Best TWAS P=3.73e-08 · Best GWAS P=6.37e-08 conditioned to 0.331
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | C14orf39 | 0.08 | 0.05 | lasso | 8 | 0.06 | 2.1e-05 | 4.6 | -5.5 | 3.7e-08 | -0.91 | 0.05 | 0.95 | TRUE |
| 2 | The Cancer Genome Atlas | Lung Adenocarcinoma | C14orf39 | 0.02 | 0.02 | blup | 37 | 0.02 | 4.2e-03 | 4.7 | -5.3 | 1.5e-07 | -0.66 | 0.02 | 0.79 | FALSE |
| 3 | The Cancer Genome Atlas | Pheochromocytoma and Paraganglioma | C14orf39 | 0.08 | 0.05 | blup | 37 | 0.05 | 4.2e-03 | 4.8 | -5.2 | 1.5e-07 | -0.64 | 0.02 | 0.84 | FALSE |
| 4 | The Cancer Genome Atlas | Prostate Adenocarcinoma | C14orf39 | 0.08 | 0.09 | blup | 37 | 0.11 | 1.8e-11 | 5.1 | -5.2 | 1.6e-07 | -0.67 | 0.02 | 0.98 | FALSE |