Best TWAS P=9.39e-09 · Best GWAS P=5.44e-07 conditioned to 0.217
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Brain Frontal Cortex BA9 | GPX1 | 0.16 | 0.06 | lasso | 6 | 0.15 | 7.9e-05 | 3.7 | 5.7 | 9.4e-09 | -0.72 | 0.04 | 0.70 | TRUE |
2 | GTEx | Lung | GPX1 | 0.04 | 0.02 | enet | 13 | 0.04 | 5.7e-04 | -3.9 | 5.2 | 1.7e-07 | -0.50 | 0.07 | 0.41 | FALSE |