Hub : Genes

ZNF169

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.0960 0.0300 8.3e-06 0.073 0.042 0.063 0.057 0.062 3.2e-09 6.2e-06 3.5e-08 1.6e-07 4.7e-08
2 GTEx Colon Transverse 0.2400 0.0870 2.4e-03 0.135 NA 0.021 NA 0.122 5.7e-07 NA 3.5e-02 NA 2.0e-06
3 GTEx Esophagus Muscularis 0.1390 0.0550 8.8e-04 -0.005 NA 0.001 NA -0.003 9.8e-01 NA 2.5e-01 NA 5.7e-01
4 GTEx Thyroid 0.0930 0.0410 2.7e-03 0.029 NA 0.042 NA 0.046 2.5e-03 NA 3.6e-04 NA 1.9e-04
5 NTR Blood 0.0150 0.0072 8.1e-03 0.001 0.004 0.000 0.004 0.004 1.0e-01 1.8e-02 2.5e-01 1.9e-02 1.1e-02
6 ROSMAP Brain Pre-frontal Cortex 0.1161 0.0331 8.4e-08 0.040 0.069 0.045 0.067 0.046 6.9e-06 2.9e-09 1.7e-06 4.8e-09 1.3e-06
7 YFS Blood 0.0553 0.0196 1.9e-06 0.022 0.019 0.030 0.032 0.022 6.1e-08 4.4e-07 4.6e-10 8.0e-11 6.4e-08
8 TCGA Brain Lower Grade Glioma 0.0643 0.0305 1.8e-04 0.002 0.033 0.038 NA 0.011 1.8e-01 1.1e-04 3.1e-05 NA 1.8e-02

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
Bipolar Disorder (2018) 0.2 0.4 2.1 -0.2 0.4 0.0 -0.5 0.4 1.5 0.5 0.0
Bipolar Disorder or Schizophrenia 0.3 0.7 2.4 -0.5 1.2 0.0 -0.5 0.1 1.6 0.8 -0.6
Depressed Affect (Nagel 2018) 1.1 2.4 5.9 -0.5 1.1 0.0 -2.3 1.9 1.7 0.0 2.4
Depression (Nagel 2018) 0.6 0.9 3.3 -0.7 -0.2 0.0 -0.5 1.8 1.5 -0.2 0.8
Intelligence (Savage-Jansen 2018) 0.3 1.0 5.2 0.7 1.4 0.0 -0.0 -2.3 -0.4 0.6 -0.1
Neuroticism (Nagel 2018) 1.4 3.2 7.7 -0.9 1.1 0.0 -2.6 2.8 1.6 0.2 2.6
Schizophrenia (2018) 0.2 0.5 1.5 -0.5 1.2 0.0 -0.2 -0.1 0.8 0.6 -0.8
Schizophrenia vs Biploar Disorder 0.3 0.4 1.8 -0.5 0.0 0.0 0.0 -0.7 -0.1 1.0 -1.3
Worry (Nagel 2018) 1.4 3.0 7.0 -1.0 2.1 0.0 -2.7 2.1 0.9 0.0 2.5
Alzheimer’s Disease (in mother) 0.6 0.7 3.1 1.7 -0.3 0.0 -0.0 1.3 0.5 -0.6 0.5
Alzheimer’s Disease (in father) 0.1 0.1 0.3 0.2 -0.3 0.0 -0.1 0.5 0.5 -0.2 0.4
Alzheimer’s Disease (including proxy) 0.4 0.6 2.1 1.5 -0.3 0.0 0.2 1.3 0.5 -0.1 0.9
Crohns Disease (2017) 0.3 0.6 3.0 -0.7 -0.6 0.0 0.8 0.2 0.2 0.1 -1.7
Irritable Bowel Disease (IBD) 0.5 1.1 2.7 -1.3 -1.4 0.0 1.0 1.6 1.0 0.6 -0.6
Ulcerative Colitis (UC) 0.7 1.3 4.1 -1.4 -0.8 0.0 0.0 2.0 1.7 0.5 0.5
Major Depression (MDD) 3.3 4.0 14.0 -3.2 -1.1 0.0 -0.6 1.0 1.6 3.7 1.7
Reaction Time 0.3 0.6 2.4 1.0 -1.0 0.0 -0.4 0.1 -1.5 -0.6 0.2
Verbal and Numeric Reasoning (VNR) 0.5 1.3 3.4 0.7 1.1 0.0 -0.6 -1.8 1.2 1.4 1.0
Breast Cancer 1.1 2.6 8.2 1.6 0.9 0.0 1.5 0.4 -0.3 -2.9 -2.6
Ovarian Cancer 1.0 1.3 3.8 0.8 0.9 0.0 -1.2 1.7 1.9 -0.7 0.8
Prostate Cancer 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
Age at First Birth 0.4 0.6 2.1 0.1 0.7 0.0 -0.7 1.5 0.8 0.7 0.2
Bipolar Disorder (2011) 0.1 0.1 0.4 -0.2 0.4 0.0 -0.6 -0.1 0.3 0.6 -0.2
Body Mass Index (BMI) (2010) 0.4 0.6 1.8 0.7 0.7 0.0 -1.4 0.2 0.7 -0.9 0.5
Coronary Artery Disease (CAD) 0.9 1.1 3.3 0.1 -1.8 0.0 0.6 0.8 0.6 1.7 1.1
Crohns Disease (2012) 0.2 0.4 1.6 0.2 0.1 0.0 1.1 0.0 0.1 0.3 -1.3
Mean Putamen Volume 1.5 1.7 4.6 -1.7 -0.5 0.0 1.3 -0.6 -1.8 -1.0 -2.2
Fasting Glucose 0.5 0.6 1.9 -0.6 1.4 0.0 0.4 0.8 1.1 0.7 -0.1
HbA1C 1.0 1.1 3.1 -0.9 1.3 0.0 -1.0 1.8 1.3 -0.5 0.8
HDL Cholesterol 1.1 1.9 5.6 -0.6 -1.3 0.0 1.9 -1.4 -1.1 -1.0 -2.4
LDL Cholesterol 0.1 0.2 1.3 -1.1 0.3 0.0 -0.1 -0.4 -0.3 0.1 -0.5
Lupus 0.9 1.4 3.0 1.6 -1.7 0.0 1.1 -0.6 -1.0 -1.7 -0.2
Neuroticism (2016) 1.1 1.6 3.4 -1.5 -1.5 0.0 -1.0 1.8 1.4 -0.7 1.1
Primary Biliary Cirrhosis 0.3 0.4 1.7 1.1 -0.2 0.0 -0.2 -0.5 1.3 -0.6 0.0
Rheumatoid Arthritis 0.3 0.4 1.4 -0.0 -1.0 0.0 0.1 -1.2 -0.0 0.7 0.4
Schizophrenia (2014) 0.4 1.0 3.3 0.2 1.2 0.0 0.3 -1.8 0.7 1.1 -1.1
Triglycerides 0.9 1.4 4.4 -0.4 1.1 0.0 -2.1 0.4 1.1 0.9 1.8
Type 2 Diabetes (T2D) (2012) 1.4 1.7 5.0 -0.6 1.2 0.0 -1.9 1.3 2.2 0.9 0.7
Ulcerative Colitis 0.6 0.8 3.8 -0.0 -1.0 0.0 1.9 1.2 -0.1 -0.4 0.1
Blood Eosinophil Count 0.5 4.1 24.0 -1.8 -1.1 0.0 -1.3 4.9 -0.1 0.1 1.6
Blood Platelet Count 0.3 3.7 11.2 -2.2 1.3 0.0 -2.8 3.4 1.9 0.5 0.8
Blood Red Count 0.2 1.8 4.4 -2.1 -1.3 0.0 -0.5 1.3 -1.7 1.2 1.4
Blood White Count 0.6 4.1 21.3 -1.8 -0.9 0.0 -1.0 4.6 -1.3 1.9 1.3
Heel T-Score 4.5 35.5 151.3 -4.6 -1.9 0.0 -6.4 12.3 2.0 3.2 7.2
BMI 0.9 5.3 16.6 0.0 1.9 0.0 -4.1 3.2 -0.3 -1.2 3.2
Height 1.5 29.3 116.6 2.7 6.2 0.0 5.3 -10.8 2.7 -2.8 -5.3
Waist Hip Ratio (WHR) 0.6 2.6 6.6 -2.6 0.9 0.0 -1.5 1.1 2.4 0.6 -1.9
Systolic Blood Pressure 0.2 1.2 3.0 -1.4 -1.7 0.0 1.2 0.1 0.0 1.3 -1.0
Smoking Status 0.6 1.3 3.4 1.8 -1.6 0.0 1.8 -0.3 0.3 -0.7 -0.7
Allergy or Eczema 0.6 1.6 5.8 -2.4 0.8 0.0 -0.9 1.4 1.7 -0.9 -0.3
Cardiovascular Disease 0.2 0.5 1.9 -1.4 0.1 0.0 0.2 0.8 0.0 0.3 -1.2
Hypothyroidism (self reported) 0.2 0.4 1.9 1.4 -0.4 0.0 -0.3 0.7 -0.3 -0.3 0.3
Respiratory disease 1.6 3.5 19.6 -1.0 -1.6 0.0 -0.6 4.4 0.4 0.5 2.1
Type 2 Diabetes (T2D) (2018) 1.2 2.2 5.6 -1.5 0.9 0.0 -1.7 2.4 1.9 1.4 0.6
Lung FEV1/FVC ratio 0.4 2.2 6.1 -0.3 1.2 0.0 -0.9 -0.4 -1.7 -2.5 -2.5
Lung FVC 0.2 1.1 3.6 0.7 -1.0 0.0 0.9 -0.7 -0.9 -1.4 -1.9
Neuroticism 1.7 4.1 10.8 -2.0 1.1 0.0 -3.0 3.3 1.3 0.3 2.5
Chronotype (morning person) 0.3 0.8 2.3 -0.7 1.5 0.0 -1.2 -0.3 0.3 1.2 0.4
Hair Pigment 0.0 1.1 4.2 0.9 0.4 0.0 -0.5 -0.4 1.3 -2.0 -1.2
Tanning 0.1 1.8 7.2 0.6 -0.0 0.0 1.8 -1.8 -2.7 0.2 -0.5
Hand grip strength (left) 0.6 1.5 5.2 0.2 2.3 0.0 -0.8 -1.4 1.9 -0.6 0.0
Number of treatments/medications taken 0.5 0.9 4.5 -0.3 -1.6 0.0 0.6 2.1 0.1 -0.2 -0.1
Average weekly spirits intake 0.1 0.1 0.5 -0.1 -0.0 0.0 -0.2 -0.3 -0.0 0.5 0.7
Sensitivity / hurt feelings 2.0 3.5 8.5 -2.9 -0.4 0.0 -2.3 2.7 1.4 1.3 1.7
Frequency of depressed mood in last 2 weeks 0.9 1.3 3.9 -1.4 0.3 0.0 -1.5 2.0 1.0 -0.8 0.9
Hearing difficulty/problems: Yes 0.8 1.2 3.4 0.6 0.4 0.0 -0.9 1.8 1.5 1.5 0.8
Relative age of first facial hair 1.8 3.7 8.7 2.1 1.3 0.0 1.4 -2.5 -1.9 -1.8 -3.0
Other serious medical condition/disability diagnosed by doctor 0.4 0.5 1.8 -0.5 1.3 0.0 -1.3 -0.4 0.0 0.1 0.3
Ever used hormone-replacement therapy (HRT) 0.6 0.8 3.5 0.3 -0.5 0.0 -0.8 1.9 0.2 -0.9 1.0
Ever had hysterectomy (womb removed) 0.4 0.5 1.5 0.5 -1.2 0.0 0.3 1.0 0.6 -0.3 0.8
Systolic blood pressure, automated reading 0.2 0.5 1.1 -0.8 -0.9 0.0 0.7 0.8 -0.2 -0.2 -1.1
Eye problems/disorders: Diabetes related eye disease 0.8 0.8 3.1 -0.1 -0.1 0.0 -0.5 0.2 1.8 1.4 1.1
Angina 0.6 0.8 2.7 -0.0 -0.8 0.0 1.2 -0.5 -0.4 -1.6 -1.2
Medication for hormone replacement therapy 0.6 0.6 1.3 0.3 -0.6 0.0 0.6 -1.1 -1.0 -0.8 -1.1
Vitamin and mineral supplements 0.7 1.0 4.5 -0.7 -0.9 0.0 0.7 -0.3 -0.5 2.1 1.1
Supplements: Zinc 0.9 0.9 2.7 0.6 0.9 0.0 -0.3 -0.8 -0.3 -1.6 -1.6
Medication: Co-codamol 0.5 0.6 1.7 -1.2 -1.3 0.0 0.5 0.7 1.0 0.0 -0.0
Medication: Metformin 1.0 1.5 4.5 -1.1 0.5 0.0 -1.3 1.5 2.1 0.9 1.1
Diabetes (father) 1.7 2.1 4.7 -2.2 1.0 0.0 -1.5 2.0 1.3 1.6 0.9
Diabetes (mother) 2.1 2.6 8.1 -0.8 0.5 0.0 -1.2 2.8 1.8 1.7 2.2
Severe depression (siblings) 0.4 0.5 1.3 -0.5 -0.7 0.0 1.1 -1.1 -0.0 0.4 -0.6
Pack years adult smoking proportion 0.9 1.3 5.3 -0.4 -2.3 0.0 -0.5 0.7 1.7 0.6 1.1
Impedance of leg (right) 0.5 2.5 5.9 -2.4 -1.1 0.0 1.9 -1.4 0.9 1.2 -2.3
Leg fat-free mass (left) 0.6 3.1 15.1 0.9 3.9 0.0 -0.8 -1.6 0.8 -2.3 0.6
Trunk fat percentage 0.5 2.1 5.1 -1.5 0.9 0.0 -2.2 2.3 1.1 -1.5 0.8
Hand grip strength (right) 0.5 1.4 6.3 -0.4 1.7 0.0 -0.8 -0.7 2.5 -1.0 -0.2
Townsend deprivation index at recruitment 0.2 0.3 1.7 0.2 0.4 0.0 -0.3 0.5 -0.5 -1.3 -0.4
Current tobacco smoking 0.6 1.0 2.3 1.0 -1.5 0.0 1.1 -1.0 -0.8 -1.0 -1.2
Average weekly fortified wine intake 0.8 0.9 2.7 0.5 -0.8 0.0 1.7 -0.6 -0.4 -0.7 -1.6
Maternal smoking around birth 0.6 0.8 2.4 0.0 -1.5 0.0 1.4 -0.7 -1.2 0.2 -0.6
Fed-up feelings 1.1 2.1 7.4 -1.7 -0.2 0.0 -1.2 2.7 1.4 -0.0 1.7
Frequency of unenthusiasm / disinterest in last 2 weeks 0.8 1.1 4.8 -0.9 -0.9 0.0 -0.4 2.2 1.0 -1.0 0.7
Relative age voice broke 1.3 1.9 6.1 1.6 1.1 0.0 0.6 -2.5 -1.2 -0.9 -1.7
Taking other prescription medications 0.7 1.1 3.7 -1.7 -0.5 0.0 -0.6 1.9 0.9 0.6 0.4
Age when periods started (menarche) 0.3 0.8 3.6 -1.3 -0.0 0.0 -0.2 0.3 1.9 0.0 -0.9
Bilateral oophorectomy (both ovaries removed) 1.0 1.1 3.6 0.2 -1.4 0.0 0.0 1.9 -0.1 0.2 1.8
Heel bone mineral density (BMD) T-score, automated (left) 3.3 7.5 25.7 -1.1 -0.6 0.0 -2.9 5.1 1.7 2.3 4.0
Tinnitus: Yes, but not now, but have in the past 1.4 1.5 4.2 -0.8 1.0 0.0 -1.4 -2.0 -0.5 1.8 -0.9
Qualifications: CSEs or equivalent 0.6 0.8 1.9 0.4 -1.2 0.0 -0.0 0.9 1.4 1.0 1.2
Serious illness, injury or assault to yourself 0.4 0.5 2.1 -0.0 -0.4 0.0 0.6 -0.6 -0.7 -1.4 -0.8
High blood pressure 0.3 0.8 4.1 -0.6 0.2 0.0 -0.1 0.2 -0.1 -1.3 -2.0
Hayfever, allergic rhinitis or eczema 0.5 1.0 5.3 -2.3 -0.5 0.0 0.3 0.8 0.6 -1.0 -0.6
Multivitamins +/- minerals 0.7 0.9 4.1 1.4 0.7 0.0 -0.7 0.1 -0.1 -2.0 -0.4
Stomach or abdominal pain in last month 0.4 0.5 2.4 0.5 -0.2 0.0 -0.2 1.5 0.7 -0.6 0.6
Supplements: Glucosamine 0.7 0.9 3.7 0.8 1.9 0.0 0.0 0.3 -0.1 -0.7 -1.5
Diverticular disease/diverticulitis (self-reported) 0.5 0.6 1.6 -0.3 -1.2 0.0 -0.1 1.2 0.4 0.6 1.3
Medication: Atenolol 0.3 0.3 0.8 -0.5 -0.8 0.0 0.5 -0.5 -0.9 -0.5 0.1
Medication: Levothyroxine sodium 0.1 0.2 0.6 0.4 0.6 0.0 -0.5 0.8 0.4 -0.3 -0.2
Sitting height 0.8 5.9 21.9 0.2 3.1 0.0 3.1 -4.7 1.2 -0.9 -1.9
Chronic bronchitis/emphysema (father) 1.7 2.0 4.0 -1.4 -2.0 0.0 -0.7 0.9 1.2 1.8 2.0
High blood pressure (mother) 0.2 0.2 1.0 -0.5 1.0 0.0 0.5 -0.2 0.4 0.3 -0.3
Body mass index (BMI) 1.2 4.9 15.4 -0.5 1.5 0.0 -3.9 3.3 0.6 -1.8 2.6
Impedance of leg (left) 0.5 2.4 6.2 -2.0 -1.3 0.0 1.8 -1.1 0.9 1.2 -2.5
Leg predicted mass (left) 0.6 3.2 15.3 0.9 3.9 0.0 -0.9 -1.6 0.8 -2.2 0.6
Trunk fat mass 0.5 2.3 5.3 -0.7 2.3 0.0 -2.1 1.0 1.3 -2.2 0.5
Waist circumference 1.1 4.1 9.7 -0.9 2.7 0.0 -3.1 2.4 1.7 -2.3 1.1
Number of incorrect matches in round 0.3 0.5 2.3 1.5 -0.4 0.0 0.4 -0.4 -0.6 -0.4 0.9
Past tobacco smoking 0.1 0.1 0.4 0.4 -0.1 0.0 -0.3 0.4 -0.6 0.1 0.1
Alcohol usually taken with meals 0.1 0.2 0.7 -0.4 0.5 0.0 0.1 -0.1 0.8 0.4 -0.4
Nervous feelings 1.9 3.6 13.4 -1.4 0.8 0.0 -2.2 3.7 0.7 0.6 2.6
Frequency of tenseness / restlessness in last 2 weeks 1.1 1.7 5.3 -1.1 1.1 0.0 -2.3 1.7 0.6 -1.5 0.7
Hearing difficulty/problems with background noise 1.5 2.3 4.9 -1.1 0.7 0.0 -2.2 1.8 1.4 1.8 2.0
Hair/balding pattern: Pattern 2 0.7 0.8 2.8 -1.1 0.7 0.0 -1.1 0.5 0.8 0.5 -1.7
Had menopause 0.5 0.7 2.4 0.6 -0.7 0.0 0.8 0.7 -1.6 -0.7 -0.7
Had other major operations 0.5 0.7 3.0 0.2 1.1 0.0 0.3 -1.7 -0.2 -0.9 -0.5
Forced vital capacity (FVC) 1.8 6.9 27.2 0.3 1.6 0.0 2.8 -5.2 0.1 -1.7 -3.8
Heel bone mineral density (BMD) T-score, automated (right) 4.5 10.3 32.8 -1.9 -0.0 0.0 -3.6 5.7 2.4 2.8 4.4
Ever unenthusiastic/disinterested for a whole week 1.9 2.3 9.9 -3.1 -0.5 0.0 -1.7 -0.3 1.0 2.0 0.5
Qualifications: None of the above 0.8 1.7 7.5 -0.3 0.1 0.0 -1.5 2.7 0.8 0.2 1.8
Financial difficulties in last 2 years 1.0 1.4 3.6 -1.7 0.2 0.0 -1.2 1.9 1.5 -0.1 0.9
Mouth/teeth dental problems 2.1 3.2 10.3 -2.9 1.3 0.0 -1.3 1.5 0.3 3.2 0.9
Heart attack 0.5 0.7 1.7 -1.3 -0.9 0.0 0.8 -0.8 -0.7 -0.2 -1.0
Allergy 0.8 1.9 7.2 2.7 0.3 0.0 0.5 -2.5 -1.1 0.3 -0.8
Pain all over the body in last month 0.5 0.5 2.0 -0.7 -0.7 0.0 -0.1 1.4 1.1 0.2 0.2
Diabetes (self-reported) 1.0 1.5 3.7 -0.5 1.0 0.0 -1.6 1.8 1.9 0.7 1.0
Hayfever/allergic rhinitis (self-reported) 0.7 1.0 3.3 -1.8 -0.8 0.0 -0.4 0.8 0.8 1.4 0.5
Medication: Ramipril 0.7 0.9 1.8 -0.8 -1.0 0.0 -0.3 1.4 1.1 0.9 1.3
Medication: Simvastatin 0.6 0.9 3.2 -1.8 -0.3 0.0 -0.3 0.8 1.3 1.2 0.4
Fluid intelligence score 0.3 0.6 3.6 0.9 0.6 0.0 -0.4 -1.9 0.2 0.2 -0.0
Illnesses of siblings 0.5 0.6 2.1 -1.3 0.1 0.0 -1.5 -0.2 1.0 -0.0 0.2
Neuroticism score 1.5 3.2 7.1 -2.5 1.0 0.0 -2.4 2.7 1.2 0.0 2.0
Weight 0.7 3.6 14.6 -0.2 3.8 0.0 -2.3 -0.2 1.6 -2.3 0.9
Impedance of arm (right) 0.4 2.0 5.8 -1.1 -1.8 0.0 2.4 -1.3 0.3 1.0 -1.8
Arm fat percentage (right) 0.8 3.3 10.4 -0.9 1.0 0.0 -3.2 2.7 0.6 -1.7 2.0
Trunk fat-free mass 1.2 6.8 25.8 1.9 5.1 0.0 0.3 -4.2 1.0 -2.5 -0.9
Hip circumference 0.7 3.1 7.4 0.2 2.6 0.0 -2.2 1.3 0.6 -2.7 2.0
Time employed in main current job 0.8 0.9 3.1 -0.7 -0.7 0.0 -0.0 1.8 0.1 1.4 1.1
Alcohol intake versus 10 years previously 0.5 0.7 2.2 -0.3 0.5 0.0 -1.3 1.0 0.3 -0.4 1.5
Father’s age at death 0.1 0.1 0.4 -0.3 -0.2 0.0 0.0 0.6 0.1 0.6 0.4
Worrier / anxious feelings 1.3 2.4 7.3 -1.1 1.5 0.0 -2.7 1.6 0.5 -0.3 2.3
Frequency of tiredness / lethargy in last 2 weeks 0.3 0.5 2.7 -0.9 -0.1 0.0 -0.7 1.6 -0.1 -0.5 0.1
Falls in the last year 0.8 1.0 3.0 1.4 0.3 0.0 -0.4 0.9 1.5 -1.7 0.0
Hair/balding pattern: Pattern 3 1.5 2.2 7.8 2.1 -0.3 0.0 1.1 -1.1 -1.4 -2.8 -0.9
Number of live births 0.4 0.5 1.4 0.7 0.4 0.0 -0.9 0.6 1.2 0.3 0.9
Forced expiratory volume in 1-second (FEV1) 2.0 6.6 23.9 0.7 1.8 0.0 2.1 -4.9 -0.6 -2.4 -3.9
Pulse rate 0.3 0.5 1.1 0.8 -0.2 0.0 -0.9 0.5 0.8 0.5 1.0
Happiness 1.0 1.2 3.7 1.0 1.9 0.0 -1.3 -1.2 0.3 -0.7 1.2
Noisy workplace 0.5 0.6 2.1 -1.1 -0.9 0.0 -0.1 1.4 -0.1 -1.0 0.1
Qualifications: A levels/AS levels or equivalent 2.5 5.4 13.5 2.0 1.6 0.0 2.0 -3.7 -2.4 -1.5 -3.4
Serious illness, injury or assault of a close relative in last 2 years 0.3 0.4 1.7 -0.5 0.6 0.0 0.3 -0.1 0.3 0.7 -1.3
Mouth/teeth dental problems: Dentures 0.8 1.3 4.3 1.7 0.1 0.0 -0.3 -1.4 0.7 -2.1 -0.9
Asthma 0.8 1.6 5.9 -1.9 -1.3 0.0 -0.1 2.4 0.2 1.1 0.7
Medication: Ibuprofen (e.g. Nurofen) 0.2 0.2 1.1 -0.2 0.3 0.0 -0.2 0.1 -0.2 -1.0 0.6
Medication: Cholesterol lowering 0.2 0.3 0.9 -0.9 -0.4 0.0 -0.3 0.3 0.6 -0.5 0.7
Depression (self-reported) 0.4 0.5 1.5 -1.0 -0.1 0.0 -0.2 1.1 -0.3 -1.2 -0.1
Medication: Lansoprazole 2.3 2.6 6.1 -0.1 0.8 0.0 -1.7 2.5 2.3 0.6 2.4
Prospective memory result 0.5 0.6 1.3 -0.7 0.1 0.0 -0.9 0.9 1.1 -0.8 1.1
Lung cancer (father) 0.5 0.5 1.4 -1.2 -0.7 0.0 -0.4 1.0 1.1 0.2 -0.1
Illnesses of mother 1.1 1.4 3.4 0.8 -0.6 0.0 1.2 -1.6 -1.1 -1.2 -1.9
Forced expiratory volume in 1-second (FEV1), Best measure 2.1 6.8 22.2 1.3 1.4 0.0 2.4 -4.7 -0.8 -2.5 -4.0
Pulse wave Arterial Stiffness index 1.9 2.2 6.6 0.7 1.3 0.0 -1.0 2.1 2.6 -0.4 1.8
Impedance of arm (left) 0.5 2.1 5.3 -1.5 -1.9 0.0 2.3 -0.6 0.6 1.6 -1.5
Arm fat mass (right) 0.8 3.1 8.9 -0.4 2.2 0.0 -3.0 1.7 1.0 -2.0 1.7
Trunk predicted mass 1.2 7.1 25.8 2.0 5.1 0.0 0.4 -4.2 0.9 -2.7 -0.9
Standing height 1.6 15.7 60.1 1.2 5.3 0.0 3.6 -7.8 2.2 -1.8 -3.8
Length of working week for main job 0.9 1.0 2.9 1.7 1.2 0.0 0.7 0.6 -0.8 -1.5 -0.3
Exposure to tobacco smoke at home 0.3 0.4 1.5 -0.1 0.3 0.0 -0.7 1.2 0.2 0.3 0.9
Breastfed as a baby 0.8 1.0 2.5 0.3 1.6 0.0 -1.3 -0.5 0.9 -1.3 -0.8
Tense / ‘highly strung’ 0.8 1.3 2.4 -1.1 1.5 0.0 -1.5 1.3 0.2 0.5 1.6
Seen doctor (GP) for nerves, anxiety, tension or depression 0.2 0.4 1.8 0.6 0.5 0.0 0.4 -0.3 -0.3 -1.4 0.1
Hair/balding pattern: Pattern 4 0.4 1.0 2.2 -1.3 -0.3 0.0 -1.3 1.5 -0.5 -0.4 1.5
Birth weight of first child 2.3 4.2 17.1 1.2 -0.2 0.0 2.9 -4.1 -0.6 -1.6 -1.9
Peak expiratory flow (PEF) 1.0 2.3 7.7 -0.5 1.1 0.0 0.8 -2.8 -0.1 -0.8 -2.8
Pulse wave reflection index 0.6 0.7 1.7 0.5 1.0 0.0 -0.5 1.3 1.3 -0.4 1.0
Ever highly irritable/argumentative for 2 days 0.7 0.8 2.0 -1.4 -1.0 0.0 0.5 -1.2 0.4 1.2 -0.3
Loud music exposure frequency 0.4 0.4 2.1 -0.6 -1.5 0.0 0.4 0.4 -0.5 0.6 0.0
Qualifications: O levels/GCSEs or equivalent 0.8 1.3 3.1 0.9 0.3 0.0 1.5 -1.6 -1.2 -0.5 -1.8
Mouth/teeth dental problems: Bleeding gums 1.7 2.2 4.3 1.4 -0.5 0.0 1.4 -1.8 -2.1 -1.6 -1.9
Blood clot in the leg (DVT) 2.3 3.0 11.5 -0.9 -0.4 0.0 -1.2 1.6 2.5 1.2 3.4
Medication: Paracetamol 0.6 1.0 4.6 1.1 -0.2 0.0 -0.6 2.1 -0.5 -0.6 1.2
Headache pain in last month 0.6 1.1 2.2 0.8 -1.0 0.0 1.5 -1.2 -1.2 -1.1 -0.9
Medication for cholesterol, blood pressure or diabetes 0.4 0.6 3.1 -0.6 0.3 0.0 -0.0 -0.5 0.9 1.8 -0.3
Glaucoma (self-reported) 0.2 0.3 1.5 0.6 1.2 0.0 0.0 0.3 0.2 -0.4 -0.0
Gout (self-reported) 0.3 0.4 1.2 -0.0 0.6 0.0 -0.4 1.1 0.5 0.8 0.9
Hypothyroidism/myxoedema (self-reported) 0.1 0.1 0.4 0.6 0.3 0.0 -0.6 0.2 0.4 -0.1 -0.3
Medication: Amlodipine 0.2 0.2 0.8 -0.3 0.0 0.0 -0.1 -0.9 0.0 -0.8 -0.5
Medication: Ventolin 100micrograms inhaler 0.8 1.0 4.8 -0.0 -0.4 0.0 -0.5 1.6 0.3 0.5 2.2
Birth weight 1.7 3.7 13.6 2.2 -0.2 0.0 2.0 -3.7 -0.8 -1.8 -1.8
Chronic bronchitis/emphysema (mother) 0.4 0.5 2.4 0.3 0.2 0.0 -0.4 0.3 1.5 0.5 0.9
High blood pressure (siblings) 0.3 0.4 1.8 1.4 0.5 0.0 0.8 -0.6 -0.2 0.1 -0.1
Forced vital capacity (FVC), Best measure 2.0 7.5 28.8 1.1 1.1 0.0 3.2 -5.4 -0.1 -2.0 -3.8
Body fat percentage 0.8 3.1 8.5 -1.9 0.8 0.0 -2.9 2.7 1.0 -1.3 1.2
Leg fat percentage (right) 1.3 4.9 14.8 -2.4 0.9 0.0 -3.8 3.3 1.3 -1.6 1.7
Arm fat-free mass (right) 0.8 4.1 20.3 1.2 4.5 0.0 -0.7 -2.2 1.1 -2.2 0.1
Exposure to tobacco smoke outside home 0.3 0.4 1.4 0.3 0.8 0.0 -0.7 1.2 -0.2 -0.8 0.3
Comparative body size at age 10 0.6 1.7 7.8 0.5 0.3 0.0 -1.3 1.2 1.2 0.9 2.8
Number of full brothers 1.8 2.2 8.1 0.3 0.6 0.0 -0.8 2.8 1.4 0.6 2.5
Worry too long after embarrassment 1.2 2.0 5.5 -2.4 -0.1 0.0 -1.7 1.6 1.7 0.7 1.2
Seen a psychiatrist for nerves, anxiety, tension or depression 1.9 2.5 13.1 1.0 3.6 0.0 -1.9 -0.5 -0.3 -1.5 0.0
Wheeze or whistling in the chest in last year 1.3 2.4 9.2 -0.1 -1.7 0.0 -0.5 3.0 1.4 -0.6 2.1
Number of children fathered 0.2 0.2 1.0 -0.4 1.0 0.0 0.2 0.1 0.5 -0.2 -0.1
Reason for reducing amount of alcohol drunk: Health precaution 0.6 0.7 1.7 1.3 0.8 0.0 -0.7 -0.6 -0.2 -1.3 -0.6
Age at first live birth 0.3 0.5 1.1 -0.6 0.8 0.0 0.4 -1.0 -0.3 0.5 -1.0
Pulse wave peak to peak time 2.0 2.3 7.1 -0.3 -0.5 0.0 1.1 -2.7 -2.4 0.1 -2.0
Health satisfaction 1.0 1.3 4.8 -0.6 -0.3 0.0 -1.3 1.2 0.9 1.0 2.2
Shortness of breath walking on level ground 0.7 0.9 4.0 -0.8 -0.6 0.0 -0.4 2.0 0.6 0.6 0.9
Qualifications: College or University degree 1.4 4.3 14.9 -0.4 1.9 0.0 2.0 -3.9 -0.7 -0.1 -3.4
Eye problems/disorders: None of the above 0.7 0.8 3.2 0.0 -0.8 0.0 1.0 -1.8 -0.2 0.8 -0.8
Mouth/teeth dental problems: Loose teeth 1.5 1.8 7.3 2.7 -0.4 0.0 1.7 -0.9 -0.1 -1.8 -0.5
Emphysema/chronic bronchitis 0.6 0.6 1.7 -1.2 0.2 0.0 -1.0 0.9 0.3 -0.2 1.3
Medication for pain relief, constipation, heartburn 0.3 0.5 1.9 -1.0 0.3 0.0 -0.2 -0.8 0.6 1.4 -0.4
Neck or shoulder pain in last month 0.4 0.5 1.7 0.2 1.3 0.0 -0.5 -0.5 -0.4 -1.1 -0.7
Medication: Blood pressure 0.2 0.4 1.4 0.3 -0.5 0.0 0.6 0.2 -0.8 -1.2 -0.6
Angina (self-reported) 0.6 0.8 3.3 -0.0 -1.0 0.0 1.2 -0.4 -0.2 -1.8 -1.0
Migraine (self-reported) 0.6 0.8 2.4 -1.0 0.1 0.0 -1.6 -0.6 0.8 1.1 0.7
Medication: Ibuprofen 0.1 0.1 0.2 -0.3 0.5 0.0 -0.2 -0.3 -0.1 -0.3 0.4
Medication: Allopurinol 0.2 0.3 0.9 0.2 0.2 0.0 -0.3 0.9 -0.6 -0.1 0.8
Medication: Omeprazole 0.3 0.3 1.7 -0.8 0.0 0.0 -0.2 0.2 0.4 1.3 0.3
Medication: Seretide 50 evohaler 0.9 1.1 2.6 -1.6 0.4 0.0 -1.6 1.4 0.0 0.6 0.9
Mean time to correctly identify matches 0.4 0.7 2.9 0.6 -1.7 0.0 -0.6 0.2 -1.2 -0.5 0.2
Heart disease (mother) 0.3 0.4 1.6 -1.3 -0.1 0.0 -0.4 1.0 -0.6 0.4 0.1
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.6 0.7 3.2 -1.3 0.0 0.0 -0.3 -0.4 -0.9 1.8 0.2
Whole body fat mass 0.7 2.8 7.0 -0.9 2.4 0.0 -2.6 1.5 1.2 -1.9 1.0
Leg fat mass (right) 0.9 3.5 9.8 -1.3 2.1 0.0 -3.1 2.1 1.3 -2.0 1.4
Arm predicted mass (right) 0.8 4.2 21.4 1.0 4.6 0.0 -0.6 -2.4 1.0 -2.0 -0.0
Pulse rate, automated reading 0.4 1.3 4.4 1.6 0.5 0.0 -1.0 2.1 0.3 -1.2 0.7
Alcohol intake frequency. 0.4 0.9 1.9 -1.1 0.6 0.0 -1.4 1.1 0.0 -0.9 1.2
Comparative height size at age 10 1.0 5.6 25.5 0.1 3.5 0.0 1.6 -5.0 1.1 -0.2 -1.7
Number of full sisters 0.3 0.4 1.1 -0.6 0.6 0.0 -1.0 -0.4 -0.1 -0.6 -1.0
Suffer from ‘nerves’ 0.6 1.0 5.3 -0.6 0.3 0.0 -0.0 2.3 0.0 -0.2 1.3
Overall health rating 1.6 3.4 12.9 -0.9 1.1 0.0 -2.6 3.6 0.2 -2.2 1.0
Chest pain or discomfort 1.2 1.7 5.4 -0.2 -0.8 0.0 1.1 1.3 -0.9 -2.3 -2.0
Had major operations 1.1 1.3 3.9 0.1 2.0 0.0 -1.4 -0.6 -0.5 -1.6 -1.2
Age at last live birth 0.2 0.3 1.2 -1.1 0.2 0.0 -0.4 -0.3 0.2 0.4 -0.7
Family relationship satisfaction 1.1 1.3 3.8 1.3 2.0 0.0 -1.4 -0.5 -0.1 -1.7 -0.2
Leg pain on walking 1.5 1.9 7.2 0.5 0.2 0.0 -1.5 1.8 0.3 1.4 2.7
Qualifications: NVQ or HND or HNC or equivalent 0.4 0.5 2.4 0.2 -0.6 0.0 0.0 1.6 0.0 -0.9 -0.8
Commuting to job workplace: Car/motor vehicle 2.5 2.8 8.1 -0.5 -0.1 0.0 -2.0 2.2 2.0 1.2 2.8
Illness, injury, bereavement, stress in last 2 years 0.5 0.6 3.0 -0.5 1.7 0.0 -0.8 -0.8 0.0 0.7 0.0
Medication: Aspirin 0.7 1.0 4.0 0.3 -2.0 0.0 1.1 0.6 -0.6 -1.1 -0.8
Supplements: Vitamin C 1.0 1.2 4.3 -2.1 0.4 0.0 -0.6 -0.8 1.0 -0.9 -1.4
Knee pain experienced in last month 1.5 2.3 5.3 1.4 2.3 0.0 -1.8 1.9 -0.3 -2.1 -0.0
Hypertension (Self-reported) 0.2 0.6 3.2 -0.6 -0.1 0.0 0.1 0.6 -0.3 -0.9 -1.8
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 1.4 1.6 4.0 -0.3 -0.7 0.0 -0.1 1.2 1.9 2.0 1.8
Illnesses of father: Heart disease 0.7 1.0 2.9 1.5 0.6 0.0 0.4 -1.4 -1.7 -0.3 0.2
Illnesses of siblings: Diabetes 0.9 1.1 6.7 -0.5 -0.8 0.0 0.2 2.6 -0.6 0.4 1.0
Smoking status: Previous 1.0 1.4 3.9 -1.7 0.9 0.0 -1.2 0.9 2.0 0.9 0.8
Forced expiratory volume in 1-second (FEV1), predicted 1.2 2.4 7.7 -0.2 2.1 0.0 1.4 -2.8 1.1 -0.4 -1.9
Whole body fat-free mass 0.9 5.1 21.9 1.5 4.7 0.0 -0.1 -3.3 1.0 -2.3 -0.1
Leg fat-free mass (right) 0.6 3.1 14.5 1.2 3.8 0.0 -0.7 -1.8 0.7 -2.1 0.5
Arm fat percentage (left) 0.9 3.6 11.0 -1.1 1.0 0.0 -3.3 3.1 0.8 -1.4 2.0
Average weekly red wine intake 0.4 0.6 1.9 -0.7 -0.6 0.0 1.4 0.3 0.5 1.0 -0.7
Handedness (chirality/laterality): Left-handed 1.0 1.1 3.6 0.7 1.9 0.0 -0.5 1.0 0.4 0.7 1.8
Mood swings 1.0 1.8 5.0 -1.1 -0.0 0.0 -1.9 2.2 0.6 0.0 2.0
Loneliness, isolation 0.6 0.9 1.5 0.6 1.0 0.0 -1.1 1.1 0.8 -1.2 1.1
Long-standing illness, disability or infirmity 0.4 0.6 3.0 -0.3 -0.0 0.0 -0.6 1.7 0.4 -0.7 0.9
Ever had bowel cancer screening 0.9 1.1 2.0 -1.3 0.1 0.0 -1.2 0.9 1.4 1.4 0.8
Diabetes diagnosed by doctor 1.3 2.2 5.0 -1.2 0.9 0.0 -1.7 2.2 1.9 1.4 1.3
Ever had stillbirth, spontaneous miscarriage or termination 1.2 1.3 3.3 -0.5 0.6 0.0 1.1 -1.4 -1.7 -0.7 -1.8
Friendships satisfaction 0.3 0.4 0.9 0.5 0.9 0.0 -0.5 -0.5 0.4 -0.9 -0.6
Qualifications: nursing, teaching 0.5 0.8 2.7 -0.1 1.6 0.0 -1.3 -0.1 -0.5 -1.0 -1.1
Commuting to job workplace: Walk 0.8 0.9 3.2 0.5 -0.1 0.0 0.9 -1.4 0.1 -0.9 -1.8
Eye problems/disorders: Cataract 0.8 0.9 3.4 0.6 -0.8 0.0 -0.5 1.9 0.1 -0.3 1.6
Mouth/teeth dental problems: Mouth ulcers 0.1 0.2 0.9 -0.0 -0.9 0.0 0.5 0.5 0.1 -0.5 0.4
Medication for cholesterol 0.5 0.7 2.9 0.3 1.7 0.0 -0.3 -1.2 -0.4 -0.7 0.6
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.7 0.8 2.8 -0.2 -0.2 0.0 1.3 -1.7 0.0 -0.4 -1.4
Back pain experienced in last month 1.6 2.4 11.7 0.3 -0.6 0.0 -1.0 3.4 -0.2 -0.7 2.3
Mineral and other dietary supplements 0.8 1.1 4.4 0.1 -1.4 0.0 -0.3 1.3 0.2 0.6 2.1
Breast cancer (self-reported) 0.2 0.3 1.0 0.6 -0.3 0.0 -0.0 0.6 0.1 -1.0 -0.5
Asthma (self-reported) 0.8 1.6 7.1 -1.8 -1.1 0.0 -0.3 2.7 0.4 0.9 0.6
Osteoporosis (self-reported) 0.7 0.9 2.1 -0.8 1.5 0.0 -1.1 -1.4 0.6 0.8 -0.7
Osteoarthritis (self-reported) 0.8 1.1 4.4 1.5 -0.1 0.0 -0.2 2.1 0.3 -0.9 1.0
Medication: Aspirin 0.6 0.8 3.0 0.1 -1.7 0.0 0.8 0.7 -0.5 -1.0 -0.9
Medication: Gliclazide 0.5 0.5 1.8 0.8 0.8 0.0 -0.6 0.4 1.3 0.6 0.8
Illnesses of father: None of the above (group 1) 1.0 1.2 4.5 0.3 0.8 0.0 0.5 -0.7 -0.6 -1.9 -2.1
Smoking status: Current 1.0 1.6 2.8 1.2 -1.5 0.0 1.7 -1.4 -0.9 -1.0 -1.5
Forced expiratory volume in 1-second (FEV1), predicted percentage 2.2 4.6 13.4 1.8 -0.6 0.0 1.7 -3.1 -1.9 -1.9 -3.7
Whole body water mass 0.9 5.0 21.6 1.6 4.6 0.0 -0.1 -3.2 0.9 -2.2 -0.1
Leg predicted mass (right) 0.6 3.0 14.3 1.1 3.8 0.0 -0.6 -1.8 0.6 -2.1 0.4
Arm fat mass (left) 0.7 3.0 8.6 -0.4 2.3 0.0 -2.9 1.7 1.0 -2.0 1.5
Number of self-reported non-cancer illnesses 0.6 1.0 4.5 -1.2 -0.8 0.0 -0.1 2.1 0.9 -0.5 0.0
Average weekly champagne plus white wine intake 0.5 0.7 3.7 0.2 0.6 0.0 -0.0 -1.9 -0.2 0.6 -1.1
Miserableness 0.3 0.5 1.4 -0.1 0.0 0.0 -0.8 1.2 1.0 -0.5 1.0
Guilty feelings 0.4 0.7 2.7 -0.4 -0.0 0.0 -0.6 1.6 -0.1 -1.4 0.4
Wears glasses or contact lenses 0.6 0.7 5.3 -0.3 0.5 0.0 0.1 0.2 0.3 -2.3 -0.4
Ever taken oral contraceptive pill 0.4 0.4 1.0 -0.9 0.6 0.0 -0.9 0.5 1.0 -0.1 0.4
Hearing aid user 0.9 1.0 2.8 1.1 -1.1 0.0 1.3 0.3 -1.7 -0.7 -1.0
Mother’s age at death 0.1 0.1 0.3 0.1 -0.4 0.0 -0.1 0.5 0.5 0.2 0.1
Financial situation satisfaction 0.5 0.6 2.0 -1.4 -1.0 0.0 -0.4 -0.5 -0.8 0.6 0.7
Tinnitus: Yes, now most or all of the time 0.2 0.3 1.1 0.2 -0.7 0.0 0.5 1.0 0.3 0.0 -0.3
Commuting to job workplace: Public transport 1.8 2.2 7.5 -0.7 -0.4 0.0 1.9 -1.6 -1.6 -0.5 -2.7
Eye problems/disorders: Glaucoma 0.4 0.5 2.6 -0.3 1.6 0.0 -0.5 0.4 0.7 -0.7 0.1
Medication: Blood pressure 0.5 0.9 3.6 -0.9 -0.7 0.0 -0.6 1.9 0.8 0.9 -0.5
Pain type(s) experienced in last month: Hip pain 1.1 1.4 4.8 -1.3 -0.5 0.0 -1.3 2.2 0.3 -0.3 1.5
Supplements: Fish oil (including cod liver oil) 0.3 0.4 1.3 -1.1 0.7 0.0 -0.6 -0.4 0.2 -0.3 -0.6
High cholesterol (Self-reported) 0.9 1.5 5.2 -2.3 -0.8 0.0 0.2 1.4 1.1 1.7 -0.4
Medication: Bendroflumethiazide 0.8 1.3 5.2 -0.5 -1.2 0.0 0.9 1.3 -2.3 -0.1 -0.9
Medication: Paracetamol 0.4 0.7 3.0 0.8 -0.3 0.0 -0.6 1.7 -0.5 -0.6 0.9
Medication: Lisinopril 0.2 0.3 1.2 0.8 -0.2 0.0 -0.4 -0.2 0.3 0.4 1.1
Medication: Atorvastatin 0.6 0.7 2.3 -0.3 -0.5 0.0 0.5 -0.2 -1.5 -1.2 -1.1
Illnesses of father: High blood pressure 0.4 0.5 2.5 -0.0 0.3 0.0 -0.6 1.6 0.3 0.8 0.4
Alcohol drinker status: Never 1.3 1.5 5.9 0.8 2.4 0.0 0.1 -1.4 -1.6 -0.5 -1.0
Ever smoked 1.0 1.7 3.7 0.7 -1.0 0.0 1.9 -1.8 -1.0 -1.3 -1.6
Basal metabolic rate 0.8 4.3 20.8 1.0 4.6 0.0 -0.7 -2.3 1.2 -2.3 0.2
Leg fat percentage (left) 1.3 4.8 16.2 -2.1 0.8 0.0 -4.0 3.3 1.3 -1.5 1.6
Arm fat-free mass (left) 0.9 4.5 22.5 1.0 4.7 0.0 -0.9 -2.4 0.9 -2.3 0.0
Number of operations (self-reported) 0.3 0.5 1.4 -0.8 1.2 0.0 -1.0 -0.6 0.4 -0.2 -0.5
Average weekly beer plus cider intake 0.6 0.9 2.4 0.9 1.6 0.0 0.2 -1.0 0.6 -0.2 -1.5
Irritability 0.3 0.5 2.3 -0.6 1.5 0.0 -0.0 -1.0 -0.2 0.5 -0.2
Risk taking 0.8 1.1 3.6 -1.9 0.4 0.0 -0.9 -0.3 -0.0 -1.7 -1.3
Ever had prostate specific antigen (PSA) test 0.4 0.5 2.6 -0.1 1.0 0.0 0.1 0.2 1.6 -0.3 0.4
Fractured/broken bones in last 5 years 0.7 0.9 2.2 0.8 0.7 0.0 0.4 -1.1 -1.1 -1.1 -1.5
Age started oral contraceptive pill 1.2 1.5 3.0 -0.1 -1.7 0.0 0.5 1.7 0.4 1.6 1.7
Diastolic blood pressure, automated reading 0.2 0.8 3.6 -0.7 0.5 0.0 -1.0 1.9 0.8 -0.3 0.2
Ever depressed for a whole week 2.6 3.3 15.0 -3.9 0.2 0.0 -1.3 -0.5 0.8 2.9 -0.2
Unable to work because of sickness or disability 0.3 0.4 1.2 -0.3 -0.4 0.0 0.4 0.9 1.1 -0.8 -0.5
Commuting to job workplace: Cycle 0.8 1.0 3.0 0.8 1.5 0.0 -0.6 -0.5 -0.7 -1.0 -1.7
Myopia 0.2 0.3 1.5 0.5 0.0 0.0 -0.1 -0.3 0.1 -1.2 -0.5
Vascular/heart problems diagnosed by doctor 0.3 0.9 4.2 0.4 0.4 0.0 -0.5 -0.3 0.4 1.4 2.0
Cholesterol lowering medication 1.0 1.5 6.0 -1.1 -0.7 0.0 0.0 2.5 1.3 1.5 0.4
Medication: Omeprazole (e.g. Zanprol) 1.0 1.2 2.8 -1.4 0.2 0.0 -1.0 0.9 1.4 1.7 1.2
Pain experienced in last month 0.9 1.5 3.8 -1.3 -0.9 0.0 0.9 -1.9 0.8 1.9 -0.6
Supplements: Calcium 1.2 1.3 5.8 0.1 2.4 0.0 -1.4 -0.6 1.4 0.2 -0.4
Basal cell carcinoma (self-reported) 0.4 0.5 2.2 -1.1 0.4 0.0 0.0 -0.5 0.2 1.5 -0.3
Heart attack/myocardial infarction (self-reported) 0.5 0.6 1.4 -1.2 -1.0 0.0 0.7 -0.9 -0.5 -0.0 -0.8
Deep venous thrombosis (DVT) (self-reported) 2.7 3.5 11.9 -1.0 -0.5 0.0 -1.5 1.8 2.8 1.3 3.5
Heart disease (siblings) 1.0 1.2 4.2 1.0 -2.1 0.0 0.3 2.0 0.6 0.1 0.6
Alcohol drinker status: Previous 0.3 0.3 1.5 -1.2 -0.5 0.0 0.0 -0.2 -0.2 0.4 0.6
Pack years of smoking 1.1 1.6 5.0 -0.4 -2.2 0.0 -0.6 0.9 2.0 0.6 1.3
Impedance of whole body 0.5 2.5 5.0 -2.1 -1.8 0.0 2.2 -0.8 0.7 1.5 -2.1
Leg fat mass (left) 0.9 3.5 10.2 -1.0 2.2 0.0 -3.2 2.0 1.3 -2.1 1.4
Arm predicted mass (left) 0.9 4.4 21.0 1.1 4.6 0.0 -0.8 -2.3 1.0 -2.5 0.0