Best TWAS P=1.01e-08 · Best GWAS P=3.44e-09 conditioned to 0.0125
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Esophagus Muscularis | PTPDC1 | 0.15 | 0 | lasso | 4 | 0.03 | 0.00609 | 4.1 | -5.6 | 1.8e-08 | 0.32 | 0.22 | 0.41 | FALSE |
2 | NTR | Blood | ZNF169 | 0.02 | 0 | lasso | 6 | 0.00 | 0.01100 | 5.3 | 5.7 | 1.0e-08 | -0.47 | 0.07 | 0.25 | TRUE |
3 | The Cancer Genome Atlas | Breast Invasive Carcinoma | BARX1 | 0.04 | 0 | blup | 66 | 0.01 | 0.00063 | 3.8 | -5.6 | 2.2e-08 | 0.39 | 0.01 | 0.78 | TRUE |