Best TWAS P=3.17e-10 · Best GWAS P=8e-10 conditioned to 0.00742
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Artery Tibial | ATE1 | 0.19 | 0.02 | enet | 26 | 0.09 | 2.3e-07 | 2.7 | 5.2 | 2.2e-07 | -0.40 | 0.18 | 0.69 | FALSE |
2 | GTEx | Brain Cortex | RP11-500G22.2 | 0.66 | -0.01 | enet | 36 | 0.01 | 1.5e-01 | -5.6 | -6.3 | 3.2e-10 | 0.41 | 0.03 | 0.75 | TRUE |
3 | GTEx | Breast Mammary Tissue | RP11-500G22.2 | 0.28 | 0.04 | lasso | 4 | 0.09 | 3.1e-05 | 4.1 | -6.2 | 4.2e-10 | 0.62 | 0.04 | 0.80 | TRUE |