Best TWAS P=9.67e-08 · Best GWAS P=4.07e-08 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Tibial | L3MBTL2 | 0.05 | 0.06 | lasso | 3 | 0.05 | 1.0e-04 | -5.3 | 5.3 | 9.7e-08 | -0.99 | 0.01 | 0.98 | TRUE |
| 2 | GTEx | Cells EBV-transformed lymphocytes | L3MBTL2 | 0.12 | 0.08 | lasso | 6 | 0.05 | 1.0e-02 | -5.4 | -5.3 | 1.2e-07 | 0.98 | 0.01 | 0.93 | FALSE |
| 3 | YFS | Blood | EP300 | 0.05 | 0.04 | blup | 284 | 0.05 | 5.2e-15 | -5.5 | 5.3 | 1.2e-07 | -0.79 | 0.01 | 0.99 | FALSE |