0	-0.8	-0.7	-0.4	-1.2	-1.3	-1.0	-0.0	-0.9	-1.3	-0.5
Illnesses of siblings	0.5	0.7	3.9	0.6	-1.1	-0.3	-0.7	-2.0	-0.2	-1.1	0.2	0.3	-0.4	0.4
Worrier / anxious feelings	0.5	0.9	2.6	0.9	0.2	1.4	-0.2	-0.1	0.4	0.6	0.6	1.1	1.4	1.6
Asthma	0.5	1.1	4.7	0.9	0.9	-0.3	1.2	0.5	1.1	2.2	0.3	0.0	0.6	1.4
Prospective memory result	0.5	0.6	2.3	0.6	1.1	0.7	1.2	0.5	0.5	0.3	0.5	0.1	-0.1	1.5
Seen doctor (GP) for nerves, anxiety, tension or depression	0.5	0.8	2.7	0.7	-0.5	0.9	-1.3	-1.7	-0.7	-1.0	0.5	0.8	-0.5	-0.3
Pulse wave reflection index	0.5	0.6	1.8	-0.7	-0.0	-0.9	0.6	1.4	0.3	-0.1	-0.8	-0.8	-0.6	1.4
Hypothyroidism/myxoedema (self-reported)	0.5	0.9	3.0	-0.2	1.6	-0.9	0.3	1.5	0.6	1.7	-0.4	0.0	0.7	0.4
Eye problems/disorders: None of the above	0.5	0.6	2.5	0.9	-0.3	0.8	-0.3	-1.6	-0.3	-0.5	0.9	0.8	-0.5	0.1
Mouth/teeth dental problems: Loose teeth	0.5	0.6	2.0	0.7	-0.8	0.4	-0.4	-0.7	0.1	1.4	0.7	0.9	0.7	0.7
Medication: Blood pressure	0.5	0.9	5.9	2.4	0.3	0.3	0.8	0.1	0.4	0.5	1.2	0.3	-0.3	1.0
Angina (self-reported)	0.5	0.7	1.6	0.1	-1.3	-1.0	0.4	-0.7	-0.8	-0.8	0.4	-1.0	-1.1	-0.8
Chest pain or discomfort	0.5	0.7	1.6	-0.4	-0.8	-1.3	-0.4	-1.3	-1.1	-0.9	-0.3	-0.8	-0.3	-0.7
Hypertension (Self-reported)	0.5	1.4	7.2	2.7	1.7	0.3	-0.0	-0.5	0.4	0.9	1.0	0.4	0.3	1.8
Illnesses of father: Heart disease	0.5	0.7	2.6	-0.2	-0.7	-0.3	-0.9	-1.6	-1.1	-0.6	-0.1	0.1	-1.3	-0.8
Ever had bowel cancer screening	0.5	0.6	2.9	0.3	-0.9	0.4	0.4	-0.2	0.0	-1.7	0.7	0.6	0.9	-1.0
Medication for cholesterol	0.5	0.8	2.3	0.4	-1.2	1.5	-0.1	-0.4	0.6	-0.7	0.7	1.3	1.2	0.4
Breast cancer (self-reported)	0.5	0.5	2.1	0.0	0.8	-0.2	-1.3	-1.5	-0.9	-0.3	-0.5	-0.1	-0.2	-0.6
Medication: Gliclazide	0.5	0.6	1.5	1.2	0.4	1.2	-0.4	-0.7	-0.0	-0.5	1.1	1.2	0.6	0.1
Eye problems/disorders: Glaucoma	0.5	0.5	1.4	-1.0	-0.3	-0.6	-0.3	0.8	-0.3	0.2	-1.2	-1.0	-0.2	-1.0
Pain type(s) experienced in last month: Hip pain	0.5	0.6	1.6	-0.8	-0.7	-1.3	-1.0	-0.2	-0.4	-0.5	-1.1	-0.7	0.6	-0.3
Illnesses of father: High blood pressure	0.5	0.6	1.3	-1.1	-0.8	-0.6	-0.9	-0.0	-1.1	-0.6	-1.1	-0.7	0.0	-0.7
Ever had prostate specific antigen (PSA) test	0.5	0.6	1.0	1.0	-0.0	0.9	0.9	0.6	0.5	0.9	0.9	0.7	0.9	0.7
Myopia	0.5	0.8	2.5	-0.3	-1.6	-0.0	-0.5	-1.0	-1.1	-0.5	-0.0	-0.2	-0.9	-1.5
Worry (Nagel 2018)	0.4	0.8	1.7	0.9	0.5	1.3	0.2	0.2	0.8	1.1	1.0	1.0	0.8	1.2
Hypothyroidism (self reported)	0.4	0.8	2.3	-0.8	0.5	-1.5	0.7	1.5	0.2	1.5	-0.6	-0.5	0.3	0.1
Lung FEV1/FVC ratio	0.4	2.2	7.6	-1.2	-0.8	-2.5	0.8	1.4	-0.5	0.1	-1.8	-2.8	-1.4	-0.2
Systolic blood pressure, automated reading	0.4	1.0	3.6	1.8	1.4	0.4	-1.9	-1.3	-0.4	-0.5	-0.2	0.3	-0.1	0.6
Taking other prescription medications	0.4	0.5	2.2	1.1	0.6	0.5	0.0	0.6	0.9	0.4	0.1	0.6	1.5	0.4
Serious illness, injury or assault to yourself	0.4	0.5	2.8	0.6	0.0	0.3	-0.4	-1.4	-0.3	-1.7	0.5	0.2	-0.0	-0.0
Past tobacco smoking	0.4	0.7	1.7	0.3	0.4	0.6	1.3	0.8	0.9	0.6	1.0	0.6	1.3	0.2
Allergy	0.4	0.9	3.1	1.1	0.7	1.8	-0.5	-0.3	-0.4	-1.0	1.3	1.2	-0.6	-0.6
Exposure to tobacco smoke at home	0.4	0.5	1.9	0.3	-0.4	-0.3	-0.9	-1.4	-0.9	-1.0	0.2	0.1	-0.5	-0.4
Hair/balding pattern: Pattern 4	0.4	1.0	2.7	-0.4	-0.8	-1.2	-0.4	-0.8	-1.5	0.2	-0.3	-1.3	-1.1	-1.6
Mouth/teeth dental problems: Bleeding gums	0.4	0.5	1.3	0.4	0.4	-0.8	0.8	1.1	1.1	0.8	0.1	-0.2	0.2	0.9
Body fat percentage	0.4	1.4	3.0	1.7	1.3	-0.1	0.9	0.3	1.3	1.6	1.3	0.9	0.8	1.6
Reason for reducing amount of alcohol drunk: Health precaution	0.4	0.4	1.4	0.5	1.2	0.0	0.1	0.8	0.9	0.8	0.3	0.2	0.6	0.5
Pulse wave peak to peak time	0.4	0.4	1.2	0.6	-0.3	0.6	-0.1	-0.3	0.4	0.7	1.0	0.9	1.1	0.1
Health satisfaction	0.4	0.6	2.6	1.6	-0.7	-1.1	0.6	-0.6	0.3	-0.1	0.8	-0.5	-0.1	0.7
Medication: Omeprazole	0.4	0.5	1.1	0.2	-0.7	-1.0	1.0	0.4	0.1	0.6	-0.1	-1.0	0.8	1.0
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.4	0.5	1.7	1.3	1.3	-1.0	-0.3	-0.4	0.2	-0.3	-0.7	-0.6	0.4	0.4
Overall health rating	0.4	0.8	1.7	1.3	1.1	-0.4	-0.5	-1.1	0.6	0.7	0.4	0.1	1.3	1.2
Qualifications: NVQ or HND or HNC or equivalent	0.4	0.5	1.2	-0.8	-0.9	-0.3	-0.2	0.1	-0.3	-1.1	-0.7	-0.6	-0.4	-1.1
Knee pain experienced in last month	0.4	0.6	2.4	-0.7	0.2	-1.6	0.2	0.7	0.1	0.2	-1.0	-1.2	-0.8	-0.1
Commuting to job workplace: Walk	0.4	0.4	1.8	0.9	1.3	-0.4	-0.2	-1.0	0.2	0.6	0.1	0.1	-0.5	-0.4
Mother’s age at death	0.4	0.5	2.1	-0.4	-0.7	-1.2	0.6	0.3	-0.2	0.1	-0.9	-1.5	-0.1	-0.1
Medication: Blood pressure	0.4	0.7	4.6	1.0	2.1	-0.5	-0.0	0.3	0.3	0.8	-0.1	-0.2	-0.4	0.7
Supplements: Fish oil (including cod liver oil)	0.4	0.5	2.3	-0.6	1.5	-0.2	-0.5	1.1	0.1	0.4	-0.9	-0.2	0.8	0.0
Medication: Paracetamol	0.4	0.7	1.9	0.8	0.2	0.6	0.3	0.1	1.1	1.4	0.7	1.0	1.2	0.5
Vascular/heart problems diagnosed by doctor	0.4	1.0	6.8	-2.6	-0.8	0.3	-0.2	0.9	0.2	-0.2	-1.0	0.1	0.4	-1.2
Cholesterol lowering medication	0.4	0.6	2.9	1.2	1.7	0.4	0.1	-0.1	0.5	0.6	0.8	0.6	0.4	0.4
Schizophrenia vs Biploar Disorder	0.3	0.4	0.8	0.4	0.8	0.9	0.5	0.5	0.9	0.5	0.5	0.9	0.4	0.5
Alzheimer’s Disease (including proxy)	0.3	0.5	1.1	0.1	-1.0	-0.7	-0.0	-0.5	-1.0	-0.8	-0.2	-0.7	-1.1	-0.2
Ovarian Cancer	0.3	0.3	0.9	0.6	-0.9	-1.0	0.7	-0.3	-0.3	-0.2	0.2	-0.9	-0.2	0.4
HbA1C	0.3	0.3	1.2	0.5	0.2	0.4	-0.1	0.7	-0.1	1.1	0.4	0.6	0.3	-0.5
Neuroticism (2016)	0.3	0.4	3.9	-0.3	2.0	-0.2	-0.1	0.0	0.4	0.7	-0.0	0.3	-0.3	0.2
Blood Eosinophil Count	0.3	2.4	7.8	0.7	0.8	0.1	2.1	2.4	1.7	2.8	0.8	0.0	0.3	1.9
Height	0.3	6.3	14.8	-3.4	-2.3	-1.3	0.8	3.5	-1.1	-1.9	-3.5	-3.9	1.9	-1.7
Systolic Blood Pressure	0.3	1.7	5.2	2.3	1.1	-0.2	-1.9	-2.3	-1.2	-0.7	0.0	-0.5	-1.1	0.2
Respiratory disease	0.3	0.7	1.4	1.1	-0.1	0.4	1.1	-0.2	0.7	1.1	0.9	0.2	0.9	1.2
Type 2 Diabetes (T2D) (2018)	0.3	0.5	3.5	1.9	-0.1	0.0	0.3	-0.4	-0.0	-0.5	1.0	-0.1	0.2	0.8
Other serious medical condition/disability diagnosed by doctor	0.3	0.3	3.4	0.1	-0.3	-0.0	0.2	0.0	0.2	-0.0	0.3	0.1	1.8	0.4
Diabetes (mother)	0.3	0.3	0.8	-0.6	0.6	0.0	-0.9	-0.8	-0.5	-0.8	-0.6	0.1	0.5	-0.2
Pack years adult smoking proportion	0.3	0.5	1.9	-0.0	1.1	-0.2	-1.4	-0.6	-0.8	0.4	-0.4	-0.2	-0.2	0.9
Age when periods started (menarche)	0.3	0.8	2.3	-1.1	0.3	-0.9	-1.1	-0.8	-0.6	-0.7	-1.2	-0.7	-1.5	-0.5
Nervous feelings	0.3	0.5	1.6	-0.6	1.2	0.3	-1.3	-1.2	-0.6	-0.1	-0.1	0.3	0.0	-0.3
Hair/balding pattern: Pattern 2	0.3	0.4	1.7	-1.3	0.0	-0.7	0.5	1.0	0.5	0.1	-0.9	-0.5	0.0	-0.1
Diabetes (self-reported)	0.3	0.4	1.5	1.2	0.4	-0.1	0.6	-0.3	0.4	0.2	1.0	0.1	0.8	0.6
Hayfever/allergic rhinitis (self-reported)	0.3	0.3	1.6	0.3	0.6	-0.0	0.5	0.8	1.3	0.8	-0.2	-0.0	0.4	0.2
Father’s age at death	0.3	0.4	2.0	-0.6	-0.8	0.4	-0.8	-0.2	-0.8	-1.4	-0.3	0.3	0.1	-0.2
Happiness	0.3	0.3	1.0	1.0	0.2	0.5	0.7	0.2	0.9	-0.3	0.6	0.4	-0.5	0.6
Noisy workplace	0.3	0.4	1.1	-0.3	1.1	-0.2	0.4	0.4	0.6	1.0	0.3	0.3	0.7	0.6
Qualifications: A levels/AS levels or equivalent	0.3	0.6	3.3	1.8	-0.1	-0.0	0.8	-0.3	0.3	-0.8	0.6	-0.3	0.6	0.9
Medication: Lansoprazole	0.3	0.4	1.3	-0.5	0.7	0.4	0.1	1.2	0.4	-0.5	-0.4	-0.2	1.1	-0.3
Standing height	0.3	3.3	12.6	-1.5	-1.9	-0.8	2.3	3.5	0.3	-0.1	-1.4	-2.4	1.9	-0.5
Tense / ‘highly strung’	0.3	0.5	2.1	0.6	1.4	0.4	-0.2	0.2	0.4	1.1	0.4	0.5	0.9	0.3
Emphysema/chronic bronchitis	0.3	0.3	1.6	0.0	1.3	0.3	-0.2	-0.8	-0.3	-0.8	0.2	0.5	0.4	0.1
Neck or shoulder pain in last month	0.3	0.5	1.5	-0.3	0.4	0.3	0.1	1.0	1.0	0.4	0.2	0.8	1.2	-0.5
Heart disease (mother)	0.3	0.4	2.4	0.7	1.6	0.4	-0.3	0.4	0.1	0.3	0.1	0.7	-0.3	0.4
Suffer from ‘nerves’	0.3	0.5	1.4	0.0	0.7	0.8	-0.3	0.6	0.6	1.2	0.1	0.7	1.0	0.9
Long-standing illness, disability or infirmity	0.3	0.4	2.4	0.7	1.6	-0.3	-0.5	0.1	0.0	0.1	-0.1	-0.1	1.2	-0.1
Diabetes diagnosed by doctor	0.3	0.6	2.1	1.4	1.3	0.1	0.4	0.1	0.5	-0.2	0.8	0.2	0.7	0.8
Guilty feelings	0.3	0.4	1.4	-0.1	-1.2	0.1	1.1	0.6	0.3	0.5	0.7	-0.0	0.6	0.8
Hearing aid user	0.3	0.4	2.3	-0.5	1.5	0.3	-0.9	-0.0	-0.3	-0.3	-0.2	0.7	0.2	-0.1
Financial situation satisfaction	0.3	0.4	1.5	0.1	0.1	-0.9	0.5	0.3	0.6	-0.1	-0.3	-0.8	-0.4	1.2
Medication: Lisinopril	0.3	0.3	0.8	0.8	0.7	-0.6	-0.6	-0.9	-0.7	-0.3	0.1	-0.5	-0.6	-0.3
Age started oral contraceptive pill	0.3	0.4	1.5	-0.7	0.7	0.4	-0.5	0.5	-0.3	-1.2	-1.1	-0.2	0.4	-0.2
Pain experienced in last month	0.3	0.4	1.6	-0.0	-0.4	-0.3	-0.0	-0.8	-1.3	-0.3	-0.1	-0.9	-1.2	0.0
Alcohol drinker status: Previous	0.3	0.3	2.1	0.3	1.4	-0.2	-0.0	0.2	0.1	0.9	0.1	-0.0	0.4	0.3
Pack years of smoking	0.3	0.4	1.5	-0.1	1.1	-0.1	-1.2	-0.5	-0.7	0.2	-0.3	-0.0	-0.0	0.9
Intelligence (Savage-Jansen 2018)	0.2	0.5	3.5	-1.0	-1.9	-0.7	-0.1	-0.1	-0.3	-0.3	-0.5	-0.5	-0.3	0.0
Alzheimer’s Disease (in father)	0.2	0.3	0.6	0.8	0.4	0.6	0.6	0.0	0.6	0.3	0.4	0.5	0.3	0.7
Crohns Disease (2017)	0.2	0.5	1.8	0.7	-0.0	-0.6	1.4	0.9	0.7	0.6	0.5	-0.2	0.5	0.6
Crohns Disease (2012)	0.2	0.3	1.6	0.6	0.3	-0.6	0.5	0.1	0.5	0.9	0.4	-0.0	-0.1	1.3
Medication: Metformin	0.2	0.3	0.8	0.3	0.4	-0.6	-0.5	-0.7	-0.4	-0.9	-0.4	-0.7	-0.3	0.2
Number of incorrect matches in round	0.2	0.4	1.2	-1.1	0.5	0.5	-1.0	-0.5	-0.1	0.6	-0.5	0.3	-0.4	-0.6
Alcohol usually taken with meals	0.2	0.3	0.8	-0.9	-0.2	-0.5	0.1	0.5	-0.5	0.9	-0.2	-0.4	-0.1	-0.6
Fluid intelligence score	0.2	0.5	2.1	0.9	-0.4	-0.1	0.3	0.4	0.7	0.6	0.3	0.2	0.9	1.4
Alcohol intake versus 10 years previously	0.2	0.3	1.6	-0.7	1.2	-0.3	-0.0	0.5	0.4	-0.0	-0.3	0.1	-0.3	-0.5
Falls in the last year	0.2	0.3	1.9	-0.0	-0.4	-1.4	0.4	-0.0	-0.0	-0.4	-0.2	-0.9	-0.3	-0.0
Number of live births	0.2	0.2	0.6	-0.7	-0.6	0.2	0.0	-0.8	-0.7	-0.2	-0.2	-0.2	-0.6	-0.6
Pulse rate	0.2	0.3	1.6	0.1	0.3	0.3	-0.4	-1.1	-0.3	-0.2	0.3	0.3	0.5	-1.3
Medication: Paracetamol	0.2	0.3	0.9	0.5	0.3	0.2	0.3	0.4	0.7	1.0	0.4	0.7	0.8	0.1
Medication: Seretide 50 evohaler	0.2	0.2	0.6	-0.3	0.6	-0.2	-0.8	-0.3	-0.5	-0.4	-0.4	-0.1	-0.4	-0.5
Age at last live birth	0.2	0.3	1.9	-0.1	0.7	0.2	0.0	0.1	0.4	1.4	0.2	0.6	0.2	0.6
Smoking status: Previous	0.2	0.3	0.6	0.7	-0.5	0.1	-0.6	-0.6	-0.2	-0.4	-0.4	-0.2	-0.6	0.7
Friendships satisfaction	0.2	0.3	0.6	-0.1	0.3	-0.8	0.1	0.5	0.1	-0.7	-0.7	-0.8	-0.5	-0.4
Number of self-reported non-cancer illnesses	0.2	0.4	1.3	1.1	-0.2	-1.0	-0.3	-0.7	-0.5	-0.3	-0.2	-0.9	-0.2	0.1
Tinnitus: Yes, now most or all of the time	0.2	0.2	0.6	-0.1	-0.5	0.0	-0.8	-0.6	-0.5	-0.4	-0.3	-0.2	-0.6	-0.5
Average weekly beer plus cider intake	0.2	0.3	0.7	-0.4	-0.7	-0.2	-0.5	-0.7	-0.3	-0.5	-0.2	-0.1	-0.9	-0.6
Heart disease (siblings)	0.2	0.2	1.0	-0.1	-0.1	-0.6	0.2	0.8	0.1	1.0	-0.3	-0.6	0.4	-0.1
Ulcerative Colitis (UC)	0.1	0.3	1.0	-1.0	-0.2	-0.3	-0.6	-0.6	-0.4	-0.6	-0.5	-0.4	-0.4	0.2
Body Mass Index (BMI) (2010)	0.1	0.1	0.7	-0.2	-0.4	-0.3	-0.6	-0.4	-0.8	0.0	-0.2	0.0	0.0	0.0
LDL Cholesterol	0.1	0.1	0.4	-0.1	-0.7	0.0	0.3	0.2	-0.3	0.4	-0.1	0.0	0.0	0.0
Lupus	0.1	0.1	0.5	0.3	0.3	0.4	-0.5	-0.7	-0.1	-0.3	-0.3	-0.2	0.2	0.3
Smoking Status	0.1	0.2	0.8	-0.5	0.9	-0.1	-0.5	0.5	-0.3	0.3	-0.6	-0.1	0.2	-0.4
Hair Pigment	0.1	3.2	14.1	0.4	-0.1	-0.8	3.8	3.0	2.2	1.9	0.9	-0.8	0.8	0.8
Tanning	0.1	1.1	3.1	-1.7	-1.3	-1.0	1.1	1.1	-0.0	-0.4	-0.4	-0.8	-1.8	-0.5
Trunk fat percentage	0.1	0.5	1.2	1.0	0.7	-0.7	0.5	0.0	0.6	0.9	0.6	0.1	0.3	1.1
Frequency of tenseness / restlessness in last 2 weeks	0.1	0.2	1.0	-0.5	0.3	-0.1	0.3	1.0	0.4	0.7	0.0	0.0	0.6	0.2
Pain all over the body in last month	0.1	0.1	0.6	0.4	0.7	-0.1	0.4	0.3	0.6	-0.2	0.1	0.0	0.5	0.2
Lung cancer (father)	0.1	0.2	0.5	0.5	-0.1	-0.3	0.3	0.1	0.2	0.3	0.2	-0.5	0.6	-0.7
Glaucoma (self-reported)	0.1	0.1	0.4	0.0	-0.2	0.5	0.4	0.7	0.4	0.2	0.1	0.0	0.5	-0.2
Number of children fathered	0.1	0.1	0.4	-0.1	0.1	-0.2	0.5	-0.1	0.1	0.4	0.6	0.2	-0.4	0.3
Pulse rate, automated reading	0.1	0.4	1.0	0.8	0.0	-0.2	0.4	-1.0	-0.3	-0.2	0.7	-0.1	-1.0	-1.0
Alcohol intake frequency.	0.1	0.3	0.6	-0.7	-0.4	-0.5	-0.6	0.1	-0.7	-0.6	-0.8	-0.7	0.4	-0.3
Forced expiratory volume in 1-second (FEV1), predicted	0.1	0.3	1.6	-0.6	-1.3	-0.1	0.4	0.3	-0.1	-0.1	-0.4	-0.8	0.2	0.4
Handedness (chirality/laterality): Left-handed	0.1	0.2	0.4	0.0	0.6	-0.5	0.2	-0.4	0.0	0.7	-0.1	-0.6	-0.4	0.1
Wears glasses or contact lenses	0.1	0.1	0.5	-0.2	-0.2	0.1	-0.3	0.4	-0.1	-0.7	-0.3	-0.1	0.0	-0.7
Ever taken oral contraceptive pill	0.1	0.2	0.4	-0.3	-0.6	0.0	-0.4	-0.3	-0.3	0.5	-0.1	0.2	-0.6	0.4
Commuting to job workplace: Public transport	0.1	0.2	0.9	-0.1	-1.0	0.5	0.0	-0.6	-0.1	-0.0	0.3	0.3	0.2	-0.2
Irritable Bowel Disease (IBD)	0.0	0.1	0.2	-0.4	-0.4	-0.5	0.2	0.1	0.1	0.0	-0.1	-0.4	0.0	0.5
Major Depression (MDD)	0.0	0.0	0.4	0.7	0.0	0.0	0.0	-0.2	0.0	0.0	0.0	0.0	0.0	0.0
Blood Platelet Count	0.0	0.5	3.1	0.9	-0.3	0.6	-0.4	0.4	0.1	-0.3	0.3	0.5	1.8	-0.3

Hub : Genes

ABCB8

Models

Trait associations